2Y6G
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![BU of 2y6g by Molmil](/molmil-images/mine/2y6g) | Cellopentaose binding mutated (X-2 L110F) CBM4-2 Carbohydrate Binding Module from a Thermostable Rhodothermus marinus Xylanase | 分子名称: | CALCIUM ION, XYLANASE, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | von Schantz, L, Hakansson, M, Logan, D.T, Walse, B, Osterlin, J, Nordberg-Karlsson, E, Ohlin, M. | 登録日 | 2011-01-21 | 公開日 | 2012-03-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Structural basis for carbohydrate-binding specificity--a comparative assessment of two engineered carbohydrate-binding modules. Glycobiology, 22, 2012
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1WYT
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![BU of 1wyt by Molmil](/molmil-images/mine/1wyt) | Crystal structure of glycine decarboxylase (P-protein) of the glycine cleavage system, in apo form | 分子名称: | glycine dehydrogenase (decarboxylating) subunit 1, glycine dehydrogenase subunit 2 (P-protein) | 著者 | Nakai, T, Nakagawa, N, Maoka, N, Masui, R, Kuramitsu, S, Kamiya, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-02-17 | 公開日 | 2005-04-05 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of P-protein of the glycine cleavage system: implications for nonketotic hyperglycinemia Embo J., 24, 2005
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6XTV
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![BU of 6xtv by Molmil](/molmil-images/mine/6xtv) | FULL-LENGTH LTTR LYSG FROM CORYNEBACTERIUM GLUTAMICUM WITH BOUND EFFECTOR ARG | 分子名称: | ARGININE, Lysine export transcriptional regulatory protein LysG | 著者 | Hofmann, E, Syberg, F, Schlicker, C, Eggeling, L, Schendzielorz, G. | 登録日 | 2020-01-16 | 公開日 | 2020-10-07 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Engineering and application of a biosensor with focused ligand specificity. Nat Commun, 11, 2020
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5XBJ
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6XNT
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![BU of 6xnt by Molmil](/molmil-images/mine/6xnt) | Crystal structure of I91A mutant of human CEACAM1 | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, octyl beta-D-glucopyranoside | 著者 | Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S. | 登録日 | 2020-07-04 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium. Commun Biol, 4, 2021
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6XNW
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![BU of 6xnw by Molmil](/molmil-images/mine/6xnw) | Crystal structure of V39A mutant of human CEACAM1 | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, NICKEL (II) ION | 著者 | Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S. | 登録日 | 2020-07-04 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium. Commun Biol, 4, 2021
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6XO1
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![BU of 6xo1 by Molmil](/molmil-images/mine/6xo1) | Crystal structure of N97A mutant of human CEACAM1 | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, MALONIC ACID | 著者 | Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S. | 登録日 | 2020-07-05 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.758 Å) | 主引用文献 | Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium. Commun Biol, 4, 2021
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6XNO
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![BU of 6xno by Molmil](/molmil-images/mine/6xno) | Crystal structure of E99A mutant of human CEACAM1 | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, MALONIC ACID, octyl beta-D-glucopyranoside | 著者 | Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S. | 登録日 | 2020-07-03 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium. Commun Biol, 4, 2021
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7VSO
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![BU of 7vso by Molmil](/molmil-images/mine/7vso) | Serial Femtosecond Crystallography (SFX) of Ground State Bacteriorhodopsin Crystallized from Bicelles in Complex with HAD16 Determined Using 7-keV X-ray Free Electron Laser (XFEL) at SACLA | 分子名称: | 2-[[(2R)-2-(3-bromanyl-5-iodanyl-phenyl)carbonyloxy-3-tetradecanoyloxy-propoxy]-oxidanyl-phosphoryl]oxyethyl-trimethyl-azanium, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Bacteriorhodopsin, ... | 著者 | Mizohata, E, Nakane, T, Hanashima, S. | 登録日 | 2021-10-27 | 公開日 | 2022-02-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Heavy Atom Detergent/Lipid Combined X-ray Crystallography for Elucidating the Structure-Function Relationships of Membrane Proteins. Membranes (Basel), 11, 2021
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5L6Q
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![BU of 5l6q by Molmil](/molmil-images/mine/5l6q) | Refolded AL protein from cardiac amyloidosis | 分子名称: | CARBONATE ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Annamalai, K, Liberta, F, Vielberg, M.-T, Lilie, H, Guehrs, K.-H, Schierhorn, A, Koehler, R, Schmidt, A, Haupt, C, Hegenbart, O, Schoenland, S, Groll, M, Faendrich, M. | 登録日 | 2016-05-31 | 公開日 | 2017-05-31 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Common Fibril Structures Imply Systemically Conserved Protein Misfolding Pathways In Vivo. Angew. Chem. Int. Ed. Engl., 56, 2017
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7VQS
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![BU of 7vqs by Molmil](/molmil-images/mine/7vqs) | Crystal structure of LSD1 in complex with compound 4 | 分子名称: | 3-[3,5-bis(fluoranyl)-2-[(2-fluoranylpyridin-3-yl)methoxy]phenyl]propanal, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Niwa, H, Koda, Y, Sato, S, Yamamoto, H, Koyama, H, Umehara, T. | 登録日 | 2021-10-20 | 公開日 | 2022-06-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | 主引用文献 | Design and Synthesis of Tranylcypromine-Derived LSD1 Inhibitors with Improved hERG and Microsomal Stability Profiles. Acs Med.Chem.Lett., 13, 2022
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7VQT
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![BU of 7vqt by Molmil](/molmil-images/mine/7vqt) | Crystal structure of LSD1 in complex with compound 5 | 分子名称: | 3-[3,5-bis(fluoranyl)-2-[(2-fluoranylpyridin-4-yl)methoxy]phenyl]propanal, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Niwa, H, Koda, Y, Sato, S, Yamamoto, H, Koyama, H, Umehara, T. | 登録日 | 2021-10-20 | 公開日 | 2022-06-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Design and Synthesis of Tranylcypromine-Derived LSD1 Inhibitors with Improved hERG and Microsomal Stability Profiles. Acs Med.Chem.Lett., 13, 2022
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7VQU
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![BU of 7vqu by Molmil](/molmil-images/mine/7vqu) | Crystal structure of LSD1 in complex with compound S1427 | 分子名称: | 3-[3,5-bis(fluoranyl)-2-[(2-fluoranylpyridin-3-yl)methoxy]phenyl]propanal, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Niwa, H, Koda, Y, Sato, S, Yamamoto, H, Koyama, H, Umehara, T. | 登録日 | 2021-10-20 | 公開日 | 2022-06-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | 主引用文献 | Design and Synthesis of Tranylcypromine-Derived LSD1 Inhibitors with Improved hERG and Microsomal Stability Profiles. Acs Med.Chem.Lett., 13, 2022
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8IV5
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![BU of 8iv5 by Molmil](/molmil-images/mine/8iv5) | Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 8H12 and 1C4 (local refinement) | 分子名称: | Spike protein S1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, heavy chain of 1C4, ... | 著者 | Sun, H, Jiang, Y, Zheng, Q, Li, S, Xia, N. | 登録日 | 2023-03-26 | 公開日 | 2023-08-16 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3.77 Å) | 主引用文献 | Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD. Protein Cell, 15, 2024
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8IVA
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![BU of 8iva by Molmil](/molmil-images/mine/8iva) | Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs XMA01 and 3E2 (local refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, heavy chain of 3E2, ... | 著者 | Sun, H, Jiang, Y, Zheng, Q, Li, S, Xia, N. | 登録日 | 2023-03-26 | 公開日 | 2023-08-16 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3.95 Å) | 主引用文献 | Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD. Protein Cell, 15, 2024
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8IV4
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![BU of 8iv4 by Molmil](/molmil-images/mine/8iv4) | Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 8H12 and 3E2 (local refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, heavy chain of 3E2, ... | 著者 | Sun, H, Jiang, Y, Zheng, Q, Li, S, Xia, N. | 登録日 | 2023-03-26 | 公開日 | 2023-08-16 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD. Protein Cell, 15, 2024
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8IV8
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![BU of 8iv8 by Molmil](/molmil-images/mine/8iv8) | Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 3E2 and 1C4 (local refinement) | 分子名称: | Spike protein S1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, heavy chain of 1C4, ... | 著者 | Sun, H, Jiang, Y, Zheng, Q, Li, S, Xia, N. | 登録日 | 2023-03-26 | 公開日 | 2023-08-16 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | 主引用文献 | Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD. Protein Cell, 15, 2024
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1WYV
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![BU of 1wyv by Molmil](/molmil-images/mine/1wyv) | Crystal structure of glycine decarboxylase (P-protein) of the glycine cleavage system, in inhibitor-bound form | 分子名称: | (AMINOOXY)ACETIC ACID, PYRIDOXAL-5'-PHOSPHATE, glycine dehydrogenase (decarboxylating) subunit 1, ... | 著者 | Nakai, T, Nakagawa, N, Maoka, N, Masui, R, Kuramitsu, S, Kamiya, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-02-17 | 公開日 | 2005-04-05 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of P-protein of the glycine cleavage system: implications for nonketotic hyperglycinemia Embo J., 24, 2005
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7VJT
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![BU of 7vjt by Molmil](/molmil-images/mine/7vjt) | Crystal Structure of Mtb Pks13-TE in complex with inhibitor coumestan derivative 8 | 分子名称: | 3,8-bis(oxidanyl)-7-(piperidin-1-ylmethyl)-[1]benzofuro[3,2-c]chromen-6-one, Polyketide synthase Pks13 (Termination polyketide synthase) | 著者 | Zhang, W, Wang, S.S, Yu, L.F. | 登録日 | 2021-09-28 | 公開日 | 2022-09-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Structure-Based Optimization of Coumestan Derivatives as Polyketide Synthase 13-Thioesterase(Pks13-TE) Inhibitors with Improved hERG Profiles for Mycobacterium tuberculosis Treatment. J.Med.Chem., 65, 2022
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1WUE
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![BU of 1wue by Molmil](/molmil-images/mine/1wue) | Crystal structure of protein GI:29375081, unknown member of enolase superfamily from enterococcus faecalis V583 | 分子名称: | mandelate racemase/muconate lactonizing enzyme family protein | 著者 | Fedorov, A.A, Fedorov, E.V, Yew, W.S, Gerlt, J.A, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2004-12-05 | 公開日 | 2004-12-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family Proc.Natl.Acad.Sci.USA, 111, 2014
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1OVD
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![BU of 1ovd by Molmil](/molmil-images/mine/1ovd) | THE K136E MUTANT OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE A IN COMPLEX WITH OROTATE | 分子名称: | DIHYDROOROTATE DEHYDROGENASE A, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | 著者 | Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S. | 登録日 | 2003-03-26 | 公開日 | 2003-08-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function. J.Biol.Chem., 278, 2003
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7WI0
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![BU of 7wi0 by Molmil](/molmil-images/mine/7wi0) | SARS-CoV-2 Omicron variant spike in complex with three human neutralizing antibodies | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c1437_light_IGLV1-40_IGLJ1, IG c934_light_IGKV1-5_IGKJ1, ... | 著者 | Zheng, Q, Li, S, Sun, H, Zheng, Z, Wang, S. | 登録日 | 2022-01-01 | 公開日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (3.82 Å) | 主引用文献 | Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron. Cell Rep, 39, 2022
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2JHF
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![BU of 2jhf by Molmil](/molmil-images/mine/2jhf) | Structural evidence for a ligand coordination switch in liver alcohol dehydrogenase | 分子名称: | ALCOHOL DEHYDROGENASE E CHAIN, CADMIUM ION, DIMETHYL SULFOXIDE, ... | 著者 | Meijers, R, Adolph, H.W, Dauter, Z, Wilson, K.S, Lamzin, V.S, Cedergren-Zeppezauer, E.S. | 登録日 | 2007-02-22 | 公開日 | 2007-04-24 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Structural Evidence for a Ligand Coordination Switch in Liver Alcohol Dehydrogenase Biochemistry, 46, 2007
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7WHZ
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![BU of 7whz by Molmil](/molmil-images/mine/7whz) | SARS-CoV-2 spike protein in complex with three human neutralizing antibodies | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c1437_light_IGLV1-40_IGLJ1, IG c934_light_IGKV1-5_IGKJ1, ... | 著者 | Zheng, Q, Li, S, Sun, H, Zheng, Z, Wang, S. | 登録日 | 2022-01-01 | 公開日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | 主引用文献 | Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron. Cell Rep, 39, 2022
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3IS4
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![BU of 3is4 by Molmil](/molmil-images/mine/3is4) | Crystal structure of Leishmania mexicana pyruvate kinase (LmPYK)in complex with 1,3,6,8-pyrenetetrasulfonic acid | 分子名称: | GLYCEROL, Pyruvate kinase, pyrene-1,3,6,8-tetrasulfonic acid | 著者 | Walkinshaw, M.D, Morgan, H.P. | 登録日 | 2009-08-25 | 公開日 | 2010-03-23 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | An improved strategy for the crystallization of Leishmania mexicana pyruvate kinase Acta Crystallogr.,Sect.F, 66, 2010
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