PDB: 928 件ウェブページステータス検索Chemie searchBIRD

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7LMA	Tetrahymena telomerase T3D2 structure at 3.3 Angstrom 分子名称: Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... 著者 He, Y, Wang, Y, Liu, B, Helmling, C, Susac, L, Cheng, R, Zhou, Z.H, Feigon, J. 登録日 2021-02-05 公開日 2021-05-12 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structures of telomerase at several steps of telomere repeat synthesis. Nature, 593, 2021
7LRQ	Crystal structure of human SFPQ/NONO heterodimer, conserved DBHS region 分子名称: CHLORIDE ION, Non-POU domain-containing octamer-binding protein, Splicing factor, ... 著者 Marshall, A.C, Bond, C.S, Mohnen, I. 登録日 2021-02-17 公開日 2021-05-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Paraspeckle subnuclear bodies depend on dynamic heterodimerisation of DBHS RNA-binding proteins via their structured domains. J.Biol.Chem., 298, 2022
7LRU	Crystal structure of SFPQ-NONO-SFPQ chimeric protein homodimer 分子名称: Splicing factor, proline- and glutamine-rich,Isoform 2 of Non-POU domain-containing octamer-binding protein,Isoform Short of Splicing factor, proline- and glutamine-rich 著者 Marshall, A.C, Bond, C.S, Mohnen, I, Knott, G.J. 登録日 2021-02-17 公開日 2021-05-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of SFPQ-NONO-SFPQ chimeric protein homodimer To Be Published
7LMB	Tetrahymena telomerase T5D5 structure at 3.8 Angstrom 分子名称: Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... 著者 He, Y, Wang, Y, Liu, B, Helmling, C, Susac, L, Cheng, R, Zhou, Z.H, Feigon, J. 登録日 2021-02-05 公開日 2021-05-12 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structures of telomerase at several steps of telomere repeat synthesis. Nature, 593, 2021
7MI2	Seb1-G476S RNA binding domain 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Rpb7-binding protein seb1 著者 Jacewicz, A, Shuman, S. 登録日 2021-04-16 公開日 2021-07-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Genetic screen for suppression of transcriptional interference identifies a gain-of-function mutation in Pol2 termination factor Seb1. Proc.Natl.Acad.Sci.USA, 118, 2021
8E5T	Yeast co-transcriptional Noc1-Noc2 RNP assembly checkpoint intermediate 分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... 著者 Sanghai, Z.A, Piwowarczyk, R, Vanden Broeck, A, Klinge, S. 登録日 2022-08-22 公開日 2023-04-12 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 A co-transcriptional ribosome assembly checkpoint controls nascent large ribosomal subunit maturation. Nat.Struct.Mol.Biol., 30, 2023
7NAC	State E2 nucleolar 60S ribosomal biogenesis intermediate - Composite model 分子名称: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... 著者 Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. 登録日 2021-06-21 公開日 2022-11-09 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
4YH8	Structure of yeast U2AF complex 分子名称: Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ZINC ION 著者 Yoshida, H, Park, S.Y, Urano, T, Obayashi, E. 登録日 2015-02-27 公開日 2015-08-12 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A novel 3' splice site recognition by the two zinc fingers in the U2AF small subunit. Genes Dev., 29, 2015
5A5U	Structure of mammalian eIF3 in the context of the 43S preinitiation complex 分子名称: EUKARYOTIC INITIATION FACTOR 3, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I 著者 des-Georges, A, Dhote, V, Kuhn, L, Hellen, C.U.T, Pestova, T.V, Frank, J, Hashem, Y. 登録日 2015-06-21 公開日 2015-09-09 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (9 Å) 主引用文献 Structure of Mammalian Eif3 in the Context of the 43S Preinitiation Complex. Nature, 525, 2015
6PAI	Structure of the human DDB1-DDA1-DCAF15 E3 ubiquitin ligase bound to RBM39 and sulfonamide E7820 分子名称: 3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DDB1- and CUL4-associated factor 15, ... 著者 Volkov, O.A, Du, X. 登録日 2019-06-11 公開日 2019-09-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural Basis and Kinetic Pathway of RBM39 Recruitment to DCAF15 by a Sulfonamide Molecular Glue E7820. Structure, 27, 2019
6Q0W	Structure of DDB1-DDA1-DCAF15 complex bound to Indisulam and RBM39 分子名称: DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1, ... 著者 Faust, T, Yoon, H, Nowak, R.P, Donovan, K.A, Li, Z, Cai, Q, Eleuteri, N.A, Zhang, T, Gray, N.S, Fischer, E.S. 登録日 2019-08-02 公開日 2019-11-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15. Nat.Chem.Biol., 16, 2020
6Q0R	Structure of DDB1-DDA1-DCAF15 complex bound to E7820 and RBM39 分子名称: 3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide, DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, ... 著者 Faust, T, Yoon, H, Nowak, R.P, Donovan, K.A, Li, Z, Cai, Q, Eleuteri, N.A, Zhang, T, Gray, N.S, Fischer, E.S. 登録日 2019-08-02 公開日 2019-11-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15. Nat.Chem.Biol., 16, 2020
5VSU	Structure of yeast U6 snRNP with 2'-phosphate terminated U6 RNA 分子名称: Saccharomyces cerevisiae strain T8 chromosome XII sequence, U4/U6 snRNA-associated-splicing factor PRP24, U6 snRNA-associated Sm-like protein LSm2, ... 著者 Montemayor, E.J. 登録日 2017-05-12 公開日 2018-05-09 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Architecture of the U6 snRNP reveals specific recognition of 3'-end processed U6 snRNA. Nat Commun, 9, 2018
6R5K	Cryo-EM structure of a poly(A) RNP bound to the Pan2-Pan3 deadenylase 分子名称: MAGNESIUM ION, PAN2-PAN3 deadenylation complex catalytic subunit PAN2, PAN2-PAN3 deadenylation complex subunit PAN3, ... 著者 Schaefer, I.B, Conti, E. 登録日 2019-03-25 公開日 2019-05-29 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Molecular Basis for poly(A) RNP Architecture and Recognition by the Pan2-Pan3 Deadenylase. Cell, 177, 2019
5IFM	Human NONO (p54nrb) Homodimer 分子名称: CHLORIDE ION, GLYCEROL, Non-POU domain-containing octamer-binding protein, ... 著者 Knott, G.J, Bond, C.S. 登録日 2016-02-26 公開日 2016-11-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A crystallographic study of human NONO (p54(nrb)): overcoming pathological problems with purification, data collection and noncrystallographic symmetry. Acta Crystallogr D Struct Biol, 72, 2016
5IFN	Human PSPC1 Homodimer 分子名称: Paraspeckle component 1 著者 Knott, G.J, Passon, D.M, Bond, C.S. 登録日 2016-02-26 公開日 2017-08-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.17 Å) 主引用文献 Human PSPC1 Homodimer To Be Published
6Q0V	Structure of DDB1-DDA1-DCAF15 complex bound to tasisulam and RBM39 分子名称: DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1, ... 著者 Faust, T, Yoon, H, Nowak, R.P, Donovan, K.A, Li, Z, Cai, Q, Eleuteri, N.A, Zhang, T, Gray, N.S, Fischer, E.S. 登録日 2019-08-02 公開日 2019-11-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15. Nat.Chem.Biol., 16, 2020
5WPA	Structure of human SFPQ/PSPC1 heterodimer 分子名称: Paraspeckle component 1, Splicing factor, proline- and glutamine-rich 著者 Lee, M. 登録日 2017-08-04 公開日 2018-03-21 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Crystal structure of a SFPQ/PSPC1 heterodimer provides insights into preferential heterodimerization of human DBHS family proteins. J. Biol. Chem., 293, 2018
5WU6	Crystal structure of apo human Tut1, form IV 分子名称: MAGNESIUM ION, Speckle targeted PIP5K1A-regulated poly(A) polymerase 著者 Yamashita, S, Tomita, K. 登録日 2016-12-16 公開日 2017-05-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.209 Å) 主引用文献 Crystal structures of U6 snRNA-specific terminal uridylyltransferase Nat Commun, 8, 2017
4CQ1	Crystal structure of the neuronal isoform of PTB 分子名称: CHLORIDE ION, POLYPYRIMIDINE TRACT-BINDING PROTEIN 2, ZINC ION 著者 Joshi, A, Buckroyd, A.N, Curry, S. 登録日 2014-02-10 公開日 2014-02-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Solution and Crystal Structures of a C Terminal Fragment of the Neuronal Isoform of the Polypyrimidine Tract Binding Protein (Nptb) Peerj, 2, 2014
4FXW	Structure of phosphorylated SF1 complex with U2AF65-UHM domain 分子名称: SULFATE ION, Splicing factor 1, Splicing factor U2AF 65 kDa subunit 著者 Wang, W, Bauer, W.J, Wedekind, J.E, Kielkopf, C.L. 登録日 2012-07-03 公開日 2013-01-16 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Structure of Phosphorylated SF1 Bound to U2AF(65) in an Essential Splicing Factor Complex. Structure, 21, 2013
8SGH	Cryo-EM structure of Karyopherin-beta2 bound to HNRNPH2 PY-NLS 分子名称: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed, Transportin-1 著者 Gonzalez, A, Fung, H.Y.J, Chook, Y.M. 登録日 2023-04-12 公開日 2023-06-14 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.17 Å) 主引用文献 A new Karyopherin-beta 2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders. Structure, 31, 2023
8UI0	Structure of poised transcription complex Pol II-DSIF-NELF - pre-translocated 分子名称: DNA, DNA (38-MER), DNA-directed RNA polymerase II subunit E, ... 著者 Vos, S.M, Su, B.G. 登録日 2023-10-09 公開日 2024-03-20 最終更新日 2024-09-11 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing. Mol.Cell, 84, 2024
8UHG	Structure of paused transcription complex Pol II-DSIF-NELF - poised post-translocated 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... 著者 Vos, S.M, Su, B.G. 登録日 2023-10-09 公開日 2024-03-20 最終更新日 2024-04-17 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing. Mol.Cell, 84, 2024
8UHA	Structure of paused transcription complex Pol II-DSIF-NELF - tilted 分子名称: DNA (28-MER), DNA (38-MER), DNA-directed RNA polymerase II subunit E, ... 著者 Vos, S.M, Su, B.G. 登録日 2023-10-08 公開日 2024-03-20 最終更新日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing. Mol.Cell, 84, 2024

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