PDB: 1671 件ウェブページステータス検索Chemie searchBIRD

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7RP4	Crystal structure of KRAS G12C in complex with GNE-1952 分子名称: 1-[4-[6-chloranyl-7-(5-methyl-1~{H}-indazol-4-yl)quinazolin-4-yl]piperazin-1-yl]propan-1-one, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Oh, A, Tam, C, Wang, W. 登録日 2021-08-03 公開日 2022-03-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors. Nat.Biotechnol., 40, 2022
4EE2	Crystal Structure of Anthrax Protective Antigen K446M Mutant to 1.91-A Resolution 分子名称: CALCIUM ION, Protective antigen 著者 Kintzer, A.F, Krantz, B.A. 登録日 2012-03-28 公開日 2012-10-24 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Anthrax toxin protective antigen integrates poly-gamma-D-glutamate and pH signals to sense the optimal environment for channel formation. Proc.Natl.Acad.Sci.USA, 109, 2012
6E7F	Crystal Structure of Human Inositol Polyphosphate Multikinase (IPMK) Catalytic Core Domain 分子名称: Inositol polyphosphate multikinase, SULFATE ION 著者 Blind, R, Seacrist, C. 登録日 2018-07-26 公開日 2018-11-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystallographic and kinetic analyses of human IPMK reveal disordered domains modulate ATP binding and kinase activity. Sci Rep, 8, 2018
3CGU	Crystal Structure of unliganded Argos 分子名称: Protein giant-lens 著者 Klein, D.E, Stayrook, S.E, Lemmon, M.A. 登録日 2008-03-06 公開日 2008-05-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Structural basis for EGFR ligand sequestration by Argos. Nature, 453, 2008
3I2M	The Crystal Structure of PF-8, the DNA Polymerase Accessory Subunit from Kaposi s Sarcoma-Associated Herpesvirus 分子名称: ORF59 著者 Baltz, J.L, Filman, D.J, Ciustea, M, Silverman, J.E.Y, Lautenschlager, C.L, Coen, D.M, Ricciardi, R.P, Hogle, J.M. 登録日 2009-06-29 公開日 2010-05-12 最終更新日 2021-10-13 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 The crystal structure of PF-8, the DNA polymerase accessory subunit from Kaposi's sarcoma-associated herpesvirus. J.Virol., 83, 2009
3HSL	The Crystal Structure of PF-8, the DNA Polymerase Accessory Subunit from Kaposi's Sarcoma-Associated Herpesvirus 分子名称: ORF59 著者 Baltz, J.L, Filman, D.J, Ciustea, M, Silverman, J.E.Y, Lautenschlager, C.L, Coen, D.M, Ricciardi, R.P, Hogle, J.M. 登録日 2009-06-10 公開日 2009-11-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The crystal structure of PF-8, the DNA polymerase accessory subunit from Kaposi's sarcoma-associated herpesvirus. J.Virol., 83, 2009
3MHZ	1.7A structure of 2-fluorohistidine labeled Protective Antigen 分子名称: CALCIUM ION, Protective antigen, TETRAETHYLENE GLYCOL 著者 Lovell, S, Battaile, K.P, Wimalasena, D.S, Janowiak, B.E, Miyagi, M, Sun, J, Hajduch, J, Pooput, C, Kirk, K.L, Bann, J.G. 登録日 2010-04-09 公開日 2010-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Evidence that histidine protonation of receptor-bound anthrax protective antigen is a trigger for pore formation. Biochemistry, 49, 2010
3Q8A	Crystal structure of WT Protective Antigen (pH 5.5) 分子名称: CALCIUM ION, Protective antigen 著者 Rajapaksha, M, Lovell, S, Janowiak, B.E, Andra, K.K, Battaile, K.P, Bann, J.G. 登録日 2011-01-06 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.129 Å) 主引用文献 pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
3Q8B	Crystal structure of WT Protective Antigen (pH 9.0) 分子名称: CALCIUM ION, Protective antigen 著者 Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. 登録日 2011-01-06 公開日 2012-02-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
3Q8E	Crystal structure of Protective Antigen W346F (pH 8.5) 分子名称: CALCIUM ION, Protective antigen 著者 Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. 登録日 2011-01-06 公開日 2012-02-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.098 Å) 主引用文献 pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
2CH7	Crystal structure of the cytoplasmic domain of a bacterial chemoreceptor from Thermotoga maritima 分子名称: LEAD (II) ION, METHYL-ACCEPTING CHEMOTAXIS PROTEIN 著者 Park, S.Y, Bilwes, A.M, Crane, B.R. 登録日 2006-03-13 公開日 2006-04-18 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Reconstruction of the Chemotaxis Receptor-Kinase Assembly Nat.Struct.Mol.Biol., 13, 2006
5X28	Crystal structure of EGFR 696-1022 L858R in complex with SKLB(6) 分子名称: 9-cyclohexyl-N2-[4-(4-methylpiperazin-1-yl)phenyl]-N8-phenyl-purine-2,8-diamine, CHLORIDE ION, Epidermal growth factor receptor 著者 Yun, C.H. 登録日 2017-01-31 公開日 2018-02-07 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.952 Å) 主引用文献 Structural insights into drug development strategy targeting EGFR T790M/C797S. Oncotarget, 9, 2018
5X2C	Crystal structure of EGFR 696-1022 T790M/V948R in complex with SKLB(5) 分子名称: 1,2-ETHANEDIOL, 9-cyclopentyl-N2-[4-(4-methylpiperazin-1-yl)phenyl]-N8-phenyl-purine-2,8-diamine, CHLORIDE ION, ... 著者 Yun, C.H. 登録日 2017-01-31 公開日 2018-02-21 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural insights into drug development strategy targeting EGFR T790M/C797S. Oncotarget, 9, 2018
5X2F	Crystal structure of EGFR 696-1022 T790M/V948R in complex with SKLB(6) 分子名称: 9-cyclohexyl-N2-[4-(4-methylpiperazin-1-yl)phenyl]-N8-phenyl-purine-2,8-diamine, Epidermal growth factor receptor 著者 Yun, C.H. 登録日 2017-01-31 公開日 2018-02-07 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural insights into drug development strategy targeting EGFR T790M/C797S. Oncotarget, 9, 2018
5X27	Crystal structure of EGFR 696-1022 L858R in complex with SKLB(5) 分子名称: 9-cyclopentyl-N2-[4-(4-methylpiperazin-1-yl)phenyl]-N8-phenyl-purine-2,8-diamine, CHLORIDE ION, Epidermal growth factor receptor 著者 Yun, C.H. 登録日 2017-01-31 公開日 2018-02-07 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.952 Å) 主引用文献 Structural insights into drug development strategy targeting EGFR T790M/C797S. Oncotarget, 9, 2018
2CH4	Complex between Bacterial Chemotaxis histidine kinase CheA domains P4 and P5 and receptor-adaptor protein CheW 分子名称: CHEMOTAXIS PROTEIN CHEA, CHEMOTAXIS PROTEIN CHEW, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Park, S.Y, Bilwes, A.M, Crane, B.R. 登録日 2006-03-10 公開日 2006-04-18 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Reconstruction of the Chemotaxis Receptor-Kinase Assembly Nat.Struct.Mol.Biol., 13, 2006
3TEX	Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) to 1.7-A resolution 分子名称: CALCIUM ION, Protective antigen 著者 Feld, G.K, Krantz, B.A. 登録日 2011-08-15 公開日 2011-10-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen. J.Mol.Biol., 415, 2012
3TEW	Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) to 1.45-A resolution 分子名称: 2-METHOXYETHANOL, CALCIUM ION, Protective antigen 著者 Feld, G.K, Krantz, B.A. 登録日 2011-08-15 公開日 2011-10-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen. J.Mol.Biol., 415, 2012
1UL1	Crystal structure of the human FEN1-PCNA complex 分子名称: Flap endonuclease-1, MAGNESIUM ION, Proliferating cell nuclear antigen 著者 Sakurai, S, Kitano, K, Yamaguchi, H, Hamada, K, Okada, K, Fukuda, K, Uchida, M, Ohtsuka, E, Morioka, H, Hakoshima, T. 登録日 2003-09-05 公開日 2005-03-01 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for recruitment of human flap endonuclease 1 to PCNA EMBO J., 24, 2005
5X2A	Crystal structure of EGFR 696-1022 T790M/V948R in complex with SKLB(3) 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Epidermal growth factor receptor, ... 著者 Yun, C.H. 登録日 2017-01-31 公開日 2018-02-07 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural insights into drug development strategy targeting EGFR T790M/C797S. Oncotarget, 9, 2018
3Q8C	Crystal structure of Protective Antigen W346F (pH 5.5) 分子名称: CALCIUM ION, Protective antigen 著者 Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. 登録日 2011-01-06 公開日 2012-02-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
3TEZ	Crystal Structure of Anthrax Protective Antigen Mutant S337C N664C and dithiolacetone modified to 1.8-A resolution 分子名称: 2-METHOXYETHANOL, ACETONE, CALCIUM ION, ... 著者 Feld, G.K, Krantz, B.A. 登録日 2011-08-15 公開日 2011-10-26 最終更新日 2012-05-23 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen. J.Mol.Biol., 415, 2012
3TEY	Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) Mutant S337C N664C to 2.06-A resolution 分子名称: CALCIUM ION, Protective antigen 著者 Feld, G.K, Krantz, B.A. 登録日 2011-08-15 公開日 2011-10-26 最終更新日 2012-05-23 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen. J.Mol.Biol., 415, 2012
5X26	Crystal structure of EGFR 696-1022 L858R in complex with SKLB(3) 分子名称: CHLORIDE ION, Epidermal growth factor receptor, N2-[4-(4-methylpiperazin-1-yl)phenyl]-N8-phenyl-9-propan-2-yl-purine-2,8-diamine 著者 Yun, C.H. 登録日 2017-01-31 公開日 2018-02-07 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.951 Å) 主引用文献 Structural insights into drug development strategy targeting EGFR T790M/C797S. Oncotarget, 9, 2018
5X2K	Crystal structure of EGFR 696-1022 T790M in complex with WZ4003 分子名称: Epidermal growth factor receptor, N-{3-[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide 著者 Zhu, S.J, Zhao, P, Yun, C.H. 登録日 2017-02-01 公開日 2018-02-21 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (3.201 Å) 主引用文献 Structural insights into drug development strategy targeting EGFR T790M/C797S. Oncotarget, 9, 2018

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