2UZR
 
 | | A transforming mutation in the pleckstrin homology domain of AKT1 in cancer (AKT1-PH_E17K) | | 分子名称: | RAC-alpha serine/threonine-protein kinase | | 著者 | Carpten, J.D, Faber, A.L, Horn, C, Donoho, G.P, Briggs, S.L, Robbins, C.M, Hostetter, G, Boguslawski, S, Moses, T.Y, Savage, S, Uhlik, M, Lin, A, Du, J, Qian, Y.W, Zeckner, D.J, Tucker-Kellogg, G, Touchman, J, Patel, K, Mousses, S, Bittner, M, Schevitz, R, Lai, M.H, Blanchard, K.L, Thomas, J.E. | | 登録日 | 2007-05-01 | | 公開日 | 2007-07-17 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.
Nature, 448, 2007
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2VSG
 | | A Structural Motif in the Variant Surface Glycoproteins of Trypanosoma Brucei | | 分子名称: | VARIANT SURFACE GLYCOPROTEIN ILTAT 1.24 | | 著者 | Blum, M.L, Down, J.A, Metcalf, P, Freymann, D.M, Wiley, D.C. | | 登録日 | 1998-11-19 | | 公開日 | 1998-11-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A structural motif in the variant surface glycoproteins of Trypanosoma brucei.
Nature, 362, 1993
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3XIS
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2X30
 | | Crystal structure of the r139n mutant of a bifunctional enzyme pria | | 分子名称: | PHOSPHORIBOSYL ISOMERASE A, SULFATE ION | | 著者 | Noda-Garcia, L, Camacho-Zarco, A.R, Verdel-Aranda, K, Wright, H, Soberon, X, Fulop, V, Barona-Gomez, F. | | 登録日 | 2010-01-20 | | 公開日 | 2010-02-02 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Identification and Analysis of Residues Contained on Beta --> Alpha Loops of the Dual-Substrate (Betaalpha)(8) Phosphoribosyl Isomerase a (Pria) Specific for its Phosphoribosyl Anthranilate Isomerase Activity.
Protein Sci., 19, 2010
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2XIS
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4AMS
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2UZS
 | | A transforming mutation in the pleckstrin homology domain of AKT1 in cancer (AKT1-PH_E17K) | | 分子名称: | INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, RAC-alpha serine/threonine-protein kinase | | 著者 | Carpten, J.D, Faber, A.L, Horn, C, Donoho, G.P, Briggs, S.L, Robbins, C.M, Hostetter, G, Boguslawski, S, Moses, T.Y, Savage, S, Uhlik, M, Lin, A, Du, J, Qian, Y.W, Zeckner, D.J, Tucker-Kellogg, G, Touchman, J, Patel, K, Mousses, S, Bittner, M, Schevitz, R, Lai, M.H, Blanchard, K.L, Thomas, J.E. | | 登録日 | 2007-05-01 | | 公開日 | 2007-07-17 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.
Nature, 448, 2007
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3L56
 | | Crystal structure of the large c-terminal domain of polymerase basic protein 2 from influenza virus a/viet nam/1203/2004 (h5n1) | | 分子名称: | Polymerase PB2 | | 著者 | Staker, B.L, Edwards, T, Eric, S, Raymond, A, Stewart, L, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | 登録日 | 2009-12-21 | | 公開日 | 2010-03-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Biological and structural characterization of a host-adapting amino acid in influenza virus.
Plos Pathog., 6, 2010
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5WDL
 | | A processive dipeptidyl aminopeptidase secreted from an established commensal bacterium P. distasonis | | 分子名称: | Aminopeptidase C, N-[(3S)-6-carbamimidamido-2-oxohexan-3-yl]glycinamide, POTASSIUM ION | | 著者 | Wolan, D.W, Xu, J.H, Solania, A, Chatterjee, S, Jiang, Z, ODonoghue, A.J. | | 登録日 | 2017-07-05 | | 公開日 | 2018-07-11 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.625 Å) | | 主引用文献 | A Commensal Dipeptidyl Aminopeptidase with Specificity for N-Terminal Glycine Degrades Human-Produced Antimicrobial Peptides in Vitro.
Acs Chem.Biol., 13, 2018
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4AMQ
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5WDK
 | | A processive dipeptidyl aminopeptidase secreted from an established commensal bacterium P. distasonis | | 分子名称: | 5-[(3aS,4R,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-(2-oxopropyl)pentanamide, Aminopeptidase C, POTASSIUM ION | | 著者 | Wolan, D.W, Xu, J.H, Solania, A, Chatterjee, S, Jiang, Z, ODonoghue, A.J. | | 登録日 | 2017-07-05 | | 公開日 | 2018-07-11 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | A Commensal Dipeptidyl Aminopeptidase with Specificity for N-Terminal Glycine Degrades Human-Produced Antimicrobial Peptides in Vitro.
Acs Chem.Biol., 13, 2018
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3LFK
 | | A reported archaeal mechanosensitive channel is a structural homolog of MarR-like transcriptional regulators | | 分子名称: | CITRIC ACID, MarR Like Protein, TVG0766549, ... | | 著者 | Liu, Z, Walton, T.A, Rees, D.C. | | 登録日 | 2010-01-17 | | 公開日 | 2010-04-14 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A reported archaeal mechanosensitive channel is a structural homolog of MarR-like transcriptional regulators.
Protein Sci., 19, 2010
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1OSH
 | | A Chemical, Genetic, and Structural Analysis of the nuclear bile acid receptor FXR | | 分子名称: | Bile acid receptor, METHYL 3-{3-[(CYCLOHEXYLCARBONYL){[4'-(DIMETHYLAMINO)BIPHENYL-4-YL]METHYL}AMINO]PHENYL}ACRYLATE | | 著者 | Downes, M, Verdecia, M.A, Roecker, A.J, Hughes, R, Hogenesch, J.B, Kast-Woelbern, H.R, Bowman, M.E, Ferrer, J.-L, Anisfeld, A.M, Edwards, P.A, Rosenfeld, J.M, Alvarez, J.G.A, Noel, J.P, Nicolaou, K.C, Evans, R.M. | | 登録日 | 2003-03-19 | | 公開日 | 2003-09-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR
Mol.Cell, 11, 2003
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1PY0
 | | Crystal structure of E51C/E54C Psaz from A.faecalis with CLaNP probe | | 分子名称: | 7,10,13-TRI(CARBOXYMETHYL)-5,15-DIOXO-4,7,10,13,16-PENTAAZA-1,19-DITHIANONADECANE, Pseudoazurin, SULFATE ION, ... | | 著者 | Prudencio, M, Rohovec, J, Peters, J.A, Tocheva, E, Boulanger, M.J, Murphy, M.E, Hupkes, H.J, Kosters, W, Impagliazzo, A, Ubbink, M. | | 登録日 | 2003-07-07 | | 公開日 | 2004-12-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A caged lanthanide complex as a paramagnetic shift agent for protein NMR.
Chemistry, 10, 2004
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3LT6
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1QIU
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6I1J
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1ORO
 | | A FLEXIBLE LOOP AT THE DIMER INTERFACE IS A PART OF THE ACTIVE SITE OF THE ADJACENT MONOMER OF ESCHERICHIA COLI OROTATE PHOSPHORIBOSYLTRANSFERASE | | 分子名称: | OROTATE PHOSPHORIBOSYLTRANSFERASE, SULFATE ION | | 著者 | Henriksen, A, Aghajari, N, Jensen, K.F, Gajhede, M. | | 登録日 | 1995-09-11 | | 公開日 | 1996-04-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A flexible loop at the dimer interface is a part of the active site of the adjacent monomer of Escherichia coli orotate phosphoribosyltransferase.
Biochemistry, 35, 1996
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5UHY
 | | A Human Antibody Against Zika Virus Crosslinks the E Protein to Prevent Infection | | 分子名称: | ZV67 Fab chain 1, ZV67 Fab chain 2, envelope protein | | 著者 | Hasan, S.S, Miller, A, Sapparapu, G, Fernandez, E, Klose, T, Long, F, Fokine, A, Porta, J.C, Jiang, W, Diamond, M.S, Crowe Jr, J.E, Kuhn, R.J, Rossmann, M.G. | | 登録日 | 2017-01-12 | | 公開日 | 2017-03-29 | | 最終更新日 | 2019-11-27 | | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | | 主引用文献 | A human antibody against Zika virus crosslinks the E protein to prevent infection.
Nat Commun, 8, 2017
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3J4U
 | | A new topology of the HK97-like fold revealed in Bordetella bacteriophage: non-covalent chainmail secured by jellyrolls | | 分子名称: | cementing protein, major capsid protein | | 著者 | Zhang, X, Guo, H, Jin, L, Czornyj, E, Hodes, A, Hui, W.H, Nieh, A.W, Miller, J.F, Zhou, Z.H. | | 登録日 | 2013-10-09 | | 公開日 | 2013-12-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | A new topology of the HK97-like fold revealed in Bordetella bacteriophage by cryoEM at 3.5 A resolution.
Elife, 2, 2013
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3ZBO
 | | A new family of proteins related to the HEAT-like repeat DNA glycosylases with affinity for branched DNA structures | | 分子名称: | ALKF, CHLORIDE ION | | 著者 | Backe, P.H, Simm, R, Laerdahl, J.K, Dalhus, B, Fagerlund, A, Okstad, O.A, Rognes, T, Alseth, I, Kolsto, A.-B, Bjoras, M. | | 登録日 | 2012-11-12 | | 公開日 | 2013-05-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | A New Family of Proteins Related to the Heat-Like Repeat DNA Glycosylases with Affinity for Branched DNA Structures.
J.Struct.Biol., 183, 2013
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3EIU
 | | A second transient position of ATP on its trail to the nucleotide-binding site of subunit B of the motor protein A1Ao ATP synthase | | 分子名称: | 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, ADENOSINE-5'-TRIPHOSPHATE, V-type ATP synthase beta chain | | 著者 | Manimekalai, S.M.S, Kumar, A, Balakrishna, A.M, Gruber, G. | | 登録日 | 2008-09-17 | | 公開日 | 2009-02-10 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.43 Å) | | 主引用文献 | A second transient position of ATP on its trail to the nucleotide-binding site of subunit B of the motor protein A(1)A(O) ATP synthase
J.Struct.Biol., 166, 2009
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4I3H
 | | A three-gate structure of topoisomerase IV from Streptococcus pneumoniae | | 分子名称: | DNA (5'-D(*CP*AP*AP*AP*GP*GP*CP*GP*GP*TP*AP*AP*TP*AP*CP*GP*GP*TP*TP*AP*TP*CP*CP*AP*CP*AP*GP*AP*AP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*TP*TP*CP*TP*GP*TP*GP*GP*AP*TP*AP*AP*CP*CP*GP*TP*AP*TP*TP*AP*CP*CP*GP*CP*CP*TP*TP*TP*G)-3'), MAGNESIUM ION, ... | | 著者 | Laponogov, I, Veselkov, D.A, Pan, X.-S, Crevel, I, Fisher, L.M, Sanderson, M.R. | | 登録日 | 2012-11-26 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Structure of an 'open' clamp type II topoisomerase-DNA complex provides a mechanism for DNA capture and transport.
Nucleic Acids Res., 41, 2013
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4DJB
 | | A Structural Basis for the Assembly and Functions of a Viral Polymer that Inactivates Multiple Tumor Suppressors | | 分子名称: | E4-ORF3 | | 著者 | Ou, H.D, Kwiatkowski, W, Deerinck, T.J, Noske, A, Blain, K.Y, Land, H.S, Soria, C, Powers, C.J, May, A.P, Shu, X, Tsien, R.Y, Fitzpatrick, J.A.J, Long, J.A, Ellisman, M.H, Choe, S, O'Shea, C.C. | | 登録日 | 2012-02-01 | | 公開日 | 2012-10-31 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.053 Å) | | 主引用文献 | A Structural Basis for the Assembly and Functions of a Viral Polymer that Inactivates Multiple Tumor Suppressors.
Cell(Cambridge,Mass.), 151, 2012
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3FYE
 | | Catalytic core subunits (I and II) of cytochrome c oxidase from Rhodobacter sphaeroides in the reduced state | | 分子名称: | CADMIUM ION, CALCIUM ION, COPPER (I) ION, ... | | 著者 | Qin, L, Mills, D.A, Proshlyakov, D.A, Hiser, C, Ferguson-Miller, S. | | 登録日 | 2009-01-22 | | 公開日 | 2009-06-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Redox dependent conformational changes in cytochrome c oxidase suggest a gating mechanism for proton uptake.
Biochemistry, 48, 2009
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