PDB: 36667 件ウェブページステータス検索Chemie searchBIRD

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7VDP	The structure of cyclin-dependent kinase 5 (CDK5) in complex with p25 and Compound 1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Cyclin-dependent kinase 5 activator 1, ... 著者 Malojcic, G, Clugston, S.L, Daniels, M, Harmange, J.C, Ledeborer, M. 登録日 2021-09-07 公開日 2022-03-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Discovery and Optimization of Highly Selective Inhibitors of CDK5. J.Med.Chem., 65, 2022
7VDU	The structure of cyclin-dependent kinase 2 (CDK2) in complex with Compound 1 分子名称: Cyclin-dependent kinase 2, [1-[3-fluoranyl-4-[(2-piperidin-4-yloxy-1,6-naphthyridin-7-yl)amino]phenyl]pyrazol-3-yl]methanol 著者 Malojcic, G, Clugston, S.L, Daniels, M, Harmange, J.C, Ledeborer, M. 登録日 2021-09-07 公開日 2022-03-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Discovery and Optimization of Highly Selective Inhibitors of CDK5. J.Med.Chem., 65, 2022
7VE2	Crystal Structure of Lopinavir bound Plasmepsin II (PMII) from Plasmodium falciparum 分子名称: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE, Plasmepsin II 著者 Mishra, V, Rathore, I, Bhaumik, P. 登録日 2021-09-07 公開日 2023-02-01 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Inhibition of Plasmodium falciparum plasmepsins by drugs targeting HIV-1 protease: A way forward for antimalarial drug discovery. Curr Res Struct Biol, 7, 2024
7VE0	Crystal Structure of Ritonavir bound Plasmepsin II (PMII) from Plasmodium falciparum 分子名称: 1,2-ETHANEDIOL, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Plasmepsin II, ... 著者 Mishra, V, Rathore, I, Bhaumik, P. 登録日 2021-09-07 公開日 2023-02-01 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Inhibition of Plasmodium falciparum plasmepsins by drugs targeting HIV-1 protease: A way forward for antimalarial drug discovery. Curr Res Struct Biol, 7, 2024
7S3I	Ex4-D-Ala bound to the glucagon-like peptide-1 receptor/g protein complex (conformer 2) 分子名称: Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Belousoff, M.J, Piper, S.J, Danev, R. 登録日 2021-09-07 公開日 2022-01-05 最終更新日 2022-03-16 実験手法 ELECTRON MICROSCOPY (2.51 Å) 主引用文献 Structural and functional diversity among agonist-bound states of the GLP-1 receptor. Nat.Chem.Biol., 18, 2022
7VDN	High resolution crystal structure of Sperm Whale Myoglobin in the carbonmonoxy form 分子名称: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Shibayama, N, Sato-Tomita, A, Ishimoto, N, Park, S.Y. 登録日 2021-09-07 公開日 2022-09-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (0.93 Å) 主引用文献 X-ray fluorescence holography of biological metal sites: Application to myoglobin. Biochem.Biophys.Res.Commun., 635, 2022
7VDM	Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with substance P 分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Li, Y, Yang, F. 登録日 2021-09-07 公開日 2021-12-01 最終更新日 2022-07-20 実験手法 ELECTRON MICROSCOPY (2.98 Å) 主引用文献 Structure, function and pharmacology of human itch receptor complexes. Nature, 600, 2021
7VDL	Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with circular cortistatin-14 分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Li, Y, Yang, F. 登録日 2021-09-07 公開日 2021-12-01 最終更新日 2022-07-20 実験手法 ELECTRON MICROSCOPY (3.22 Å) 主引用文献 Structure, function and pharmacology of human itch receptor complexes. Nature, 600, 2021
7VDH	Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with C48/80, state2 分子名称: 2-[4-methoxy-3-[[2-methoxy-3-[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-5-[2-(methylamino)ethyl]phenyl]methyl]phenyl]-~{N}-methyl-ethanamine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Li, Y, Yang, F. 登録日 2021-09-07 公開日 2021-12-01 最終更新日 2022-07-20 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structure, function and pharmacology of human itch receptor complexes. Nature, 600, 2021
7VDE	3.6 A structure of the human hemoglobin 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE 著者 Fan, H.C, Zhang, Y, Sun, F. 登録日 2021-09-06 公開日 2021-12-29 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 A cryo-electron microscopy support film formed by 2D crystals of hydrophobin HFBI. Nat Commun, 12, 2021
7PNF	VWF Tubules of D1D2D'D3 domains 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Javitt, G, Fass, D. 登録日 2021-09-06 公開日 2022-02-23 最終更新日 2022-05-25 実験手法 ELECTRON MICROSCOPY (4.35 Å) 主引用文献 Helical self-assembly of a mucin segment suggests an evolutionary origin for von Willebrand factor tubules. Proc.Natl.Acad.Sci.USA, 119, 2022
7S3B	Crystal structure of intact U2AF65 RRM-region bound to AdML-G5 oligonucleotide 分子名称: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(P*UP*UP*(UD)P*GP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit 著者 Jenkins, J.L, Henderson, S, Kielkopf, C.L. 登録日 2021-09-05 公開日 2022-05-25 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal. Nucleic Acids Res., 50, 2022
7S3C	Crystal structure of intact U2AF65 RRM-region bound to AdML-A5 oligonucleotide 分子名称: DNA/RNA (5'-R(P*UP*UP*(UD)P*AP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit 著者 Glasser, E, Jenkins, J.L, Kielkopf, C.L. 登録日 2021-09-05 公開日 2022-05-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal. Nucleic Acids Res., 50, 2022
7S3A	Crystal structure of intact U2AF65 RRM-region bound to AdML-C5 oligonucleotide 分子名称: DNA/RNA (5'-R(P*UP*UP*(UD)P*CP*U)-D(P*(BRU))-R(P*CP*C)-3'), SODIUM ION, Splicing factor U2AF 65 kDa subunit 著者 Jenkins, J.L, Henderson, S, Kielkopf, C.L. 登録日 2021-09-05 公開日 2022-05-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal. Nucleic Acids Res., 50, 2022
7VCU	Human p97 double hexamer conformer I with D1-ATPgammaS and D2-ADP bound 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. 登録日 2021-09-04 公開日 2022-03-02 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.15 Å) 主引用文献 Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state. Cell Discov, 8, 2022
7VCT	Human p97 single hexamer conformer III with D1-ATPgammaS and D2-ADP bound 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. 登録日 2021-09-04 公開日 2022-03-02 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.21 Å) 主引用文献 Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state. Cell Discov, 8, 2022
7S30	Crystal structure of hen egg white lysozyme 分子名称: Lysozyme C, SODIUM ION 著者 Lima, L.M.T.R, Ramos, N.G. 登録日 2021-09-04 公開日 2022-07-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The reproducible normality of the crystallographic B-factor. Anal.Biochem., 645, 2022
7S33	Crystal structure of hen egg white lysozyme 分子名称: Lysozyme C, SODIUM ION 著者 Lima, L.M.T.R, Ramos, N.G. 登録日 2021-09-04 公開日 2022-07-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The reproducible normality of the crystallographic B-factor. Anal.Biochem., 645, 2022
7S32	Crystal structure of hen egg white lysozyme 分子名称: Lysozyme C, SODIUM ION 著者 Lima, L.M.T.R, Ramos, N.G. 登録日 2021-09-04 公開日 2022-07-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The reproducible normality of the crystallographic B-factor. Anal.Biochem., 645, 2022
7S35	Crystal structure of hen egg white lysozyme 分子名称: Lysozyme C, SODIUM ION 著者 Lima, L.M.T.R, Ramos, N.G. 登録日 2021-09-04 公開日 2022-07-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The reproducible normality of the crystallographic B-factor. Anal.Biochem., 645, 2022
7S34	Crystal structure of hen egg white lysozyme 分子名称: Lysozyme C, SODIUM ION 著者 Lima, L.M.T.R, Ramos, N.G. 登録日 2021-09-04 公開日 2022-07-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The reproducible normality of the crystallographic B-factor. Anal.Biochem., 645, 2022
7S31	Crystal structure of hen egg white lysozyme 分子名称: Lysozyme C, SODIUM ION 著者 Lima, L.M.T.R, Ramos, N.G. 登録日 2021-09-04 公開日 2022-07-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The reproducible normality of the crystallographic B-factor. Anal.Biochem., 645, 2022
7VCX	Human p97 single hexamer conformer II with ATPgammaS bound 分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase 著者 Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. 登録日 2021-09-04 公開日 2022-03-02 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.24 Å) 主引用文献 Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state. Cell Discov, 8, 2022
7VCV	Human p97 single hexamer conformer I with ATPgammaS bound 分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase 著者 Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. 登録日 2021-09-04 公開日 2022-03-02 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.21 Å) 主引用文献 Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state. Cell Discov, 8, 2022
7S2V	Crystal structure of hen egg white lysozyme 分子名称: Lysozyme C, SODIUM ION 著者 Lima, L.M.T.R, Ramos, N.G. 登録日 2021-09-03 公開日 2022-09-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The reproducible normality of the crystallographic B-factor. Anal.Biochem., 645, 2022

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