1NUE
 
 | | X-RAY STRUCTURE OF NM23 HUMAN NUCLEOSIDE DIPHOSPHATE KINASE B COMPLEXED WITH GDP AT 2 ANGSTROMS RESOLUTION | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NUCLEOSIDE DIPHOSPHATE KINASE | | 著者 | Morera, S, Lacombe, M.-L, Yingwu, X, Lebras, G, Janin, J. | | 登録日 | 1995-10-06 | | 公開日 | 1996-04-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray structure of human nucleoside diphosphate kinase B complexed with GDP at 2 A resolution.
Structure, 3, 1995
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2WIO
 | | Structure of the histidine tagged, open cytochrome P450 Eryk from S. erythraea | | 分子名称: | ERYTHROMYCIN B/D C-12 HYDROXYLASE, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Savino, C, Montemiglio, L.C, Sciara, G, Miele, A.E, Kedrew, S.G, Gianni, S, Vallone, B. | | 登録日 | 2009-05-14 | | 公開日 | 2009-07-21 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Investigating the Structural Plasticity of a Cytochrome P450: Three-Dimensional Structures of P450 Eryk and Binding to its Physiological Substrate.
J.Biol.Chem., 284, 2009
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4DCV
 | | Crystal Structure of B. subtilis EngA in complex with GMPPCP | | 分子名称: | GTP-BINDING PROTEIN ENGA, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | | 著者 | Reiser, J.-B, Housset, D, Foucher, A.-E, Jault, J.-M. | | 登録日 | 2012-01-18 | | 公開日 | 2012-11-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Potassium Acts as a GTPase-Activating Element on Each Nucleotide-Binding Domain of the Essential Bacillus subtilis EngA.
Plos One, 7, 2012
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1O57
 | | CRYSTAL STRUCTURE OF THE PURINE OPERON REPRESSOR OF BACILLUS SUBTILIS | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEXAETHYLENE GLYCOL, NONAETHYLENE GLYCOL, ... | | 著者 | Sinha, S.C, Krahn, J, Shin, B.S, Tomchick, D.R, Zalkin, H, Smith, J.L. | | 登録日 | 2003-04-20 | | 公開日 | 2003-08-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The Purine Repressor of Bacillus Subtilis: A Novel Combination of Domains Adapted for Transcription Regulation
J.Bacteriol., 185, 2003
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1O9K
 | | Crystal structure of the retinoblastoma tumour suppressor protein bound to E2F peptide | | 分子名称: | RETINOBLASTOMA-ASSOCIATED PROTEIN, TRANSCRIPTION FACTOR E2F1 | | 著者 | Xiao, B, Spencer, J, Clements, A, Ali-Khan, N, Mittnacht, S, Broceno, C, Burghammer, M, Perrakis, A, Marmorstein, R, Gamblin, S.J. | | 登録日 | 2002-12-16 | | 公開日 | 2003-03-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of the Retinoblastoma Tumor Suppressor Protein Bound to E2F and the Molecular Basis of its Regulation
Proc.Natl.Acad.Sci.USA, 100, 2003
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1D67
 | | THE MOLECULAR STRUCTURE OF AN IDARUBICIN-D(TGATCA) COMPLEX AT HIGH RESOLUTION | | 分子名称: | DNA (5'-D(*TP*GP*AP*TP*CP*A)-3'), IDARUBICIN | | 著者 | Gallois, B, Langlois D'Estaintot, B, Brown, T, Hunter, W.N. | | 登録日 | 1992-03-31 | | 公開日 | 1993-07-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The structure of an idarubicin-d(TGATCA) complex at high resolution.
Acta Crystallogr.,Sect.D, 49, 1993
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6LML
 | | Cryo-EM structure of the human glucagon receptor in complex with Gi1 | | 分子名称: | Glucagon, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Qiao, A, Han, S, Li, X, Sun, F, Zhao, Q, Wu, B. | | 登録日 | 2019-12-26 | | 公開日 | 2020-04-01 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural basis of Gsand Girecognition by the human glucagon receptor.
Science, 367, 2020
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1I82
 | | FAMILY 9 CARBOHYDRATE-BINDING MODULE FROM THERMOTOGA MARITIMA XYLANASE 10A WITH CELLOBIOSE | | 分子名称: | CALCIUM ION, ENDO-1,4-BETA-XYLANASE A, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | | 著者 | Notenboom, V, Boraston, A.B, Warren, R.A.J, Kilburn, D.G, Rose, D.R. | | 登録日 | 2001-03-12 | | 公開日 | 2001-06-13 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structures of the family 9 carbohydrate-binding module from Thermotoga maritima xylanase 10A in native and ligand-bound forms.
Biochemistry, 40, 2001
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2V6Z
 | | Solution Structure of Amino-Terminal Domain of Human DNA Polymerase Epsilon Subunit B | | 分子名称: | DNA POLYMERASE EPSILON SUBUNIT 2 | | 著者 | Nuutinen, T, Fredriksson, K, Tossavainen, H, Pospiech, H, Pirila, P, Permi, P, Annila, A, Syvaoja, J.E. | | 登録日 | 2007-07-24 | | 公開日 | 2008-08-05 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Solution Structure of the Amino-Terminal Domain of Human DNA Polymerase Epsilon Subunit B is Homologous to C-Domains of Aaa+ Proteins.
Nucleic Acids Res., 36, 2008
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4NP4
 | | Clostridium difficile toxin B CROP domain in complex with FAB domains of neutralizing antibody bezlotoxumab | | 分子名称: | Toxin B, bezlotoxumab heavy chain, bezlotoxumab light chain | | 著者 | Orth, P, Xiao, L, Hernandez, L.D, Reichert, P, Sheth, P, Beaumont, M, Murgolo, N, Ermakov, G, DiNunzio, E, Racine, F, Karczewski, J, Secore, S, Ingram, R.N, Mayhood, T, Strickland, C, Therien, A.G. | | 登録日 | 2013-11-20 | | 公開日 | 2014-05-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Mechanism of Action and Epitopes of Clostridium difficile Toxin B-neutralizing Antibody Bezlotoxumab Revealed by X-ray Crystallography.
J.Biol.Chem., 289, 2014
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6LRZ
 | | Crystal structure of Keap1 in complex with dimethyl fumarate (DMF) | | 分子名称: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, ACETATE ION, Keap1-DC, ... | | 著者 | Padmanabhan, B, Unni, S, Deshmukh, P. | | 登録日 | 2020-01-16 | | 公開日 | 2020-08-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Structural insights into the multiple binding modes of Dimethyl Fumarate (DMF) and its analogs to the Kelch domain of Keap1.
Febs J., 288, 2021
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2BN1
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1Y7V
 | | X-ray structure of human acid-beta-glucosidase covalently bound to conduritol B epoxide | | 分子名称: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glucosylceramidase, ... | | 著者 | Premkumar, L, Sawkar, A.R, Boldin-Adamsky, S, Toker, L, Silman, I, Kelly, J.W, Futerman, A.H, Sussman, J.L, Israel Structural Proteomics Center (ISPC) | | 登録日 | 2004-12-10 | | 公開日 | 2005-04-12 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | X-ray structure of human acid-beta-glucosidase covalently bound to conduritol-B-epoxide. Implications for Gaucher disease.
J.Biol.Chem., 280, 2005
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4DCS
 | | Crystal Structure of B. subtilis EngA in complex with sulfate ion and GDP | | 分子名称: | GTP-BINDING PROTEIN ENGA, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION | | 著者 | Reiser, J.-B, Housset, D, Foucher, A.-E, Jault, J.-M. | | 登録日 | 2012-01-18 | | 公開日 | 2012-11-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Potassium Acts as a GTPase-Activating Element on Each Nucleotide-Binding Domain of the Essential Bacillus subtilis EngA.
Plos One, 7, 2012
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1YHU
 | | Crystal structure of Riftia pachyptila C1 hemoglobin reveals novel assembly of 24 subunits. | | 分子名称: | Giant hemoglobins B chain, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Flores, J.F, Fisher, C.R, Carney, S.L, Green, B.N, Freytag, J.K, Schaeffer, S.W, Royer, W.E. | | 登録日 | 2005-01-10 | | 公開日 | 2005-02-08 | | 最終更新日 | 2013-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Sulfide binding is mediated by zinc ions discovered in the crystal structure of a hydrothermal vent tubeworm hemoglobin.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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4DB4
 | | Mss116p DEAD-box helicase domain 2 bound to a chimaeric RNA-DNA duplex | | 分子名称: | 5'-R(*GP*GP*GP*CP*GP*GP*G)-D(P*CP*CP*CP*GP*CP*CP*C)-3', ATP-dependent RNA helicase MSS116, mitochondrial | | 著者 | Mallam, A.L, Del Campo, M, Gilman, B.D, Sidote, D.J, Lambowitz, A. | | 登録日 | 2012-01-13 | | 公開日 | 2012-08-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.599 Å) | | 主引用文献 | Structural basis for RNA-duplex recognition and unwinding by the DEAD-box helicase Mss116p.
Nature, 490, 2012
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1JH5
 | | Crystal Structure of sTALL-1 of TNF family ligand | | 分子名称: | TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13B | | 著者 | Liu, Y, Xu, L, Opalka, N, Shu, H.-B, Zhang, G. | | 登録日 | 2001-06-27 | | 公開日 | 2002-02-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands.
Cell(Cambridge,Mass.), 108, 2002
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4DCU
 | | Crystal Structure of B. subtilis EngA in complex with GDP | | 分子名称: | GTP-BINDING PROTEIN ENGA, GUANOSINE-5'-DIPHOSPHATE | | 著者 | Reiser, J.-B, Housset, D, Foucher, A.-E, Jault, J.-M. | | 登録日 | 2012-01-18 | | 公開日 | 2012-11-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Potassium Acts as a GTPase-Activating Element on Each Nucleotide-Binding Domain of the Essential Bacillus subtilis EngA.
Plos One, 7, 2012
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5VQZ
 | | Crystal Structure of HIV-1 Reverse Transcriptase (K103N, Y181C) Variant in Complex with 2-chloro-N-(6-cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl)-N-methylacetamide (JLJ686), a Non-nucleoside Inhibitor | | 分子名称: | N-(6-cyano-3-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}-4-methylnaphthalen-1-yl)-N-methylacetamide, Reverse transcriptase/ribonuclease H, SULFATE ION, ... | | 著者 | Buckingham, A.B, Chan, A.H, Anderson, K.S. | | 登録日 | 2017-05-09 | | 公開日 | 2017-08-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Covalent inhibitors for eradication of drug-resistant HIV-1 reverse transcriptase: From design to protein crystallography.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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3BL2
 | | Crystal Structure of M11, the BCL-2 Homolog of Murine Gamma-herpesvirus 68, Complexed with Mouse Beclin1 (residues 106-124) | | 分子名称: | Beclin-1, V-bcl-2 | | 著者 | Oh, B.-H, Woo, J.-S, Ku, B. | | 登録日 | 2007-12-10 | | 公開日 | 2008-02-12 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and Biochemical Bases for the Inhibition of Autophagy and Apoptosis by Viral BCL-2 of Murine gamma-Herpesvirus 68
Plos Pathog., 4, 2008
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4K5S
 | | The crystal structure of premithramycin B in complex with MTMOIV, a baeyer-villiger monooxygenase from the mithramycin biosynthetic pathway in streptomyces argillaceus. | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Oxygenase, premithramycin B | | 著者 | Noinaj, N, Bosserman, M.A, Rohr, J, Buchanan, S.K. | | 登録日 | 2013-04-15 | | 公開日 | 2013-10-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Molecular Insight into Substrate Recognition and Catalysis of Baeyer-Villiger Monooxygenase MtmOIV, the Key Frame-Modifying Enzyme in the Biosynthesis of Anticancer Agent Mithramycin.
Acs Chem.Biol., 8, 2013
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5VO3
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2GZM
 | | Crystal Structure of the Glutamate Racemase from Bacillus anthracis | | 分子名称: | D-GLUTAMIC ACID, Glutamate racemase | | 著者 | May, M, Santarsiero, B.D, Johnson, M.E, Mesecar, A.D. | | 登録日 | 2006-05-11 | | 公開日 | 2007-05-29 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structural and functional analysis of two glutamate racemase isozymes from Bacillus anthracis and implications for inhibitor design.
J.Mol.Biol., 371, 2007
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1RTC
 | | THE STRUCTURE OF RECOMBINANT RICIN A CHAIN AT 2.3 ANGSTROMS | | 分子名称: | RICIN | | 著者 | Mlsna, D, Monzingo, A.F, Katzin, B.J, Ernst, S, Robertus, J.D. | | 登録日 | 1992-10-29 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of recombinant ricin A chain at 2.3 A.
Protein Sci., 2, 1993
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1PXA
 | | CRYSTAL STRUCTURES OF MUTANT PSEUDOMONAS AERUGINOSA P-HYDROXYBENZOATE HYDROXYLASE: THE TYR201PHE, TYR385PHE, AND ASN300ASP VARIANTS | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE, P-HYDROXYBENZOIC ACID | | 著者 | Lah, M.S, Palfey, B.A, Schreuder, H.A, Ludwig, M.L. | | 登録日 | 1994-09-27 | | 公開日 | 1995-02-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structures of mutant Pseudomonas aeruginosa p-hydroxybenzoate hydroxylases: the Tyr201Phe, Tyr385Phe, and Asn300Asp variants.
Biochemistry, 33, 1994
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