4E6I

Crystal structure of Staphylococcal nuclease variant NVIAGA V99G at cryogenic temperature

Summary for 4E6I

• Entry DOI: 10.2210/pdb4e6i/pdb
• Related: 3T16 3U9O
• Descriptor: Thermonuclease, PHOSPHATE ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
• Functional Keywords: staphylococcal nuclease, hyperstable variant, hydrolase
• Biological source: Staphylococcus aureus
• Cellular location: Nuclease A: Secreted. Nuclease B: Membrane: P00644
• Total number of polymer chains: 2
• Total formula weight: 33689.71

Authors

Doctrow, B.M.,Schlessman, J.L.,Garcia-Moreno E., B. (deposition date: 2012-03-15, release date: 2012-04-18, Last modification date: 2023-09-13)

• Primary citation: Doctrow, B.M.,Schlessman, J.L.,Garcia-Moreno E., B.,Baran, K.L.,Chimenti, M.S.,Herbst, K.J.,Fitch, C.A.,Majumdar, A.; Local flexibility as a determinant of pKa values of surface ionizable groups in proteins; To be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)