7QAD

Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with 1,4-Oxazepane hydrochloride

Summary for 7QAD

• Entry DOI: 10.2210/pdb7qad/pdb
• Descriptor: Cholinephosphate cytidylyltransferase, 1,4-oxazepane, Guanidinium, ... (4 entities in total)
• Functional Keywords: plasmodium falciparum cct inhibitors fragments, transferase
• Biological source: Plasmodium falciparum
• Total number of polymer chains: 1
• Total formula weight: 21031.43

Authors

Duclovel, C.,Gelin, M.,Krimm, I.,Cerdan, R.,Guichou, J.-F. (deposition date: 2021-11-16, release date: 2022-11-30, Last modification date: 2024-01-31)

• Primary citation: Duclovel, C.,Gelin, M.,Wein, S.,Wengelnik, K.,Krimm, I.,Guichou, J.F.,Cerdan, R.; Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors.; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.11 Å)