4J7Y
 
 | | Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis | | 分子名称: | D-gamma-glutamyl-(Z)-N-(carboxymethylidene)-S-[(2R)-2-hydroxy-4-phenylbutyl]-L-cysteinamide, Leukotriene C4 synthase, NICKEL (II) ION, ... | | 著者 | Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z. | | 登録日 | 2013-02-14 | | 公開日 | 2014-01-01 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.901 Å) | | 主引用文献 | Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
J.Biol.Chem., 289, 2014
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4J8D
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4DVE
 | | Crystal structure at 2.1 A of the S-component for biotin from an ECF-type ABC transporter | | 分子名称: | BIOTIN, Biotin transporter BioY, nonyl beta-D-glucopyranoside | | 著者 | Berntsson, R.P.-A, ter Beek, J, Majsnerowska, M, Duurkens, R, Puri, P, Poolman, B, Slotboom, D.J. | | 登録日 | 2012-02-23 | | 公開日 | 2012-08-29 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structural divergence of paralogous S components from ECF-type ABC transporters.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4J9F
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4DW4
 | | Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with 5'-UMP | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E(rns) glycoprotein, ... | | 著者 | Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A. | | 登録日 | 2012-02-24 | | 公開日 | 2012-05-23 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
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4DWC
 | | Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with Zn ions | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-D-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A. | | 登録日 | 2012-02-24 | | 公開日 | 2012-05-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
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4JDT
 | | Crystal structure of chimeric germ-line precursor of NIH45-46 Fab in complex with gp120 of 93TH057 HIV-1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ... | | 著者 | Scharf, L, Diskin, R, Bjorkman, P.J. | | 登録日 | 2013-02-25 | | 公開日 | 2013-03-20 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.26 Å) | | 主引用文献 | Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4DYW
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4JFE
 | | Preservation of peptide specificity during TCR-MHC contact dominated affinity enhancement of a melanoma-specific TCR | | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | | 著者 | Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K. | | 登録日 | 2013-02-28 | | 公開日 | 2013-05-29 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
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4E0O
 | | SVQIVYK segment from human Tau (305-311) displayed on 54-membered macrocycle scaffold (form III) | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cyclic pseudo-peptide SVQIVYK(ORN)EF(HAO)(4BF)K(ORN), PHOSPHATE ION | | 著者 | Zhao, M, Liu, C, Sawaya, M.R, Eisenberg, D. | | 登録日 | 2012-03-04 | | 公開日 | 2012-12-19 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Out-of-register beta-sheets suggest a pathway to toxic amyloid aggregates.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4JPD
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4DK6
 | | Structure of Editosome protein | | 分子名称: | RNA-editing complex protein MP81, single domain antibody VHH | | 著者 | Park, Y.-J, Hol, W. | | 登録日 | 2012-02-03 | | 公開日 | 2012-07-04 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2.
Nucleic Acids Res., 40, 2012
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4JTK
 | | Crystal structure of R117Q mutant of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis | | 分子名称: | 2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION, SODIUM ION | | 著者 | Allison, T.M, Cochrane, F.C, Jameson, G.B, Parker, E.J. | | 登録日 | 2013-03-23 | | 公開日 | 2013-06-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Examining the Role of Intersubunit Contacts in Catalysis by 3-Deoxy-d-manno-octulosonate 8-Phosphate Synthase.
Biochemistry, 52, 2013
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4DX1
 | | Crystal structure of the human TRPV4 ankyrin repeat domain | | 分子名称: | GLYCEROL, PHOSPHATE ION, Transient receptor potential cation channel subfamily V member 4 | | 著者 | Inada, H, Gaudet, R. | | 登録日 | 2012-02-27 | | 公開日 | 2012-07-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structural and biochemical consequences of disease-causing mutations in the ankyrin repeat domain of the human TRPV4 channel.
Biochemistry, 51, 2012
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4DPP
 | | The structure of dihydrodipicolinate synthase 2 from Arabidopsis thaliana | | 分子名称: | Dihydrodipicolinate synthase 2, chloroplastic, SODIUM ION | | 著者 | Griffin, M.D.W, Billakanti, J.M, Gerrard, J.A, Dobson, R.C.J, Pearce, F.G. | | 登録日 | 2012-02-14 | | 公開日 | 2012-07-18 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana
Plos One, 7, 2012
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4JXU
 | | Structure of aminotransferase ilvE2 from Sinorhizobium meliloti complexed with PLP | | 分子名称: | Putative aminotransferase | | 著者 | Cooper, D.R, Cymborowski, M.T, Majorek, K.A, Niedzialkowska, E, Porebski, P.J, Stead, M, Hammonds, J, Seidel, R, Ahmed, M, Bonanno, J.B, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2013-03-28 | | 公開日 | 2013-05-29 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of aminotransferase ilvE2 from Sinorhizobium meliloti complexed with PLP
To be Published
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4JUK
 | | Crystal structure of H5N1 influenza virus hemagglutinin, clade 2.3.2.1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ... | | 著者 | DuBois, R.M, Zaraket, H, Reddivari, M, Coop, T, Heath, R.J, White, S.W, Russell, C.J. | | 登録日 | 2013-03-25 | | 公開日 | 2014-05-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.7502 Å) | | 主引用文献 | To be published
To be Published
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4JUN
 | | Crystal structure of H5N1 influenza virus hemagglutinin, clade 5 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | DuBois, R.M, Zaraket, H, Reddivari, M, Coop, T, Heath, R.J, White, S.W, Russell, C.J. | | 登録日 | 2013-03-25 | | 公開日 | 2014-05-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3398 Å) | | 主引用文献 | To be published
To be Published
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4JXT
 | | CID of human RPRD1A in complex with a phosphorylated peptide from RPB1-CTD | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, Regulation of nuclear pre-mRNA domain-containing protein 1A, UNKNOWN ATOM OR ION | | 著者 | Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) | | 登録日 | 2013-03-28 | | 公開日 | 2013-11-13 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.
Nat.Struct.Mol.Biol., 21, 2014
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4E2O
 | | Crystal structure of alpha-amylase from Geobacillus thermoleovorans, GTA, complexed with acarbose | | 分子名称: | 6-AMINO-4-HYDROXYMETHYL-CYCLOHEX-4-ENE-1,2,3-TRIOL, Alpha-amylase, CALCIUM ION, ... | | 著者 | Mok, S.C, Teh, A.H, Saito, J.A, Najimudin, N, Alam, M. | | 登録日 | 2012-03-09 | | 公開日 | 2013-03-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.103 Å) | | 主引用文献 | Crystal structure of a compact alpha-amylase from Geobacillus thermoleovorans.
Enzyme.Microb.Technol., 53, 2013
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4JUS
 | | Crystal structure of a fragment of Human HSPB6 | | 分子名称: | GLYCEROL, Heat shock protein beta-6 | | 著者 | Weeks, S.D, Baranova, E.V, Beelen, S, Heirbaut, M, Gusev, N.B, Strelkov, S.V. | | 登録日 | 2013-03-25 | | 公開日 | 2014-02-05 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular structure and dynamics of the dimeric human small heat shock protein HSPB6.
J.Struct.Biol., 185, 2014
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4JZT
 | | Crystal structure of the Bacillus subtilis pyrophosphohydrolase BsRppH (E68A mutant) bound to GTP | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, dGTP pyrophosphohydrolase | | 著者 | Piton, J, Larue, V, Thillier, Y, Dorleans, A, Pellegrini, O, Li de la Sierra-Gallay, I, Vasseur, J.J, Debart, F, Tisne, C, Condon, C. | | 登録日 | 2013-04-03 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4DWS
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4LNH
 | | Crystal structure of uridine phosphorylase from Vibrio fischeri ES114, NYSGRC Target 29520. | | 分子名称: | GLYCEROL, SULFATE ION, Uridine phosphorylase | | 著者 | Malashkevich, V.N, Bonanno, J.B, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2013-07-11 | | 公開日 | 2013-07-24 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of uridine phosphorylase from Vibrio fischeri ES114, NYSGRC Target 29520.
To be Published
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4LAD
 | | Crystal Structure of the Ube2g2:RING-G2BR complex | | 分子名称: | E3 ubiquitin-protein ligase AMFR, OXALATE ION, Ubiquitin-conjugating enzyme E2 G2, ... | | 著者 | Liang, Y.-H, Li, J, Das, R, Byrd, R.A, Ji, X. | | 登録日 | 2013-06-19 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine.
Embo J., 32, 2013
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