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7TBW
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The structure of ATP-bound ABCA1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Sun, Y, Li, X.
登録日2021-12-22
公開日2022-01-26
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
7TC0
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The structure of human ABCA1 in digitonin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette, ...
著者Sun, Y, Li, X.
登録日2021-12-22
公開日2022-01-26
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
7TBY
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The structure of human ABCA1 in nanodisc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette, ...
著者Sun, Y, Li, X.
登録日2021-12-22
公開日2022-01-26
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
7TBZ
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BU of 7tbz by Molmil
The structure of ABCA1 Y482C
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette, ...
著者Sun, Y, Li, X.
登録日2021-12-22
公開日2022-01-26
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
7T54
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Cryo-EM structure of ATP-bound PCAT1 in the outward-facing conformation
分子名称: ABC-type bacteriocin transporter, ADENOSINE-5'-TRIPHOSPHATE
著者Kieuvongngam, V, Chen, J.
登録日2021-12-11
公開日2022-02-02
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T57
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Cryo-EM structure of PCAT1 in the inward-facing narrow conformation under ATP turnover condition
分子名称: ABC-type bacteriocin transporter, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Kieuvongngam, V, Chen, J.
登録日2021-12-11
公開日2022-02-02
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T55
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BU of 7t55 by Molmil
Cryo-EM structure of PCAT1 in the inward-facing wide conformation under ATP turnover condition
分子名称: ABC-type bacteriocin transporter, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Kieuvongngam, V, Chen, J.
登録日2021-12-11
公開日2022-02-02
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.
Proc.Natl.Acad.Sci.USA, 119, 2022
7MU0
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MtbEttA in the ADP bound state
分子名称: ADENOSINE-5'-DIPHOSPHATE, Energy-dependent translational throttle protein EttA, MAGNESIUM ION
著者Cui, Z, Zhang, J.
登録日2021-05-14
公開日2022-02-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis.
Nat Commun, 13, 2022
7MSM
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BU of 7msm by Molmil
Mtb 70SIC in complex with MtbEttA at Trans_R0 state
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Cui, Z, Zhang, J.
登録日2021-05-11
公開日2022-02-02
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis.
Nat Commun, 13, 2022
7MSZ
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Mtb 70SIC in complex with MtbEttA at Trans_R1 state
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Cui, Z, Zhang, J.
登録日2021-05-12
公開日2022-02-02
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis.
Nat Commun, 13, 2022
7MSH
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BU of 7msh by Molmil
Mtb 70SIC in complex with MtbEttA at Pre_R1 state
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Cui, Z, Zhang, J.
登録日2021-05-11
公開日2022-02-02
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis.
Nat Commun, 13, 2022
7MSC
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BU of 7msc by Molmil
Mtb 70SIC in complex with MtbEttA at Pre_R0 state
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Cui, Z, Zhang, J.
登録日2021-05-11
公開日2022-02-02
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis.
Nat Commun, 13, 2022
7FC9
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BU of 7fc9 by Molmil
Crystal structure of CmABCB1 in lipidic mesophase revealed by LCP-SFX
分子名称: ACETATE ION, CHLORIDE ION, MAGNESIUM ION, ...
著者Pan, D, Oyama, R, Sato, T, Nakane, T, Mizunuma, R, Matsuoka, K, Joti, Y, Tono, K, Nango, E, Iwata, S, Nakatsu, T, Kato, H.
登録日2021-07-14
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of CmABCB1 multi-drug exporter in lipidic mesophase revealed by LCP-SFX.
Iucrj, 9, 2022
7E1A
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BU of 7e1a by Molmil
Human bile salt exporter ABCB11 in complex with taurocholate
分子名称: Bile salt export pump, TAUROCHOLIC ACID
著者Wang, L, How, W.T, Chen, Y.
登録日2021-02-01
公開日2022-02-09
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献Structures of human bile acid exporter ABCB11 reveal a transport mechanism facilitated by two tandem substrate-binding pockets.
Cell Res., 32, 2022
7T56
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Cryo-EM structure of PCAT1 in the inward-facing intermediate conformation under ATP turnover condition
分子名称: ABC-type bacteriocin transporter, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Kieuvongngam, V, Chen, J.
登録日2021-12-11
公開日2022-02-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VGF
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BU of 7vgf by Molmil
cryo-EM structure of AMP-PNP bound human ABCB7
分子名称: Iron-sulfur clusters transporter ABCB7, mitochondrial, MAGNESIUM ION, ...
著者Yan, Q, Yang, X, Shen, Y.
登録日2021-09-16
公開日2022-02-16
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structure of AMP-PNP-bound human mitochondrial ATP-binding cassette transporter ABCB7.
J.Struct.Biol., 214, 2022
7EFO
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BU of 7efo by Molmil
LptB2FG-LPS from Klebsiella pneumoniae in nanodiscs
分子名称: (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, LPS export ABC transporter permease LptG, Lipopolysaccharide export system ATP-binding protein LptB, ...
著者Luo, Q, Shi, H.
登録日2021-03-22
公開日2022-03-02
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.85 Å)
主引用文献Cryo-EM structures of LptB 2 FG and LptB 2 FGC from Klebsiella pneumoniae in complex with lipopolysaccharide.
Biochem.Biophys.Res.Commun., 571, 2021
7NDF
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Crystal structure of nanobody Nb_MsbA#1 in complex with the nucleotide binding domain of MsbA
分子名称: Lipid A ABC transporter ATP-binding protein/permease MsbA, Nb_MsbA 1
著者Meier, G, Seeger, M.
登録日2021-02-01
公開日2022-03-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The ABC transporter MsbA adopts the wide inward-open conformation in E. coli cells.
Sci Adv, 8, 2022
7SEL
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E. coli MsbA in complex with LPS and inhibitor G7090 (compound 3)
分子名称: (2E)-3-{7-[(1S)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-1-methylnaphthalen-2-yl}prop-2-enoic acid, (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]-5-oxidanyl-oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, ATP-dependent lipid A-core flippase
著者Payandeh, J, Koth, C.M, Verma, V.A.
登録日2021-09-30
公開日2022-03-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.978 Å)
主引用文献Discovery of Inhibitors of the Lipopolysaccharide Transporter MsbA: From a Screening Hit to Potent Wild-Type Gram-Negative Activity.
J.Med.Chem., 65, 2022
7M69
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E1435Q Ycf1 mutant in inward-facing wide conformation
分子名称: Metal resistance protein YCF1
著者Khandelwal, N.K, Millan, C.R, Thaker, T.M, Tomasiak, T.M.
登録日2021-03-25
公開日2022-04-06
最終更新日2022-10-19
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献The structural basis for regulation of the glutathione transporter Ycf1 by regulatory domain phosphorylation.
Nat Commun, 13, 2022
7M68
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E1435Q Ycf1 mutant in inward-facing narrow conformation
分子名称: Metal resistance protein YCF1
著者Khandelwal, N.K, Millan, C.R, Thaker, T.M, Tomasiak, T.M.
登録日2021-03-25
公開日2022-04-06
最終更新日2022-10-19
実験手法ELECTRON MICROSCOPY (4.04 Å)
主引用文献The structural basis for regulation of the glutathione transporter Ycf1 by regulatory domain phosphorylation.
Nat Commun, 13, 2022
7TCH
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BU of 7tch by Molmil
BceAB E169Q variant ATP-bound conformation
分子名称: 4-amino-4-deoxy-1-O-[(S)-hydroxy{[(2E,6E,10Z,14Z,18Z,22E,26E,30E)-3,7,11,15,19,23,27,31,35-nonamethylhexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-yl]oxy}phosphoryl]-alpha-L-arabinopyranose, ADENOSINE-5'-TRIPHOSPHATE, Bacitracin export ATP-binding protein BceA, ...
著者George, N.L, Orlando, B.J.
登録日2021-12-23
公開日2022-04-06
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Conformational snapshots of the bacitracin sensing and resistance transporter BceAB.
Proc.Natl.Acad.Sci.USA, 119, 2022
7TCG
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BU of 7tcg by Molmil
BceAB nucleotide-free conformation
分子名称: 4-amino-4-deoxy-1-O-[(S)-hydroxy{[(2E,6E,10Z,14Z,18Z,22E,26E,30E)-3,7,11,15,19,23,27,31,35-nonamethylhexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-yl]oxy}phosphoryl]-alpha-L-arabinopyranose, Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB
著者George, N.L, Orlando, B.J.
登録日2021-12-23
公開日2022-04-06
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Conformational snapshots of the bacitracin sensing and resistance transporter BceAB.
Proc.Natl.Acad.Sci.USA, 119, 2022
7N5B
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BU of 7n5b by Molmil
Structure of AtAtm3 in the outward-facing conformation
分子名称: ABC transporter B family member 25, mitochondrial, ADENOSINE-5'-DIPHOSPHATE, ...
著者Fan, C, Rees, D.C.
登録日2021-06-05
公開日2022-04-13
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Glutathione binding to the plant At Atm3 transporter and implications for the conformational coupling of ABC transporters.
Elife, 11, 2022
7N58
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BU of 7n58 by Molmil
Structure of AtAtm3 in the inward-facing conformation
分子名称: ABC transporter B family member 25, mitochondrial
著者Fan, C, Rees, D.C.
登録日2021-06-05
公開日2022-04-13
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Glutathione binding to the plant At Atm3 transporter and implications for the conformational coupling of ABC transporters.
Elife, 11, 2022

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件を2024-07-10に公開中

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