5N6F

Crystal structure of TGT in complex with guanine fragment

Summary for 5N6F

Entry DOI	10.2210/pdb5n6f/pdb
Descriptor	Queuine tRNA-ribosyltransferase, ZINC ION, DIMETHYL SULFOXIDE, ... (7 entities in total)
Functional Keywords	tgt, trna, guanine exchange enzyme, transglycosylase, transferase
Biological source	Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
Total number of polymer chains	1
Total formula weight	42314.44
Authors	Hassaan, E.,Heine, A.,Klebe, G. (deposition date: 2017-02-15, release date: 2018-03-07, Last modification date: 2024-01-17)
Primary citation	Hassaan, E.,Eriksson, P.O.,Geschwindner, S.,Heine, A.,Klebe, G. Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening Strategies. Chemmedchem, 15:324-337, 2020 Cited by PubMed: 31808981 DOI: 10.1002/cmdc.201900604 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.11909520042 Å)

Structure validation