PDB: 13252 件ウェブページステータス検索Chemie searchBIRD

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6E2H	Crystal structure of human Ash2L (SPRY domain and SDI motif) in complex with full length DPY-30 分子名称: Protein dpy-30 homolog, Set1/Ash2 histone methyltransferase complex subunit ASH2 著者 Joshi, M, Brunzelle, J.S, Couture, J.F. 登録日 2018-07-11 公開日 2018-08-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.236 Å) 主引用文献 Structural Analysis of the Ash2L/Dpy-30 Complex Reveals a Heterogeneity in H3K4 Methylation. Structure, 26, 2018
1WP9	Crystal structure of Pyrococcus furiosus Hef helicase domain 分子名称: ATP-dependent RNA helicase, putative, PHOSPHATE ION 著者 Nishino, T, Komori, K, Tsuchiya, D, Ishino, Y, Morikawa, K. 登録日 2004-08-31 公開日 2005-02-01 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structure and Functional Implications of Pyrococcus furiosus Hef Helicase Domain Involved in Branched DNA Processing Structure, 13, 2005
7NQP	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound LvD1009 分子名称: 14-3-3 protein sigma, 2-bromanyl-4-(2-phenylimidazol-1-yl)benzaldehyde, MAGNESIUM ION, ... 著者 Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. 登録日 2021-03-02 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
8P81	Crystal structure of human Cdk12/Cyclin K in complex with inhibitor SR-4835 分子名称: Cyclin-K, Cyclin-dependent kinase 12, ~{N}-[[5,6-bis(chloranyl)-1~{H}-benzimidazol-2-yl]methyl]-9-(1-methylpyrazol-4-yl)-2-morpholin-4-yl-purin-6-amine 著者 Anand, K, Schmitz, M, Geyer, M. 登録日 2023-05-31 公開日 2023-11-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 The reversible inhibitor SR-4835 binds Cdk12/cyclin K in a noncanonical G-loop conformation. J.Biol.Chem., 300, 2023
1OOP	The Crystal Structure of Swine Vesicular Disease Virus 分子名称: Coat protein VP1, Coat protein VP2, Coat protein VP3, ... 著者 Fry, E.E, Knowles, N.J, Newman, J.W.I, Wilsden, G, Rao, Z, King, A.M.Q, Stuart, D.I. 登録日 2003-03-04 公開日 2003-04-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal Structure of Swine Vesicular Disease Virus and Implications for Host Adaptation J.Virol., 77, 2003
1RUI	RHINOVIRUS 14 MUTANT S1223G COMPLEXED WITH ANTIVIRAL COMPOUND WIN 52084 分子名称: 5-(7-(5-HYDRO-4-METHYL-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, RHINOVIRUS 14 著者 Hadfield, A, Oliveira, M.A, Kim, K.H, Minor, I, Kremer, M.J, Heinz, B.A, Shepard, D, Pevear, D.C, Rueckert, R.R, Rossmann, M.G. 登録日 1995-06-09 公開日 1995-11-14 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural studies on human rhinovirus 14 drug-resistant compensation mutants. J.Mol.Biol., 253, 1995
1RUG	RHINOVIRUS 14 MUTANT N1219S COMPLEXED WITH ANTIVIRAL COMPOUND WIN 52035 分子名称: 5-(5-(4-(4,5-DIHYDRO-2-OXAZOLY)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE, RHINOVIRUS 14 著者 Hadfield, A, Oliveira, M.A, Kim, K.H, Minor, I, Kremer, M.J, Heinz, B.A, Shepard, D, Pevear, D.C, Rueckert, R.R, Rossmann, M.G. 登録日 1995-06-09 公開日 1995-11-14 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural studies on human rhinovirus 14 drug-resistant compensation mutants. J.Mol.Biol., 253, 1995
2ERM	Solution structure of a biologically active human FGF-1 monomer, complexed to a hexasaccharide heparin-analogue 分子名称: 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, Heparin-binding growth factor 1, ISOPROPYL ALCOHOL 著者 Canales, A, Lozano, R, Nieto, P.M, Martin-Lomas, M, Gimenez-Gallego, G, Jimenez-Barbero, J. 登録日 2005-10-25 公開日 2006-10-03 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution NMR structure of a human FGF-1 monomer, activated by a hexasaccharide heparin-analogue. Febs J., 273, 2006
1RUF	RHINOVIRUS 14 (HRV14) (MUTANT WITH ASN 1 219 REPLACED BY ALA (N219A IN CHAIN 1) 分子名称: RHINOVIRUS 14 著者 Hadfield, A, Oliveira, M.A, Kim, K.H, Minor, I, Kremer, M.J, Heinz, B.A, Shepard, D, Pevear, D.C, Rueckert, R.R, Rossmann, M.G. 登録日 1995-06-09 公開日 1995-11-14 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural studies on human rhinovirus 14 drug-resistant compensation mutants. J.Mol.Biol., 253, 1995
1RUJ	RHINOVIRUS 14 MUTANT WITH SER 1 223 REPLACED BY GLY (S1223G) 分子名称: RHINOVIRUS 14 著者 Hadfield, A, Oliveira, M.A, Kim, K.H, Minor, I, Kremer, M.J, Heinz, B.A, Shepard, D, Pevear, D.C, Rueckert, R.R, Rossmann, M.G. 登録日 1995-06-09 公開日 1995-11-14 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural studies on human rhinovirus 14 drug-resistant compensation mutants. J.Mol.Biol., 253, 1995
1RUC	RHINOVIRUS 14 MUTANT N1105S COMPLEXED WITH ANTIVIRAL COMPOUND WIN 52035 分子名称: 5-(5-(4-(4,5-DIHYDRO-2-OXAZOLY)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE, RHINOVIRUS 14 著者 Hadfield, A, Oliveira, M.A, Kim, K.H, Minor, I, Kremer, M.J, Heinz, B.A, Shepard, D, Pevear, D.C, Rueckert, R.R, Rossmann, M.G. 登録日 1995-06-09 公開日 1995-11-14 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural studies on human rhinovirus 14 drug-resistant compensation mutants. J.Mol.Biol., 253, 1995
2C6B	Solution structure of the C4 zinc-finger domain of HDM2 分子名称: UBIQUITIN-PROTEIN LIGASE E3 MDM2, ZINC ION 著者 Yu, G.W, Allen, M.D, Andreeva, A, Fersht, A.R, Bycroft, M. 登録日 2005-11-08 公開日 2006-01-04 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the C4 Zinc Finger Domain of Hdm2. Protein Sci., 15, 2006
4LYN	Crystal structure of cyclin-dependent kinase 2 (cdk2-wt) complex with (2s)-n-(5-(((5-tert-butyl-1,3-oxazol-2-yl)methyl)sulfanyl)-1,3-thiazol-2-yl)-2-phenylpropanamide 分子名称: (2S)-N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)-2-phenylpropanamide, Cyclin-dependent kinase 2 著者 Sack, J.S. 登録日 2013-07-31 公開日 2013-10-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of Aminothiazole Inhibitors of Cyclin-Dependent Kinase 2: Synthesis, X-Ray Crystallographic Analysis, and Biological Activities J.Med.Chem., 45, 2002
7NYF	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-131 分子名称: 14-3-3 protein sigma, 4-[(3~{S})-3-oxidanylpiperidin-1-yl]sulfonylbenzaldehyde, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-03-22 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NZ6	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-125 分子名称: 14-3-3 protein sigma, 4-[4-(2-methoxyethyl)piperazin-1-yl]sulfonylbenzaldehyde, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-03-23 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7O3F	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-117 分子名称: 1-methyl-4-(4-methylphenyl)sulfonyl-1,4-diazepane, 14-3-3 protein sigma, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-04-01 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NVI	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-186 分子名称: 14-3-3 protein sigma, 4-[(7-chloranyl-2,3-dihydro-1,4-benzoxazin-4-yl)sulfonyl]benzaldehyde, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-03-15 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
2C6A	Solution structure of the C4 zinc-finger domain of HDM2 分子名称: UBIQUITIN-PROTEIN LIGASE E3 MDM2, ZINC ION 著者 Yu, G.W, Allen, M.D, Andreeva, A, Fersht, A.R, Bycroft, M. 登録日 2005-11-08 公開日 2006-01-04 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the C4 Zinc Finger Domain of Hdm2. Protein Sci., 15, 2006
7NY4	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-130 分子名称: 14-3-3 protein sigma, 4-(3-oxidanylidenepiperazin-1-yl)sulfonylbenzaldehyde, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-03-20 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NZG	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-122 分子名称: 14-3-3 protein sigma, 4-(4-methoxypiperidin-1-yl)sulfonylbenzaldehyde, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-03-24 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7O3P	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-116 分子名称: 14-3-3 protein sigma, 2-chloranyl-6-methoxy-1-(4-methylphenyl)sulfonyl-benzimidazole, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-04-02 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7O57	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-157 分子名称: 14-3-3 protein sigma, 3-morpholin-4-yl-4-nitro-benzaldehyde, Transcription factor p65 著者 Wolter, M, Ottmann, C. 登録日 2021-04-08 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7O5D	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-160 分子名称: 14-3-3 protein sigma, 4-methanoyl-~{N}-[(4-methoxyphenyl)methyl]benzamide, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-04-08 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7O5U	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-168 分子名称: 14-3-3 protein sigma, 4-methanoyl-~{N}-[(1-methylimidazol-2-yl)methyl]benzamide, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-04-09 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NXY	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-181 分子名称: 14-3-3 protein sigma, 4-[(6-fluoranyl-3,4-dihydro-2~{H}-quinolin-1-yl)sulfonyl]benzaldehyde, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-03-19 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021

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