PDB: 44851 件ウェブページステータス検索Chemie searchBIRD

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8CJS	JzTx-34 toxin peptide W31A mutant 分子名称: Mu-theraphotoxin-Cg1a 著者 Landon, C, Meudal, H. 登録日 2023-02-13 公開日 2023-07-26 実験手法 SOLUTION NMR 主引用文献 Structure-function relationship of new peptides activating human Na v 1.1. Biomed Pharmacother, 165, 2023
8CJQ	JzTx-34 toxin peptide E20A mutant 分子名称: Mu-theraphotoxin-Cg1a 著者 Landon, C, Meudal, H. 登録日 2023-02-13 公開日 2023-07-26 実験手法 SOLUTION NMR 主引用文献 Structure-function relationship of new peptides activating human Na v 1.1. Biomed Pharmacother, 165, 2023
7AWQ	Structure of the thermostabilized EAAT1 cryst-E386Q mutant in complex with L-ASP, sodium ions and the allosteric inhibitor UCPH101 分子名称: 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, ASPARTIC ACID, BARIUM ION, ... 著者 Canul-Tec, J.C, Legrand, P, Reyes, N. 登録日 2020-11-08 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.65 Å) 主引用文献 The ion-coupling mechanism of human excitatory amino acid transporters. Embo J., 41, 2022
7AWM	Structure of the thermostabilized EAAT1 cryst mutant in complex with L-ASP, three sodium ions and the allosteric inhibitor UCPH101 分子名称: 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, ASPARTIC ACID, BARIUM ION, ... 著者 Canul-Tec, J.C, Legrand, P, Reyes, N. 登録日 2020-11-08 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 The ion-coupling mechanism of human excitatory amino acid transporters. Embo J., 41, 2022
4NYO	The 1.8 Angstrom Crystal Structure of the Periplasmic Divalent Cation Tolerance Protein Cuta from Pyrococcus Horikoshii OT3 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Divalent-cation tolerance protein CutA, ... 著者 Bagautdinov, B, Tahirov, T.H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2013-12-11 公開日 2014-01-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The structures of the CutA1 proteins from Thermus thermophilus and Pyrococcus horikoshii: characterization of metal-binding sites and metal-induced assembly ACTA CRYSTALLOGR.,SECT.F, 70, 2014
5HXZ	Structure-function analysis of functionally diverse members of the cyclic amide hydrolase family of Toblerone fold enzymes 分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Barbiturase, CHLORIDE ION, ... 著者 Peat, T.S, Balotra, S, Wilding, M, Newman, J, Scott, C. 登録日 2016-01-31 公開日 2017-02-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes. Appl. Environ. Microbiol., 83, 2017
6O6J	Crystal structure of the LjCASTOR gating ring in the Ca2+ and Na+ condition 分子名称: CALCIUM ION, Ion channel CASTOR, MAGNESIUM ION, ... 著者 Jiang, Y, Kim, S. 登録日 2019-03-06 公開日 2019-09-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Ca2+-regulated Ca2+channels with an RCK gating ring control plant symbiotic associations. Nat Commun, 10, 2019
3I3D	E. COLI (lacZ) BETA-GALACTOSIDASE (M542A) IN COMPLEX WITH IPTG 分子名称: 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ... 著者 Dugdale, M.L, Dymianiw, D, Minhas, B, Huber, R.E. 登録日 2009-06-30 公開日 2010-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Role of Met-542 as a guide for the conformational changes of Phe-601 that occur during the reaction of β-galactosidase (Escherichia coli). Biochem.Cell Biol., 88, 2010
2O4F	Structure of a parallel-stranded guanine tetraplex crystallised with monovalent ions 分子名称: 5'-D(*TP*GP*GP*GP*GP*T)-3', LITHIUM ION, SODIUM ION 著者 Creze, C, Rinaldi, B, Haser, R, Bouvet, P, Gouet, P. 登録日 2006-12-04 公開日 2007-05-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of a d(TGGGGT) quadruplex crystallized in the presence of Li+ ions. Acta Crystallogr.,Sect.D, 63, 2007
3I3B	E.coli (lacz) Beta-Galactosidase (M542A) in Complex with D-Galactopyranosyl-1-on 分子名称: Beta-galactosidase, D-galactonolactone, DIMETHYL SULFOXIDE, ... 著者 Dugdale, M.L, Dymianiw, D, Minhas, B, Huber, R.E. 登録日 2009-06-30 公開日 2010-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Role of Met-542 as a guide for the conformational changes of Phe-601 that occur during the reaction of β-galactosidase (Escherichia coli). Biochem.Cell Biol., 88, 2010
7LW1	Human phosphofructokinase-1 liver type bound to activator NA-11 分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, 6-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Lynch, E.M, Kollman, J.M, Webb, B. 登録日 2021-02-27 公開日 2022-01-26 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Selective activation of PFKL suppresses the phagocytic oxidative burst. Cell, 184, 2021
6V64	Crystal structure of human thrombin bound to ppack with tryptophans replaced by 5-F-tryptophan 分子名称: D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, SODIUM ION, Thrombin heavy chain, ... 著者 Ruben, E.A, Chen, Z, Di Cera, E. 登録日 2019-12-04 公開日 2020-05-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 19F NMR reveals the conformational properties of free thrombin and its zymogen precursor prethrombin-2. J.Biol.Chem., 295, 2020
4H5N	HSC70 NBD with PO4, Na, Cl 分子名称: CHLORIDE ION, GLYCEROL, Heat shock cognate 71 kDa protein, ... 著者 Stec, B. 登録日 2012-09-18 公開日 2014-03-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
2NWX	Crystal structure of GltPh in complex with L-aspartate and sodium ions 分子名称: 425aa long hypothetical proton glutamate symport protein, ASPARTIC ACID, PALMITIC ACID, ... 著者 Gouaux, E, Boudker, O, Ryan, R, Yernool, D, Shimamoto, K. 登録日 2006-11-16 公開日 2007-02-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.29 Å) 主引用文献 Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter. Nature, 445, 2007
4H5R	HSC70 NBD with Na, Cl and glycerol 分子名称: CHLORIDE ION, GLYCEROL, Heat shock cognate 71 kDa protein, ... 著者 Stec, B. 登録日 2012-09-18 公開日 2014-03-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
2PFP	DNA Polymerase lambda in complex with DNA and dCTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA polymerase lambda, Downstream Primer, ... 著者 Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. 登録日 2007-04-05 公開日 2007-05-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Role of the catalytic metal during polymerization by DNA polymerase lambda. DNA Repair, 6, 2007
6ZPL	Inward-open structure of human glycine transporter 1 in complex with a benzoylisoindoline inhibitor, sybody Sb_GlyT1#7 and bound Na and Cl ions. 分子名称: CHLORIDE ION, Endoglucanase H, SODIUM ION, ... 著者 Shahsavar, A, Stohler, P, Bourenkov, G, Zimmermann, I, Siegrist, M, Guba, W, Pinard, E, Sinning, S, Seeger, M.A, Schneider, T.R, Dawson, R.J.P, Nissen, P. 登録日 2020-07-08 公開日 2021-03-17 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.945 Å) 主引用文献 Structural insights into the inhibition of glycine reuptake. Nature, 591, 2021
3KDP	Crystal structure of the sodium-potassium pump 分子名称: CHOLESTEROL, MAGNESIUM ION, Na+/K+ ATPase gamma subunit transcript variant a, ... 著者 Morth, J.P, Pedersen, B.P, Nissen, P. 登録日 2009-10-23 公開日 2010-02-16 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystal structure of the sodium-potassium pump. Nature, 450, 2007
2GP9	Crystal structure of the slow form of thrombin in a self-inhibited conformation 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Prothrombin 著者 Pineda, A, Chen, Z, Mathews, F.S, Di Cera, E. 登録日 2006-04-17 公開日 2006-09-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Crystal structure of thrombin in a self-inhibited conformation. J.Biol.Chem., 281, 2006
5U16	Structure of human MR1-2-OH-1-NA in complex with human MAIT A-F7 TCR 分子名称: 2-hydroxynaphthalene-1-carbaldehyde, Beta-2-microglobulin, CHLORIDE ION, ... 著者 Keller, A.N, Birkinshaw, R.W, Rossjohn, J. 登録日 2016-11-27 公開日 2017-02-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells. Nat. Immunol., 18, 2017
2PGQ	Human thrombin mutant C191A-C220A in complex with the inhibitor PPACK 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Thrombin heavy chain, ... 著者 Bush-Pelc, L.A, Marino, F, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E. 登録日 2007-04-10 公開日 2007-07-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Important role of the cys-191 cys-220 disulfide bond in thrombin function and allostery J.Biol.Chem., 282, 2007
2PFO	DNA Polymerase lambda in complex with DNA and dUPNPP 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DNA polymerase lambda, ... 著者 Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. 登録日 2007-04-05 公開日 2007-05-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Role of the catalytic metal during polymerization by DNA polymerase lambda. DNA Repair, 6, 2007
5NKQ	Crystal structure of a dual topology fluoride ion channel. 分子名称: FLUORIDE ION, Monobody, Putative fluoride ion transporter CrcB, ... 著者 Stockbridge, R, Miller, C, Newstead, S. 登録日 2017-03-31 公開日 2017-04-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Crystal structures of a double-barrelled fluoride ion channel. Nature, 525, 2015
8GNK	CryoEM structure of cytosol-facing, substrate-bound ratGAT1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CHOLESTEROL, ... 著者 Nayak, S.R, Joseph, D, Penmatsa, A. 登録日 2022-08-24 公開日 2023-05-31 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cryo-EM structure of GABA transporter 1 reveals substrate recognition and transport mechanism. Nat.Struct.Mol.Biol., 30, 2023
8D79	Crystal structure of a four-tetrad, parallel, and Na+ stabilized Tetrahymena thermophila telomeric G-quadruplex in complex with N-methyl mesoporphyrin IX 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*T)-3'), N-METHYLMESOPORPHYRIN, ... 著者 Chen, E.V, Beseiso, D, Yatsunyk, L.A. 登録日 2022-06-07 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Biophysical and structural characterization of telomeric G-quadruplexes from Tetrahymena thermophila in complex with N-Methyl Mesoporphyrin IX To Be Published

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