PDB: 160289 件ウェブページステータス検索Chemie searchBIRD

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2N4S	NMR structure of Fbp28 WW domain L453E mutant 分子名称: Transcription elongation regulator 1 著者 Medina, J, Macias, M, Martin-Malpartida, P, Scheraga, H.A. 登録日 2015-07-01 公開日 2015-10-21 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Preventing fibril formation of a protein by selective mutation. Proc.Natl.Acad.Sci.USA, 112, 2015
2N4W	NMR structure of Fbp28 WW domain T456Y mutant 分子名称: Transcription elongation regulator 1 著者 Medina, J, Macias, M, Martin-Malpartida, P, Scheraga, H.A. 登録日 2015-07-01 公開日 2015-10-21 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Preventing fibril formation of a protein by selective mutation. Proc.Natl.Acad.Sci.USA, 112, 2015
6LBW	Crystal structure of Ag-mediated base pairs in uncanonical DNA duplex 分子名称: DNA (5'-D(*CP*GP*(CBR)P*GP*AP*(LCC)P*TP*CP*GP*CP*G)-3'), SILVER ION 著者 Aoyama, H, Obika, S, Nakagawa, O. 登録日 2019-11-15 公開日 2020-11-18 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.501 Å) 主引用文献 Crystallographic Structure of Novel Types of Ag I -Mediated Base Pairs in Non-canonical DNA Duplex Containing 2'-O,4'-C-Methylene Bridged Nucleic Acids. Chemistry, 27, 2021
2N4T	NMR structure of Fbp28 WW domain L453W mutant 分子名称: Transcription elongation regulator 1 著者 Medina, J, Macias, M, Martin-Malpartida, P, Scheraga, H.A. 登録日 2015-07-01 公開日 2015-10-21 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Preventing fibril formation of a protein by selective mutation. Proc.Natl.Acad.Sci.USA, 112, 2015
4NO5	Crystal structure of non-phosphorylated form of AMPD2 phosphopeptide bound to HLA-A2 分子名称: 1,2-ETHANEDIOL, AMP deaminase 2, Beta-2-microglobulin, ... 著者 Mohammed, F, Stones, D.H, Willcox, B.E. 登録日 2013-11-19 公開日 2014-12-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.101 Å) 主引用文献 The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status. Oncotarget, 8, 2017
6V90	Crystal structure of the p300 acetyltransferase domain with AcCoA competitive inhibitor 12 分子名称: (2R)-2-{[2-(4-cyanophenyl)ethyl]amino}-N-[5-(1-methyl-1H-pyrazol-4-yl)pyridin-2-yl]-2-phenylacetamide, CHLORIDE ION, Histone acetyltransferase p300, ... 著者 Gardberg, A.S. 登録日 2019-12-12 公開日 2020-04-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Early Drug-Discovery Efforts towards the Identification of EP300/CBP Histone Acetyltransferase (HAT) Inhibitors. Chemmedchem, 15, 2020
5N6F	Crystal structure of TGT in complex with guanine fragment 分子名称: DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, GUANINE, ... 著者 Hassaan, E, Heine, A, Klebe, G. 登録日 2017-02-15 公開日 2018-03-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.11909521 Å) 主引用文献 Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening Strategies. Chemmedchem, 15, 2020
6V8N	Crystal structure of the p300 acetyltransferase domain with AcCoA competitive inhibitor 17 分子名称: (2R)-2-{[(2S)-2-(4-cyanophenyl)propyl]amino}-N-[5-(1-methyl-1H-pyrazol-4-yl)pyridin-2-yl]-2-phenylacetamide, CHLORIDE ION, Histone acetyltransferase p300, ... 著者 Gardberg, A.S, Wilson, J.E. 登録日 2019-12-11 公開日 2020-04-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Early Drug-Discovery Efforts towards the Identification of EP300/CBP Histone Acetyltransferase (HAT) Inhibitors. Chemmedchem, 15, 2020
6V8B	Crystal structure of the p300 acetyltransferase domain with AcCoA competitive inhibitor 1 分子名称: 4-(2-{[(1R)-2-(1H-indol-3-yl)-2-oxo-1-phenylethyl]amino}ethyl)benzene-1-sulfonamide, CHLORIDE ION, Histone acetyltransferase p300, ... 著者 Gardberg, A.S. 登録日 2019-12-10 公開日 2020-04-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.13 Å) 主引用文献 Early Drug-Discovery Efforts towards the Identification of EP300/CBP Histone Acetyltransferase (HAT) Inhibitors. Chemmedchem, 15, 2020
7EQV	Crystal structure of JMJD2A complexed with 3,4-dihydroxybenzoic acid 分子名称: 3,4-DIHYDROXYBENZOIC ACID, CHLORIDE ION, Lysine-specific demethylase 4A, ... 著者 Fang, W.-K, Yang, S.-M, Wang, W.-C. 登録日 2021-05-04 公開日 2022-05-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Natural product myricetin is a pan-KDM4 inhibitor which with poly lactic-co-glycolic acid formulation effectively targets castration-resistant prostate cancer. J.Biomed.Sci., 29, 2022
8SWL	Substrate free structure of cytochrome P450 CYP105Q4 from mycobacterium marinum 分子名称: Cytochrome P450 105Q4 Cyp105Q4, PROTOPORPHYRIN IX CONTAINING FE, TRIETHYLENE GLYCOL 著者 Mohamed, H.A, Bruning, J.B, Bell, S.G. 登録日 2023-05-19 公開日 2024-03-27 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (3.06 Å) 主引用文献 Structural determination and characterisation of the CYP105Q4 cytochrome P450 enzyme from Mycobacterium marinum. Arch.Biochem.Biophys., 754, 2024
4E7R	Thrombin in complex with 3-amidinophenylalanine inhibitor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[(2S)-3-[4-(2-aminoethyl)piperidin-1-yl]-2-{[(2',4'-dichlorobiphenyl-3-yl)sulfonyl]amino}-3-oxopropyl]benzenecarboximidamide, GLYCEROL, ... 著者 Ruehmann, E, Heine, A, Klebe, G. 登録日 2012-03-19 公開日 2012-06-20 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 New 3-amidinophenylalanine-derived inhibitors of matriptase MEDCHEMCOMM, 3, 2012
8FDG	Cryo-EM structure of coagulation factor V short 分子名称: Coagulation factor V 著者 Mohammed, B.M, Pelc, L.A, Rau, M.J, Di Cera, E. 登録日 2022-12-03 公開日 2023-03-15 最終更新日 2023-07-12 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structure of coagulation factor V short. Blood, 141, 2023
7JQ3	Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI6 分子名称: 3C-like proteinase, N-[(benzyloxy)carbonyl]-O-tert-butyl-L-threonyl-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide 著者 Yang, K, Liu, W. 登録日 2020-08-10 公開日 2020-12-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*. Chemmedchem, 16, 2021
7JQ0	Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI3 分子名称: 3C-like proteinase, N-[(benzyloxy)carbonyl]-L-valyl-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide 著者 Yang, K, Liu, W. 登録日 2020-08-10 公開日 2020-12-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*. Chemmedchem, 16, 2021
7JQ2	Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI5 分子名称: 3C-like proteinase, N-[(benzyloxy)carbonyl]-L-valyl-3-cyclohexyl-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-alaninamide 著者 Yang, K, Liu, W. 登録日 2020-08-10 公開日 2020-12-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*. Chemmedchem, 16, 2021
7JPY	Crystal structure of the SARS-CoV-2 main protease in its apo-form 分子名称: 3C-like proteinase 著者 Yang, K, Liu, W. 登録日 2020-08-10 公開日 2020-12-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*. Chemmedchem, 16, 2021
7JQ4	Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI7 分子名称: 3C-like proteinase, N-[(benzyloxy)carbonyl]-O-tert-butyl-L-threonyl-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide 著者 Yang, K, Liu, W. 登録日 2020-08-10 公開日 2020-12-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*. Chemmedchem, 16, 2021
3UN0	Crystal Structure of MDC1 FHA Domain 分子名称: Mediator of DNA damage checkpoint protein 1, SULFATE ION 著者 Clapperton, J.A, Lloyd, J, Haire, L.F, Li, J, Smerdon, S.J. 登録日 2011-11-15 公開日 2011-12-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator. Nucleic Acids Res., 40, 2012
7JQ1	Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI4 分子名称: 3C-like proteinase, N-[(benzyloxy)carbonyl]-L-valyl-N-{(2S)-1-hydroxy-3-[(3R)-2-oxo-3,4-dihydro-2H-pyrrol-3-yl]propan-2-yl}-L-phenylalaninamide 著者 Yang, K, Liu, W. 登録日 2020-08-10 公開日 2020-12-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*. Chemmedchem, 16, 2021
7JPZ	Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI1 分子名称: (phenylmethyl) N-[(2S)-1-oxidanylidene-1-[[(2S)-1-oxidanyl-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-3-phenyl-propan-2-yl]carbamate, 3C-like proteinase 著者 Yang, K, Liu, W. 登録日 2020-08-10 公開日 2020-12-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*. Chemmedchem, 16, 2021
7JQ5	Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI8 分子名称: 3C-like proteinase, N-[(BENZYLOXY)CARBONYL]-O-(TERT-BUTYL)-L-THREONYL-3-CYCLOHEXYL-N-[(1S)-2-HYDROXY-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}ETHYL]-L-ALANINAMIDE 著者 Yang, K, Liu, W. 登録日 2020-08-10 公開日 2020-12-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*. Chemmedchem, 16, 2021
1YQS	Inhibition of the R61 DD-Peptidase by N-benzoyl-beta-sultam 分子名称: 2-(BENZOYLAMINO)ETHANESULFONIC ACID, D-alanyl-D-alanine carboxypeptidase, GLYCEROL 著者 Ahmed, N, Cordaro, M, Laws, A.P, Delmarcelle, M, Silvaggi, N.R, Kelly, J.A, Page, M.I. 登録日 2005-02-02 公開日 2005-06-28 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Inactivation of Bacterial dd-Peptidase by beta-Sultams. Biochemistry, 44, 2005
4U5N	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-L-lysyl-N-[(1R,2S,3R)-1-{[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]amino}-1,3-dihydroxybutan-2-yl]glycinamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-25 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U5S	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N-[(2S)-2-[(N~2~-acetyl-D-lysyl)amino]-3-(pyridin-3-ylmethoxy)propyl]-L-allothreonyl-D-phenylalaninamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-25 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015

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