7UV0

Structure of the sodium/iodide symporter (NIS) in complex with iodide and sodium

Summary for 7UV0

• Entry DOI: 10.2210/pdb7uv0/pdb
• EMDB information: 26808
• Descriptor: Sodium/iodide cotransporter, SODIUM ION, IODIDE ION, ... (4 entities in total)
• Functional Keywords: nis, iodide, symporter, cryo-em, transport protein
• Biological source: Rattus norvegicus (Norway rat)
• Total number of polymer chains: 1
• Total formula weight: 74792.30

Authors

Ravera, S.,Nicola, J.P.,Salazar-De Simone, G.,Sigworth, F.,Karakas, E.,Amzel, L.M.,Bianchet, M.,Carrasco, N. (deposition date: 2022-04-29, release date: 2022-12-21, Last modification date: 2023-01-04)

• Primary citation: Ravera, S.,Nicola, J.P.,Salazar-De Simone, G.,Sigworth, F.J.,Karakas, E.,Amzel, L.M.,Bianchet, M.A.,Carrasco, N.; Structural insights into the mechanism of the sodium/iodide symporter.; Nature, 612:795-801, 2022; PubMed: 36517601; DOI: 10.1038/s41586-022-05530-2

Experimental method

ELECTRON MICROSCOPY (3.1 Å)