1YNN
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![BU of 1ynn by Molmil](/molmil-images/mine/1ynn) | Taq RNA polymerase-rifampicin complex | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | 著者 | Campbell, E.A, Pavlova, O, Zenkin, N, Leon, F, Irschik, H, Jansen, R, Severinov, K, Darst, S.A. | 登録日 | 2005-01-24 | 公開日 | 2005-03-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase Embo J., 24, 2005
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6PO2
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![BU of 6po2 by Molmil](/molmil-images/mine/6po2) | In situ structure of BTV RNA-dependent RNA polymerase in BTV core | 分子名称: | Inner core structural protein VP3, RNA-directed RNA polymerase | 著者 | He, Y, Shivakoti, S, Ding, K, Cui, Y, Roy, P, Zhou, Z.H. | 登録日 | 2019-07-03 | 公開日 | 2019-08-07 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | In situ structures of RNA-dependent RNA polymerase inside bluetongue virus before and after uncoating. Proc.Natl.Acad.Sci.USA, 116, 2019
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6PNS
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![BU of 6pns by Molmil](/molmil-images/mine/6pns) | In situ structure of BTV RNA-dependent RNA polymerase in BTV virion | 分子名称: | Inner core structural protein VP3, RNA-directed RNA polymerase | 著者 | He, Y, Shivakoti, S, Ding, K, Cui, Y, Roy, P, Zhou, Z.H. | 登録日 | 2019-07-03 | 公開日 | 2019-08-07 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | In situ structures of RNA-dependent RNA polymerase inside bluetongue virus before and after uncoating. Proc.Natl.Acad.Sci.USA, 116, 2019
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3HKZ
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6ZFB
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![BU of 6zfb by Molmil](/molmil-images/mine/6zfb) | Structure of the B. subtilis RNA POLYMERASE in complex with HelD (dimer) | 分子名称: | DNA helicase, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Pei, H.-P, Hilal, T, Huang, Y.-H, Said, N, Loll, B, Wahl, M.C. | 登録日 | 2020-06-17 | 公開日 | 2020-10-14 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | The delta subunit and NTPase HelD institute a two-pronged mechanism for RNA polymerase recycling. Nat Commun, 11, 2020
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4QJV
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4MQ9
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![BU of 4mq9 by Molmil](/molmil-images/mine/4mq9) | Crystal structure of Thermus thermophilus RNA polymerase holoenzyme in complex with GE23077 | 分子名称: | (2Z)-2-methylbut-2-enoic acid, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Ho, M.X, Arnold, E, Ebright, R.H, Zhang, Y, Tuske, S. | 登録日 | 2013-09-16 | 公開日 | 2014-05-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides. Elife, 3, 2014
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4OIR
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![BU of 4oir by Molmil](/molmil-images/mine/4oir) | Crystal structure of Thermus thermophilus RNA polymerase transcription initiation complex soaked with GE23077 and rifamycin SV | 分子名称: | (2Z)-2-methylbut-2-enoic acid, 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', ... | 著者 | Zhang, Y, Ebright, R.H, Arnold, E. | 登録日 | 2014-01-20 | 公開日 | 2014-05-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.105 Å) | 主引用文献 | GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides. Elife, 3, 2014
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2CW0
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![BU of 2cw0 by Molmil](/molmil-images/mine/2cw0) | Crystal structure of Thermus thermophilus RNA polymerase holoenzyme at 3.3 angstroms resolution | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | 著者 | Tuske, S, Sarafianos, S.G, Wang, X, Hudson, B, Sineva, E, Mukhopadhyay, J, Birktoft, J.J, Leroy, O, Ismail, S, Clark Jr, A.D, Dharia, C, Napoli, A, Laptenko, O, Lee, J, Borukhov, S, Ebright, R.H, Arnold, E. | 登録日 | 2005-06-15 | 公開日 | 2005-09-20 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation Cell(Cambridge,Mass.), 122, 2005
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2A6E
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![BU of 2a6e by Molmil](/molmil-images/mine/2a6e) | Crystal structure of the T. Thermophilus RNA polymerase holoenzyme | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | 著者 | Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-07-02 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
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2A68
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![BU of 2a68 by Molmil](/molmil-images/mine/2a68) | Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic rifabutin | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | 著者 | Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-07-01 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
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2A69
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![BU of 2a69 by Molmil](/molmil-images/mine/2a69) | Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic rifapentin | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | 著者 | Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-07-02 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
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2C35
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![BU of 2c35 by Molmil](/molmil-images/mine/2c35) | Subunits Rpb4 and Rpb7 of human RNA polymerase II | 分子名称: | DNA-DIRECTED RNA POLYMERASE II 16 KDA POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 19 KDA POLYPEPTIDE | 著者 | Meka, H, Werner, F, Cordell, S.C, Onesti, S, Brick, P. | 登録日 | 2005-10-04 | 公開日 | 2005-11-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structure and RNA Binding of the Rpb4/Rpb7 Subunits of Human RNA Polymerase II. Nucleic Acids Res., 33, 2005
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7MKE
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![BU of 7mke by Molmil](/molmil-images/mine/7mke) | Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 2) | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Saecker, R.M, Darst, S.A, Chen, J. | 登録日 | 2021-04-23 | 公開日 | 2021-09-29 | 最終更新日 | 2021-10-13 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
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7MKJ
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![BU of 7mkj by Molmil](/molmil-images/mine/7mkj) | Cryo-EM structure of Escherichia coli RNA polymerase bound to T7A1 promoter DNA | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Saecker, R.M, Darst, S.A, Chen, J. | 登録日 | 2021-04-23 | 公開日 | 2021-09-29 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
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7MKI
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![BU of 7mki by Molmil](/molmil-images/mine/7mki) | Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR (-5G to C) promoter DNA | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Saecker, R.M, Darst, S.A, Chen, J. | 登録日 | 2021-04-23 | 公開日 | 2021-09-29 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
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7MKD
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![BU of 7mkd by Molmil](/molmil-images/mine/7mkd) | Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 1) | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Saecker, R.M, Darst, S.A, Chen, J. | 登録日 | 2021-04-23 | 公開日 | 2021-09-29 | 最終更新日 | 2021-10-13 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
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5VT0
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1L9U
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![BU of 1l9u by Molmil](/molmil-images/mine/1l9u) | THERMUS AQUATICUS RNA POLYMERASE HOLOENZYME AT 4 A RESOLUTION | 分子名称: | MAGNESIUM ION, RNA POLYMERASE, ALPHA SUBUNIT, ... | 著者 | Murakami, K.S, Masuda, S, Darst, S.A. | 登録日 | 2002-03-26 | 公開日 | 2002-05-22 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Structural basis of transcription initiation: RNA polymerase holoenzyme at 4 A resolution. Science, 296, 2002
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1YV2
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![BU of 1yv2 by Molmil](/molmil-images/mine/1yv2) | Hepatitis C virus NS5B RNA-dependent RNA Polymerase genotype 2a | 分子名称: | GLYCEROL, RNA dependent RNA polymerase, SULFATE ION | 著者 | Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. | 登録日 | 2005-02-14 | 公開日 | 2005-03-22 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structures of the RNA-dependent RNA Polymerase Genotype 2a of Hepatitis C Virus Reveal Two Conformations and Suggest Mechanisms of Inhibition by Non-nucleoside Inhibitors J.Biol.Chem., 280, 2005
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2PMZ
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![BU of 2pmz by Molmil](/molmil-images/mine/2pmz) | Archaeal RNA polymerase from Sulfolobus solfataricus | 分子名称: | DNA-directed RNA polymerase subunit A, DNA-directed RNA polymerase subunit A", DNA-directed RNA polymerase subunit B, ... | 著者 | Murakami, K.S. | 登録日 | 2007-04-23 | 公開日 | 2008-02-12 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | The X-ray crystal structure of RNA polymerase from Archaea Nature, 451, 2008
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7ASU
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7ASV
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1L9Z
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![BU of 1l9z by Molmil](/molmil-images/mine/1l9z) | Thermus aquaticus RNA Polymerase Holoenzyme/Fork-Junction Promoter DNA Complex at 6.5 A Resolution | 分子名称: | MAGNESIUM ION, RNA POLYMERASE, ALPHA SUBUNIT, ... | 著者 | Murakami, K.S, Masuda, S, Campbell, E.A, Muzzin, O, Darst, S.A. | 登録日 | 2002-03-27 | 公開日 | 2002-05-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (6.5 Å) | 主引用文献 | Structural basis of transcription initiation: an RNA polymerase holoenzyme-DNA complex. Science, 296, 2002
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1KHV
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![BU of 1khv by Molmil](/molmil-images/mine/1khv) | Crystal Structure of Rabbit Hemorrhagic Disease Virus RNA-dependent RNA polymerase complexed with Lu3+ | 分子名称: | LUTETIUM (III) ION, RNA-DIRECTED RNA POLYMERASE | 著者 | Ng, K.K, Cherney, M.M, Vazquez, A.L, Machin, A, Alonso, J.M, Parra, F, James, M.N. | 登録日 | 2001-12-01 | 公開日 | 2002-01-16 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase. J.Biol.Chem., 277, 2002
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