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1L9U
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THERMUS AQUATICUS RNA POLYMERASE HOLOENZYME AT 4 A RESOLUTION
分子名称: MAGNESIUM ION, RNA POLYMERASE, ALPHA SUBUNIT, ...
著者Murakami, K.S, Masuda, S, Darst, S.A.
登録日2002-03-26
公開日2002-05-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structural basis of transcription initiation: RNA polymerase holoenzyme at 4 A resolution.
Science, 296, 2002
1L9Z
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Thermus aquaticus RNA Polymerase Holoenzyme/Fork-Junction Promoter DNA Complex at 6.5 A Resolution
分子名称: MAGNESIUM ION, RNA POLYMERASE, ALPHA SUBUNIT, ...
著者Murakami, K.S, Masuda, S, Campbell, E.A, Muzzin, O, Darst, S.A.
登録日2002-03-27
公開日2002-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (6.5 Å)
主引用文献Structural basis of transcription initiation: an RNA polymerase holoenzyme-DNA complex.
Science, 296, 2002
3SFG
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crystal structure of murine norovirus RNA dependent RNA polymerase in complex with 2thiouridine(2TU)
分子名称: 1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one, GLYCEROL, MAGNESIUM ION, ...
著者Kim, K.H, Alam, I.
登録日2011-06-13
公開日2012-05-09
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.209 Å)
主引用文献Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase in complex with 2-thiouridine or ribavirin.
Virology, 426, 2012
1YVX
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Hepatitis C Virus RNA Polymerase Genotype 2a In Complex With Non- Nucleoside Analogue Inhibitor
分子名称: 3-[ISOPROPYL(4-METHYLBENZOYL)AMINO]-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID, RNA dependent RNA polymerase, SULFATE ION
著者Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G.
登録日2005-02-16
公開日2005-03-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors.
J.Biol.Chem., 280, 2005
2PPB
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Crystal structure of the T. thermophilus RNAP polymerase elongation complex with the ntp substrate analog and antibiotic streptolydigin
分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA (5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3'), ...
著者Vassylyev, D.G, Vassylyeva, M.N, Artsimovitch, I, Landick, R.
登録日2007-04-28
公開日2007-07-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for substrate loading in bacterial RNA polymerase.
Nature, 448, 2007
1YVZ
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Hepatitis C Virus RNA Polymerase Genotype 2a In Complex With Non- Nucleoside Analogue Inhibitor
分子名称: 3-[(2,4-DICHLOROBENZOYL)(ISOPROPYL)AMINO]-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID, RNA dependent RNA polymerase, SULFATE ION
著者Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G.
登録日2005-02-16
公開日2005-03-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors.
J.Biol.Chem., 280, 2005
2GHO
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Recombinant Thermus aquaticus RNA polymerase for Structural Studies
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta',DNA-directed RNA polymerase subunit beta'
著者Lamour, V, Darst, S.A.
登録日2006-03-27
公開日2006-05-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (5 Å)
主引用文献Recombinant Thermus aquaticus RNA Polymerase for Structural Studies.
J.Mol.Biol., 359, 2006
1YNN
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Taq RNA polymerase-rifampicin complex
分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
著者Campbell, E.A, Pavlova, O, Zenkin, N, Leon, F, Irschik, H, Jansen, R, Severinov, K, Darst, S.A.
登録日2005-01-24
公開日2005-03-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase
Embo J., 24, 2005
7VB4
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A crystal structure of alphavirus nonstructural protein 4 (nsP4) reveals an intrinsically dynamic RNA-dependent RNA polymerase
分子名称: GLYCEROL, MAGNESIUM ION, RNA-directed RNA polymerase nsP4
著者Tan, Y.B, Luo, D.
登録日2021-08-30
公開日2022-02-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold.
Nucleic Acids Res., 50, 2022
7VW5
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Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold
分子名称: MAGNESIUM ION, RNA-directed RNA polymerase nsP4
著者Tan, Y.B, Luo, D.
登録日2021-11-09
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold.
Nucleic Acids Res., 50, 2022
2PI5
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T7 RNA polymerase complexed with a phi10 promoter
分子名称: 5'-D(*CP*TP*TP*C*CP*TP*AP*TP*AP*GP*TP*GP*AP*GP*TP*CP*GP*TP*AP*TP*TP*A)-3', 5'-D(*TP*AP*AP*TP*AP*CP*GP*AP*CP*TP*CP*AP*CP*T)-3', DNA-directed RNA polymerase
著者Kennedy, W.P, Momand, J.R, Yin, Y.W.
登録日2007-04-12
公開日2007-06-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mechanism for de novo RNA synthesis and initiating nucleotide specificity by t7 RNA polymerase.
J.Mol.Biol., 370, 2007
1I6V
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THERMUS AQUATICUS CORE RNA POLYMERASE-RIFAMPICIN COMPLEX
分子名称: DNA-DIRECTED RNA POLYMERASE, MAGNESIUM ION, RIFAMPICIN, ...
著者Campbell, E.A, Korzheva, N, Mustaev, A, Murakami, K, Goldfarb, A, Darst, S.A.
登録日2001-03-05
公開日2001-04-18
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural mechanism for rifampicin inhibition of bacterial rna polymerase.
Cell(Cambridge,Mass.), 104, 2001
1QKL
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hRPABC14.4, essential subunit of human RNA polymerases I, II and III
分子名称: DNA-DIRECTED RNA POLYMERASE II 14.4 KD POLYPEPTIDE
著者Del Rio-Portilla, F, Gaskell, A.G, Gilbert, D, Ladias, J.A.A, Wagner, G.
登録日1999-07-26
公開日1999-11-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure of the Hrpabc14.4 Subunit of Human RNA Polymerases
Nat.Struct.Biol., 6, 1999
7ASV
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Crystal structure of tWHD2 of Rpc5 subunit of human RNA Polymerase III
分子名称: ACETATE ION, DNA-directed RNA polymerase III subunit RPC5
著者Vannini, A, Abascal-Palacios, G, Ramsay, E.P.
登録日2020-10-28
公開日2020-12-30
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure of human RNA polymerase III.
Nat Commun, 11, 2020
7ASU
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Crystal structure of tWHD1 of Rpc5 subunit of human RNA Polymerase III
分子名称: DNA-directed RNA polymerase III subunit RPC5, ZINC ION
著者Vannini, A, Abascal-Palacios, G, Ramsay, E.P.
登録日2020-10-28
公開日2020-12-30
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Structure of human RNA polymerase III.
Nat Commun, 11, 2020
4B02
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The C-terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage phi6 RNA-Dependent RNA Polymerase
分子名称: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
著者Sarin, L.P, Wright, S, Chen, Q, Degerth, L.H, Stuart, D.I, Grimes, J.M, Bamford, D.H, Poranen, M.M.
登録日2012-06-27
公開日2012-08-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The C-Terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage Phi6 RNA-Dependent RNA Polymerase.
Virology, 432, 2012
2PUS
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Unprecedented activation mechanism of a non-canonical RNA-dependent RNA polymerase
分子名称: IBDV VP1 RNA-dependant RNA polymerase
著者Garriga, D, Navarro, A, Querol-Audi, J, Abaitua, F, Rodriguez, J.F, Verdaguer, N.
登録日2007-05-09
公開日2007-11-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Activation mechanism of a noncanonical RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.Usa, 104, 2007
1HQM
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CRYSTAL STRUCTURE OF THERMUS AQUATICUS CORE RNA POLYMERASE-INCLUDES COMPLETE STRUCTURE WITH SIDE-CHAINS (EXCEPT FOR DISORDERED REGIONS)-FURTHER REFINED FROM ORIGINAL DEPOSITION-CONTAINS ADDITIONAL SEQUENCE INFORMATION
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Minakhin, L, Bhagat, S, Brunning, A, Campbell, E.A, Darst, S.A, Ebright, R.H, Severinov, K.
登録日2000-12-18
公開日2001-02-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly.
Proc.Natl.Acad.Sci.USA, 98, 2001
1MSW
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Structural basis for the transition from initiation to elongation transcription in T7 RNA polymerase
分子名称: DNA-directed RNA polymerase, Non-Template DNA, RNA message, ...
著者Yin, Y.W, Steitz, T.A.
登録日2002-09-19
公開日2002-11-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for the Transition from Initiation to Elongation Transcription in T7 RNA Polymerase
Science, 298, 2002
1H38
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Structure of a T7 RNA polymerase elongation complex at 2.9A resolution
分子名称: 5'-D(*GP*GP*GP*AP*AP*TP*CP*GP*AP*CP *AP*TP*CP*GP*CP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*AP*TP*TP*CP*CP*CP)-3', 5'-R(*AP*AP*CP*UP*GP*CP*GP*GP*CP*GP *AP*U)-3', ...
著者Tahirov, T.H, Temyakov, D, Anikin, M, Patlan, V, McAllister, W.T, Vassylyev, D.G, Yokoyama, S.
登録日2002-08-24
公開日2002-11-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of a T7 RNA Polymerase Elongation Complex at 2.9 A Resolution
Nature, 420, 2002
5I62
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Crystal structure of the insertion loop deletion mutant of the RNA-dependent RNA polymerase of a human picorbirnavirus
分子名称: Potential RNA-dependent RNA polymerase
著者Collier, A.M, Guo, Y.R, Tao, Y.J.
登録日2016-02-15
公開日2016-03-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus.
Plos Pathog., 12, 2016
5HFZ
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Mmi1 YTH domain
分子名称: YTH domain-containing protein mmi1
著者Chatterjee, D, Goldgur, Y, Shuman, S.
登録日2016-01-07
公開日2016-02-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Transcription of lncRNA prt, clustered prt RNA sites for Mmi1 binding, and RNA polymerase II CTD phospho-sites govern the repression of pho1 gene expression under phosphate-replete conditions in fission yeast.
Rna, 22, 2016
5I61
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Crystal structure of the RNA-dependent RNA polymerase of a human picorbirnavirus
分子名称: Potential RNA-dependent RNA polymerase
著者Collier, A.M, Guo, Y.R, Tao, Y.J.
登録日2016-02-15
公開日2016-03-16
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus.
Plos Pathog., 12, 2016
2PA8
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X-Ray Crystal Structure of the D/L Subcomplex of the Sulfolobus Solfataricus RNA polymerase
分子名称: DNA-directed RNA polymerase subunit D, DNA-directed RNA polymerase subunit L, FE3-S4 CLUSTER, ...
著者Hirata, A, Murakami, K.S.
登録日2007-03-27
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献The X-ray crystal structure of RNA polymerase from Archaea.
Nature, 451, 2008
7BTF
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SARS-CoV-2 RNA-dependent RNA polymerase in complex with cofactors in reduced condition
分子名称: Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase, ...
著者Gao, Y, Yan, L, Huang, Y, Liu, F, Cao, L, Wang, T, Wang, Q, Lou, Z, Rao, Z.
登録日2020-04-01
公開日2020-04-08
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Structure of the RNA-dependent RNA polymerase from COVID-19 virus.
Science, 368, 2020

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