PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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4KZP	Crystal Structure of a Putative Short Chain Dehydrogenase from Mycobacterium smegmatis 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Oxidoreductase, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-05-30 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Crystal Structure of a Putative Short Chain Dehydrogenase from Mycobacterium smegmatis To be Published
4KZW	Structure of the carbohydrate-recognition domain of the C-type lectin mincle 分子名称: C-TYPE LECTIN MINCLE, CALCIUM ION, CITRATE ANION, ... 著者 Feinberg, H, Jegouzo, S.A.F, Rowntree, T.J.W, Guan, Y, Brash, M.A, Taylor, M.E, Weis, W.I, Drickamer, K. 登録日 2013-05-30 公開日 2013-08-28 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Mechanism for Recognition of an Unusual Mycobacterial Glycolipid by the Macrophage Receptor Mincle. J.Biol.Chem., 288, 2013
4L1U	Crystal Structure of Human Rtf1 Plus3 Domain in Complex with Spt5 CTR Phosphopeptide 分子名称: GLYCEROL, RNA polymerase-associated protein RTF1 homolog, SULFATE ION, ... 著者 Wier, A.D, Heroux, A, VanDemark, A.P. 登録日 2013-06-03 公開日 2013-10-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.424 Å) 主引用文献 Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin. Proc.Natl.Acad.Sci.USA, 110, 2013
4L46	Crystal structures of human p70S6K1-WT 分子名称: 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, RPS6KB1 protein, SULFATE ION, ... 著者 Wang, J, Zhong, C, Ding, J. 登録日 2013-06-07 公開日 2013-07-24 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif Biochem.J., 454, 2013
4EKV	Streptavidin 8-aa-loop H127C mutein with reversible biotin binding 分子名称: BIOTIN, CHLORIDE ION, Streptavidin 著者 Barrette-Ng, I.H, Honetschlaeger, C, Wong, S.L, Ng, K.K.S. 登録日 2012-04-09 公開日 2012-06-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Development of a tetrameric streptavidin mutein with reversible biotin binding capability: engineering a mobile loop as an exit door for biotin. Plos One, 7, 2012
4L5K	Crystal structure of the complex of DNA hexamer d(CGATCG) with Coptisine 分子名称: 6,7-dihydro[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquino[3,2-a]isoquinolin-5-ium, DNA (5'-D(*CP*GP*AP*TP*CP*G)-3') 著者 Ferraroni, M, Bazzicalupi, C, Gratteri, P. 登録日 2013-06-11 公開日 2014-07-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Crystal structure of the complex of DNA hexamer d(CGATCG) with Coptisine to be published
4L8C	Crystal structure of the H2Db in complex with the NP-N3D peptide 分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... 著者 Rossjohn, J, Gras, S. 登録日 2013-06-16 公開日 2013-10-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Acute emergence and reversion of influenza A virus quasispecies within CD8(+) T cell antigenic peptides. Nat Commun, 4, 2013
4L83	Structure of a putative Ubiquitin-conjugating enzyme E2 from Brugia malayi 分子名称: 1,2-ETHANEDIOL, Ube2i2 protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-06-15 公開日 2013-06-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of a putative Ubiquitin-conjugating enzyme E2 from Brugia malayi TO BE PUBLISHED
4EG6	Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor Chem 1325 分子名称: 4-{4-[(1H-benzimidazol-2-ylmethyl)amino]-6-(2-chloro-4-methoxyphenoxy)pyrimidin-2-yl}piperazin-2-one, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Koh, C.Y, Kim, J.E, Shibata, S, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. 登録日 2012-03-30 公開日 2012-09-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.901 Å) 主引用文献 Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection. Structure, 20, 2012
4ES0	X-ray structure of WDR5-SETd1b Win motif peptide binary complex 分子名称: Histone-lysine N-methyltransferase SETD1B, WD repeat-containing protein 5 著者 Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S. 登録日 2012-04-21 公開日 2012-05-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.817 Å) 主引用文献 Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases. J.Biol.Chem., 287, 2012
4KV9	GTPase domain of Septin 10 from Schistosoma mansoni in complex with GDP 分子名称: GUANOSINE-5'-DIPHOSPHATE, Septin 著者 Zeraik, A.E, Pereira, H.M, Santos, Y.V, Brandao-Neto, J, Garratt, R.C, Araujo, A.P.U, Demarco, R. 登録日 2013-05-22 公開日 2014-02-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Crystal Structure of a Schistosoma mansoni Septin Reveals the Phenomenon of Strand Slippage in Septins Dependent on the Nature of the Bound Nucleotide. J.Biol.Chem., 289, 2014
4EIT	Crystal structure of an enoyl-(acyl carrier protein) reductase from Bartonella henselae 分子名称: Enoyl-[acyl-carrier-protein] reductase [NADH] 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-04-05 公開日 2012-04-18 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of an enoyl-(acyl carrier protein) reductase from Bartonella henselae To be Published
4E56	Crystal Structure of spacer 8aa-shortened cephalosporin acylase mutant 分子名称: CALCIUM ION, Cephalosporin acylase 著者 Yin, J, Zhang, Z, Wu, G, Huang, X. 登録日 2012-03-14 公開日 2013-03-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 spacer shortened Cephalosporin acylase To be Published
4KXM	Crystal structure of DNPH1 (RCL) WITH N6-ISOPENTENYL-AMP 分子名称: 2'-deoxynucleoside 5'-phosphate N-hydrolase 1, N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE 著者 Padilla, A, Labesse, G, Kaminski, P.A. 登録日 2013-05-27 公開日 2014-02-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 N (6)-substituted AMPs inhibit mammalian deoxynucleotide N-hydrolase DNPH1. Plos One, 8, 2013
4KYX	Crystal structure of ADP-ribose pyrophosphatase MutT from Rickettsia felis 分子名称: ADP-ribose pyrophosphatase MutT 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-05-29 公開日 2013-08-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of ADP-ribose pyrophosphatase MutT from Rickettsia felis To be Published
4L0F	Structure of P450sky (CYP163B3), a cytochrome P450 from skyllamycin biosynthesis (open active site) 分子名称: 1,2-ETHANEDIOL, P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Cryle, M.J. 登録日 2013-05-31 公開日 2013-09-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Cytochrome p450sky interacts directly with the nonribosomal Peptide synthetase to generate three amino Acid precursors in skyllamycin biosynthesis. Acs Chem.Biol., 8, 2013
4L23	Crystal Structure of p110alpha complexed with niSH2 of p85alpha and PI-103 分子名称: 3-(4-MORPHOLIN-4-YLPYRIDO[3',2':4,5]FURO[3,2-D]PYRIMIDIN-2-YL)PHENOL, GLYCEROL, Phosphatidylinositol 3-kinase regulatory subunit alpha, ... 著者 Zhang, J, Zhao, Y.L, Chen, Y.Y, Huang, M, Jiang, F. 登録日 2013-06-04 公開日 2014-01-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 Crystal Structures of PI3K alpha Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design. ACS Med Chem Lett, 5, 2014
4E6B	Crystal Structure of statistically disordered 19mer duplex p(CGG)3C(CUG)3 分子名称: 5'-R(P*CP*GP*GP*CP*GP*GP*CP*GP*GP*CP*CP*UP*GP*CP*UP*GP*CP*UP*G)-3' 著者 Malinina, L, Popov, A, Tamjar, J. 登録日 2012-03-15 公開日 2012-07-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Structural dynamics of double-helical RNAs composed of CUG/CUG- and CUG/CGG-repeats. J.Biomol.Struct.Dyn., 30, 2012
4E6I	Crystal structure of Staphylococcal nuclease variant NVIAGA V99G at cryogenic temperature 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHATE ION, Thermonuclease 著者 Doctrow, B.M, Schlessman, J.L, Garcia-Moreno E, B. 登録日 2012-03-15 公開日 2012-04-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Local flexibility as a determinant of pKa values of surface ionizable groups in proteins To be Published
4E71	Crystal structure of the RHO GTPASE binding domain of Plexin B2 分子名称: Plexin-B2, SODIUM ION 著者 Guan, X, Wang, H, Tempel, W, Tong, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) 登録日 2012-03-16 公開日 2012-03-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Crystal structure of the RHO GTPASE binding domain of Plexin B2 to be published
4LAH	Structure-Based Design of New Dihydrofolate Reductase Antibacterial Agents: 7-(Benzimidazol-1-yl)-2,4-diaminoquinazolines 分子名称: 7-[5,6-dimethyl-2-(1,3-thiazol-4-yl)-1H-benzimidazol-1-yl]quinazoline-2,4-diamine, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Hilgers, M.T. 登録日 2013-06-19 公開日 2014-02-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structure-Based Design of New Dihydrofolate Reductase Antibacterial Agents: 7-(Benzimidazol-1-yl)-2,4-diaminoquinazolines. J.Med.Chem., 57, 2014
4E74	Crystal structure of the RHO GTPASE BINDING DOMAIN of Plexin A4A 分子名称: Plexin-A4, UNKNOWN ATOM OR ION 著者 Guan, X, Wang, H, Tempel, W, Dong, A, Tong, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) 登録日 2012-03-16 公開日 2012-03-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Crystal structure of the RHO GTPASE BINDING DOMAIN of Plexin A4A to be published
4E7A	Crystal structure of a product state assembly of HCV NS5B genotype 2a JFH-1 isolate with beta hairpin deletion bound to primer-template RNA with a 2',3'-ddC 分子名称: 5'-R(*CP*AP*UP*GP*GP*C)-D(P*(DOC))-3', RNA-directed RNA polymerase 著者 Edwards, T.E, Mosley, R.T. 登録日 2012-03-16 公開日 2012-04-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of hepatitis C virus polymerase in complex with primer-template RNA. J.Virol., 86, 2012
4LBJ	Crystal structure of Human galectin-3 CRD K176L mutant in complex with LNT 分子名称: CHLORIDE ION, Galectin-3, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose 著者 Bum-Erdene, K, Blanchard, H. 登録日 2013-06-20 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Galectin-3 interactions with glycosphingolipids. J.Mol.Biol., 426, 2014
4E96	Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor PFi-1 分子名称: 1,2-ETHANEDIOL, 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide, Bromodomain-containing protein 4, ... 著者 Filippakopoulos, P, Picaud, S, Felletar, I, Fedorov, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Fish, P, Bunnage, M, Owen, D, Knapp, S, Cook, A, Structural Genomics Consortium (SGC) 登録日 2012-03-20 公開日 2012-04-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Identification of a chemical probe for bromo and extra C-terminal bromodomain inhibition through optimization of a fragment-derived hit. J.Med.Chem., 55, 2012

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