1WYV

Crystal structure of glycine decarboxylase (P-protein) of the glycine cleavage system, in inhibitor-bound form

Summary for 1WYV

• Entry DOI: 10.2210/pdb1wyv/pdb
• Related: 1WYT 1WYU
• Descriptor: glycine dehydrogenase (decarboxylating) subunit 1, glycine dehydrogenase subunit 2 (P-protein), PYRIDOXAL-5'-PHOSPHATE, ... (5 entities in total)
• Functional Keywords: alpha(2)beta(2) tetramer, riken structural genomics/proteomics initiative, rsgi, structural genomics, oxidoreductase
• Biological source: Thermus thermophilus; More
• Total number of polymer chains: 8
• Total formula weight: 401164.21

Authors

Nakai, T.,Nakagawa, N.,Maoka, N.,Masui, R.,Kuramitsu, S.,Kamiya, N.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2005-02-17, release date: 2005-04-05, Last modification date: 2024-04-03)

• Primary citation: Nakai, T.,Nakagawa, N.,Maoka, N.,Masui, R.,Kuramitsu, S.,Kamiya, N.; Structure of P-protein of the glycine cleavage system: implications for nonketotic hyperglycinemia; Embo J., 24:1523-1536, 2005; PubMed: 15791207; DOI: 10.1038/sj.emboj.7600632

Experimental method

X-RAY DIFFRACTION (2.4 Å)