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7QRE
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BU of 7qre by Molmil
Structure of the hetero-tetramer complex between precursor membrane protein fragment (pr) and envelope protein (E) from tick-borne encephalitis virus
分子名称: ACETATE ION, Envelope protein E, Genome polyprotein, ...
著者Vaney, M.C, Dellarole, M, Rey, F.A.
登録日2022-01-11
公開日2022-05-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Evolution and activation mechanism of the flavivirus class II membrane-fusion machinery.
Nat Commun, 13, 2022
7QEZ
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BU of 7qez by Molmil
Crystal structure of the SARS-CoV-2 RBD in complex with the ultrapotent antibody CV2.1169 and CR3022
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CR3022 heavy chain, CR3022 light chain, ...
著者Fernandez, I, Rey, F.A.
登録日2021-12-03
公開日2022-05-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.
J.Exp.Med., 219, 2022
7QRF
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BU of 7qrf by Molmil
Structure of the dimeric complex between precursor membrane ectodomain (prM) and envelope protein ectodomain (E) from tick-borne encephalitis virus
分子名称: 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Envelope protein E, ...
著者Vaney, M.C, Rouvinski, A, Rey, F.A.
登録日2022-01-11
公開日2022-05-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Evolution and activation mechanism of the flavivirus class II membrane-fusion machinery.
Nat Commun, 13, 2022
1C7Z
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BU of 1c7z by Molmil
REGULATORY COMPLEX OF FRUCTOSE-2,6-BISPHOSPHATASE
分子名称: FRUCTOSE-2,6-BISPHOSPHATASE, GLYCERALDEHYDE-3-PHOSPHATE, PHOSPHATE ION
著者Lee, Y.H, Olson, T.W, McClard, R.W, Witte, J.F, McFarlan, S.C, Banaszak, L.J, Levitt, D.G, Lange, A.J.
登録日2000-04-03
公開日2003-06-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Reaction Mechanism of Fructose-2,6-bisphosphatase Suggested by the Crystal Structures of a pseudo-Michaelis complex and Metabolite Complexes
To be Published
6ETY
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BU of 6ety by Molmil
X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a inhibitor JHU3371
分子名称: (2~{S})-2-[[(2~{R})-4-methyl-1-oxidanyl-1-oxidanylidene-pentan-2-yl]carbamoyloxy]pentanedioic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Barinka, C, Novakova, Z, Motlova, L.
登録日2017-10-27
公開日2018-11-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structural and computational basis for potent inhibition of glutamate carboxypeptidase II by carbamate-based inhibitors.
Bioorg.Med.Chem., 27, 2019
6FE5
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BU of 6fe5 by Molmil
X-ray structure of human glutamate carboxypeptidase II (GCPII) - the E424M inactive mutant, in complex with a inhibitor JHU 2249
分子名称: (2~{S})-2-[[(2~{S})-4-methyl-1-oxidanyl-1-oxidanylidene-pentan-2-yl]carbamoylamino]pentanedioic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Barinka, C, Novakova, Z, Motlova, L.
登録日2017-12-29
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Structural and computational basis for potent inhibition of glutamate carboxypeptidase II by carbamate-based inhibitors.
Bioorg.Med.Chem., 27, 2019
6FF3
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BU of 6ff3 by Molmil
Crystal structure of Drosophila neural ectodermal development factor Imp-L1 with Human IGF-I
分子名称: Insulin-like growth factor I, Neural/ectodermal development factor IMP-L2
著者Brzozowski, A.M, Kulahin, N, Kristensen, O, Schluckebier, G, Meyts, P.D, Viola, C.M.
登録日2018-01-03
公開日2018-09-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones.
Nat Commun, 9, 2018
1C81
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BU of 1c81 by Molmil
MICHAELIS COMPLEX OF FRUCTOSE-2,6-BISPHOSPHATASE
分子名称: 2,5-anhydro-1-deoxy-1-phosphono-6-O-phosphono-D-glucitol, FRUCTOSE-2,6-BISPHOSPHATASE
著者Lee, Y.H, Olson, T.W, McClard, R.W, Witte, J.F, McFarlan, S.C, Banaszak, L.J, Levitt, D.G, Lange, A.J.
登録日2000-04-03
公開日2003-06-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Reaction Mechanism of Fructose-2,6-bisphosphatase Suggested by the Crystal Structures of a pseudo-Michaelis complex and Metabolite Complexes
To be Published
6F5L
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BU of 6f5l by Molmil
X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a inhibitor JHU2379
分子名称: (2~{S})-2-[[(2~{S})-4-methyl-1-oxidanyl-1-oxidanylidene-pentan-2-yl]carbamoyloxy]pentanedioic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Barinka, C, Novakova, Z, Motlova, L.
登録日2017-12-01
公開日2018-12-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structural and computational basis for potent inhibition of glutamate carboxypeptidase II by carbamate-based inhibitors.
Bioorg.Med.Chem., 27, 2019
6FEY
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BU of 6fey by Molmil
Crystal structure of Drosophila neural ectodermal development factor Imp-L2 with Drosophila DILP5 insulin
分子名称: Neural/ectodermal development factor IMP-L2, Probable insulin-like peptide 5
著者Brzozowski, A.M, Kulahin, N, Kristensen, O, Schluckebier, G, Meyts, P.D.
登録日2018-01-03
公開日2018-09-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.48 Å)
主引用文献Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones.
Nat Commun, 9, 2018
1C43
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BU of 1c43 by Molmil
MUTANT HUMAN LYSOZYME WITH FOREIGN N-TERMINAL RESIDUES
分子名称: PROTEIN (HUMAN LYSOZYME), SODIUM ION
著者Takano, K, Tsuchimori, K, Yamagata, Y, Yutani, K.
登録日1999-08-03
公開日1999-08-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Effect of foreign N-terminal residues on the conformational stability of human lysozyme.
Eur.J.Biochem., 266, 1999
1C45
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BU of 1c45 by Molmil
MUTANT HUMAN LYSOZYME WITH FOREIGN N-TERMINAL RESIDUES
分子名称: PROTEIN (LYSOZYME), SODIUM ION
著者Takano, K, Tsuchimori, K, Yamagata, Y, Yutani, K.
登録日1999-08-03
公開日1999-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Effect of foreign N-terminal residues on the conformational stability of human lysozyme.
Eur.J.Biochem., 266, 1999
1C49
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BU of 1c49 by Molmil
STRUCTURAL AND FUNCTIONAL DIFFERENCES OF TWO TOXINS FROM THE SCORPION PANDINUS IMPERATOR
分子名称: TOXIN K-BETA
著者Klenk, K.C, Tenenholz, T.C, Matteson, D.R, Rogowski, R.S, Blaustein, M.P, Weber, D.J.
登録日1999-08-17
公開日2000-03-22
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structural and functional differences of two toxins from the scorpion Pandinus imperator.
Proteins, 38, 2000
6G01
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BU of 6g01 by Molmil
Complex of neuraminidase from H1N1 influenza virus with tamiphosphor monomethyl ester
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Pachl, P, Pokorna, J.
登録日2018-03-15
公開日2019-01-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献DNA-linked inhibitor antibody assay (DIANA) as a new method for screening influenza neuraminidase inhibitors.
Biochem. J., 475, 2018
1C80
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BU of 1c80 by Molmil
REGULATORY COMPLEX OF FRUCTOSE-2,6-BISPHOSPHATASE
分子名称: FRUCTOSE-2,6-BISPHOSPHATASE, GUANOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION
著者Lee, Y.H, Olson, T.W, McClard, R.W, Witte, J.F, McFarlan, S.C, Banaszak, L.J, Levitt, D.G, Lange, A.J.
登録日2000-04-03
公開日2003-06-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Reaction Mechanism of Fructose-2,6-bisphosphatase Suggested by the Crystal Structures of a pseudo-Michaelis complex and Metabolite Complexes
To be Published
7QOX
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BU of 7qox by Molmil
Factor XI and Plasma Kallikrein apple domain structures reveals different kininogen bound complexes
分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ...
著者Li, C, Awital, B, Wong, S, Dreveny, I, Meijers, J, Emsley, J.
登録日2021-12-29
公開日2023-01-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI.
J Thromb Haemost, 17, 2019
7QOT
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BU of 7qot by Molmil
Factor XI and Plasma Kallikrein apple domain structures reveals different kininogen bound complexes
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor XIa heavy chain, Kininogen-1 light chain, ...
著者Li, C, Awital, B, Wong, S, Dreveny, I, Meijers, J, Emsley, J.
登録日2021-12-28
公開日2023-01-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI.
J Thromb Haemost, 17, 2019
1AZE
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BU of 1aze by Molmil
NMR STRUCTURE OF THE COMPLEX BETWEEN THE C32S-Y7V MUTANT OF THE NSH3 DOMAIN OF GRB2 WITH A PEPTIDE FROM SOS, 10 STRUCTURES
分子名称: GRB2, SOS
著者Vidal, M, Gincel, E, Goudreau, N, Cornille, F, Parker, F, Duchesne, M, Tocque, B, Garbay, C, Roques, B.P.
登録日1997-11-17
公開日1999-05-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Molecular and cellular analysis of Grb2 SH3 domain mutants: interaction with Sos and dynamin.
J.Mol.Biol., 290, 1999
8DMH
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BU of 8dmh by Molmil
Lymphocytic choriomeningitis virus glycoprotein in complex with neutralizing antibody M28
分子名称: 18.5C-M28 Fab Heavy Chain, 18.5C-M28 Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Moon-Walker, A, Hastie, K.M, Zyla, D.S, Saphire, E.O.
登録日2022-07-08
公開日2023-04-12
最終更新日2023-05-03
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献Structural basis for antibody-mediated neutralization of lymphocytic choriomeningitis virus.
Cell Chem Biol, 30, 2023
8DMI
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BU of 8dmi by Molmil
Lymphocytic choriomeningitis virus glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein G1, ...
著者Moon-Walker, A, Hastie, K.M, Zyla, D.S, Saphire, E.O.
登録日2022-07-08
公開日2023-04-12
最終更新日2023-05-03
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Structural basis for antibody-mediated neutralization of lymphocytic choriomeningitis virus.
Cell Chem Biol, 30, 2023
7QQB
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BU of 7qqb by Molmil
Crystal structure of the envelope glycoprotein complex of Puumala virus in complex with the scFv fragment of the broadly neutralizing human antibody ADI-42898
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, GLYCEROL, ...
著者Serris, A, Rey, F.A, Guardado-Calvo, P.
登録日2022-01-07
公開日2023-06-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody.
Sci Transl Med, 15, 2023
7RTC
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BU of 7rtc by Molmil
Crystal structure of the ARM domain from Drosophila SARM1 in complex with NaMN
分子名称: NAD(+) hydrolase sarm1, NICOTINATE MONONUCLEOTIDE
著者Gu, W, Ve, T, Kobe, B.
登録日2021-08-13
公開日2021-09-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.31 Å)
主引用文献Nicotinic acid mononucleotide is an allosteric SARM1 inhibitor promoting axonal protection.
Exp Neurol, 345, 2021
6FN6
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BU of 6fn6 by Molmil
Modifying region (DH-ER-KR) of an insect fatty acid synthase (FAS)
分子名称: 1,2-ETHANEDIOL, BROMIDE ION, Fatty acid synthase 1, ...
著者Benning, F.M.C, Bukhari, H.S.T, Jakob, R.P, Maier, T.
登録日2018-02-02
公開日2019-03-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Modifying region (DH-ER-KR) of an insect fatty acid synthase (FAS)
To Be Published
8DPM
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BU of 8dpm by Molmil
Structure of EBOV GP lacking the mucin-like domain with 9.20.1A2 Fab and 6D6 scFv bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 6D6 scFv, Antibody 9.20.1A2 Fab heavy chain, ...
著者Yu, X, Saphire, E.O.
登録日2022-07-15
公開日2023-07-19
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The evolution and determinants of neutralization of potent head-binding antibodies against Ebola virus.
Cell Rep, 42, 2023
8DPL
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BU of 8dpl by Molmil
Structure of EBOV GP lacking the mucin-like domain with 2.1.1D5 scFv and 6D6 scFv bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2.1.1D5 heavy chain variable domain, 2.1.1D5 light chain variable domain, ...
著者Yu, X, Saphire, E.O.
登録日2022-07-15
公開日2023-07-19
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (2.53 Å)
主引用文献The evolution and determinants of neutralization of potent head-binding antibodies against Ebola virus.
Cell Rep, 42, 2023

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