6UGH
Cryo-EM structure of the apo form of human PRMT5:MEP50 complex at a resolution of 3.4 angstrom
Summary for 6UGH
Entry DOI | 10.2210/pdb6ugh/pdb |
EMDB information | 20764 7137 |
Descriptor | Protein arginine N-methyltransferase 5, Methylosome protein 50 (2 entities in total) |
Functional Keywords | prmt5, methyltransferase, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 114284.91 |
Authors | Zhou, W.,Yadav, G.P.,Jiang, Q.-X.,Li, C. (deposition date: 2019-09-26, release date: 2020-12-09, Last modification date: 2024-03-20) |
Primary citation | Zhou, W.,Yadav, G.P.,Jiang, Q.-X.,Li, C. A 3.4-angstrom cryo-EM structure of the apo form of hu-man PRMT5:MEP50 complex reveals sequential catalysis of symmetric methyl transfer To Be Published, |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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