PDB: 36667 件ウェブページステータス検索Chemie searchBIRD

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7MA7	HIV-1 Protease (I84V) in Complex with UMass7 分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(1S,2R)-1-benzyl-3-{(2-ethylbutyl)[(4-methoxyphenyl)sulfonyl]amino}-2-hydroxypropyl]carbamate, Protease, SULFATE ION 著者 Lockbaum, G.J, Schiffer, C.A. 登録日 2021-03-31 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.919 Å) 主引用文献 HIV-1 Protease (I84V) in Complex with UMass7 To Be Published
7MA9	HIV-1 Protease (I84V) in Complex with UMass9 分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(1S,2R)-3-[(1,3-benzodioxol-5-ylsulfonyl)(2-ethylbutyl)amino]-1-benzyl-2-hydroxypropyl}carbamate, Protease, SULFATE ION 著者 Lockbaum, G.J, Schiffer, C.A. 登録日 2021-03-31 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 HIV-1 Protease (I84V) in Complex with UMass9 To Be Published
7MAQ	Drug Resistant HIV-1 Protease (L10F, V32I, L33F, K45I, A71V, V82I, I84V) in Complex with DRV 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, Protease, SULFATE ION 著者 Lockbaum, G.J, Schiffer, C.A. 登録日 2021-03-31 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Drug Resistant HIV-1 Protease (L10F, V32I, L33F, K45I, A71V, V82I, I84V) in Complex with DRV To Be Published
7MA8	HIV-1 Protease (I84V) in Complex with UMass8 分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(1S,2R)-1-benzyl-3-[(2-ethylbutyl){[4-(hydroxymethyl)phenyl]sulfonyl}amino]-2-hydroxypropyl}carbamate, Protease, SULFATE ION 著者 Lockbaum, G.J, Schiffer, C.A. 登録日 2021-03-31 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.901 Å) 主引用文献 HIV-1 Protease (I84V) in Complex with UMass8 To Be Published
7MA3	HIV-1 Protease (I84V) in Complex with UMass2 分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(1S,2R)-1-benzyl-2-hydroxy-3-{[(4-methoxyphenyl)sulfonyl][(2S)-2-methylbutyl]amino}propyl]carbamate, Protease, SULFATE ION 著者 Lockbaum, G.J, Schiffer, C.A. 登録日 2021-03-31 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.969 Å) 主引用文献 HIV-1 Protease (I84V) in Complex with UMass2 To Be Published
7MA5	HIV-1 Protease (I84V) in Complex with UMass4 分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(1S,2R)-3-{(1,3-benzodioxol-5-ylsulfonyl)[(2S)-2-methylbutyl]amino}-1-benzyl-2-hydroxypropyl]carbamate, Protease, SULFATE ION 著者 Lockbaum, G.J, Schiffer, C.A. 登録日 2021-03-31 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.977 Å) 主引用文献 HIV-1 Protease (I84V) in Complex with UMass4 To Be Published
7MA4	HIV-1 Protease (I84V) in Complex with UMass3 分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(1S,2R)-1-benzyl-2-hydroxy-3-({[4-(hydroxymethyl)phenyl]sulfonyl}[(2S)-2-methylbutyl]amino)propyl]carbamate, Protease, SULFATE ION 著者 Lockbaum, G.J, Schiffer, C.A. 登録日 2021-03-31 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.989 Å) 主引用文献 HIV-1 Protease (I84V) in Complex with UMass3 To Be Published
7O2V	AURORA KINASE A IN COMPLEX WITH THE AUR-A/PDK1 INHIBITOR VI8 分子名称: 1-[[3,4-bis(fluoranyl)phenyl]methyl]-~{N}-[(1~{R})-2-[[(3~{E})-3-(1~{H}-imidazol-5-ylmethylidene)-2-oxidanylidene-1~{H}-indol-5-yl]amino]-2-oxidanylidene-1-phenyl-ethyl]-6-methyl-2-oxidanylidene-pyridine-3-carboxamide, Aurora kinase A 著者 Garau, G. 登録日 2021-03-31 公開日 2021-10-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Development of potent dual PDK1/AurA kinase inhibitors for cancer therapy: Lead-optimization, structural insights, and ADME-Tox profile. Eur.J.Med.Chem., 226, 2021
7O2O	Lysozyme structure from microfluidic-based in situ data collection 分子名称: 1,2-ETHANEDIOL, Lysozyme C, SODIUM ION 著者 Gardais, A, Chavas, L. 登録日 2021-03-31 公開日 2022-04-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.833 Å) 主引用文献 Manufacturing of Ultra-Thin X-ray-Compatible COC Microfluidic Devices for Optimal In Situ Macromolecular Crystallography Experiments. Micromachines (Basel), 13, 2022
7M8V	Human CYP11B2 in complex with LCI699 分子名称: 4-[(4R,5R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl]-3-fluorobenzonitrile, Cytochrome P450 11B2, mitochondrial, ... 著者 Scott, E.E, Brixius-Anderko, S. 登録日 2021-03-30 公開日 2021-06-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.08 Å) 主引用文献 Aldosterone Synthase Structure With Cushing Disease Drug LCI699 Highlights Avenues for Selective CYP11B Drug Design. Hypertension, 78, 2021
7M8W	XFEL crystal structure of the prostaglandin D2 receptor CRTH2 in complex with 15R-methyl-PGD2 分子名称: 15R-methyl-prostaglandin D2, CITRATE ANION, Prostaglandin D2 receptor 2, ... 著者 Shiriaeva, A, Han, G.W, Cherezov, V. 登録日 2021-03-30 公開日 2021-08-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Molecular basis for lipid recognition by the prostaglandin D 2 receptor CRTH2. Proc.Natl.Acad.Sci.USA, 118, 2021
7EIB	Cryo-EM structure of the type 1 bradykinin receptor in complex with the des-Arg10-kallidin and an Gq protein 分子名称: B1 bradykinin receptor, G subunit q (Gi1-Gq chimeric), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Yin, Y, Jiang, Y. 登録日 2021-03-30 公開日 2021-10-13 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular basis for kinin selectivity and activation of the human bradykinin receptors. Nat.Struct.Mol.Biol., 28, 2021
7EHX	X-ray crystal strcture of F46C/L49C sperm whale myoglobin with an intramolecular disulfide bond 分子名称: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE 著者 Lin, Y.W. 登録日 2021-03-30 公開日 2022-04-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 X-ray crystal strcture of F46C/L49C sperm whale myoglobin with an intramolecular disulfide bond To Be Published
7O24	Structure of the foamy viral protease-reverse transcriptase in complex with dsDNA. 分子名称: DNA (5'-D(*AP*AP*CP*AP*GP*AP*GP*TP*GP*CP*GP*AP*CP*AP*CP*CP*TP*GP*AP*TP*TP*CP*CP*A)-3'), DNA (5'-D(*TP*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*CP*TP*G)-3'), Pr125Pol 著者 Nowotny, M, Czarnocki-Cieciura, M. 登録日 2021-03-30 公開日 2021-06-30 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Structures of Substrate Complexes of Foamy Viral Protease-Reverse Transcriptase. J.Virol., 95, 2021
7O1U	X-ray structure of furin in complex with the guanylhydrazone-based inhibitor 1 (BEV241) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... 著者 Dahms, S.O, Brandstetter, H. 登録日 2021-03-30 公開日 2021-09-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 OFF-State-Specific Inhibition of the Proprotein Convertase Furin. Acs Chem.Biol., 16, 2021
7O22	X-ray structure of furin in complex with the guanylhydrazone-based inhibitor 4 (mi359) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... 著者 Dahms, S.O, Brandstetter, H. 登録日 2021-03-30 公開日 2021-09-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 OFF-State-Specific Inhibition of the Proprotein Convertase Furin. Acs Chem.Biol., 16, 2021
7O1Y	X-ray structure of furin in complex with the guanylhydrazone-based inhibitor 2 (mi307) soaked at 0.25 M NaCl 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... 著者 Dahms, S.O, Brandstetter, H. 登録日 2021-03-30 公開日 2021-09-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 OFF-State-Specific Inhibition of the Proprotein Convertase Furin. Acs Chem.Biol., 16, 2021
7O1W	X-ray structure of furin in complex with the guanylhydrazone-based inhibitor 2 (mi307) soaked at 1 M NaCl 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... 著者 Dahms, S.O, Brandstetter, H. 登録日 2021-03-30 公開日 2021-09-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 OFF-State-Specific Inhibition of the Proprotein Convertase Furin. Acs Chem.Biol., 16, 2021
7O20	X-ray structure of furin in complex with the guanylhydrazone-based inhibitor 3 (mi300) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... 著者 Dahms, S.O, Brandstetter, H. 登録日 2021-03-30 公開日 2021-09-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 OFF-State-Specific Inhibition of the Proprotein Convertase Furin. Acs Chem.Biol., 16, 2021
7M8I	Human CYP11B2 and human adrenodoxin in complex with fadrozole 分子名称: 4-[(5R)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl]benzonitrile, Adrenodoxin, Cytochrome P450 11B2, ... 著者 Scott, E.E, Brixius-Anderko, S. 登録日 2021-03-29 公開日 2021-05-26 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.94 Å) 主引用文献 Structural and functional insights into aldosterone synthase interaction with its redox partner protein adrenodoxin. J.Biol.Chem., 296, 2021
7EHL	Cryo-EM structure of human ABCB8 transporter in nucleotide binding state 分子名称: CHOLESTEROL, MAGNESIUM ION, Mitochondrial potassium channel ATP-binding subunit, ... 著者 Li, S.J, Yang, X, Shen, Y.Q. 登録日 2021-03-29 公開日 2021-05-05 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY 主引用文献 Cryo-EM structure of human ABCB8 transporter in nucleotide binding state. Biochem.Biophys.Res.Commun., 557, 2021
7O0Y	ABC transporter NosDFY, nucleotide-free in GDN 分子名称: MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... 著者 Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. 登録日 2021-03-28 公開日 2022-04-13 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
7O15	ABC transporter NosDFY, nucleotide-free in lipid nanodisc, R-domain 2 分子名称: MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... 著者 Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. 登録日 2021-03-28 公開日 2022-04-13 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY 主引用文献 Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
7O16	ABC transporter NosDFY, nucleotide-free in lipid nanodisc, R-domain 3 分子名称: MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... 著者 Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. 登録日 2021-03-28 公開日 2022-04-13 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY 主引用文献 Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
7O14	ABC transporter NosDFY, nucleotide-free in lipid nanodisc, R-domain 1 分子名称: MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... 著者 Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. 登録日 2021-03-28 公開日 2022-04-13 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY 主引用文献 Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022

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