PDB: 183105 件ウェブページステータス検索Chemie searchBIRD

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4O3U	Zymogen HGF-beta/MET with Zymogen Activator Peptide ZAP2.3 分子名称: Hepatocyte growth factor, Hepatocyte growth factor receptor, ZAP 2.3 著者 Eigenbrot, C, Landgraf, K.E, Steffek, M. 登録日 2013-12-18 公開日 2014-06-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.04 Å) 主引用文献 An allosteric switch for pro-HGF/Met signaling using zymogen activator peptides. Nat.Chem.Biol., 10, 2014
8EBO	Homopurine parallel G-quadruplex from human chromosome 7 stabilized by K+ ions 分子名称: COBALT (III) ION, DNA (5'-D(*GP*AP*GP*GP*GP*AP*GP*GP*GP*AP*GP*GP*GP*AP*AP*AP*AP*GP*GP*GP*GP*A)-3'), N-METHYLMESOPORPHYRIN, ... 著者 Chen, E.V, Yatsunyk, L.A. 登録日 2022-08-31 公開日 2022-12-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Homopurine guanine-rich sequences in complex with N-methyl mesoporphyrin IX form parallel G-quadruplex dimers and display a unique symmetry tetrad. Bioorg.Med.Chem., 77, 2022
4OFD	Crystal Structure of mouse Neph1 D1-D2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Kin of IRRE-like protein 1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Ozkan, E, Garcia, K.C. 登録日 2014-01-14 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.94 Å) 主引用文献 Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis. Cell(Cambridge,Mass.), 156, 2014
4OUK	Crystal structure of a C6-C4 SN3 inhibited ESTERASE B from LACTOBACILLUS RHAMNOSIS 分子名称: (2R)-2,3-bis(hexyloxy)propyl hydrogen (S)-pentylphosphonate, Esterase B 著者 Colbert, D.A, Bennett, M.D, Lun, D.J, Holland, R, Delabre, M.-L, Loo, T.S, Anderson, B.F, Norris, G.E. 登録日 2014-02-17 公開日 2014-08-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of a C6-C4 SN3 inhibited ESTERASE B from LACTOBACILLUS RHAMNOSIS TO BE PUBLISHED
4U2R	Crystal structure of the GLUR2 ligand binding core (S1S2J, flip variant) in the apo state 分子名称: Glutamate receptor 2, SULFATE ION 著者 Duerr, K.L, Chen, L, Gouaux, E. 登録日 2014-07-17 公開日 2014-08-20 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.4114 Å) 主引用文献 Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States. Cell, 158, 2014
8DY7	Streptomyces venezuelae RNAP transcription open promoter complex with WhiA and WhiB transcription factors 分子名称: DNA (71-MER), DNA (78-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Lilic, M, Campbell, E.A. 登録日 2022-08-03 公開日 2023-03-01 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB. Proc.Natl.Acad.Sci.USA, 120, 2023
4OVQ	CRYSTAL STRUCTURE OF A TRAP PERIPLASMIC SOLUTE BINDING PROTEIN FROM ROSEOBACTER DENITRIFICANS, TARGET EFI-510230, WITH BOUND BETA-D-GLUCURONATE 分子名称: CHLORIDE ION, TRAP dicarboxylate ABC transporter, substrate-binding protein, ... 著者 Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) 登録日 2013-12-11 公開日 2014-01-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.501 Å) 主引用文献 Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry, 54, 2015
8EDH	Identification of a class of WNK isoform-specific inhibitors through high-throughput screening 分子名称: Serine/threonine-protein kinase WNK3, ethyl 1-(5,7-dimethoxy-4-methylquinolin-2-yl)piperidine-4-carboxylate 著者 Akella, R, Goldsmith, E.J. 登録日 2022-09-04 公開日 2023-03-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.111 Å) 主引用文献 Identification of a Class of WNK Isoform-Specific Inhibitors Through High-Throughput Screening. Drug Des Devel Ther, 17, 2023
8E2K	Cryo-EM structure of BIRC6/HtrA2-S306A 分子名称: Baculoviral IAP repeat-containing protein 6, Serine protease HTRA2, mitochondrial 著者 Hunkeler, M, Fischer, E.S. 登録日 2022-08-15 公開日 2023-02-15 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.21 Å) 主引用文献 Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases. Science, 379, 2023
4O7C	Crystal structure of the first bromodomain of human BRD4 in complex with SB-614067-R 分子名称: 1,2-ETHANEDIOL, 4-[(5Z)-5-(1-nitroso-2,3-dihydro-5H-inden-5-ylidene)-2-(piperidin-4-yl)-3,5-dihydro-4H-imidazol-4-ylidene]-1,4-dihydropyridine, Bromodomain-containing protein 4 著者 Ember, S.W, Zhu, J.-Y, Watts, C, Schonbrunn, E. 登録日 2013-12-24 公開日 2014-03-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Acetyl-lysine Binding Site of Bromodomain-Containing Protein 4 (BRD4) Interacts with Diverse Kinase Inhibitors. Acs Chem.Biol., 9, 2014
8DY9	Streptomyces venezuelae RNAP unconstrained open promoter complex with WhiA and WhiB transcription factors 分子名称: DNA (38-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lilic, M, Campbell, E.A. 登録日 2022-08-03 公開日 2023-03-01 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB. Proc.Natl.Acad.Sci.USA, 120, 2023
8ED0	Cryo-EM Structure of the P74-26 Tail Tube 分子名称: Tail Tube Protein gp93 著者 Agnello, E, Pajak, J, Liu, X, Kelch, B. 登録日 2022-09-02 公開日 2023-03-08 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.72 Å) 主引用文献 Conformational dynamics control assembly of an extremely long bacteriophage tail tube. J.Biol.Chem., 299, 2023
8EDX	Cryo-EM Structure of P74-26 tail-like tubes 分子名称: Tail Tube Protein gp93 著者 Agnello, E, Pajak, J, Liu, X, Kelch, B. 登録日 2022-09-06 公開日 2023-03-08 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.81 Å) 主引用文献 Conformational dynamics control assembly of an extremely long bacteriophage tail tube. J.Biol.Chem., 299, 2023
8E51	Crystal Structure of Iridescent Shark Catfish Cadherin-23 EC1-2 and Protocadherin-15 EC1-2 分子名称: CALCIUM ION, Cadherin-23, POTASSIUM ION, ... 著者 Scheib, E, Nisler, C.R, Sotomayor, M. 登録日 2022-08-19 公開日 2023-03-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.594 Å) 主引用文献 Interpreting the Evolutionary Echoes of a Protein Complex Essential for Inner-Ear Mechanosensation. Mol.Biol.Evol., 40, 2023
5K7S	MicroED structure of proteinase K at 1.6 A resolution 分子名称: CALCIUM ION, Proteinase K 著者 de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. 登録日 2016-05-26 公開日 2017-04-05 最終更新日 2018-08-22 実験手法 ELECTRON CRYSTALLOGRAPHY (1.6 Å) 主引用文献 Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
4O7H	Crystal structure of a glutathione S-transferase from Rhodospirillum rubrum F11, Target EFI-507460 分子名称: Glutathione S-transferase 著者 Kim, J, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Stead, M, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Attonito, J.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) 登録日 2013-12-24 公開日 2014-01-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of a glutathione S-transferase from Rhodospirillum rubrum F11, Target EFI-507460 TO BE PUBLISHED
3UO5	Aurora A in complex with YL1-038-31 分子名称: 4-{[4-(phenylamino)pyrimidin-2-yl]amino}benzoic acid, Serine/Threonine-Protein Kinase 6 著者 Martin, M.P, Zhu, J.-Y, Schonbrunn, E. 登録日 2011-11-16 公開日 2012-01-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7012 Å) 主引用文献 A Novel Mechanism by Which Small Molecule Inhibitors Induce the DFG Flip in Aurora A. Acs Chem.Biol., 7, 2012
4U01	HCV NS3/4A serine protease in complex with 6570 分子名称: (2S,3aS,10Z,11aS,12aR)-2-({8-fluoro-7-methoxy-2-[4-(propan-2-yl)-1,3-thiazol-2-yl]quinolin-4-yl}oxy)-5-methyl-N-[(1-methylcyclopropyl)sulfonyl]-4,14-dioxo-1,2,3,3a,4,5,6,7,8,9,11a,12,13,14-tetradecahydro-12aH-cyclopropa[m]pyrrolo[1,2-c][1,3,6]triazacyclotetradecine-12a-carboxamide, CHLORIDE ION, NS4A protein, ... 著者 Parsy, C.C, Alexandre, F.-R, Brandt, G, Caillet, C, Chaves, D, Derock, M, Gloux, D, Griffon, Y, Lallos, L.B, Leroy, F, Liuzzi, M, Loi, A.-G, Mayes, B, Moulat, L, Moussa, A, Chiara, M, Roques, V, Rosinovsky, E, Seifer, M, Stewart, A, Wang, J, Standring, D, Surleraux, D. 登録日 2014-07-11 公開日 2015-07-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Discovery and structural diversity of the hepatitis C virus NS3/4A serine protease inhibitor series leading to clinical candidate IDX320. Bioorg.Med.Chem.Lett., 25, 2015
4U0O	Crystal structure of Thermosynechococcus elongatus Lipoyl Synthase 2 complexed with MTA and DTT 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 5'-DEOXY-5'-METHYLTHIOADENOSINE, IRON/SULFUR CLUSTER, ... 著者 Harmer, J.E, Hiscox, M.J, Dinis, P.C, Sandy, J, Roach, P.L. 登録日 2014-07-13 公開日 2014-08-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structures of lipoyl synthase reveal a compact active site for controlling sequential sulfur insertion reactions. Biochem.J., 464, 2014
8E5F	Cryo-EM of P. calidifontis cytochrome filament 分子名称: HEME C, c-type cytochrome 著者 Wang, F, Cvirkaite-Krupovic, V, Krupovic, M, Egelman, E.H. 登録日 2022-08-22 公開日 2023-05-10 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Extracellular cytochrome nanowires appear to be ubiquitous in prokaryotes. Cell, 186, 2023
5L85	Solution structure of the complex between human ZNHIT3 and NUFIP1 proteins 分子名称: Nuclear fragile X mental retardation-interacting protein 1, Zinc finger HIT domain-containing protein 3 著者 Quinternet, M, Chagot, M.-E, Manival, X. 登録日 2016-06-07 公開日 2016-08-31 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Structural Features of the Box C/D snoRNP Pre-assembly Process Are Conserved through Species. Structure, 24, 2016
4P0L	Crystal Structure of Double Loop-Swapped Interleukin-36Ra With Additional Point Mutations 分子名称: Interleukin-36 receptor antagonist/Interleukin-36 gamma chimera protein 著者 Guenther, S, Sundberg, E.J. 登録日 2014-02-21 公開日 2014-06-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor. J Immunol., 193, 2014
8EC3	The crystal structure of the complement inhibitory domain of Borrelia hermsii FbpC. 分子名称: Fibronectin-binding protein, MAGNESIUM ION 著者 Booth, C.E, Garcia, B.L. 登録日 2022-09-01 公開日 2023-06-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Conformational dynamics of complement protease C1r inhibitor proteins from Lyme disease- and relapsing fever-causing spirochetes. J.Biol.Chem., 299, 2023
8DST	Cryo-EM of NBD-ffsy filaments (class 2) 分子名称: NBD-ffsy peptide 著者 Wang, F, Guo, J, Xu, B, Egelman, E.H. 登録日 2022-07-22 公開日 2023-05-31 最終更新日 2023-09-27 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cell spheroid creation by transcytotic intercellular gelation. Nat Nanotechnol, 18, 2023
8E5G	Cryo-EM of A. veneficus cytochrome filament 分子名称: HEME C, c-type cytochrome 著者 Wang, F, Baquero, D.P, Krupovic, M, Egelman, E.H. 登録日 2022-08-22 公開日 2023-05-10 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Extracellular cytochrome nanowires appear to be ubiquitous in prokaryotes. Cell, 186, 2023

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