4E6I
Crystal structure of Staphylococcal nuclease variant NVIAGA V99G at cryogenic temperature
Summary for 4E6I
Entry DOI | 10.2210/pdb4e6i/pdb |
Related | 3T16 3U9O |
Descriptor | Thermonuclease, PHOSPHATE ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total) |
Functional Keywords | staphylococcal nuclease, hyperstable variant, hydrolase |
Biological source | Staphylococcus aureus |
Cellular location | Nuclease A: Secreted. Nuclease B: Membrane: P00644 |
Total number of polymer chains | 2 |
Total formula weight | 33689.71 |
Authors | Doctrow, B.M.,Schlessman, J.L.,Garcia-Moreno E., B. (deposition date: 2012-03-15, release date: 2012-04-18, Last modification date: 2023-09-13) |
Primary citation | Doctrow, B.M.,Schlessman, J.L.,Garcia-Moreno E., B.,Baran, K.L.,Chimenti, M.S.,Herbst, K.J.,Fitch, C.A.,Majumdar, A. Local flexibility as a determinant of pKa values of surface ionizable groups in proteins To be Published, |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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