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6VQN
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BU of 6vqn by Molmil
Co-crystal structure of human PD-L1 complexed with Compound A
分子名称: N,N'-(2,2'-dimethyl[1,1'-biphenyl]-3,3'-diyl)bis(5-{[(2-hydroxyethyl)amino]methyl}pyridine-2-carboxamide), Programmed cell death 1 ligand 1
著者White, A, Lakshminarasimhan, D, Leo, C, Suto, R.K.
登録日2020-02-05
公開日2021-01-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Checkpoint inhibition through small molecule-induced internalization of programmed death-ligand 1.
Nat Commun, 12, 2021
3DP6
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BU of 3dp6 by Molmil
Crystal structure of the binding domain of the AMPA subunit GluR2 bound to glutamate
分子名称: GLUTAMIC ACID, Glutamate receptor 2, ZINC ION
著者Ahmed, A.H, Wang, Q, Sondermann, H, Oswald, R.E.
登録日2008-07-07
公開日2008-11-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure of the S1S2 glutamate binding domain of GLuR3.
Proteins, 75, 2008
8E83
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BU of 8e83 by Molmil
Structure of 2-hydroxyisoflavanone synthase from Medicago truncatula
分子名称: Isoflavone synthase 1, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Pan, H, Wang, X.
登録日2022-08-25
公開日2022-11-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The protein conformational basis of isoflavone biosynthesis.
Commun Biol, 5, 2022
1H4J
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BU of 1h4j by Molmil
Methylobacterium extorquens methanol dehydrogenase D303E mutant
分子名称: CALCIUM ION, Methanol dehydrogenase [cytochrome c] subunit 1, Methanol dehydrogenase [cytochrome c] subunit 2, ...
著者Mohammed, F, Gill, R, Thompson, D, Cooper, J.B, Wood, S.P, Afolabi, P.R, Anthony, C.
登録日2001-05-11
公開日2001-08-23
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Site-Directed Mutagenesis and X-Ray Crystallography of the Pqq-Containing Quinoprotein Methanol Dehydrogenase and its Electron Acceptor, Cytochrome C(L)(,)
Biochemistry, 40, 2001
3HCM
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BU of 3hcm by Molmil
Crystal structure of human S100B in complex with S45
分子名称: (3R)-3-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]piperidine, ACETATE ION, CALCIUM ION, ...
著者Mangani, S, Cesari, L.
登録日2009-05-06
公開日2010-02-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Fragmenting the S100B-p53 Interaction: Combined Virtual/Biophysical Screening Approaches to Identify Ligands
Chemmedchem, 5, 2010
5M43
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BU of 5m43 by Molmil
Crystal structure of Yvh1 phosphatase domain from Chaetomium thermophilum
分子名称: GLYCEROL, NITRATE ION, Putative uncharacterized protein
著者Ahmed, Y.L, Sinning, I.
登録日2016-10-18
公開日2016-11-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.646 Å)
主引用文献Interaction network of the ribosome assembly machinery from a eukaryotic thermophile.
Protein Sci., 26, 2017
3AU9
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BU of 3au9 by Molmil
Crystal structure of the quaternary complex-1 of an isomerase
分子名称: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID, CALCIUM ION, ...
著者Umeda, T, Tanaka, N, Kusakabe, Y, Nakanishi, M, Kitade, Y, Nakamura, K.T.
登録日2011-02-01
公開日2011-08-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparum
Sci Rep, 1, 2011
5M3Q
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BU of 5m3q by Molmil
Crystal structure of Tif6 from Chaetomium thermophilum
分子名称: Eukaryotic translation initiation factor 6, GLYCEROL, SULFATE ION
著者Ahmed, Y.L, Calvino, F.R, Sinning, I.
登録日2016-10-17
公開日2016-11-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Interaction network of the ribosome assembly machinery from a eukaryotic thermophile.
Protein Sci., 26, 2017
3AU8
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BU of 3au8 by Molmil
Crystal structure of the ternary complex of an isomerase
分子名称: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, MANGANESE (II) ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Umeda, T, Tanaka, N, Kusakabe, Y, Nakanishi, M, Kitade, Y, Nakamura, K.T.
登録日2011-02-01
公開日2011-08-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Molecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparum
Sci Rep, 1, 2011
3DLN
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BU of 3dln by Molmil
Crystal structure of the binding domain of the AMPA subunit GluR3 bound to glutamate
分子名称: GLUTAMIC ACID, Glutamate receptor 3, ZINC ION
著者Ahmed, A.H, Wang, Q, Sondermann, H, Oswald, R.E.
登録日2008-06-27
公開日2008-11-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structure of the S1S2 glutamate binding domain of GLuR3.
Proteins, 75, 2008
3DP4
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BU of 3dp4 by Molmil
Crystal structure of the binding domain of the AMPA subunit GluR3 bound to AMPA
分子名称: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, Glutamate receptor 3, ZINC ION
著者Ahmed, A.H, Wang, Q, Sondermann, H, Oswald, R.E.
登録日2008-07-07
公開日2008-11-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structure of the S1S2 glutamate binding domain of GLuR3.
Proteins, 75, 2008
3AUA
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BU of 3aua by Molmil
Crystal structure of the quaternary complex-2 of an isomerase
分子名称: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 3-[ethanoyl(hydroxy)amino]propylphosphonic acid, CALCIUM ION, ...
著者Umeda, T, Tanaka, N, Kusakabe, Y, Nakanishi, M, Kitade, Y, Nakamura, K.T.
登録日2011-02-01
公開日2011-08-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Molecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparum
Sci Rep, 1, 2011
6OGM
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BU of 6ogm by Molmil
Crystal structure of apo unFused 4-OT
分子名称: 4-oxalocrotonate tautomerase, GLYCEROL
著者Medellin, B.P, Whitman, C.P, Zhang, Y.J.
登録日2019-04-03
公開日2020-02-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.865 Å)
主引用文献Structural, Kinetic, and Mechanistic Analysis of an Asymmetric 4-Oxalocrotonate Tautomerase Trimer.
Biochemistry, 58, 2019
7KPW
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BU of 7kpw by Molmil
Structure of the H-lobe of yeast CKM
分子名称: Mediator of RNA polymerase II transcription subunit 12
著者Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L.
登録日2020-11-12
公開日2021-01-27
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module.
Sci Adv, 7, 2021
2N0H
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BU of 2n0h by Molmil
NMR structure of Neuromedin C in presence of SDS micelles
分子名称: Neuromedin C (NMC)
著者Adrover, M, Sanchis, P, Vilanova, B, Pauwels, K, Martorell, G, Perez, J.
登録日2015-03-05
公開日2015-10-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Conformational ensembles of neuromedin C reveal a progressive coil-helix transition within a binding-induced folding mechanism.
RSC ADV, 5, 2015
6IQC
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BU of 6iqc by Molmil
Wild-type Programmed Cell Death 5 protein from Sulfolobus solfataricus
分子名称: DNA-binding protein SSO0352, SODIUM ION, TETRAETHYLENE GLYCOL
著者Chen, C.Y, Lin, K.F, Hsu, C.Y, Tsai, M.J.
登録日2018-11-06
公開日2019-02-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Crystal structure of the programmed cell death 5 protein from Sulfolobus solfataricus.
Acta Crystallogr F Struct Biol Commun, 75, 2019
6IQO
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BU of 6iqo by Molmil
Se-Met L45M Programmed Cell Death 5 protein from Sulfolobus solfataricus
分子名称: DNA-binding protein SSO0352, NONAETHYLENE GLYCOL
著者Chen, C.Y, Lin, K.F, Hsu, C.Y, Tsai, M.J.
登録日2018-11-08
公開日2019-02-20
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Crystal structure of the programmed cell death 5 protein from Sulfolobus solfataricus.
Acta Crystallogr F Struct Biol Commun, 75, 2019
6JP7
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BU of 6jp7 by Molmil
Human antibody 32D6 Fab in complex with PEG
分子名称: (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, HEXAETHYLENE GLYCOL, immunoglobulin Fab heavy chain, ...
著者Lee, C.C, Ko, T.P, Lin, L.L, Wang, A.H.J.
登録日2019-03-26
公開日2020-02-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.909 Å)
主引用文献Structural basis of polyethylene glycol recognition by antibody.
J.Biomed.Sci., 27, 2020
6VMT
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BU of 6vmt by Molmil
Leishmania major Programmed Cell Death Protein 5 Homolog
分子名称: Programmed Cell Death Protein 5 Homolog
著者Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2020-01-28
公開日2020-02-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Leishmania major Programmed Cell Death Protein 5 Homolog
To be published
6JU0
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BU of 6ju0 by Molmil
Mouse antibody 3.3 Fab in complex with PEG
分子名称: 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, Fab heavy chain, ...
著者Lee, C.C, Ko, T.P, Lin, L.L, Wang, A.H.J.
登録日2019-04-12
公開日2020-02-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Structural basis of polyethylene glycol recognition by antibody.
J.Biomed.Sci., 27, 2020
5ZPW
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BU of 5zpw by Molmil
Generation of a long-acting fusion inhibitor against HIV-1
分子名称: MET-THR-TRP-GLU-GLU-TRP-ASP-MK8-LYS-ILE-GLU-MK8-TYR-THR-MK8-LYS-ILE-GLU-MK8-LEU-ILE-LYS-LYS-SER, Transmembrane protein gp41
著者Guo, Y, Shi, X.L.
登録日2018-04-16
公開日2019-03-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献Generation of a long-acting fusion inhibitor against HIV-1.
Medchemcomm, 9, 2018
5O9B
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BU of 5o9b by Molmil
Solution NMR structure of human GATA2 C-terminal zinc finger domain
分子名称: Endothelial transcription factor GATA-2, ZINC ION
著者Nurmohamed, S.S, Broadhurst, R.W, May, G, Enver, T.
登録日2017-06-16
公開日2019-02-06
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Solution NMR structure of human GATA2 C-terminal zinc finger domain
To Be Published
6JWC
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BU of 6jwc by Molmil
Mouse antibody 2B5 Fab in complex with PEG
分子名称: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, DI(HYDROXYETHYL)ETHER, DODECAETHYLENE GLYCOL, ...
著者Lee, C.C, Ko, T.P, Su, Y.C, Lin, L.L, Roffler, S.R, Wang, A.H.J.
登録日2019-04-19
公開日2020-02-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.297 Å)
主引用文献Structural basis of polyethylene glycol recognition by antibody.
J.Biomed.Sci., 27, 2020
6ZFV
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BU of 6zfv by Molmil
Solution NMR structure of human GATA2 N-terminal zinc finger domain
分子名称: Endothelial transcription factor GATA-2, ZINC ION
著者Nurmohamed, S.S, Broadhurst, R.W, May, G, Enver, T.
登録日2020-06-18
公開日2021-06-30
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Solution NMR structure of human GATA2 C-terminal zinc finger domain
To Be Published
7NFY
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BU of 7nfy by Molmil
P1a-state of wild type human mitochondrial LONP1 protease with bound substrate protein and ATPgS
分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial, ...
著者Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P.
登録日2021-02-08
公開日2021-02-24
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022

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件を2024-08-14に公開中

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