1MFG
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1MFL
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6R1T
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![BU of 6r1t by Molmil](/molmil-images/mine/6r1t) | Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 1, free nuclesome | 分子名称: | DNA (147-MER), HISTONE H2A, Histone H2A, ... | 著者 | Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A. | 登録日 | 2019-03-15 | 公開日 | 2019-04-24 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.02 Å) | 主引用文献 | A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. Cell Rep, 27, 2019
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5HBU
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5HD7
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![BU of 5hd7 by Molmil](/molmil-images/mine/5hd7) | Dissecting Therapeutic Resistance to ERK Inhibition Rat Mutant SCH772984 in complex with (3R)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-N-[3-(pyridin-4-yl)-2H-indazol-5-yl]pyrrolidine-3-carboxamide | 分子名称: | (3R)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-N-[3-(pyridin-4-yl)-2H-indazol-5-yl]pyrrolidine-3-carboxamide, Mitogen-activated protein kinase 1, SULFATE ION | 著者 | Jha, S, Morris, E.J, Hruza, A, Mansueto, M.S, Schroeder, G, Arbanas, J, McMasters, D, Restaino, C.R, Dayananth, R, Black, S, Elsen, N.L, Mannarino, A, Cooper, A, Fawell, S, Zawel, L, Jayaraman, L, Samatar, A.A. | 登録日 | 2016-01-04 | 公開日 | 2016-02-24 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Dissecting Therapeutic Resistance to ERK Inhibition. Mol.Cancer Ther., 15, 2016
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6R1U
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![BU of 6r1u by Molmil](/molmil-images/mine/6r1u) | Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 2 | 分子名称: | DNA (147-MER), FLAVIN-ADENINE DINUCLEOTIDE, Histone H2A, ... | 著者 | Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A. | 登録日 | 2019-03-15 | 公開日 | 2019-04-24 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.36 Å) | 主引用文献 | A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. Cell Rep, 27, 2019
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6R25
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![BU of 6r25 by Molmil](/molmil-images/mine/6r25) | Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 3 | 分子名称: | DNA (147-MER), FLAVIN-ADENINE DINUCLEOTIDE, H2B, ... | 著者 | Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A. | 登録日 | 2019-03-15 | 公開日 | 2019-04-24 | 実験手法 | ELECTRON MICROSCOPY (4.61 Å) | 主引用文献 | A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. Cell Rep, 27, 2019
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1MOT
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![BU of 1mot by Molmil](/molmil-images/mine/1mot) | NMR Structure Of Extended Second Transmembrane Domain Of Glycine Receptor alpha1 Subunit in SDS Micelles | 分子名称: | Glycine Receptor alpha-1 CHAIN | 著者 | Yushmanov, V.E, Mandal, P.K, Liu, Z, Tang, P, Xu, Y. | 登録日 | 2002-09-09 | 公開日 | 2003-09-23 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Structure and Backbone Dynamics of the Extended Second Transmembrane Domain of the Human Neuronal Glycine Receptor Alpha1 Subunit Biochemistry, 42, 2003
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3EN3
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5HF9
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![BU of 5hf9 by Molmil](/molmil-images/mine/5hf9) | Crystal structure of human acetylcholinesterase in complex with paraoxon and HI6 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Franklin, M.F, Rudolph, M.J, Ginter, C, Cassidy, M.S, Cheung, J. | 登録日 | 2016-01-06 | 公開日 | 2016-06-22 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface. Proteins, 84, 2016
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1M2J
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![BU of 1m2j by Molmil](/molmil-images/mine/1m2j) | Sir2 homologue H80N mutant-ADP ribose complex | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Silent Information Regulator 2, ZINC ION | 著者 | Chang, J, Cho, Y. | 登録日 | 2002-06-24 | 公開日 | 2003-04-08 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural basis for the NAD-dependent deacetylase mechanism of Sir2 J.BIOL.CHEM., 277, 2002
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3EI4
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6R8E
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![BU of 6r8e by Molmil](/molmil-images/mine/6r8e) | SC14 G-hairpin | 分子名称: | DNA (5'-D(*GP*TP*GP*TP*GP*TP*GP*GP*GP*TP*GP*TP*GP*T)-3') | 著者 | Lenarcic Zivkovic, M, Trantirek, L, Plavec, J. | 登録日 | 2019-04-01 | 公開日 | 2021-02-03 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Insight into formation propensity of pseudocircular DNA G-hairpins. Nucleic Acids Res., 49, 2021
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6R8Z
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![BU of 6r8z by Molmil](/molmil-images/mine/6r8z) | Cryo-EM structure of NCP_THF2(-1)-UV-DDB | 分子名称: | DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ... | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | 登録日 | 2019-04-02 | 公開日 | 2019-06-12 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting. Nature, 571, 2019
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3E8E
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![BU of 3e8e by Molmil](/molmil-images/mine/3e8e) | Crystal structures of the kinase domain of PKA in complex with ATP-competitive inhibitors | 分子名称: | 4-[2-(4-amino-2,5-dihydro-1,2,5-oxadiazol-3-yl)-6-{[(1S)-3-amino-1-phenylpropyl]oxy}-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol, PKI inhibitor peptide, cAMP-dependent protein kinase catalytic subunit alpha | 著者 | Concha, N.O, Elkins, P.A, Smallwood, A, Ward, P. | 登録日 | 2008-08-19 | 公開日 | 2008-11-18 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Aminofurazans as potent inhibitors of AKT kinase Bioorg.Med.Chem.Lett., 19, 2009
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1MP0
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![BU of 1mp0 by Molmil](/molmil-images/mine/1mp0) | Binary Complex of Human Glutathione-Dependent Formaldehyde Dehydrogenase with NAD(H) | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, POTASSIUM ION, ... | 著者 | Sanghani, P.C, Robinson, H, Hurley, T.D, Bosron, W.F. | 登録日 | 2002-09-10 | 公開日 | 2002-09-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure-function relationships in human Class III alcohol dehydrogenase
(formaldehyde dehydrogenase) Chem.Biol.Interact., 143, 2003
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5HCB
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![BU of 5hcb by Molmil](/molmil-images/mine/5hcb) | Globular Domain of the Entamoeba histolytica calreticulin in complex with glucose | 分子名称: | CALCIUM ION, CHLORIDE ION, Calreticulin, ... | 著者 | Moreau, C.P, Cioci, G, Ianello, M, Laffly, E, Chouquet, A, Ferreira, A, Thielens, N.M, Gaboriaud, C. | 登録日 | 2016-01-04 | 公開日 | 2016-08-31 | 最終更新日 | 2017-08-30 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structures of parasite calreticulins provide insights into their flexibility and dual carbohydrate/peptide-binding properties. IUCrJ, 3, 2016
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1M2H
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![BU of 1m2h by Molmil](/molmil-images/mine/1m2h) | Sir2 homologue S24A mutant-ADP ribose complex | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Silent Information Regulator 2, ZINC ION | 著者 | Chang, J, Cho, Y. | 登録日 | 2002-06-24 | 公開日 | 2003-04-08 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis for the NAD-dependent deacetylase mechanism of Sir2 J.BIOL.CHEM., 277, 2002
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1M2N
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3F05
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3F04
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3F6N
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3DLN
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![BU of 3dln by Molmil](/molmil-images/mine/3dln) | Crystal structure of the binding domain of the AMPA subunit GluR3 bound to glutamate | 分子名称: | GLUTAMIC ACID, Glutamate receptor 3, ZINC ION | 著者 | Ahmed, A.H, Wang, Q, Sondermann, H, Oswald, R.E. | 登録日 | 2008-06-27 | 公開日 | 2008-11-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Structure of the S1S2 glutamate binding domain of GLuR3. Proteins, 75, 2008
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3F01
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1JVA
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![BU of 1jva by Molmil](/molmil-images/mine/1jva) | |