3AU9

Crystal structure of the quaternary complex-1 of an isomerase

Summary for 3AU9

• Entry DOI: 10.2210/pdb3au9/pdb
• Related: 3AU8 3AUA
• Descriptor: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: nadph binding, isomerase-isomerase inhibitor complex, isomerase/isomerase inhibitor
• Biological source: Plasmodium falciparum
• Cellular location: Plastid, apicoplast: O96693
• Total number of polymer chains: 2
• Total formula weight: 113645.03

Authors

Umeda, T.,Tanaka, N.,Kusakabe, Y.,Nakanishi, M.,Kitade, Y.,Nakamura, K.T. (deposition date: 2011-02-01, release date: 2011-08-10, Last modification date: 2024-03-13)

• Primary citation: Umeda, T.,Tanaka, N.,Kusakabe, Y.,Nakanishi, M.,Kitade, Y.,Nakamura, K.T.; Molecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparum; Sci Rep, 1:9-9, 2011; PubMed: 22355528; DOI: 10.1038/srep00009

Experimental method

X-RAY DIFFRACTION (1.9 Å)