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2MI1
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BU of 2mi1 by Molmil
Somatostatin-14 solution structure in 5% D-mannitol
分子名称: Somatostatin-14
著者Anoop, A, Ranganathan, S, Pratihar, S.
登録日2013-12-08
公開日2014-05-07
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Elucidating the role of disulfide bond on amyloid formation and fibril reversibility of somatostatin-14: relevance to its storage and secretion.
J.Biol.Chem., 289, 2014
7XBQ
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BU of 7xbq by Molmil
Crystal structure of potato 14-3-3 protein St14f
分子名称: Putative 14-3-3 protein
著者Harada, K, Kojima, C, Yamashita, E, Nakagawa, A.
登録日2022-03-21
公開日2022-07-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structure of potato 14-3-3 protein St14f revealed the importance of helix I in StFDL1 recognition.
Sci Rep, 12, 2022
8AQ1
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BU of 8aq1 by Molmil
small molecule stabilizer for ERalpha and 14-3-3 (1083743)
分子名称: (2S,6R)-N-[[7-(2-chloranylethanoyl)-7-azaspiro[3.5]nonan-2-yl]methyl]-4-[(4-chlorophenyl)amino]-2,6-dimethyl-oxane-4-carboxamide, 14-3-3 protein sigma, Estrogen receptor, ...
著者Visser, E.J, Vandenboorn, E.M.F, Ottmann, C.
登録日2022-08-11
公開日2023-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure-Based Optimization of Covalent, Small-Molecule Stabilizers of the 14-3-3 sigma /ER alpha Protein-Protein Interaction from Nonselective Fragments.
J.Am.Chem.Soc., 145, 2023
2IN2
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BU of 2in2 by Molmil
NMR Structure of the Apo Human Rhinovirus 3C Protease (serotype 14)
分子名称: Picornain 3C
著者Bjorndahl, T.C, Semenchenko, V, Wishart, D.S.
登録日2006-10-05
公開日2006-10-24
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献NMR solution structures of the apo and peptide-inhibited human rhinovirus 3C protease (Serotype 14): structural and dynamic comparison.
Biochemistry, 46, 2007
6YIC
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BU of 6yic by Molmil
14-3-3 sigma in complex with SMAD4 pS403 peptide
分子名称: 14-3-3 protein sigma, CALCIUM ION, GLYCEROL, ...
著者Kiehstaller, S, Graf, S, Hennig, S.
登録日2020-04-01
公開日2021-04-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Identification and characterization of 14-3-3/SMAD protein-protein-interactions
To Be Published
6YIA
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BU of 6yia by Molmil
14-3-3 sigma in complex with SMAD2 pS465 peptide
分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ...
著者Kiehstaller, S, Graf, S, Hennig, S.
登録日2020-04-01
公開日2021-04-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Identification and characterization of 14-3-3/SMAD protein-protein-interactions
To Be Published
6YIB
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BU of 6yib by Molmil
14-3-3 sigma in complex with SMAD3 pS423 peptide
分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ...
著者Kiehstaller, S, Graf, S, Hennig, S.
登録日2020-04-01
公開日2021-04-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Identification and characterization of 14-3-3/SMAD protein-protein-interactions
To Be Published
7DVN
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BU of 7dvn by Molmil
Crystal structure of a MarR family protein in complex with a lipid-like effector molecule from the psychrophilic bacterium Paenisporosarcina sp. TG-14
分子名称: MarR family transcriptional regulator, PALMITIC ACID
著者Lee, C.W, Hwang, J, Do, H, Lee, J.H.
登録日2021-01-14
公開日2021-11-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of a MarR family protein from the psychrophilic bacterium Paenisporosarcina sp. TG-14 in complex with a lipid-like molecule.
Iucrj, 8, 2021
6MRW
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BU of 6mrw by Molmil
14-meric ClyA pore complex
分子名称: Hemolysin E, chromosomal
著者Peng, W, de Souza Santos, M, Li, Y, Tomchick, D.R, Orth, K.
登録日2018-10-15
公開日2019-05-15
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers.
Plos One, 14, 2019
6T80
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BU of 6t80 by Molmil
Human 14-3-3 sigma fused to the AANAT peptide including phosphoserine-205
分子名称: 14-3-3 protein sigma, AANAT peptide
著者Sluchanko, N.N, Tugaeva, K.V, Titterington, J, Antson, A.A.
登録日2019-10-23
公開日2020-11-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Human 14-3-3 sigma fused to the AANAT peptide including phosphoserine-205
To Be Published
6NYB
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BU of 6nyb by Molmil
Structure of a MAPK pathway complex
分子名称: 14-3-3 protein zeta, 5-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide, ADENOSINE-5'-DIPHOSPHATE, ...
著者Park, E, Rawson, S, Li, K, Jeon, H, Eck, M.J.
登録日2019-02-11
公開日2019-10-09
最終更新日2020-04-22
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes.
Nature, 575, 2019
2J57
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BU of 2j57 by Molmil
X-ray reduced Paraccocus denitrificans methylamine dehydrogenase N- quinol in complex with amicyanin.
分子名称: AMICYANIN, COPPER (II) ION, METHYLAMINE DEHYDROGENASE HEAVY CHAIN, ...
著者Pearson, A.R, Pahl, R, Davidson, V.L, Wilmot, C.M.
登録日2006-09-12
公開日2007-01-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Tracking X-Ray-Derived Redox Changes in Crystals of a Methylamine Dehydrogenase/Amicyanin Complex Using Single-Crystal Uv/Vis Microspectrophotometry.
J.Synchrotron Radiat., 14, 2007
2J56
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BU of 2j56 by Molmil
X-ray reduced Paraccocus denitrificans methylamine dehydrogenase N- semiquinone in complex with amicyanin.
分子名称: AMICYANIN, COPPER (II) ION, GLYCEROL, ...
著者Pearson, A.R, Pahl, R, Davidson, V.L, Wilmot, C.M.
登録日2006-09-12
公開日2007-01-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Tracking X-Ray-Derived Redox Changes in Crystals of a Methylamine Dehydrogenase/Amicyanin Complex Using Single-Crystal Uv/Vis Microspectrophotometry.
J.Synchrotron Radiat., 14, 2007
2J55
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BU of 2j55 by Molmil
X-ray reduced Paraccocus denitrificans methylamine dehydrogenase O- quinone in complex with amicyanin.
分子名称: AMICYANIN, COPPER (II) ION, GLYCEROL, ...
著者Pearson, A.R, Pahl, R, Davidson, V.L, Wilmot, C.M.
登録日2006-09-12
公開日2007-01-23
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Tracking X-Ray-Derived Redox Changes in Crystals of a Methylamine Dehydrogenase/Amicyanin Complex Using Single-Crystal Uv/Vis Microspectrophotometry.
J.Synchrotron Radiat., 14, 2007
9AXC
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BU of 9axc by Molmil
Activated CRAF/MEK heterotetramer from focused refinement of CRAF/MEK/14-3-3 complex
分子名称: Dual specificity mitogen-activated protein kinase kinase 1, GST26/CRAF chimera, N-[3-fluoro-4-({7-[(3-fluoropyridin-2-yl)oxy]-4-methyl-2-oxo-2H-1-benzopyran-3-yl}methyl)pyridin-2-yl]-N'-methylsulfuric diamide
著者Quade, B, Cohen, S.E, Huang, X.
登録日2024-03-06
公開日2024-04-17
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (4.16 Å)
主引用文献The Pan-RAF-MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS-MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers.
Cancer Discov, 14, 2024
5WFX
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BU of 5wfx by Molmil
Structural basis for the interaction of 14-3-3beta with Tricarboxylic Acid Cycle intermediate Malate
分子名称: 14-3-3 protein beta/alpha
著者Hou, Z.Q.
登録日2017-07-12
公開日2018-05-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.651 Å)
主引用文献Structural basis for the interaction of 14-3-3 beta withTricarboxylic Acid Cycle intermediate Malate
To Be Published
5WFU
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BU of 5wfu by Molmil
Structural basis for the interaction of 14-3-3beta with Tricarboxylic Acid Cycle intermediate Malate
分子名称: 14-3-3 protein beta/alpha, D-MALATE
著者Hou, Z.Q, Liu, X.Y.
登録日2017-07-12
公開日2018-07-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural basis for the interaction of 14-3-3beta with Tricarboxylic Acid Cycle intermediate Malate
To Be Published
5LVZ
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BU of 5lvz by Molmil
Crystal structure of yeast 14-3-3 protein from Lachancea thermotolerans
分子名称: KLTH0G14146p
著者Klima, M, Boura, E.
登録日2016-09-14
公開日2016-10-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structures of a yeast 14-3-3 protein from Lachancea thermotolerans in the unliganded form and bound to a human lipid kinase PI4KB-derived peptide reveal high evolutionary conservation.
Acta Crystallogr.,Sect.F, 72, 2016
4WV1
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BU of 4wv1 by Molmil
Crystal structure of the FGFR2 D2 domain in complex with Fab 2B.1.3
分子名称: Fab heavy chain, Fab light chain, Fibroblast growth factor receptor 2
著者Yin, Y, Carter, P.J.
登録日2014-11-04
公開日2015-09-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.362 Å)
主引用文献Redesigning a Monospecific Anti-FGFR3 Antibody to Add Selectivity for FGFR2 and Expand Antitumor Activity.
Mol.Cancer Ther., 14, 2015
5XY9
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BU of 5xy9 by Molmil
Structure of the MST4 and 14-3-3 complex
分子名称: 14-3-3 protein zeta/delta, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, GLYCEROL, ...
著者Shi, Z.B, Zhou, Z.C.
登録日2017-07-06
公開日2018-07-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Structure of the MST4 and 14-3-3 complex
To Be Published
4QLI
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BU of 4qli by Molmil
A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation
分子名称: 14-3-3 protein sigma, GLYCEROL, MAGNESIUM ION, ...
著者Bier, D, Ottmann, C.
登録日2014-06-12
公開日2015-06-17
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation
To be Published
7OPW
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BU of 7opw by Molmil
Ternary complex of 14-3-3 sigma, Estrogen Receptor alfa phosphopeptide, and WQ136
分子名称: 14-3-3 protein sigma, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
著者Centorrino, F, Ottmann, C.
登録日2021-06-01
公開日2022-06-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献A crystallography-based study of fragment extensions into the 14-3-3 binding groove
To Be Published
7OQG
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BU of 7oqg by Molmil
Ternary complex of 14-3-3 sigma, Amot-p130 phosphopeptide, and WQ136
分子名称: 14-3-3 protein sigma, Amot-p130 phosphopeptide (pS175), BETA-MERCAPTOETHANOL, ...
著者Centorrino, F, Ottmann, C.
登録日2021-06-03
公開日2022-06-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A crystallography-based study of fragment extensions into the 14-3-3 binding groove
To Be Published
7OQJ
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BU of 7oqj by Molmil
Ternary complex of 14-3-3 sigma, Amot-p130 phosphopeptide, and WQ162
分子名称: 14-3-3 protein sigma, Amot-p130 phosphopeptide (pS175), CHLORIDE ION, ...
著者Centorrino, F, Ottmann, C.
登録日2021-06-03
公開日2022-06-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A crystallography-based study of fragment extensions into the 14-3-3 binding groove
To Be Published
7OQS
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BU of 7oqs by Molmil
Ternary complex of 14-3-3 sigma, Amot-p130 phosphopeptide, and WQ177
分子名称: 14-3-3 protein sigma, 2-(1,3-benzodioxol-5-yl)-~{N}-[(5-carbamimidoyl-3-phenyl-thiophen-2-yl)methyl]ethanamide, Amot-p130 phosphopeptide (pS175), ...
著者Centorrino, F, Ottmann, C.
登録日2021-06-04
公開日2022-06-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献A crystallography-based study of fragment extensions into the 14-3-3 binding groove
To Be Published

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