PDB: 13252 件ウェブページステータス検索Chemie searchBIRD

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6R5D	Crystal structure of the Pri1 subunit of human primase bound to dATP 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA primase small subunit, ... 著者 Kilkenny, M.L, Pellegrini, L. 登録日 2019-03-24 公開日 2019-09-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine. Acs Chem.Biol., 14, 2019
6R4U	Crystal structure of the Pri1 subunit of human primase bound to fludarabine triphosphate 分子名称: 1,2-ETHANEDIOL, 2-fluoro-9-{5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}-9H-purin-6-a mine, DNA primase small subunit, ... 著者 Kilkenny, M.L, Pellegrini, L. 登録日 2019-03-24 公開日 2019-09-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine. Acs Chem.Biol., 14, 2019
6XEO	Structure of Mfd bound to dsDNA 分子名称: DNA (5'-D(P*AP*GP*GP*AP*TP*AP*CP*TP*TP*AP*CP*AP*GP*CP*CP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*GP*GP*CP*TP*GP*TP*AP*AP*GP*TP*AP*TP*CP*CP*T)-3'), Transcription-repair-coupling factor 著者 Brugger, C, Deaconescu, A. 登録日 2020-06-12 公開日 2020-08-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (5.5 Å) 主引用文献 Molecular determinants for dsDNA translocation by the transcription-repair coupling and evolvability factor Mfd. Nat Commun, 11, 2020
6PFJ	Structure of S. venezuelae RsiG-WhiG-(ci-di-GMP) complex, P64 crystal form 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), AmfC protein, RNA polymerase sigma factor 著者 Schumacher, M.A. 登録日 2019-06-21 公開日 2019-11-13 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 c-di-GMP Arms an Anti-sigma to Control Progression of Multicellular Differentiation in Streptomyces. Mol.Cell, 77, 2020
2PX5	Crystal structure of the Murray Valley Encephalitis Virus NS5 2'-O Methyltransferase domain in complex with SAH (Orthorhombic crystal form) 分子名称: Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)], S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION 著者 Assenberg, R, Ren, J, Verma, A, Walter, T.S, Alderton, D, Hurrelbrink, R.J, Fuller, S.D, Owens, R.J, Stuart, D.I, Grimes, J.M, Oxford Protein Production Facility (OPPF) 登録日 2007-05-14 公開日 2007-05-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues. J.Gen.Virol., 88, 2007
5V37	Crystal structure of SMYD3 with SAM and EPZ028862 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... 著者 Boriack-Sjodin, P.A. 登録日 2017-03-06 公開日 2018-03-07 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation. Plos One, 13, 2018
4L5G	Crystal structure of Thermus thermophilus CarD 分子名称: CarD 著者 Srivastava, D.B, Westblade, L.F, Campbell, E.A, Darst, S.A. 登録日 2013-06-11 公開日 2013-07-31 最終更新日 2013-08-21 実験手法 X-RAY DIFFRACTION (2.3902 Å) 主引用文献 Structure and function of CarD, an essential mycobacterial transcription factor. Proc.Natl.Acad.Sci.USA, 110, 2013
6R4S	Crystal structure of the Pri1 subunit of human primase bound to ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA primase small subunit, MANGANESE (II) ION, ... 著者 Kilkenny, M.L, Pellegrini, L. 登録日 2019-03-24 公開日 2019-09-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine. Acs Chem.Biol., 14, 2019
6R4T	Crystal structure of the Pri1 subunit of human primase bound to vidarabine triphosphate 分子名称: 1,2-ETHANEDIOL, 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}-9H-purin-6-amine, DNA primase small subunit, ... 著者 Kilkenny, M.L, Pellegrini, L. 登録日 2019-03-24 公開日 2019-09-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine. Acs Chem.Biol., 14, 2019
6RB4	Crystal structure of the Pri1 subunit of human primase 分子名称: 1,2-ETHANEDIOL, DNA primase small subunit, ZINC ION 著者 Kilkenny, M.L, Pellegrini, L. 登録日 2019-04-09 公開日 2019-09-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine. Acs Chem.Biol., 14, 2019
6R5E	Crystal structure of the Pri1 subunit of human primase bound to 2F-ATP 分子名称: 1,2-ETHANEDIOL, 2-fluoro-ATP, DNA primase small subunit, ... 著者 Kilkenny, M.L, Pellegrini, L. 登録日 2019-03-24 公開日 2019-09-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine. Acs Chem.Biol., 14, 2019
4N4H	Crystal structure of the Bromo-PWWP of the mouse zinc finger MYND-type containing 11 isoform alpha in complex with histone H3.1K36me3 分子名称: DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, Peptide from Histone H3.1, ... 著者 Li, Y, Ren, Y, Li, H. 登録日 2013-10-08 公開日 2014-03-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.302 Å) 主引用文献 ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression Nature, 508, 2014
2PX4	Crystal structure of the Murray Valley Encephalitis Virus NS5 2'-O Methyltransferase domain in complex with SAH (Monoclinic form 2) 分子名称: CHLORIDE ION, GLYCEROL, Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)], ... 著者 Assenberg, R, Ren, J, Verma, A, Walter, T.S, Alderton, D, Hurrelbrink, R.J, Fuller, S.D, Owens, R.J, Stuart, D.I, Grimes, J.M, Oxford Protein Production Facility (OPPF) 登録日 2007-05-14 公開日 2007-05-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues. J.Gen.Virol., 88, 2007
2PXA	Crystal structure of the Murray Valley Encephalitis Virus NS5 2'-O Methyltransferase domain in complex with SAH and GTPG 分子名称: GUANOSINE-5'-TRIPHOSPHATE, Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)], S-ADENOSYL-L-HOMOCYSTEINE 著者 Assenberg, R, Ren, J, Verma, A, Walter, T.S, Alderton, D, Hurrelbrink, R.J, Fuller, S.D, Owens, R.J, Stuart, D.I, Grimes, J.M, Oxford Protein Production Facility (OPPF) 登録日 2007-05-14 公開日 2007-05-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues. J.Gen.Virol., 88, 2007
2PX2	Crystal structure of the Murray Valley Encephalitis Virus NS5 2'-O Methyltransferase domain in complex with SAH (Monoclinic form 1) 分子名称: CHLORIDE ION, Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)], S-ADENOSYL-L-HOMOCYSTEINE 著者 Assenberg, R, Ren, J, Verma, A, Walter, T.S, Alderton, D, Hurrelbrink, R.J, Fuller, S.D, Owens, R.J, Stuart, D.I, Grimes, J.M, Oxford Protein Production Facility (OPPF) 登録日 2007-05-14 公開日 2007-05-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues. J.Gen.Virol., 88, 2007
6IC9	Crystal structure of the SPOC domain of human PHF3 in complex with RNA polymerase II CTD diheptapeptide phosphorylated on Ser2Ser7 分子名称: PHD finger protein 3, TYR-SEP-PRO-THR-SER-PRO-SEP-TYR-SEP-PRO-THR-SER-PRO 著者 Grishkovskaya, I, Djinovic-Carugo, K, Slade, D. 登録日 2018-12-03 公開日 2020-07-15 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (1.748 Å) 主引用文献 PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC Nat Commun, 12, 2021
2C5Z	Structure and CTD binding of the Set2 SRI domain 分子名称: SET DOMAIN PROTEIN 2 著者 Vojnic, E, Simon, B, Strahl, B.D, Sattler, M, Cramer, P. 登録日 2005-11-03 公開日 2005-11-14 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure and carboxyl-terminal domain (CTD) binding of the Set2 SRI domain that couples histone H3 Lys36 methylation to transcription. J. Biol. Chem., 281, 2006
2PX8	Crystal structure of the Murray Valley Encephalitis Virus NS5 2'-O Methyltransferase domain in complex with SAH and 7M-GTP 分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... 著者 Assenberg, R, Ren, J, Verma, A, Walter, T.S, Alderton, D, Hurrelbrink, R.J, Fuller, S.D, Owens, R.J, Stuart, D.I, Grimes, J.M, Oxford Protein Production Facility (OPPF) 登録日 2007-05-14 公開日 2007-05-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues. J.Gen.Virol., 88, 2007
2PXC	Crystal structure of the Murray Valley Encephalitis Virus NS5 2'-O Methyltransferase domain in complex with SAM and GTPA 分子名称: GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)], S-ADENOSYLMETHIONINE 著者 Assenberg, R, Ren, J, Verma, A, Walter, T.S, Alderton, D, Hurrelbrink, R.J, Fuller, S.D, Owens, R.J, Stuart, D.I, Grimes, J.M, Oxford Protein Production Facility (OPPF) 登録日 2007-05-14 公開日 2007-05-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues. J.Gen.Virol., 88, 2007
4N4I	Crystal structure of the Bromo-PWWP of the mouse zinc finger MYND-type containing 11 isoform alpha in complex with histone H3.3K36me3 分子名称: DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, Peptide from Histone H3.3, ... 著者 Li, Y, Ren, Y, Li, H. 登録日 2013-10-08 公開日 2014-03-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression Nature, 508, 2014
5DZM	HIV-1 Reverse Transcriptase RH domain 分子名称: Ribonuclease H 著者 Pedersen, L.C, London, R.E, Gabel, S.A, Zheng, X.H. 登録日 2015-09-25 公開日 2016-05-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Unfolding the HIV-1 reverse transcriptase RNase H domain - how to lose a molecular tug-of-war. Nucleic Acids Res., 44, 2016
5FVC	Structure of RNA-bound decameric HMPV nucleoprotein 分子名称: HMPV NUCLEOPROTEIN, RNA 著者 Renner, M, Bertinelli, M, Leyrat, C, Paesen, G.C, Saraiva de Oliveira, L.F, Huiskonen, J.T, Grimes, J.M. 登録日 2016-02-05 公開日 2016-02-24 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (4.17 Å) 主引用文献 Nucleocapsid assembly in pneumoviruses is regulated by conformational switching of the N protein. Elife, 5, 2016
6FSB	Influenza B/Memphis/13/03 endonuclease with I38T mutation 分子名称: MAGNESIUM ION, MANGANESE (II) ION, Polymerase acidic protein 著者 Cusack, S, Speranzini, V. 登録日 2018-02-19 公開日 2018-07-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci Rep, 8, 2018
4NQW	Structure of Mycobacterium tuberculosis extracytoplasmic function sigma factor SigK in complex with the cytosolic domain of its cognate anti-sigma factor RskA 分子名称: Anti-sigma-K factor RskA, CADMIUM ION, ECF RNA polymerase sigma factor SigK 著者 Shukla, J.K, Gopal, B. 登録日 2013-11-25 公開日 2014-01-22 最終更新日 2014-04-16 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for the redox sensitivity of the Mycobacterium tuberculosis SigK-RskA sigma-anti-sigma complex Acta Crystallogr.,Sect.D, 70, 2014
4TRQ	Crystal structure of Sac3/Thp1/Sem1 分子名称: 26S proteasome complex subunit SEM1, Nuclear mRNA export protein SAC3, Nuclear mRNA export protein THP1, ... 著者 Hellerschmied, D, Schneider, S, Kohler, A, Clausen, T. 登録日 2014-06-17 公開日 2015-08-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The Nuclear Pore-Associated TREX-2 Complex Employs Mediator to Regulate Gene Expression. Cell, 162, 2015

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