PDB: 10140 件ウェブページステータス検索Chemie searchBIRD

---

4OM1	Crystal structure of antibody VRC07-I30Q, G54W, S58N in complex with clade A/E 93TH057 HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... 著者 Kwon, Y.D, Kwong, P.D. 登録日 2014-01-25 公開日 2014-09-03 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.131 Å) 主引用文献 Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
4OLX	Crystal structure of antibody VRC07-G54L in complex with clade A/E 93TH057 HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... 著者 Kwon, Y.D, Kwong, P.D. 登録日 2014-01-25 公開日 2014-09-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
5FV1	Crystal structure of hVEGF in complex with VK domain antibody 分子名称: VASCULAR ENDOTHELIAL GROWTH FACTOR A, VK DOMAIN ANTIBODY 著者 Chung, C, Walker, A. 登録日 2016-02-02 公開日 2016-02-17 最終更新日 2019-05-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Novel Interaction Mechanism of a Domain Antibody Based Inhibitor of Human Vascular Endothelial Growth Factor with Greater Potency Than Ranibizumab and Bevacizumab and Improved Capacity Over Aflibercept. J.Biol.Chem., 291, 2016
6BA5	Potent and Selective Antitumor Activity of a T-Cell Engaging Bispecific Antibody Targeting a Membrane-Proximal Epitope of ROR1 分子名称: Inactive tyrosine-protein kinase transmembrane receptor ROR1, Variable domain Heavy chain, antibody R11, ... 著者 Park, H, Rader, C. 登録日 2017-10-12 公開日 2018-06-13 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4OLZ	Crystal structure of antibody VRC07-G54W in complex with clade A/E 93TH057 HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... 著者 Kwon, Y.D, Kwong, P.D. 登録日 2014-01-25 公開日 2014-09-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
8HRH	SN-131/1B2 anti-MUC1 antibody with a glycopeptide 分子名称: 1-ACETYL-L-PROLINE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ALANINE, ... 著者 Wakui, H, Horidome, C, Yao, M, Ose, T, Nishimura, S.-I. 登録日 2022-12-15 公開日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Structural and molecular insight into antibody recognition of dynamic neoepitopes in membrane tethered MUC1 of pancreatic cancer cells and secreted exosomes. Rsc Chem Biol, 4, 2023
1A5F	FAB FRAGMENT OF A MONOCLONAL ANTI-E-SELECTIN ANTIBODY 分子名称: MONOCLONAL ANTI-E-SELECTIN 7A9 ANTIBODY (HEAVY CHAIN), MONOCLONAL ANTI-E-SELECTIN 7A9 ANTIBODY (LIGHT CHAIN) 著者 Rodriguez-Romero, A, Almog, O, Tordova, M, Randhawa, Z. 登録日 1998-02-16 公開日 1999-04-20 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Primary and tertiary structures of the Fab fragment of a monoclonal anti-E-selectin 7A9 antibody that inhibits neutrophil attachment to endothelial cells. J.Biol.Chem., 273, 1998
5FV2	Crystal structure of hVEGF in complex with VH domain antibody 分子名称: VASCULAR ENDOTHELIAL GROWTH FACTOR, VH DOMAIN ANTIBODY 著者 Chung, C, Batuwangala, T. 登録日 2016-02-02 公開日 2016-02-17 最終更新日 2019-05-15 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Novel Interaction Mechanism of a Domain Antibody Based Inhibitor of Human Vascular Endothelial Growth Factor with Greater Potency Than Ranibizumab and Bevacizumab and Improved Capacity Over Aflibercept. J.Biol.Chem., 291, 2016
1QOK	MFE-23 AN ANTI-CARCINOEMBRYONIC ANTIGEN SINGLE-CHAIN FV ANTIBODY 分子名称: MFE-23 RECOMBINANT ANTIBODY FRAGMENT 著者 Boehm, M.K, Corper, A.L, Wan, T, Sohi, M.K, Sutton, B.J, Thornton, J.D, Keep, P.A, Chester, K.A, Begent, R.H.J, Perkins, S.J. 登録日 1999-11-11 公開日 2000-11-10 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of the Anti-Carcinoembryonic Antigen Single-Chain Fv Antibody Mfe-23 and a Model for Antigen Binding Based on Intermolecular Contacts Biochem.J., 346, 2000
4Z0B	Crystal Structure of the Fab Fragment of Anti-ofloxacin Antibody and Exploration Its Receptor Binding Site 分子名称: PHOSPHATE ION, antibody heavy chain, antibody light chain 著者 He, K, Du, X, Sheng, W, Zhou, X, Wang, J, Wang, S. 登録日 2015-03-26 公開日 2016-04-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal Structure of the Fab Fragment of an Anti-ofloxacin Antibody and Exploration of Its Specific Binding. J.Agric.Food Chem., 64, 2016
6AZZ	Crystal structure of Pfs25 in complex with the transmission blocking antibody 1190 分子名称: 1190 antibody, heavy chain, light chain, ... 著者 Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P. 登録日 2017-09-13 公開日 2017-11-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun, 8, 2017
6B0E	Crystal structure of Pfs25 in complex with the transmission blocking antibody 1260 分子名称: 1260 antibody, heavy chain, light chain, ... 著者 Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P. 登録日 2017-09-14 公開日 2017-11-15 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun, 8, 2017
4GXU	Crystal structure of antibody 1F1 bound to the 1918 influenza hemagglutinin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 1F1, heavy chain, ... 著者 Ekiert, D.C, Wilson, I.A. 登録日 2012-09-04 公開日 2012-12-19 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.294 Å) 主引用文献 Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses. Plos Pathog., 8, 2012
1RZK	HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ... 著者 Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. 登録日 2003-12-24 公開日 2004-02-03 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA, 101, 2004
1RZJ	HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ... 著者 Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. 登録日 2003-12-24 公開日 2004-02-03 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA, 101, 2004
6B0G	Crystal structure of Pfs25 in complex with the transmission blocking antibody 1245 分子名称: 1245 Antibody, Heavy Chain, Light Chain, ... 著者 McLeod, B, Scally, S.W, Bosch, A, King, C.R, Julien, J.P. 登録日 2017-09-14 公開日 2017-11-08 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun, 8, 2017
3H42	Crystal structure of PCSK9 in complex with Fab from LDLR competitive antibody 分子名称: Fab from LDLR competitive antibody: Heavy chain, Fab from LDLR competitive antibody: Light chain, Proprotein convertase subtilisin/kexin type 9, ... 著者 Piper, D.E, Walker, N.P.C, Romanow, W.G, Thibault, S.T, Tsai, M.M, Yang, E. 登録日 2009-04-17 公開日 2009-05-05 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 From the Cover: A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates. Proc.Natl.Acad.Sci.USA, 106, 2009
6B08	Crystal structure of Pfs25 in complex with the transmission blocking antibody 1276 分子名称: 1276 antibody, heavy chain, light chain, ... 著者 Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P. 登録日 2017-09-14 公開日 2017-11-15 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun, 8, 2017
6B0A	Crystal structure of Pfs25 in complex with the transmission blocking antibody 1269 分子名称: 1269 antibody, heavy chain, light chain, ... 著者 Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P. 登録日 2017-09-14 公開日 2017-11-15 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun, 8, 2017
4K3E	Crystal structure of bovine antibody BLV5B8 with ultralong CDR H3 分子名称: BOVINE ANTIBODY WITH ULTRALONG CDR H3, HEAVY CHAIN, LIGHT CHAIN, ... 著者 Ekiert, D.C, Wang, F, Wilson, I.A. 登録日 2013-04-10 公開日 2013-06-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Reshaping antibody diversity. Cell(Cambridge,Mass.), 153, 2013
6PHF	Pfs25 in complex with the human transmission blocking antibody 2587 分子名称: 25 kDa ookinete surface antigen, 2587 Antibody Fab, Heavy Chain, ... 著者 McLeod, B.R, Julien, J.P. 登録日 2019-06-25 公開日 2019-10-02 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25. Nat Commun, 10, 2019
6PHH	Unliganded human transmission blocking antibody 2544 分子名称: 2544 Antibody Fab, Heavy Chain, Light Chain, ... 著者 McLeod, B.R, Julien, J.P. 登録日 2019-06-25 公開日 2019-10-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25. Nat Commun, 10, 2019
6PHC	Pfs25 in complex with the human transmission blocking antibody 2544 分子名称: 25 kDa ookinete surface antigen, 2544 Antibody Fab, Heavy Chain, ... 著者 McLeod, B.R, Julien, J.P. 登録日 2019-06-25 公開日 2019-10-02 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25. Nat Commun, 10, 2019
6PHB	Pfs25 in complex with the human transmission blocking antibody 2530 分子名称: 1,2-ETHANEDIOL, 25 kDa ookinete surface antigen, 2530 Antibody Fab, ... 著者 McLeod, B.R, Julien, J.P. 登録日 2019-06-25 公開日 2019-10-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25. Nat Commun, 10, 2019
6PHG	Predicted germline variant of human transmission blocking antibody 2544 分子名称: GLYCEROL, Germline 2544 Antibody Fab, Heavy Chain, ... 著者 McLeod, B.R, Julien, J.P. 登録日 2019-06-25 公開日 2019-10-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25. Nat Commun, 10, 2019

<20212223242526272829303132333435>