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2KQG
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A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics
分子名称: 5'-D(*CP*GP*GP*GP*CP*GP*GP*GP*CP*AP*CP*GP*AP*GP*GP*GP*AP*GP*GP*GP*T)-3', POTASSIUM ION
著者Hsu, S.-T.D, Varnai, P, Bugaut, A, Reszka, A.P, Neidle, S, Balasubramanian, S.
登録日2009-11-05
公開日2009-11-24
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics
J.Am.Chem.Soc., 131, 2009
2KLA
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NMR STRUCTURE OF A PUTATIVE DINITROGENASE (MJ0327) FROM METHANOCOCCUS JANNASCHII
分子名称: Uncharacterized protein MJ0327
著者Jaudzems, K, Mohanty, B, Geralt, M, Serrano, P, Wilson, I, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
登録日2009-06-30
公開日2009-08-11
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献NMR structure of the protein NP_247299.1: comparison with the crystal structure.
Acta Crystallogr.,Sect.F, 66, 2010
1THE
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CRYSTAL STRUCTURES OF RECOMBINANT RAT CATHEPSIN B AND A CATHEPSIN B-INHIBITOR COMPLEX: IMPLICATIONS FOR STRUCTURE-BASED INHIBITOR DESIGN
分子名称: Cathepsin B, amino{[(4S)-4-{[(benzyloxy)carbonyl]amino}-5-{[(2S)-1-(benzyloxy)-4-chloro-3-oxobutan-2-yl]amino}-5-oxopentyl]amino}met haniminium
著者Huber, C.P, Jia, Z.
登録日1995-09-15
公開日1996-03-10
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of recombinant rat cathepsin B and a cathepsin B-inhibitor complex. Implications for structure-based inhibitor design.
J.Biol.Chem., 270, 1995
2HF0
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Bifidobacterium longum bile salt hydrolase
分子名称: Bile salt hydrolase
著者Suresh, C.G, Kumar, R.S, Brannigan, J.A.
登録日2006-06-22
公開日2006-09-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Functional Analysis of a Conjugated Bile Salt Hydrolase from Bifidobacterium longum Reveals an Evolutionary Relationship with Penicillin V Acylase.
J.Biol.Chem., 281, 2006
1W2K
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tf7a_4380 complex
分子名称: (2R)-2-({4-[AMINO(IMINO)METHYL]PHENYL}AMINO)-N-BENZYL-2-(3,4-DIMETHOXYPHENYL)ACETAMIDE, BLOOD COAGULATION FACTOR VIIA, CACODYLATE ION, ...
著者Banner, D.W, D'Arcy, A, Groebke-Zbinden, K, Ackermann, J, Kirchhofer, D, Ji, Y.-H, Tschopp, T.B, Wallbaum, S, Weber, L.
登録日2004-07-06
公開日2005-06-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Design of Selective Phenylglycine Amide Tissue Factor/Factor Viia Inhibitors
Bioorg.Med.Chem.Lett., 15, 2005
2HCI
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Structure of Human Mip-3a Chemokine
分子名称: DI(HYDROXYETHYL)ETHER, SULFATE ION, SULFITE ION, ...
著者Malik, Z.A, Tack, B.F.
登録日2006-06-16
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structure of human MIP-3alpha chemokine.
Acta Crystallogr.,Sect.F, 62, 2006
2GKT
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Crystal structure of the P14'-Ala32 variant of the N-terminally truncated OMTKY3-del(1-5)
分子名称: Ovomucoid
著者Lee, T.W, Qasim, M.A, Laskowski Jr, M, James, M.N.G.
登録日2006-04-03
公開日2007-02-13
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Structural Insights into the Non-additivity Effects in the Sequence-to-Reactivity Algorithm for Serine Peptidases and their Inhibitors.
J.Mol.Biol., 367, 2007
2GKV
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Crystal structure of the SGPB:P14'-Ala32 OMTKY3-del(1-5) complex
分子名称: Ovomucoid, Streptogrisin B
著者Lee, T.W, Qasim, M.A, Laskowski Jr, M, James, M.N.G.
登録日2006-04-03
公開日2007-02-13
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Insights into the Non-additivity Effects in the Sequence-to-Reactivity Algorithm for Serine Peptidases and their Inhibitors.
J.Mol.Biol., 367, 2007
1SU5
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Understanding protein lids: Structural analysis of active hinge mutants in triosephosphate isomerase
分子名称: 2-PHOSPHOGLYCOLIC ACID, GLYCEROL, SULFATE ION, ...
著者Kursula, I, Salin, M, Sun, J, Norledge, B.V, Haapalainen, A.M, Sampson, N.S, Wierenga, R.K.
登録日2004-03-26
公開日2004-08-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase
Protein Eng.Des.Sel., 17, 2004
1SW7
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Triosephosphate isomerase from Gallus gallus, loop 6 mutant K174N, T175S, A176S
分子名称: 2-PHOSPHOGLYCOLIC ACID, Triosephosphate isomerase
著者Kursula, I, Salin, M, Sun, J, Norledge, B.V, Haapalainen, A.M, Sampson, N.S, Wierenga, R.K.
登録日2004-03-30
公開日2004-08-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase
Protein Eng.Des.Sel., 17, 2004
2KSM
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Central B domain of Rv0899 from Mycobacterium tuberculosis
分子名称: MYCOBACTERIUM TUBERCULOSIS RV0899/MT0922/OmpATb
著者Teriete, P, Yao, Y, Kolodzik, A, Yu, J, Song, H, Niederweis, M, Marassi, F.M.
登録日2010-01-07
公開日2010-02-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Mycobacterium tuberculosis Rv0899 adopts a mixed alpha/beta-structure and does not form a transmembrane beta-barrel.
Biochemistry, 49, 2010
1W0Y
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tf7a_3771 complex
分子名称: 4-(4-BENZYLOXY-2-METHANESULFONYLAMINO-5-METHOXY-BENZYLAMINO)-BENZAMIDINE, BLOOD COAGULATION FACTOR VIIA, CACODYLATE ION, ...
著者Banner, D.W, D'Arcy, A, Groebke-Zbinden, K, Ackermann, J, Kirchhofer, D, Ji, Y.-H, Tschopp, T.B, Wallbaum, S, Weber, L.
登録日2004-05-27
公開日2005-01-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Design of Selective Phenylglycine Amide Tissue Factor/Factor Viia Inhibitors
Bioorg.Med.Chem.Lett., 15, 2005
2KWF
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The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1
分子名称: CREB-binding protein, Transcription factor 4
著者Denis, C.M, Chitayat, S, Plevin, M.J, Liu, S, Spencer, H.L, Ikura, M, LeBrun, D.P, Smith, S.P.
登録日2010-04-08
公開日2011-07-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1
To be Published
2KVN
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Phi29 E-loop hairpin
分子名称: RNA (5'-R(*GP*GP*UP*GP*AP*UP*UP*GP*AP*GP*UP*UP*CP*AP*CP*CP*A)-3')
著者Harris, S.M, Schroeder, S.J.
登録日2010-03-19
公開日2010-07-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Nuclear magnetic resonance structure of the prohead RNA E-loop hairpin.
Biochemistry, 49, 2010
1W0V
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Crystal Structure Of HLA-B*2705 Complexed With the self-Peptide TIS from EGF-response factor 1
分子名称: BETA-2-MICROGLOBULIN, BUTYRATE RESPONSE FACTOR 2, GLYCEROL, ...
著者Hulsmeyer, M, Fiorillo, M.T, Bettosini, F, Sorrentino, R, Saenger, W, Ziegler, A, Uchanska-Ziegler, B.
登録日2004-06-14
公開日2005-03-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Thermodynamic and Structural Equivalence of Two Hla-B27 Subtypes Complexed with a Self-Peptide
J.Mol.Biol., 346, 2005
1W17
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Structure of Bacillus subtilis PdaA, a family 4 Carbohydrate esterase.
分子名称: PROBABLE POLYSACCHARIDE DEACETYLASE PDAA
著者Blair, D.E, van Aalten, D.M.F.
登録日2004-06-17
公開日2005-01-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of Bacillus subtilis PdaA, a family 4 carbohydrate esterase, and a complex with N-acetyl-glucosamine.
FEBS Lett., 570, 2004
2HHI
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The solution structure of antigen MPT64 from Mycobacterium tuberculosis defines a novel class of beta-grasp proteins
分子名称: Immunogenic protein MPT64
著者Wang, Z, Potter, B.M, Gray, A.M, Sacksteder, K.A, Geisbrecht, B.V, Laity, J.H.
登録日2006-06-28
公開日2006-12-05
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The Solution Structure of Antigen MPT64 from Mycobacterium tuberculosis Defines a New Family of Beta-Grasp Proteins.
J.Mol.Biol., 366, 2007
1TJI
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Crystal Structure of the broadly neutralizing anti-HIV-1 antibody 2F5 in complex with a gp41 17mer epitope
分子名称: 1,2-ETHANEDIOL, Envelope Glycoprotein GP41, ISOPROPYL ALCOHOL, ...
著者Ofek, G, Tang, M, Sambor, A, Katinger, H, Mascola, J.R, Wyatt, R, Kwong, P.D.
登録日2004-06-04
公開日2004-10-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and mechanistic analysis of the Anti-Human Immunodeficiency Virus type 1 antibody 2F5 in complex with its gp41 epitope
J.Virol., 78, 2004
2HSP
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SOLUTION STRUCTURE OF THE SH3 DOMAIN OF PHOSPHOLIPASE CGAMMA
分子名称: PHOSPHOLIPASE C-GAMMA (SH3 DOMAIN)
著者Kohda, D, Hatanaka, H, Odaka, M, Inagaki, F.
登録日1994-06-13
公開日1994-08-31
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of the SH3 domain of phospholipase C-gamma.
Cell(Cambridge,Mass.), 72, 1993
1VJA
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Urokinase Plasminogen Activator B-Chain-JT463 Complex
分子名称: N-(BENZYLSULFONYL)SERYL-N~1~-{4-[(Z)-AMINO(IMINO)METHYL]BENZYL}SERINAMIDE, SULFATE ION, plasminogen activator, ...
著者Schweinitz, A, Steinmetzer, T, Banke, I.J, Arlt, M.J.E, Stuerzebecher, A, Schuster, O, Geissler, A, Giersiefen, H, Zeslawska, E, Jacob, U, Kruger, A, Stuerzebecher, J.
登録日2004-02-03
公開日2004-06-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents
J.Biol.Chem., 279, 2004
1SDL
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CROSS-LINKED, CARBONMONOXY HEMOGLOBIN A
分子名称: 1,3,5-BENZENETRICARBOXYLIC ACID, CARBON MONOXIDE, HEMOGLOBIN A, ...
著者Schumacher, M.A, Dixon, M.M, Kluger, R, Jones, R.T, Brennan, R.G.
登録日1996-02-26
公開日1996-08-01
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Allosteric transition intermediates modelled by crosslinked haemoglobins.
Nature, 375, 1995
2HUW
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X-ray crystal structure of the Grb2 SH2 domain complexed to a constrained and cyclopropane-derived ligand
分子名称: Growth factor receptor-bound protein 2, N-({(1R,2R,3S)-2-(methylcarbamoyl)-3-[4-(phosphonooxy)phenyl]cyclopropyl}carbonyl)-L-valyl-L-aspartamide, PHOSPHATE ION
著者Benfield, A.P, Martin, S.F.
登録日2006-07-27
公開日2006-08-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ligand Preorganization May Be Accompanied by Entropic Penalties in Protein-Ligand Interactions.
Angew.Chem.Int.Ed.Engl., 45, 2006
1SSG
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Understanding protein lids: Structural analysis of active hinge mutants in triosephosphate isomerase
分子名称: 2-PHOSPHOGLYCOLIC ACID, GLYCEROL, SULFATE ION, ...
著者Kursula, I, Salin, M, Sun, J, Norledge, B.V, Haapalainen, A.M, Sampson, N.S, Wierenga, R.K.
登録日2004-03-24
公開日2004-08-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase
Protein Eng.Des.Sel., 17, 2004
2KHS
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Solution structure of SNase121:SNase(111-143) complex
分子名称: Nuclease, Thermonuclease
著者Geng, Y, Feng, Y, Xie, T, Shan, L, Wang, J.
登録日2009-04-10
公開日2009-10-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The native-like interactions between SNase121 and SNase(111-143) fragments induce the recovery of their native-like structures and the ability to degrade DNA.
Biochemistry, 48, 2009
2K72
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Solution NMR structure of toxin-like potassium channel blocking domain in MMP23
分子名称: Matrix metalloproteinase-23
著者Khoo, K.K, Feng, Z, Norton, R.S.
登録日2008-07-31
公開日2010-01-05
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Potassium channel modulation by a toxin domain in matrix metalloprotease 23.
J.Biol.Chem., 285, 2010

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