4TWP
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![BU of 4twp by Molmil](/molmil-images/mine/4twp) | The crystal structure of human abl1 T315I gatekeeper mutant kinase domain in complex with axitinib | 分子名称: | AXITINIB, NICKEL (II) ION, SODIUM ION, ... | 著者 | Johnson, E, McTigue, M, Cronin, C.N. | 登録日 | 2014-07-01 | 公開日 | 2015-02-11 | 最終更新日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation. Nature, 519, 2015
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4U0R
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![BU of 4u0r by Molmil](/molmil-images/mine/4u0r) | Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to monoclonal antibody 9AD4 | 分子名称: | Monoclonal antibody 9AD4 heavy chain, Monoclonal antibody 9AD4 light chain, Reticulocyte binding protein 5 | 著者 | Wright, K.E, Hjerrild, K.A, Bartlett, J, Douglas, A.D, Jin, J, Brown, R.E, Ashfield, R, Clemmensen, S.B, de Jongh, W.A, Draper, S.J, Higgins, M.K. | 登録日 | 2014-07-14 | 公開日 | 2014-08-13 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies. Nature, 515, 2014
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2GFY
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![BU of 2gfy by Molmil](/molmil-images/mine/2gfy) | |
2GFV
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![BU of 2gfv by Molmil](/molmil-images/mine/2gfv) | |
2G9K
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![BU of 2g9k by Molmil](/molmil-images/mine/2g9k) | Human Transthyretin (TTR) Complexed with Hydroxylated polychlorinated Biphenyl-4-hydroxy-2',3,3',4',5-Pentachlorobiphenyl | 分子名称: | 2',3,3',4',5-PENTACHLOROBIPHENYL-4-OL, Transthyretin | 著者 | Palaninathan, S.K, Smith, C, Safe, S.H, Kelly, J.W, Sacchettini, J.C. | 登録日 | 2006-03-06 | 公開日 | 2006-03-14 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Hydroxylated polychlorinated biphenyls selectively bind transthyretin in blood and inhibit amyloidogenesis: rationalizing rodent PCB toxicity Chem.Biol., 11, 2004
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2JVV
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![BU of 2jvv by Molmil](/molmil-images/mine/2jvv) | |
2JUE
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![BU of 2jue by Molmil](/molmil-images/mine/2jue) | |
2LNU
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![BU of 2lnu by Molmil](/molmil-images/mine/2lnu) | Solution NMR Structure of the uncharacterized protein from gene locus rrnAC0354 of Haloarcula marismortui, Northeast Structural Genomics Consortium Target HmR11 | 分子名称: | Uncharacterized protein | 著者 | Rossi, P, Liu, G, Lange, O.F, Lee, H, Janjua, H, Ciccosanti, C, Wang, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2012-01-05 | 公開日 | 2012-01-18 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples. Proc.Natl.Acad.Sci.USA, 109, 2012
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2L1A
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![BU of 2l1a by Molmil](/molmil-images/mine/2l1a) | Solution NMR structure of the N-terminal GTPase-like domain of dictyostelium discoideum Fomin C | 分子名称: | Formin-C | 著者 | Dames, S.A, Schoenichen, A, Stephan, G, Geyer, M. | 登録日 | 2010-07-27 | 公開日 | 2011-08-17 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure, dynamics, lipid binding, and physiological relevance of the putative GTPase-binding domain of Dictyostelium formin C. J.Biol.Chem., 286, 2011
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2LOK
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![BU of 2lok by Molmil](/molmil-images/mine/2lok) | Solution NMR Structure of the uncharacterized protein from gene locus VNG_0733H of Halobacterium salinarium, Northeast Structural Genomics Consortium Target HsR50 | 分子名称: | Uncharacterized protein | 著者 | Rossi, P, Lange, O.F, Lee, H, Hamilton, K, Ciccosanti, C, Buchwald, W.A, Wang, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2012-01-24 | 公開日 | 2012-02-01 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples. Proc.Natl.Acad.Sci.USA, 109, 2012
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2KZN
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![BU of 2kzn by Molmil](/molmil-images/mine/2kzn) | Solution NMR Structure of Peptide methionine sulfoxide reductase msrB from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR10 | 分子名称: | Peptide methionine sulfoxide reductase msrB | 著者 | Ertekin, A, Maglaqui, M, Janjua, H, Cooper, B, Ciccosanti, C, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Prestegard, J, Lee, H, Aramini, J.M, Rossi, P, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2010-06-18 | 公開日 | 2010-07-07 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples. Proc.Natl.Acad.Sci.USA, 109, 2012
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2LCB
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![BU of 2lcb by Molmil](/molmil-images/mine/2lcb) | Solution Structure of a Minor and Transiently Formed State of a T4 Lysozyme Mutant | 分子名称: | Lysozyme | 著者 | Bouvignies, G, Vallurupalli, P, Hansen, D, Correia, B, Lange, O, Bah, A, Vernon, R.M, Dahlquist, F.W, Baker, D, Kay, L.E. | 登録日 | 2011-04-26 | 公開日 | 2011-08-17 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a minor and transiently formed state of a T4 lysozyme mutant. Nature, 477, 2011
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2LLE
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![BU of 2lle by Molmil](/molmil-images/mine/2lle) | Computational design of an eight-stranded (beta/alpha)-barrel from fragments of different folds | 分子名称: | Chemotaxis protein CheY, Imidazole glycerol phosphate synthase subunit HisF chimera | 著者 | Coles, M, Truffault, V, Eisenbeis, S, Proffitt, W, Meiler, J, Hocker, B. | 登録日 | 2011-11-07 | 公開日 | 2012-03-21 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Potential of fragment recombination for rational design of proteins. J.Am.Chem.Soc., 134, 2012
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2LEP
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2LC9
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![BU of 2lc9 by Molmil](/molmil-images/mine/2lc9) | Solution Structure of a Minor and Transiently Formed State of a T4 Lysozyme Mutant | 分子名称: | Lysozyme | 著者 | Bouvignies, G, Vallurupalli, P, Hansen, D, Correia, B, Lange, O, Bah, A, Vernon, R.M, Dahlquist, F.W, Baker, D, Kay, L.E. | 登録日 | 2011-04-26 | 公開日 | 2011-08-17 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a minor and transiently formed state of a T4 lysozyme mutant. Nature, 477, 2011
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2LJE
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2LN4
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2LMD
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![BU of 2lmd by Molmil](/molmil-images/mine/2lmd) | Minimal Constraints Solution NMR Structure of Prospero Homeobox protein 1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4660B | 分子名称: | Prospero homeobox protein 1 | 著者 | Rossi, P, Lange, O.A, Lee, H, Maglaqui, M, Janjua, H, Ciccosanti, C, Zhao, L, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2011-11-29 | 公開日 | 2011-12-21 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples. Proc.Natl.Acad.Sci.USA, 109, 2012
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5AFD
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![BU of 5afd by Molmil](/molmil-images/mine/5afd) | Native structure of N-acetylneuramininate lyase (sialic acid aldolase) from Aliivibrio salmonicida | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, N-ACETYLNEURAMINATE LYASE | 著者 | Gurung, M.K, Altermark, B, Rader, I.L.U, Helland, R, Smalas, A.O. | 登録日 | 2015-01-21 | 公開日 | 2016-03-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Features and structure of a cold active N-acetylneuraminate lyase. Plos One, 14, 2019
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3UL3
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![BU of 3ul3 by Molmil](/molmil-images/mine/3ul3) | |
5A5Z
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![BU of 5a5z by Molmil](/molmil-images/mine/5a5z) | Approved Drugs Containing Thiols as Inhibitors of Metallo-beta- lactamases: Strategy To Combat Multidrug-Resistant Bacteria | 分子名称: | BETA-LACTAMASE NDM-1, TIOPRONIN, ZINC ION | 著者 | Klingler, F.M, Wichelhaus, T.A, Frank, D, Cuesta-Bernal, J, El-Delik, J, Mueller, H.F, Sjuts, H, Goettig, S, Koenigs, A, Pogoryelov, D, Proschak, E. | 登録日 | 2015-06-23 | 公開日 | 2015-07-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Approved Drugs Containing Thiols as Inhibitors of Metallo-beta-lactamases: Strategy To Combat Multidrug-Resistant Bacteria. J. Med. Chem., 58, 2015
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5AD8
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![BU of 5ad8 by Molmil](/molmil-images/mine/5ad8) | Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-((3-Aminomethyl)phenoxy)methyl)quinolin-2-amine | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, 7-[[3-(aminomethyl)phenoxy]methyl]quinolin-2-amine, ACETATE ION, ... | 著者 | Li, H, Poulos, T.L. | 登録日 | 2015-08-20 | 公開日 | 2015-10-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.905 Å) | 主引用文献 | Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase. J.Med.Chem., 58, 2015
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5ADA
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![BU of 5ada by Molmil](/molmil-images/mine/5ada) | Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-(((3-((Dimethylamino)methyl)phenyl)amino)methyl) quinolin-2-amine | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, 7-[[[3-[(dimethylamino)methyl]phenyl]amino]methyl]quinolin-2-amine, ACETATE ION, ... | 著者 | Li, H, Poulos, T.L. | 登録日 | 2015-08-20 | 公開日 | 2015-10-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase. J.Med.Chem., 58, 2015
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5ADB
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![BU of 5adb by Molmil](/molmil-images/mine/5adb) | Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-((4-Chloro-3-((methylamino)methyl)phenoxy)methyl) quinolin-2-amine | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, 7-[[4-chloranyl-3-(methylaminomethyl)phenoxy]methyl]quinolin-2-amine, ACETATE ION, ... | 著者 | Li, H, Poulos, T.L. | 登録日 | 2015-08-20 | 公開日 | 2015-10-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase. J.Med.Chem., 58, 2015
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5AD6
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![BU of 5ad6 by Molmil](/molmil-images/mine/5ad6) | Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-((3-(Dimethylamino)methyl)phenoxy)methyl)quinolin-2- amine | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, 7-[[3-[(dimethylamino)methyl]phenoxy]methyl]quinolin-2-amine, ACETATE ION, ... | 著者 | Li, H, Poulos, T.L. | 登録日 | 2015-08-20 | 公開日 | 2015-10-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.005 Å) | 主引用文献 | Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase. J.Med.Chem., 58, 2015
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