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9BVS
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BU of 9bvs by Molmil
NMR structure of TLP-1 in solution
分子名称: Temporin-1Tl
著者Jia, R, McShan, A.C.
登録日2024-05-20
公開日2024-06-05
実験手法SOLUTION NMR
主引用文献Design and Development of Temporin L Analogues to Inhibit the Main Protease of SARS-CoV-2
To Be Published
9BCZ
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BU of 9bcz by Molmil
Chicken 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (PLCZ1) in complex with calcium and phosphorylated threonine
分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ...
著者Edwards, M.M, Dong, A, Theo-Emegano, N, Seitova, A, Loppnau, P, Leung, R, Li, H, Ilyassov, O, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium, Structural Genomics Consortium (SGC)
登録日2024-04-10
公開日2024-05-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Chicken 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (PLCZ1) in complex with calcium and phosphorylated threonine
To be published
9B5W
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BU of 9b5w by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 1 map and model from cluster 5 (ATP/Mg)
分子名称: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Kochanczyk, T, Lima, C.D.
登録日2024-03-22
公開日2024-06-05
最終更新日2024-09-25
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
2IFG
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BU of 2ifg by Molmil
Structure of the extracellular segment of human TRKA in complex with nerve growth factor
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-nerve growth factor, High affinity nerve growth factor receptor, ...
著者He, X, Garcia, K.C.
登録日2006-09-20
公開日2007-02-13
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors.
Neuron, 53, 2007
9B5T
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BU of 9b5t by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - cluster 5 map and model (ATP/Mg)
分子名称: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Kochanczyk, T, Lima, C.D.
登録日2024-03-22
公開日2024-06-05
最終更新日2024-09-25
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
5JYX
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BU of 5jyx by Molmil
Crystal structure of the covalent thioimide intermediate of the archaeosine synthase QueF-Like
分子名称: 2-amino-5-[(Z)-iminomethyl]-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, Archeaosine synthase QueF-Like, SODIUM ION
著者Mei, X, Swairjo, M.A.
登録日2016-05-15
公開日2016-11-09
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Crystal structure of the archaeosine synthase QueF-like-Insights into amidino transfer and tRNA recognition by the tunnel fold.
Proteins, 85, 2017
9BB2
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BU of 9bb2 by Molmil
Backbone Modification in the GA Module of Protein PAB: beta3-residues at positions 20 and 24
分子名称: Peptostreptococcal albumin-binding protein
著者Lin, Y, Horne, W.S.
登録日2024-04-05
公開日2024-06-05
最終更新日2024-08-21
実験手法SOLUTION NMR
主引用文献Backbone Modification in a Protein Hydrophobic Core.
Chemistry, 30, 2024
9BOL
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BU of 9bol by Molmil
Crystal structure of the complex between VHL, ElonginB, ElonginC, and compound 5
分子名称: (4R)-1-[(2S)-2-(4-cyclopropyl-1H-1,2,3-triazol-1-yl)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}-L-prolinamide, 1,2-ETHANEDIOL, CHLORIDE ION, ...
著者Murray, J.M, Wu, H, Fuhrmann, J, Fairbrother, W.J, DiPasquale, A.
登録日2024-05-03
公開日2024-05-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Potency-Enhanced Peptidomimetic VHL Ligands with Improved Oral Bioavailability.
J.Med.Chem., 67, 2024
2II3
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BU of 2ii3 by Molmil
Crystal structure of a cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), Oxidized Coenzyme A-bound form
分子名称: ACETATE ION, CHLORIDE ION, Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, ...
著者Kato, M, Wynn, R.M, Chuang, J.L, Brautigam, C.A, Custorio, M, Chuang, D.T.
登録日2006-09-27
公開日2006-12-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complex.
Embo J., 25, 2006
9BB6
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BU of 9bb6 by Molmil
Backbone Modification in the GA Module of Protein PAB: ACPC residues at positions 5 and 13, beta3 residue at position 9
分子名称: Peptostreptococcal albumin-binding protein
著者Lin, Y, Horne, W.S.
登録日2024-04-05
公開日2024-06-05
最終更新日2024-08-21
実験手法SOLUTION NMR
主引用文献Backbone Modification in a Protein Hydrophobic Core.
Chemistry, 30, 2024
5K9X
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BU of 5k9x by Molmil
Crystal structure of Tryptophan synthase alpha chain from Legionella pneumophila subsp. pneumophila
分子名称: Tryptophan synthase alpha chain
著者Chang, C, Hatzos-Skintges, C, Endres, M, ANDERSON, W.F, JOACHIMIAK, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-06-01
公開日2016-06-15
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.016 Å)
主引用文献Crystal structure of Tryptophan synthase alpha chain from Legionella pneumophila subsp. pneumophila
To Be Published
9B59
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BU of 9b59 by Molmil
Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 5
分子名称: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ...
著者Kochanczyk, T, Lima, C.D.
登録日2024-03-22
公開日2024-06-05
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
2IIE
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BU of 2iie by Molmil
single chain Integration Host Factor protein (scIHF2) in complex with DNA
分子名称: DNA (5'-D(*DGP*DCP*DTP*DTP*DAP*DTP*DCP*DAP*DAP*DTP*DTP*DTP*DGP*DTP*DTP*DGP*DCP*DAP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DCP*DCP*DAP*DAP*DAP*DAP*DAP*DAP*DGP*DCP*DAP*DTP*DT)-3'), Integration host factor, ...
著者Bao, Q, Droege, P, Davey, C.A.
登録日2006-09-28
公開日2007-02-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献A Divalent Metal-mediated Switch Controlling Protein-induced DNA Bending
J.Mol.Biol., 367, 2007
9B58
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BU of 9b58 by Molmil
Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 4
分子名称: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ...
著者Kochanczyk, T, Lima, C.D.
登録日2024-03-22
公開日2024-06-05
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (3.39 Å)
主引用文献Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
5KA9
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BU of 5ka9 by Molmil
Protein Tyrosine Phosphatase 1B L192A mutant in complex with TCS401, open state
分子名称: 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
著者Choy, M.S, Peti, W, Page, R.
登録日2016-06-01
公開日2017-03-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
Mol. Cell, 65, 2017
6TR5
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BU of 6tr5 by Molmil
Melatonin-Notum complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide, ...
著者Zhao, Y, Jones, E.Y.
登録日2019-12-17
公開日2020-01-15
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.509 Å)
主引用文献Structural characterization of melatonin as an inhibitor of the Wnt deacylase Notum.
J. Pineal Res., 68, 2020
9B5D
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BU of 9b5d by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - Ub(T) class 1 map and model from consensus
分子名称: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, Large ribosomal subunit protein eL40B, ...
著者Kochanczyk, T, Lima, C.D.
登録日2024-03-22
公開日2024-06-05
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
5K02
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BU of 5k02 by Molmil
Structure of human SOD1 with T2D mutation
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Fay, J.M, Zhu, C, Cui, W, Ke, H, Dokholyan, N.V.
登録日2016-05-17
公開日2016-11-23
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献A Phosphomimetic Mutation Stabilizes SOD1 and Rescues Cell Viability in the Context of an ALS-Associated Mutation.
Structure, 24, 2016
1LDO
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BU of 1ldo by Molmil
avidin-norbioitn complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, NORBIOTIN, avidin
著者Pazy, Y, Kulik, T, Bayer, E.A, Wilchek, M, Livnah, O.
登録日2002-04-09
公開日2002-11-06
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Ligand exchange between proteins: exchange of biotin and biotin derivatives between avidin and streptavidin
J.Biol.Chem., 277, 2002
9B5K
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BU of 9b5k by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - Ub(T) class 1 map and model from cluster 1 (Ub(A)/ATP/Mg)
分子名称: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, Large ribosomal subunit protein eL40B, ...
著者Kochanczyk, T, Lima, C.D.
登録日2024-03-22
公開日2024-06-05
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9BB4
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BU of 9bb4 by Molmil
Backbone Modification in the GA Module of Protein PAB: beta3-residues at positions 23 and 26
分子名称: Peptostreptococcal albumin-binding protein
著者Lin, Y, Horne, W.S.
登録日2024-04-05
公開日2024-06-05
最終更新日2024-08-21
実験手法SOLUTION NMR
主引用文献Backbone Modification in a Protein Hydrophobic Core.
Chemistry, 30, 2024
9B57
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BU of 9b57 by Molmil
Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 3
分子名称: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ...
著者Kochanczyk, T, Lima, C.D.
登録日2024-03-22
公開日2024-06-05
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
2IND
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BU of 2ind by Molmil
Mn(II) Reconstituted Toluene/o-xylene Monooxygenase Hydroxylase X-ray Crystal Structure
分子名称: HEXAETHYLENE GLYCOL, MANGANESE (II) ION, Toluene, ...
著者McCormick, M.S, Sazinsky, M.H, Condon, K.L, Lippard, S.J.
登録日2006-10-06
公開日2006-12-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献X-ray crystal structures of manganese(II)-reconstituted and native toluene/o-xylene monooxygenase hydroxylase reveal rotamer shifts in conserved residues and an enhanced view of the protein interior.
J.Am.Chem.Soc., 128, 2006
9B5J
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BU of 9b5j by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - cluster 5 map and model (Ub(A)-AMP)
分子名称: 4-aminobutanenitrile, ADENOSINE MONOPHOSPHATE, Large ribosomal subunit protein eL40B, ...
著者Kochanczyk, T, Lima, C.D.
登録日2024-03-22
公開日2024-06-05
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5C
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BU of 9b5c by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - consensus map and model
分子名称: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, Large ribosomal subunit protein eL40B, ...
著者Kochanczyk, T, Lima, C.D.
登録日2024-03-22
公開日2024-06-05
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024

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件を2025-07-09に公開中

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