PDB: 47720 件ウェブページステータス検索Chemie searchBIRD

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6HKO	Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP 分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... 著者 Tafur, L, Sadian, Y, Weis, F, Muller, C.W. 登録日 2018-09-07 公開日 2019-04-03 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.42 Å) 主引用文献 The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
4PDW	A benzonitrile analogue inhibits rhinovirus replication 分子名称: 4-[(4,5-dimethoxy-2-nitrophenyl)acetyl]benzonitrile, Capsid protein VP4/VP2, GLYCEROL, ... 著者 Querol-Audi, J, Guerra, P, Lacroix, C, Roche, M, Franco, D, Froeyen, M, Terme, T, Vanelle, P, Neyts, J, Leyssen, P, Verdaguer, N. 登録日 2014-04-22 公開日 2014-07-02 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A novel benzonitrile analogue inhibits rhinovirus replication. J.Antimicrob.Chemother., 69, 2014
1L0L	structure of bovine mitochondrial cytochrome bc1 complex with a bound fungicide famoxadone 分子名称: Cytochrome B, Cytochrome c1, heme protein, ... 著者 Gao, X, Wen, X, Yu, C.A, Esser, L, Tsao, S, Quinn, B, Zhang, L, Yu, L, Xia, D. 登録日 2002-02-11 公開日 2003-04-08 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The Crystal Structure of Mitochondrial Cytochrome bc1 in Complex with Famoxadone: The Role of Aromatic-Aromatic Interaction in Inhibition Biochemistry, 41, 2003
4PKO	Crystal structure of the Football-shaped GroEL-GroES2-(ADPBeFx)14 complex 分子名称: 10 kDa chaperonin, 60 kDa chaperonin, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Fei, X, Ye, X, Laronde-Leblanc, N, Lorimer, G.H. 登録日 2014-05-15 公開日 2014-08-20 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.84 Å) 主引用文献 Formation and structures of GroEL:GroES2 chaperonin footballs, the protein-folding functional form. Proc.Natl.Acad.Sci.USA, 111, 2014
4UU0	CRYSTAL STRUCTURE OF (SR) CALCIUM-ATPASE E2(TG) IN THE PRESENCE OF 14:1 PC 分子名称: GLYCEROL, MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, ... 著者 Drachmann, N.D, Olesen, C, Moeller, J.V, Guo, Z, Nissen, P, Bublitz, M. 登録日 2014-07-24 公開日 2014-10-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Comparing Crystal Structures of Ca(2+) -ATPase in the Presence of Different Lipids. FEBS J., 281, 2014
4UX6	The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS) 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, NITRIC OXIDE SYNTHASE, INDUCIBLE, ... 著者 Cheshire, D.R, Andrews, G, Beaton, H.G, Birkinshaw, T, Boughton-Smith, N, Connolly, S, Cook, T.R, Cooper, A, Cooper, S.L, Cox, D, Dixon, J, Gensmantel, N, Hamley, P.J, Harrison, R, Hartopp, P, Kack, H, Luker, T, Mete, A, Millichip, I, Nicholls, D.J, Pimm, A.D, St-Gallay, S.A, Wallace, A.V. 登録日 2014-08-19 公開日 2014-10-08 最終更新日 2018-01-17 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The Discovery of Novel, Potent and Highly Selective Inhibitors of Inducible Nitric Oxide Synthase (Inos). Bioorg.Med.Chem.Lett., 21, 2011
8T1I	Atomic model of the mammalian Mediator complex with MED26 subunit 分子名称: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... 著者 Zhao, H, Asturias, F. 登録日 2023-06-02 公開日 2024-06-12 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (4.68 Å) 主引用文献 An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II. Mol.Cell, 84, 2024
8T9D	CryoEM structure of TR-TRAP 分子名称: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... 著者 Zhao, H, Asturias, F. 登録日 2023-06-23 公開日 2024-07-03 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (4.66 Å) 主引用文献 An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II. Mol.Cell, 84, 2024
8T1L	Atomic model of the mammalian mouse Mediator complex with CKM module 分子名称: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... 著者 Zhao, H, Asturias, F. 登録日 2023-06-02 公開日 2024-07-03 実験手法 ELECTRON MICROSCOPY (4.83 Å) 主引用文献 A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers. To Be Published
6KE6	3.4 angstrom cryo-EM structure of yeast 90S small subunit preribosome 分子名称: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... 著者 Du, Y, Ye, K, An, W. 登録日 2019-07-03 公開日 2020-08-05 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 3.4 angstrom cryo-EM structure of yeast 90S small subunit preribosome To be published
8GLV	96-nm repeat unit of doublet microtubules from Chlamydomonas reinhardtii flagella 分子名称: 28 kDa inner dynein arm light chain, axonemal, AAA+ ATPase domain-containing protein, ... 著者 Walton, T, Brown, A. 登録日 2023-03-23 公開日 2023-05-31 最終更新日 2023-06-28 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Axonemal structures reveal mechanoregulatory and disease mechanisms. Nature, 618, 2023
6B8H	Mosaic model of yeast mitochondrial ATP synthase monomer 分子名称: AATP synthase subunit g, ATP synthase catalytic sector F1 epsilon subunit, ATP synthase protein 8, ... 著者 Guo, H, Bueler, S.A, Rubinstein, J.L. 登録日 2017-10-07 公開日 2018-01-17 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Atomic model for the dimeric FO region of mitochondrial ATP synthase. Science, 358, 2017
5N9J	Core Mediator of transcriptional regulation 分子名称: Mediator Complex Subunit 9, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... 著者 Nozawa, K, Schneider, T.R, Cramer, P. 登録日 2017-02-25 公開日 2017-05-17 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Core Mediator structure at 3.4 Angstrom extends model of transcription initiation complex. Nature, 545, 2017
6LQT	Cryo-EM structure of 90S small subunit preribosomes in transition states (State E) 分子名称: 13 kDa ribonucleoprotein-associated protein, 18S pre-rRNA, 40S ribosomal protein S1-A, ... 著者 Du, Y, Ye, K. 登録日 2020-01-14 公開日 2020-09-16 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states. Science, 369, 2020
6LQQ	Cryo-EM structure of 90S small subunit preribosomes in transition states (State B) 分子名称: 13 kDa ribonucleoprotein-associated protein, 18S pre-rRNA, 40S ribosomal protein S1-A, ... 著者 Du, Y, Ye, K. 登録日 2020-01-14 公開日 2020-09-16 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states. Science, 369, 2020
6LQV	Cryo-EM structure of 90S small subunit preribosomes in transition states (State C1) 分子名称: 13 kDa ribonucleoprotein-associated protein, 18S pre-rRNA, 40S ribosomal protein S11-A, ... 著者 Du, Y, Ye, K. 登録日 2020-01-14 公開日 2020-09-16 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states. Science, 369, 2020
6C0F	Yeast nucleolar pre-60S ribosomal subunit (state 2) 分子名称: 5.8S rRNA, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... 著者 Sanghai, Z.A, Miller, L, Barandun, J, Hunziker, M, Chaker-Margot, M, Klinge, S. 登録日 2017-12-29 公開日 2018-03-14 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Modular assembly of the nucleolar pre-60S ribosomal subunit. Nature, 556, 2018
6W1S	Atomic model of the mammalian Mediator complex 分子名称: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... 著者 Zhao, H, Young, N, Asturias, F. 登録日 2020-03-04 公開日 2021-03-10 実験手法 ELECTRON MICROSCOPY (4.02 Å) 主引用文献 A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers. Cell, 178, 2019
6LQR	Cryo-EM structure of 90S small subunit preribosomes in transition states (State C) 分子名称: 13 kDa ribonucleoprotein-associated protein, 18S pre-rRNA, 40S ribosomal protein S1-A, ... 著者 Du, Y, Ye, K. 登録日 2020-01-14 公開日 2020-09-16 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (8.6 Å) 主引用文献 Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states. Science, 369, 2020
6CP5	Monomer yeast ATP synthase Fo reconstituted in nanodisc with inhibitor of oligomycin bound generated from focused refinement. 分子名称: ATP synthase protein 8, ATP synthase subunit 4, mitochondrial, ... 著者 Srivastava, A.P, Luo, M, Symersky, J, Liao, M.F, Mueller, D.M. 登録日 2018-03-13 公開日 2018-04-11 最終更新日 2020-01-15 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane. Science, 360, 2018
6CM1	MT1-MMP HPX Domain with Blade 2 Loop Bound to Nanodiscs 分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, CHLORIDE ION, ... 著者 Marcink, T.C, Van Doren, S.R. 登録日 2018-03-02 公開日 2018-12-12 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 MT1-MMP Binds Membranes by Opposite Tips of Its beta Propeller to Position It for Pericellular Proteolysis. Structure, 27, 2019
7NRO	Crystal structure of AlkB in complex with manganese and N-(4-((6-((carboxymethyl)carbamoyl)-5-hydroxypyridin-2-yl)amino)phenyl)-N-oxohydroxylammonium 分子名称: 2-[[6-[(4-nitrophenyl)amino]-3-oxidanyl-pyridin-2-yl]carbonylamino]ethanoic acid, Alpha-ketoglutarate-dependent dioxygenase AlkB, MANGANESE (II) ION 著者 Shishodia, S, Maheswaran, P, Leissing, T, Aik, W.S, McDonough, M.A, Schofield, C.J. 登録日 2021-03-04 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Structure-Based Design of Selective Fat Mass and Obesity Associated Protein (FTO) Inhibitors. J.Med.Chem., 64, 2021
6D7I	CTX-M-14 Apoenzyme D233N Point Mutant 分子名称: Beta-lactamase 著者 Kemp, M, Nichols, D, Chen, Y. 登録日 2018-04-24 公開日 2019-07-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 The Role of Asp-Asp Short Hydrogen Bond in Maintaining Active Site Integrity of CTX-M Beta-Lactamase To be Published
6D7H	CTX-M-14 Apoenzyme 分子名称: Beta-lactamase, PHOSPHATE ION, POTASSIUM ION 著者 Kemp, M, Nichols, D, Chen, Y. 登録日 2018-04-24 公開日 2019-07-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 The Role of Asp-Asp Short Hydrogen Bond in Maintaining Active Site Integrity of CTX-M Beta-Lactamase To be Published
4D0S	Mtb InhA complex with Pyradizinone compound 14 分子名称: 1-{4-[(acetylamino)methyl]phenyl}-4-(4-chlorophenoxy)-6-oxo-1,6-dihydropyridazine-3-carboxamide, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], MAGNESIUM ION, ... 著者 Read, J.A, Breed, J, Madhavapeddi, P, Lange, S. 登録日 2014-04-29 公開日 2015-05-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Pyridazinones: A Novel Scaffold with Excellent Physicochemical Properties and Safety Profile for a Clinically Validated Target of Mycobacterium Tuberculosis To be Published

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