4U1X
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![BU of 4u1x by Molmil](/molmil-images/mine/4u1x) | Full length GluA2-kainate-(R,R)-2b complex crystal form B | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, ... | 著者 | Chen, L, Gouaux, E. | 登録日 | 2014-07-16 | 公開日 | 2014-08-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.301 Å) | 主引用文献 | Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States. Cell, 158, 2014
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4UBH
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![BU of 4ubh by Molmil](/molmil-images/mine/4ubh) | Resting state of rat cysteine dioxygenase Y157F variant | 分子名称: | CHLORIDE ION, Cysteine dioxygenase type 1, FE (II) ION, ... | 著者 | Tchesnokov, E.P, Fellner, M, Jameson, G.N.L, Wilbanks, S.M. | 登録日 | 2014-08-13 | 公開日 | 2015-02-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Crystal structure of cysteine dioxygenase mutant To be published
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4U2Q
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![BU of 4u2q by Molmil](/molmil-images/mine/4u2q) | Full-length AMPA subtype ionotropic glutamate receptor GluA2 in complex with partial agonist kainate | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2 | 著者 | Duerr, K.L, Chen, L, Gouaux, E. | 登録日 | 2014-07-17 | 公開日 | 2014-08-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.5247 Å) | 主引用文献 | Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States. Cell, 158, 2014
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4U4C
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![BU of 4u4c by Molmil](/molmil-images/mine/4u4c) | The molecular architecture of the TRAMP complex reveals the organization and interplay of its two catalytic activities | 分子名称: | 1,2-ETHANEDIOL, ATP-dependent RNA helicase DOB1, CHLORIDE ION, ... | 著者 | Falk, S, Weir, J.R, Hentschel, J, Reichelt, P, Bonneau, F, Conti, E. | 登録日 | 2014-07-23 | 公開日 | 2014-09-24 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Molecular Architecture of the TRAMP Complex Reveals the Organization and Interplay of Its Two Catalytic Activities. Mol.Cell, 55, 2014
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4UFI
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![BU of 4ufi by Molmil](/molmil-images/mine/4ufi) | Mouse Galactocerebrosidase complexed with aza-galacto-fagomine AGF | 分子名称: | (3R,4S,5R)-3-(hydroxymethyl)-1,2-diazinane-4,5-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E. | 登録日 | 2015-03-17 | 公開日 | 2015-03-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease. Chem.Sci., 6, 2015
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4U2V
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![BU of 4u2v by Molmil](/molmil-images/mine/4u2v) | Bak BH3-in-Groove dimer (GFP) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Green fluorescent protein,Bcl-2 homologous antagonist/killer | 著者 | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | 登録日 | 2014-07-18 | 公開日 | 2014-09-10 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Bak Core and Latch Domains Separate during Activation, and Freed Core Domains Form Symmetric Homodimers. Mol.Cell, 55, 2014
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4TX9
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![BU of 4tx9 by Molmil](/molmil-images/mine/4tx9) | Crystal structure of HisAp from Streptomyces sviceus with degraded ProFAR | 分子名称: | AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, Phosphoribosyl isomerase A, SULFATE ION | 著者 | Michalska, K, Verduzco-Castro, E.A, Endres, M, Barona-Gomez, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2014-07-02 | 公開日 | 2014-08-06 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Co-occurrence of analogous enzymes determines evolution of a novel ( beta alpha )8-isomerase sub-family after non-conserved mutations in flexible loop. Biochem. J., 473, 2016
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4TYG
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![BU of 4tyg by Molmil](/molmil-images/mine/4tyg) | Structural analysis of the human Fibroblast Growth Factor Receptor 4 Kinase | 分子名称: | ACETATE ION, Fibroblast growth factor receptor 4 | 著者 | Lesca, E, Lammens, A, Huber, R, Augustin, M. | 登録日 | 2014-07-08 | 公開日 | 2014-09-24 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural analysis of the human fibroblast growth factor receptor 4 kinase. J.Mol.Biol., 426, 2014
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4TYQ
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![BU of 4tyq by Molmil](/molmil-images/mine/4tyq) | Crystal structure of an adenylate kinase mutant--AKm2 | 分子名称: | Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, CALCIUM ION, ... | 著者 | Moon, S, Bae, E. | 登録日 | 2014-07-09 | 公開日 | 2014-11-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structures of thermally stable adenylate kinase mutants designed by local structural entropy optimization and structure-guided mutagenesis J KOREAN SOC APPL BIOL CHEM, 57, 2014
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4U5G
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6KA4
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![BU of 6ka4 by Molmil](/molmil-images/mine/6ka4) | Cryo-EM structure of the AtMLKL3 tetramer | 分子名称: | F22L4.1 protein | 著者 | Lisa, M, Huang, M, Zhang, X, Ryohei, T.N, Leila, B.K, Isabel, M.L.S, Florence, J, Viera, K, Dmitry, L, Jane, E.P, James, M.M, Kay, H, Paul, S.L, Chai, J, Takaki, M. | 登録日 | 2019-06-20 | 公開日 | 2020-09-23 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structure of the AtMLKL3 tetramer To Be Published
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4U67
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![BU of 4u67 by Molmil](/molmil-images/mine/4u67) | Crystal structure of the large ribosomal subunit (50S) of Deinococcus radiodurans containing a three residue insertion in L22 | 分子名称: | 23s RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A. | 登録日 | 2014-07-28 | 公開日 | 2015-08-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | 主引用文献 | The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel. Structure, 25, 2017
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4U1Y
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![BU of 4u1y by Molmil](/molmil-images/mine/4u1y) | Full length GluA2-FW-(R,R)-2b complex | 分子名称: | 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2, ... | 著者 | Chen, L, Gouaux, E. | 登録日 | 2014-07-16 | 公開日 | 2014-08-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.8999 Å) | 主引用文献 | Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States. Cell, 158, 2014
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4TWJ
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![BU of 4twj by Molmil](/molmil-images/mine/4twj) | The structure of Sir2Af2 bound to a myristoylated histone peptide | 分子名称: | ACETATE ION, GLYCEROL, Histone H4 peptide, ... | 著者 | Ringel, A.E, Roman, C, Wolberger, C. | 登録日 | 2014-06-30 | 公開日 | 2014-12-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Alternate deacylating specificities of the archaeal sirtuins Sir2Af1 and Sir2Af2. Protein Sci., 23, 2014
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4TY0
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![BU of 4ty0 by Molmil](/molmil-images/mine/4ty0) | Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with linear intermediate 5' pppA(3',5')pG | 分子名称: | ACETATE ION, Cyclic AMP-GMP synthase, MAGNESIUM ION, ... | 著者 | Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A. | 登録日 | 2014-07-07 | 公開日 | 2014-08-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity. Cell, 158, 2014
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4TXZ
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![BU of 4txz by Molmil](/molmil-images/mine/4txz) | Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with nonhydrolyzable GTP | 分子名称: | Cyclic AMP-GMP synthase, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | 著者 | Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A. | 登録日 | 2014-07-07 | 公開日 | 2014-08-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity. Cell, 158, 2014
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4TYP
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![BU of 4typ by Molmil](/molmil-images/mine/4typ) | Crystal structure of an adenylate kinase mutant--AKm1 | 分子名称: | Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, ZINC ION | 著者 | Moon, S, Bae, E. | 登録日 | 2014-07-09 | 公開日 | 2014-11-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structures of thermally stable adenylate kinase mutants designed by local structural entropy optimization and structure-guided mutagenesis J KOREAN SOC APPL BIOL CHEM, 57, 2014
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4U6Y
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![BU of 4u6y by Molmil](/molmil-images/mine/4u6y) | Crystal Structure of HLA-A*0201 in complex with FLNDK, a 15 mer self-peptide | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Gras, S, Chabrol, E, Rossjohn, J. | 登録日 | 2014-07-30 | 公開日 | 2014-12-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.467 Å) | 主引用文献 | Naturally Processed Non-canonical HLA-A*02:01 Presented Peptides. J.Biol.Chem., 290, 2015
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4UD9
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![BU of 4ud9 by Molmil](/molmil-images/mine/4ud9) | Thrombin in complex with 5-chlorothiophene-2-carboxamide | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-CHLORO-2-THIOPHENECARBOXAMIDE, ... | 著者 | Ruehmann, E, Heine, A, Klebe, G. | 登録日 | 2014-12-09 | 公開日 | 2015-08-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.124 Å) | 主引用文献 | Fragments Can Bind Either More Enthalpy or Entropy-Driven: Crystal Structures and Residual Hydration Pattern Suggest Why. J.Med.Chem., 58, 2015
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4UFS
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![BU of 4ufs by Molmil](/molmil-images/mine/4ufs) | |
4UPU
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![BU of 4upu by Molmil](/molmil-images/mine/4upu) | Crystal structure of IP3 3-K calmodulin binding region in complex with Calmodulin | 分子名称: | CALCIUM ION, CALMODULIN, GLYCEROL, ... | 著者 | Franco-Echevarria, E, Banos-Sanz, J.I, Monterroso, B, Round, A, Sanz-Aparicio, J, Gonzalez, B. | 登録日 | 2014-06-18 | 公開日 | 2014-08-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | A New Calmodulin Binding Motif for Inositol 1,4,5-Trisphosphate 3-Kinase Regulation. Biochem.J., 463, 2014
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4U5M
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![BU of 4u5m by Molmil](/molmil-images/mine/4u5m) | Structure of a left-handed DNA G-quadruplex | 分子名称: | DNA (28-MER), MAGNESIUM ION, POTASSIUM ION | 著者 | Schmitt, E, Mechulam, Y, Phan, A.T, Brahim, H, Chung, W.J, Lim, K.W. | 登録日 | 2014-07-25 | 公開日 | 2015-02-25 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of a left-handed DNA G-quadruplex. Proc.Natl.Acad.Sci.USA, 112, 2015
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4U5W
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![BU of 4u5w by Molmil](/molmil-images/mine/4u5w) | Crystal Structure of HIV-1 Nef-SF2 Core Domain in Complex with the Src Family Kinase Hck SH3-SH2 Tandem Regulatory Domains | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, IODIDE ION, Protein Nef, ... | 著者 | Alvarado, J.J, Yeh, J.I, Smithgall, T.E. | 登録日 | 2014-07-25 | 公開日 | 2014-08-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Interaction with the Src Homology (SH3-SH2) Region of the Src-family Kinase Hck Structures the HIV-1 Nef Dimer for Kinase Activation and Effector Recruitment. J.Biol.Chem., 289, 2014
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4U66
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4UEH
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![BU of 4ueh by Molmil](/molmil-images/mine/4ueh) | Thrombin in complex with benzamidine | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BENZAMIDINE, GLYCEROL, ... | 著者 | Ruehmann, E, Heine, A, Klebe, G. | 登録日 | 2014-12-17 | 公開日 | 2015-08-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | 主引用文献 | Fragments Can Bind Either More Enthalpy or Entropy-Driven: Crystal Structures and Residual Hydration Pattern Suggest Why. J.Med.Chem., 58, 2015
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