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8F7L

Human NAMPT in complex with substrate NAM and small molecule activator ZN-29-S

Summary for 8F7L
Entry DOI10.2210/pdb8f7l/pdb
DescriptorNicotinamide phosphoribosyltransferase, NICOTINAMIDE, PHOSPHATE ION, ... (6 entities in total)
Functional Keywordsnad biosynthesis, enzyme activator, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight114802.98
Authors
Ratia, K.,Xiong, R.,Shen, Z.,Thatcher, G.R. (deposition date: 2022-11-18, release date: 2023-11-29)
Primary citationRatia, K.,Xiong, R.,Shen, Z.,Thatcher, G.R.
Human NAMPT in complex with substrate NAM and small molecule activator ZN-29-S
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

227561

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