PDB: 658 件ウェブページステータス検索Chemie searchBIRD

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8G61	mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) 分子名称: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... 著者 Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. 登録日 2023-02-14 公開日 2023-04-19 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
7QZ6	Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by 5-fluoroTrp 分子名称: DAUNOMYCIN, Transcriptional regulator, PadR-like family 著者 Thunnissen, A.M.W.H. 登録日 2022-01-30 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
7QZ8	Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by the unnatural amino acid 5,6-difluoroTrp 分子名称: DAUNOMYCIN, Transcriptional regulator, PadR-like family 著者 Thunnissen, A.M.W.H. 登録日 2022-01-30 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
7QZ7	Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by 5,6,7-trifluoroTrp 分子名称: DAUNOMYCIN, Transcriptional regulator, PadR-like family 著者 Thunnissen, A.M.W.H. 登録日 2022-01-30 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
7QZ9	Transcriptional regulator LmrR with Trp-67 and Trp-96 replaced by the unnatural amino acid 5,6-difluoroTrp 分子名称: Transcriptional regulator, PadR-like family 著者 Thunnissen, A.M.W.H. 登録日 2022-01-30 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
7QZ5	Transcriptional regulator LmrR with Trp-67 and Trp-96 replaced by the unnatural amino acid 5-fluoroTrp 分子名称: Transcriptional regulator, PadR-like family 著者 Thunnissen, A.M.W.H. 登録日 2022-01-30 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
6OLI	Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC) 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-16 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OLE	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-16 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OM7	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-18 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OM0	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-17 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OLF	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-16 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
7R4X	Cryo-EM reconstruction of the human 40S ribosomal subunit - Full map 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Pellegrino, S, Dent, K.C, Spikes, T, Warren, A.J. 登録日 2022-02-09 公開日 2023-02-22 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.15 Å) 主引用文献 Cryo-EM reconstruction of the human 40S ribosomal subunit at 2.15 angstrom resolution. Nucleic Acids Res., 51, 2023
6OLZ	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-17 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
8GLP	mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure) 分子名称: 1,4-DIAMINOBUTANE, 18S rRNA, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Watson, Z.L, Altman, R.B, Blanchard, S.C. 登録日 2023-03-22 公開日 2023-04-19 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (1.67 Å) 主引用文献 mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
8G5Z	mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state) 分子名称: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... 著者 Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. 登録日 2023-02-14 公開日 2023-04-19 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.64 Å) 主引用文献 mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
8G6J	mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2) 分子名称: (3R,6R,9S,12S,15S,18S,20R,24aR)-6-[(2S)-butan-2-yl]-3,12-bis[(1R)-1-hydroxy-2-methylpropyl]-8,9,11,17,18-pentamethyl-15-[(2S)-2-methylbutyl]hexadecahydropyrido[1,2-a][1,4,7,10,13,16,19]heptaazacyclohenicosine-1,4,7,10,13,16,19(21H)-heptone, (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 1,4-DIAMINOBUTANE, ... 著者 Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. 登録日 2023-02-15 公開日 2023-04-19 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
8G5Y	mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) 分子名称: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... 著者 Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. 登録日 2023-02-14 公開日 2023-04-19 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.29 Å) 主引用文献 mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
8G60	mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) 分子名称: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... 著者 Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. 登録日 2023-02-14 公開日 2023-04-19 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.54 Å) 主引用文献 mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
6OLG	Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA) 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-16 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
7QP7	Structure of the human 48S initiation complex in closed state (h48S AUG closed) 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N. 登録日 2022-01-03 公開日 2022-05-11 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Res., 50, 2022
7QP6	Structure of the human 48S initiation complex in open state (h48S AUG open) 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N. 登録日 2022-01-03 公開日 2022-05-11 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Res., 50, 2022
6G5I	Cryo-EM structure of a late human pre-40S ribosomal subunit - State R 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. 登録日 2018-03-29 公開日 2018-06-06 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
6G18	Cryo-EM structure of a late human pre-40S ribosomal subunit - State C 分子名称: 40S ribosomal protein S11, 40S ribosomal protein S12, 40S ribosomal protein S13, ... 著者 Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. 登録日 2018-03-20 公開日 2018-06-06 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
6G5H	Cryo-EM structure of a late human pre-40S ribosomal subunit - Mature 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. 登録日 2018-03-29 公開日 2018-06-06 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
6G51	Cryo-EM structure of a late human pre-40S ribosomal subunit - State D 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. 登録日 2018-03-28 公開日 2018-06-06 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018

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