PDB: 17091 件ウェブページステータス検索Chemie searchBIRD

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4TWP	The crystal structure of human abl1 T315I gatekeeper mutant kinase domain in complex with axitinib 分子名称: AXITINIB, NICKEL (II) ION, SODIUM ION, ... 著者 Johnson, E, McTigue, M, Cronin, C.N. 登録日 2014-07-01 公開日 2015-02-11 最終更新日 2024-08-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation. Nature, 519, 2015
4U0R	Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to monoclonal antibody 9AD4 分子名称: Monoclonal antibody 9AD4 heavy chain, Monoclonal antibody 9AD4 light chain, Reticulocyte binding protein 5 著者 Wright, K.E, Hjerrild, K.A, Bartlett, J, Douglas, A.D, Jin, J, Brown, R.E, Ashfield, R, Clemmensen, S.B, de Jongh, W.A, Draper, S.J, Higgins, M.K. 登録日 2014-07-14 公開日 2014-08-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies. Nature, 515, 2014
2GFY	Structure of E. coli FabF(K335A) mutant with covalently linked dodecanoic acid 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, LAURIC ACID 著者 Soisson, S.M, Parthasarathy, G. 登録日 2006-03-23 公開日 2006-05-23 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Platensimycin is a selective FabF inhibitor with potent antibiotic properties. Nature, 441, 2006
2GFV	Structure of E. coli FabF (KASII) C163Q mutant 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2 著者 Soisson, S.M, Parthasarathy, G. 登録日 2006-03-23 公開日 2006-05-23 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Platensimycin is a selective FabF inhibitor with potent antibiotic properties. Nature, 441, 2006
2G9K	Human Transthyretin (TTR) Complexed with Hydroxylated polychlorinated Biphenyl-4-hydroxy-2',3,3',4',5-Pentachlorobiphenyl 分子名称: 2',3,3',4',5-PENTACHLOROBIPHENYL-4-OL, Transthyretin 著者 Palaninathan, S.K, Smith, C, Safe, S.H, Kelly, J.W, Sacchettini, J.C. 登録日 2006-03-06 公開日 2006-03-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Hydroxylated polychlorinated biphenyls selectively bind transthyretin in blood and inhibit amyloidogenesis: rationalizing rodent PCB toxicity Chem.Biol., 11, 2004
2JVV	Solution Structure of E. coli NusG carboxyterminal domain 分子名称: Transcription antitermination protein nusG 著者 Schweimer, K, Scheckenhofer, U, Roesch, P. 登録日 2007-09-26 公開日 2008-10-14 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Two structurally independent domains of E. coli NusG create regulatory plasticity via distinct interactions with RNA polymerase and regulators. J.Mol.Biol., 391, 2009
2JUE	Solution structure of the all-D kalata B1 分子名称: Kalata-B1 著者 Daly, N.L, Sando, L, Craik, D. 登録日 2007-08-23 公開日 2008-08-05 最終更新日 2020-08-12 実験手法 SOLUTION NMR 主引用文献 A Synthetic mirror image of kalata B1 reveals that cyclotide activity is independent of a protein receptor. Chembiochem, 12, 2011
2LNU	Solution NMR Structure of the uncharacterized protein from gene locus rrnAC0354 of Haloarcula marismortui, Northeast Structural Genomics Consortium Target HmR11 分子名称: Uncharacterized protein 著者 Rossi, P, Liu, G, Lange, O.F, Lee, H, Janjua, H, Ciccosanti, C, Wang, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2012-01-05 公開日 2012-01-18 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples. Proc.Natl.Acad.Sci.USA, 109, 2012
2L1A	Solution NMR structure of the N-terminal GTPase-like domain of dictyostelium discoideum Fomin C 分子名称: Formin-C 著者 Dames, S.A, Schoenichen, A, Stephan, G, Geyer, M. 登録日 2010-07-27 公開日 2011-08-17 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structure, dynamics, lipid binding, and physiological relevance of the putative GTPase-binding domain of Dictyostelium formin C. J.Biol.Chem., 286, 2011
2LOK	Solution NMR Structure of the uncharacterized protein from gene locus VNG_0733H of Halobacterium salinarium, Northeast Structural Genomics Consortium Target HsR50 分子名称: Uncharacterized protein 著者 Rossi, P, Lange, O.F, Lee, H, Hamilton, K, Ciccosanti, C, Buchwald, W.A, Wang, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2012-01-24 公開日 2012-02-01 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples. Proc.Natl.Acad.Sci.USA, 109, 2012
2KZN	Solution NMR Structure of Peptide methionine sulfoxide reductase msrB from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR10 分子名称: Peptide methionine sulfoxide reductase msrB 著者 Ertekin, A, Maglaqui, M, Janjua, H, Cooper, B, Ciccosanti, C, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Prestegard, J, Lee, H, Aramini, J.M, Rossi, P, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2010-06-18 公開日 2010-07-07 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples. Proc.Natl.Acad.Sci.USA, 109, 2012
2LCB	Solution Structure of a Minor and Transiently Formed State of a T4 Lysozyme Mutant 分子名称: Lysozyme 著者 Bouvignies, G, Vallurupalli, P, Hansen, D, Correia, B, Lange, O, Bah, A, Vernon, R.M, Dahlquist, F.W, Baker, D, Kay, L.E. 登録日 2011-04-26 公開日 2011-08-17 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of a minor and transiently formed state of a T4 lysozyme mutant. Nature, 477, 2011
2LLE	Computational design of an eight-stranded (beta/alpha)-barrel from fragments of different folds 分子名称: Chemotaxis protein CheY, Imidazole glycerol phosphate synthase subunit HisF chimera 著者 Coles, M, Truffault, V, Eisenbeis, S, Proffitt, W, Meiler, J, Hocker, B. 登録日 2011-11-07 公開日 2012-03-21 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Potential of fragment recombination for rational design of proteins. J.Am.Chem.Soc., 134, 2012
2LEP	Solution Structure of N-terminal Cytosolic Domain of Rhomboid Intramembrane Protease from Escherichia Coli 分子名称: Rhomboid protease glpG 1 著者 Sherratt, A.R, Ghasriani, H, Goto, N.K. 登録日 2011-06-20 公開日 2012-06-20 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Activity-Based Protein Profiling of the Escherichia coli GlpG Rhomboid Protein Delineates the Catalytic Core. Biochemistry, 51, 2012
2LC9	Solution Structure of a Minor and Transiently Formed State of a T4 Lysozyme Mutant 分子名称: Lysozyme 著者 Bouvignies, G, Vallurupalli, P, Hansen, D, Correia, B, Lange, O, Bah, A, Vernon, R.M, Dahlquist, F.W, Baker, D, Kay, L.E. 登録日 2011-04-26 公開日 2011-08-17 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of a minor and transiently formed state of a T4 lysozyme mutant. Nature, 477, 2011
2LJE	Biphosphorylated (747pY, 759pY) beta3 integrin cytoplasmic tail under membrane mimetic conditions 分子名称: Integrin beta-3 著者 Deshmukh, L, Vinogradova, O. 登録日 2011-09-11 公開日 2011-10-05 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Tyrosine phosphorylation as a conformational switch: a case study of integrin Beta3 cytoplasmic tail. J.Biol.Chem., 286, 2011
2LN4	Insight into the antimicrobial activities based on the Structure-activity relationships of coprisin isolated from the Dung Beetle, Copris tripartitus 分子名称: Coprisin 著者 Kim, Y, Kim, J.K, Lee, E. 登録日 2011-12-16 公開日 2012-11-28 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Insight into the antimicrobial activities of coprisin isolated from the dung beetle, Copris tripartitus, revealed by structure-activity relationships Biochim.Biophys.Acta, 2012
2LMD	Minimal Constraints Solution NMR Structure of Prospero Homeobox protein 1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4660B 分子名称: Prospero homeobox protein 1 著者 Rossi, P, Lange, O.A, Lee, H, Maglaqui, M, Janjua, H, Ciccosanti, C, Zhao, L, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2011-11-29 公開日 2011-12-21 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples. Proc.Natl.Acad.Sci.USA, 109, 2012
5AFD	Native structure of N-acetylneuramininate lyase (sialic acid aldolase) from Aliivibrio salmonicida 分子名称: 1,2-ETHANEDIOL, GLYCEROL, N-ACETYLNEURAMINATE LYASE 著者 Gurung, M.K, Altermark, B, Rader, I.L.U, Helland, R, Smalas, A.O. 登録日 2015-01-21 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Features and structure of a cold active N-acetylneuraminate lyase. Plos One, 14, 2019
3UL3	Structural insights into thioredoxin-2: a component of malaria parasite protein secretion machinery 分子名称: Thioredoxin 著者 Sharma, A, Sharma, A, Dixit, S, Sharma, A. 登録日 2011-11-10 公開日 2011-12-14 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.905 Å) 主引用文献 Structural insights into thioredoxin-2: a component of malaria parasite protein secretion machinery. Sci Rep, 1, 2011
5A5Z	Approved Drugs Containing Thiols as Inhibitors of Metallo-beta- lactamases: Strategy To Combat Multidrug-Resistant Bacteria 分子名称: BETA-LACTAMASE NDM-1, TIOPRONIN, ZINC ION 著者 Klingler, F.M, Wichelhaus, T.A, Frank, D, Cuesta-Bernal, J, El-Delik, J, Mueller, H.F, Sjuts, H, Goettig, S, Koenigs, A, Pogoryelov, D, Proschak, E. 登録日 2015-06-23 公開日 2015-07-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Approved Drugs Containing Thiols as Inhibitors of Metallo-beta-lactamases: Strategy To Combat Multidrug-Resistant Bacteria. J. Med. Chem., 58, 2015
5AD8	Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-((3-Aminomethyl)phenoxy)methyl)quinolin-2-amine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 7-[[3-(aminomethyl)phenoxy]methyl]quinolin-2-amine, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2015-08-20 公開日 2015-10-28 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.905 Å) 主引用文献 Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase. J.Med.Chem., 58, 2015
5ADA	Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-(((3-((Dimethylamino)methyl)phenyl)amino)methyl) quinolin-2-amine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 7-[[[3-[(dimethylamino)methyl]phenyl]amino]methyl]quinolin-2-amine, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2015-08-20 公開日 2015-10-28 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase. J.Med.Chem., 58, 2015
5ADB	Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-((4-Chloro-3-((methylamino)methyl)phenoxy)methyl) quinolin-2-amine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 7-[[4-chloranyl-3-(methylaminomethyl)phenoxy]methyl]quinolin-2-amine, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2015-08-20 公開日 2015-10-28 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase. J.Med.Chem., 58, 2015
5AD6	Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-((3-(Dimethylamino)methyl)phenoxy)methyl)quinolin-2- amine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 7-[[3-[(dimethylamino)methyl]phenoxy]methyl]quinolin-2-amine, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2015-08-20 公開日 2015-10-28 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.005 Å) 主引用文献 Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase. J.Med.Chem., 58, 2015

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