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7QO5
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26S proteasome Rpt1-RK -Ubp6-UbVS complex in the si state
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ...
著者Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, T.C, Joshi, T, Rudack, T, Sakata, E, Finley, D.
登録日2021-12-23
公開日2022-03-16
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Allosteric control of Ubp6 and the proteasome via a bidirectional switch.
Nat Commun, 13, 2022
4CR4
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Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome
分子名称: 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ...
著者Unverdorben, P, Beck, F, Sledz, P, Schweitzer, A, Pfeifer, G, Plitzko, J.M, Baumeister, W, Foerster, F.
登録日2014-02-25
公開日2014-04-02
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (8.8 Å)
主引用文献Deep Classification of a Large Cryo-Em Dataset Defines the Conformational Landscape of the 26S Proteasome.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CR3
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Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome
分子名称: 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ...
著者Unverdorben, P, Beck, F, Sledz, P, Schweitzer, A, Pfeifer, G, Plitzko, J.M, Baumeister, W, Foerster, F.
登録日2014-02-25
公開日2014-04-02
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (9.3 Å)
主引用文献Deep Classification of a Large Cryo-Em Dataset Defines the Conformational Landscape of the 26S Proteasome.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CR2
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Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome
分子名称: 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ...
著者Unverdorben, P, Beck, F, Sledz, P, Schweitzer, A, Pfeifer, G, Plitzko, J.M, Baumeister, W, Foerster, F.
登録日2014-02-25
公開日2014-04-02
最終更新日2018-10-03
実験手法ELECTRON MICROSCOPY (7.7 Å)
主引用文献Deep Classification of a Large Cryo-Em Dataset Defines the Conformational Landscape of the 26S Proteasome.
Proc.Natl.Acad.Sci.USA, 111, 2014
4E6F
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Crystal structure of a DUF4468 family protein (BACOVA_04320) from Bacteroides ovatus ATCC 8483 at 1.49 A resolution
分子名称: 1,2-ETHANEDIOL, NITRATE ION, Uncharacterized protein
著者Joint Center for Structural Genomics (JCSG)
登録日2012-03-15
公開日2012-07-04
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Crystal structure of a hypothetical protein (BACOVA_04320) from Bacteroides ovatus ATCC 8483 at 1.49 A resolution
To be published
4GWQ
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Structure of the Mediator Head Module from S. cerevisiae in complex with the carboxy-terminal domain (CTD) of RNA Polymerase II Rpb1 subunit
分子名称: DNA-directed RNA polymerase II subunit RPB1, Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, ...
著者Robinson, P.J.J, Bushnell, D.A, Trnka, M.J, Burlingame, A.L, Kornberg, R.D.
登録日2012-09-03
公開日2012-10-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GWP
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Structure of the Mediator Head Module from S. cerevisiae
分子名称: Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, Mediator of RNA polymerase II transcription subunit 18, ...
著者Robinson, P.J.J, Bushnell, D.A, Trnka, M.J, Burlingame, A.L, Kornberg, R.D.
登録日2012-09-03
公開日2012-10-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GFX
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BU of 4gfx by Molmil
Crystal structure of the N-terminal domain of TXNIP
分子名称: GLYCEROL, Thioredoxin-interacting protein
著者Hwang, J, Kim, M.H.
登録日2012-08-04
公開日2014-02-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein.
Nat Commun, 5, 2014
6DF4
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TAF1-BD2 in complex with Cpd8 (6-(but-3-en-1-yl)-4-(3-(morpholine-4-carbonyl)phenyl)-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one)
分子名称: 6-(but-3-en-1-yl)-4-[3-(morpholine-4-carbonyl)phenyl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one, Transcription initiation factor TFIID subunit
著者Murray, J.M, Tang, Y.
登録日2018-05-14
公開日2018-10-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like.
J. Med. Chem., 61, 2018
6DF7
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TAF1-BD2 in complex with Cpd27 (6-(but-3-en-1-yl)-4-(1-methyl-6-(morpholine-4-carbonyl)-1H-benzo[d]imidazol-4-yl)-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one)
分子名称: 6-(but-3-en-1-yl)-4-[1-methyl-6-(morpholine-4-carbonyl)-1H-benzimidazol-4-yl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one, Transcription initiation factor TFIID subunit
著者Murray, J.M.
登録日2018-05-14
公開日2018-11-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like.
J. Med. Chem., 61, 2018
6TPS
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early intermediate RNA Polymerase I Pre-initiation complex - eiPIC
分子名称: DNA foreign, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, ...
著者Pilsl, M, Engel, C.
登録日2019-12-14
公開日2020-03-18
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Structural basis of RNA polymerase I pre-initiation complex formation and promoter melting.
Nat Commun, 11, 2020
1U6G
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BU of 1u6g by Molmil
Crystal Structure of The Cand1-Cul1-Roc1 Complex
分子名称: Cullin homolog 1, RING-box protein 1, TIP120 protein, ...
著者Goldenberg, S.J, Shumway, S.D, Cascio, T.C, Garbutt, K.C, Liu, J, Xiong, Y, Zheng, N.
登録日2004-07-29
公開日2004-12-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases
Cell(Cambridge,Mass.), 119, 2004
6RUO
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BU of 6ruo by Molmil
RNA Polymerase I Open Complex conformation 1
分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
著者Mueller, C.W, Sadian, Y, Tafur, L.
登録日2019-05-28
公開日2019-12-11
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun, 10, 2019
6RRD
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BU of 6rrd by Molmil
RNA Polymerase I Pre-initiation complex DNA opening intermediate 1
分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
著者Mueller, C.W, Sadian, Y, Tafur, L.
登録日2019-05-17
公開日2019-12-11
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun, 10, 2019
6RUI
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RNA Polymerase I Pre-initiation complex DNA opening intermediate 2
分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
著者Mueller, C.W, Sadian, Y, Tafur, L.
登録日2019-05-28
公開日2019-12-11
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun, 10, 2019
6RQL
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RNA Polymerase I Closed Conformation 2 (CC2)
分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
著者Mueller, C.W, Sadian, Y, Tafur, L.
登録日2019-05-16
公開日2019-12-11
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun, 10, 2019
6RWE
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BU of 6rwe by Molmil
RNA Polymerase I Open Complex conformation 2
分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
著者Mueller, C.W, Sadian, Y, Tafur, L.
登録日2019-06-04
公開日2019-12-11
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun, 10, 2019
6RQH
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BU of 6rqh by Molmil
RNA Polymerase I Closed Conformation 1 (CC1)
分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
著者Mueller, C.W, Sadian, Y, Tafur, L.
登録日2019-05-15
公開日2019-12-11
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun, 10, 2019
8JG4
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BU of 8jg4 by Molmil
Crystal Structure of YAF9A YEATS bound to H3K27cr peptide
分子名称: Histone H3.1, Transcription initiation factor TFIID subunit 14b
著者Li, H.T, Liu, W.Q.
登録日2023-05-19
公開日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of YAF9A YEATS bound to H3K27cr peptide
To Be Published
7KTR
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BU of 7ktr by Molmil
Cryo-EM structure of the human SAGA coactivator complex (TRRAP, core)
分子名称: Ataxin-7, INOSITOL HEXAKISPHOSPHATE, Isoform 3 of Transcription factor SPT20 homolog, ...
著者Herbst, D.A, Esbin, M.N, Nogales, E.
登録日2020-11-24
公開日2021-11-10
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Structure of the human SAGA coactivator complex.
Nat.Struct.Mol.Biol., 28, 2021
7KTS
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Negative stain EM structure of the human SAGA coactivator complex (TRRAP, core, splicing module)
分子名称: Ataxin-7, Isoform 3 of Transcription factor SPT20 homolog, STAGA complex 65 subunit gamma, ...
著者Herbst, D.A, Esbin, M.N, Nogales, E.
登録日2020-11-24
公開日2021-11-10
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (19.09 Å)
主引用文献Structure of the human SAGA coactivator complex.
Nat.Struct.Mol.Biol., 28, 2021
7KW7
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Atomic cryoEM structure of Hsp90-Hsp70-Hop-GR
分子名称: ADENOSINE-5'-DIPHOSPHATE, Glucocorticoid receptor, Heat shock 70 kDa protein 1A, ...
著者Wang, R.Y, Noddings, C.M, Kirschke, E, Myasnikov, A, Johnson, J.L, Agard, D.A.
登録日2020-11-30
公開日2021-12-08
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Structure of Hsp90-Hsp70-Hop-GR reveals the Hsp90 client-loading mechanism.
Nature, 601, 2022
1BH8
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HTAFII18/HTAFII28 HETERODIMER CRYSTAL STRUCTURE
分子名称: TAFII18, TAFII28
著者Birck, C, Poch, O, Romier, C, Ruff, M, Mengus, G, Lavigne, A.-C, Davidson, I, Moras, D.
登録日1998-06-16
公開日1999-06-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family.
Cell(Cambridge,Mass.), 94, 1998
1BH9
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HTAFII18/HTAFII28 HETERODIMER CRYSTAL STRUCTURE WITH BOUND PCMBS
分子名称: PARA-MERCURY-BENZENESULFONIC ACID, TAFII18, TAFII28
著者Birck, C, Poch, O, Romier, C, Ruff, M, Mengus, G, Lavigne, A.-C, Davidson, I, Moras, D.
登録日1998-06-16
公開日1999-06-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family.
Cell(Cambridge,Mass.), 94, 1998
2K16
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BU of 2k16 by Molmil
Solution structure of the free TAF3 PHD domain
分子名称: Transcription initiation factor TFIID subunit 3, ZINC ION
著者van Ingen, H, van Schaik, F.M.A, Wienk, H, Timmers, M, Boelens, R.
登録日2008-02-22
公開日2008-07-15
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Recognition of the H3K4me3 mark by the TAF3-PHD finger
To be Published

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件を2024-10-16に公開中

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