PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

---

7LID	The structure of the insect olfactory receptor OR5 from Machilis hrabei in complex with eugenol 分子名称: 2-methoxy-4-(prop-2-en-1-yl)phenol, MhOR5 著者 del Marmol, J, Ruta, V. 登録日 2021-01-27 公開日 2021-08-11 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 The structural basis of odorant recognition in insect olfactory receptors. Nature, 597, 2021
7QZ9	Transcriptional regulator LmrR with Trp-67 and Trp-96 replaced by the unnatural amino acid 5,6-difluoroTrp 分子名称: Transcriptional regulator, PadR-like family 著者 Thunnissen, A.M.W.H. 登録日 2022-01-30 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
4WD9	Crystal structure of tRNA-dependent lantibiotic dehydratase NisB in complex with NisA leader peptide 分子名称: Nisin biosynthesis protein NisB 著者 Hao, Y, Nair, S.K. 登録日 2014-09-08 公開日 2014-10-29 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB. Nature, 517, 2015
7LGQ	Cyanophycin synthetase 1 from Synechocystis sp. UTEX2470 with ATP and 8x(Asp-Arg)-Asn 分子名称: 8x(Asp-Arg)-Asn, ADENOSINE-5'-TRIPHOSPHATE, Cyanophycin synthase, ... 著者 Sharon, I, Grogg, M, Hilvert, D, Schmeing, T.M. 登録日 2021-01-20 公開日 2021-08-18 最終更新日 2021-10-06 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structures and function of the amino acid polymerase cyanophycin synthetase. Nat.Chem.Biol., 17, 2021
1MN1	MANGANESE PEROXIDASE SUBSTRATE BINDING SITE MUTANT D179N 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, MANGANESE PEROXIDASE, ... 著者 Sundaramoorthy, M, Poulos, T.L. 登録日 1997-04-26 公開日 1997-09-04 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structures of substrate binding site mutants of manganese peroxidase. J.Biol.Chem., 272, 1997
4URP	The Crystal structure of Nitroreductase from Saccharomyces cerevisiae 分子名称: FATTY ACID REPRESSION MUTANT PROTEIN 2 著者 Song, H.-N, Woo, E.-J, Bang, S.-Y, Jung, D.-G, Park, S.-G. 登録日 2014-07-01 公開日 2015-04-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.991 Å) 主引用文献 Crystal Structure of the Fungal Nitroreductase Frm2 from Saccharomyces Cerevisiae. Protein Sci., 24, 2015
7LHI	Cryo-EM structure of E. coli P pilus tip assembly intermediate PapC-PapD-PapK-PapF-PapG 分子名称: Chaperone protein PapD, Fimbrial adapter PapK, Fimbrial protein, ... 著者 Du, M, Yuan, Z, Werneburg, G, Henderson, N, Chauhan, H, Kovach, A, Zhao, G, Johl, J, Li, H, Thanassi, D. 登録日 2021-01-23 公開日 2021-08-11 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (7.6 Å) 主引用文献 Processive dynamics of the usher assembly platform during uropathogenic Escherichia coli P pilus biogenesis. Nat Commun, 12, 2021
4V05	FGFR1 in complex with AZD4547. 分子名称: 1,2-ETHANEDIOL, FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ... 著者 Tucker, J, Klein, T, Breed, J, Breeze, A, Overman, R, Phillips, C, Norman, R.A. 登録日 2014-09-10 公開日 2014-12-10 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Structural Insights Into Fgfr Kinase Isoform Selectivity: Diverse Binding Modes of Azd4547 and Ponatinib in Complex with Fgfr1 and Fgfr4 Structure, 22, 2014
7LGJ	Cyanophycin synthetase 1 from Synechocystis sp. UTEX2470 with ADPCP and 8x(Asp-Arg)-NH2 分子名称: 8x(Asp-Arg)-NH2, Cyanophycin synthase, MAGNESIUM ION, ... 著者 Sharon, I, Grogg, M, Hilvert, D, Schmeing, T.M. 登録日 2021-01-20 公開日 2021-08-18 最終更新日 2021-10-06 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structures and function of the amino acid polymerase cyanophycin synthetase. Nat.Chem.Biol., 17, 2021
7QHZ	Crystal structure of KLK6 in complex with compound DKFZ917 分子名称: (5~{R})-3-(4-carbamimidoylphenyl)-~{N}-[(1~{S})-1-naphthalen-1-ylpropyl]-2-oxidanylidene-1,3-oxazolidine-5-carboxamide, GLYCEROL, Kallikrein-6 著者 Jagtap, P.K.A, Baumann, A, Lohbeck, J, Isak, D, Miller, A, Hennig, J. 登録日 2021-12-14 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Scalable synthesis and structural characterization of reversible KLK6 inhibitors. Rsc Adv, 12, 2022
7LCC	Helitron transposase bound to LTS 分子名称: Helraiser K1068Q, LTS, ZINC ION 著者 Kosek, D, Dyda, F. 登録日 2021-01-10 公開日 2021-08-25 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.66 Å) 主引用文献 The large bat Helitron DNA transposase forms a compact monomeric assembly that buries and protects its covalently bound 5'-transposon end. Mol.Cell, 81, 2021
2FW3	Crystal structure of rat carnitine palmitoyltransferase 2 in complex with antidiabetic drug ST1326 分子名称: (3R)-3-{[(TETRADECYLAMINO)CARBONYL]AMINO}-4-(TRIMETHYLAMMONIO)BUTANOATE, Carnitine O-palmitoyltransferase II, mitochondrial 著者 Rufer, A.C, Thoma, R, Benz, J, Stihle, M, Gsell, B, De Roo, E, Banner, D.W, Mueller, F, Chomienne, O, Hennig, M. 登録日 2006-02-01 公開日 2007-02-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The crystal structure of carnitine palmitoyltransferase 2 and implications for diabetes treatment Structure, 14, 2006
4O4P	Structure of P450 BM3 A82F F87V in complex with S-omeprazol 分子名称: 6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole, Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE 著者 Leys, D. 登録日 2013-12-19 公開日 2014-01-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Human P450-like oxidation of diverse proton pump inhibitor drugs by 'gatekeeper' mutants of flavocytochrome P450 BM3. Biochem.J., 460, 2014
7QZ5	Transcriptional regulator LmrR with Trp-67 and Trp-96 replaced by the unnatural amino acid 5-fluoroTrp 分子名称: Transcriptional regulator, PadR-like family 著者 Thunnissen, A.M.W.H. 登録日 2022-01-30 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
7QBW	Human Cyclophilin A double mutant C52AK125C 分子名称: GLYCEROL, Peptidyl-prolyl cis-trans isomerase A 著者 Fischer, L, Buratto, J, Langlois d'Estaintot, B. 登録日 2021-11-19 公開日 2022-11-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Human Cyclophilin A double mutant C52AK125C To Be Published
7LIB	X-ray crystal structure of a cyclic peptide containing beta-2-microglobulin (63-69) and a gamma-methylornithine turn unit 分子名称: Cyclic peptide ORD-TYR-LEU-LEU-PHI-TYR-THR-GLU-GMO-LYS-VAL-THR-MVA-THR-VAL-LYS 著者 Wierzbicki, M, Nowick, J.S, Li, X. 登録日 2021-01-26 公開日 2021-08-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 An Improved Turn Structure for Inducing beta-Hairpin Formation in Peptides. Angew.Chem.Int.Ed.Engl., 60, 2021
7Q9W	Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with 4-(aminomethyl)pyridin-2-amine 分子名称: 4-(aminomethyl)pyridin-2-amine, Cholinephosphate cytidylyltransferase, Guanidinium 著者 Duclovel, C, Gelin, M, Krimm, I, Cerdan, R, Guichou, J.-F. 登録日 2021-11-15 公開日 2022-11-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors. To Be Published
7QA7	Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with Cyclopropanemethylamine 分子名称: Cholinephosphate cytidylyltransferase, cyclopropylmethanamine 著者 Duclovel, C, Gelin, M, Krimm, I, Cerdan, R, Guichou, J.-F. 登録日 2021-11-16 公開日 2022-11-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors To Be Published
7Q9V	Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with 1-(1,3-oxazol-4-yl)methanamine 分子名称: 1,3-oxazol-4-ylmethanamine, Cholinephosphate cytidylyltransferase, Guanidinium 著者 Duclovel, C, Gelin, M, Krimm, I, Cerdan, R, Guichou, J.-F. 登録日 2021-11-15 公開日 2022-11-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors To Be Published
7LAS	Cryo-EM structure of PCV2 Replicase bound to ssDNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent helicase Rep, DNA (5'-D(P*GP*AP*TP*CP*GP*AP*TP*CP*GP*A)-3'), ... 著者 Khayat, R. 登録日 2021-01-06 公開日 2021-08-25 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Mechanism of DNA Interaction and Translocation by the Replicase of a Circular Rep-Encoding Single-Stranded DNA Virus. Mbio, 12, 2021
7Q72	Structure of Pla1 in complex with Red1 分子名称: NURS complex subunit red1, Poly(A) polymerase pla1 著者 Soni, K, Wild, K, Sinning, I. 登録日 2021-11-09 公開日 2022-12-07 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex. Nat Commun, 14, 2023
3GN0	Crystal structure of human arginase I in complex with difluoromethylornithine (DFMO) 分子名称: ALPHA-DIFLUOROMETHYLORNITHINE, Arginase-1, MANGANESE (II) ION 著者 Di Costanzo, L, Christianson, D.W. 登録日 2009-03-15 公開日 2010-02-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Binding of alpha,alpha-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor Design J.Med.Chem., 54, 2011
7QAD	Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with 1,4-Oxazepane hydrochloride 分子名称: 1,4-oxazepane, Cholinephosphate cytidylyltransferase, Guanidinium 著者 Duclovel, C, Gelin, M, Krimm, I, Cerdan, R, Guichou, J.-F. 登録日 2021-11-16 公開日 2022-11-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors. To Be Published
4NZN	Crystal structure of the catalytic domain of PPIP5K2 in complex with AMPPNP and 2-O-BN-5-PA-INSP4 分子名称: (2-{[(1s,2R,3R,4r,5S,6S)-4-(benzyloxy)-2,3,5,6-tetrakis(phosphonooxy)cyclohexyl]oxy}-2-oxoethyl)phosphonic acid, Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2, MAGNESIUM ION, ... 著者 Wang, H, Shears, S.B. 登録日 2013-12-12 公開日 2014-04-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Synthetic Inositol Phosphate Analogs Reveal that PPIP5K2 Has a Surface-Mounted Substrate Capture Site that Is a Target for Drug Discovery. Chem.Biol., 21, 2014
7QD3	Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with morpholine 分子名称: Cholinephosphate cytidylyltransferase, morpholine 著者 Duclovel, C, Gelin, M, Krimm, I, Cerdan, R, Guichou, J.-F. 登録日 2021-11-26 公開日 2022-12-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors To Be Published

<245246247248249250251252253254255256257258259260>