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5BUN
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BU of 5bun by Molmil
Crystal structure of an antigenic outer membrane protein ST50 from Salmonella Typhi
分子名称: Outer membrane protein, octyl beta-D-glucopyranoside
著者Yoshimura, M, Chuankhayan, P, Lin, C.C, Chen, N.C, Yang, M.C, Fun, H.K.
登録日2015-06-04
公開日2015-12-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Crystal structure of an antigenic outer-membrane protein from Salmonella Typhi suggests a potential antigenic loop and an efflux mechanism.
Sci Rep, 5, 2015
1Q75
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BU of 1q75 by Molmil
Solution structure of the dyskeratosis congenita mutant P2b hairpin from human telomerase RNA
分子名称: DKC mutant P2b telomerase RNA
著者Theimer, C.A, Finger, L.D, Feigon, J.
登録日2003-08-15
公開日2003-12-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献YNMG tetraloop formation by a dyskeratosis congenita mutation in human telomerase RNA.
Rna, 9, 2003
5JBL
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BU of 5jbl by Molmil
Structure of the bacteriophage T4 capsid assembly protease, gp21.
分子名称: Prohead core protein protease
著者Fokine, A, Rossmann, M.G.
登録日2016-04-13
公開日2016-12-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.943 Å)
主引用文献Common Evolutionary Origin of Procapsid Proteases, Phage Tail Tubes, and Tubes of Bacterial Type VI Secretion Systems.
Structure, 24, 2016
1QEZ
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BU of 1qez by Molmil
SULFOLOBUS ACIDOCALDARIUS INORGANIC PYROPHOSPHATASE: AN ARCHAEL PYROPHOSPHATASE.
分子名称: MAGNESIUM ION, PROTEIN (INORGANIC PYROPHOSPHATASE)
著者Leppanen, V.-M, Nummelin, H, Hansen, T, Lahti, R, Schafer, G, Goldman, A.
登録日1999-04-06
公開日1999-04-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Sulfolobus acidocaldarius inorganic pyrophosphatase: structure, thermostability, and effect of metal ion in an archael pyrophosphatase.
Protein Sci., 8, 1999
1Q87
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BU of 1q87 by Molmil
Crystal structure of the C-domain of the T.vaginalis Inr binding protein, IBP39 (tetragonal form)
分子名称: 39 kDa initiator binding protein
著者Schumacher, M.A, Johnson, P.J.
登録日2003-08-20
公開日2003-11-18
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structural Basis of Core Promoter Recognition in a Primitive Eukaryote
Cell(Cambridge,Mass.), 115, 2003
3C73
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BU of 3c73 by Molmil
Structure of CEHC variant ResA
分子名称: SULFATE ION, Thiol-disulfide oxidoreductase resA
著者Crow, A.
登録日2008-02-06
公開日2008-08-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Effects of substitutions in the CXXC active-site motif of the extracytoplasmic thioredoxin ResA.
Biochem.J., 414, 2008
1QGC
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BU of 1qgc by Molmil
STRUCTURE OF THE COMPLEX OF A FAB FRAGMENT OF A NEUTRALIZING ANTIBODY WITH FOOT AND MOUTH DISEASE VIRUS
分子名称: PROTEIN (GH-LOOP FROM VIRUS CAPSID PROTEIN VP1), PROTEIN (IMMUNOGLOBULIN HEAVY CHAIN), PROTEIN (IMMUNOGLOBULIN LIGHT CHAIN), ...
著者Fita, I.
登録日1999-04-23
公開日2000-01-26
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (30 Å)
主引用文献Structure of the complex of an Fab fragment of a neutralizing antibody with foot-and-mouth disease virus: positioning of a highly mobile antigenic loop.
EMBO J., 16, 1997
5JAI
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BU of 5jai by Molmil
Yersinia pestis FabV variant T276G
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ...
著者Pschibul, A, Kuper, J, HIrschbeck, M, Kisker, C.
登録日2016-04-12
公開日2016-05-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase.
Biochemistry, 55, 2016
3C7Z
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BU of 3c7z by Molmil
T4 lysozyme mutant D89A/R96H at room temperature
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme
著者Mooers, B.H.M.
登録日2008-02-08
公開日2009-02-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme.
Protein Sci., 18, 2009
3BOE
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BU of 3boe by Molmil
Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 2 with acetate (CDCA1-R2)
分子名称: ACETATE ION, CADMIUM ION, Cadmium-specific carbonic anhydrase
著者Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M.
登録日2007-12-17
公開日2008-01-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.
Nature, 452, 2008
1Q93
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BU of 1q93 by Molmil
Crystal structure of a mutant of the sarcin/ricin domain from rat 28S rRNA
分子名称: SODIUM ION, SULFATE ION, Sarcin/Ricin 28S rRNA
著者Correll, C.C, Beneken, J, Plantinga, M.J, Lubbers, M, Chan, Y.L.
登録日2003-08-22
公開日2003-11-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The common and distinctive features of the bulged-G motif based on a 1.04 A resolution RNA structure
Nucleic Acids Res., 31, 2003
5JCJ
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BU of 5jcj by Molmil
Trypanosoma brucei PTR1 in complex with inhibitor NMT-H037 (compound 7)
分子名称: 2-(3,4-dihydroxyphenyl)-3,6-dihydroxy-4H-1-benzopyran-4-one, ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Landi, G, Pozzi, C, Di Pisa, F, Dello Iacono, L, Mangani, S.
登録日2016-04-15
公開日2016-08-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs.
J.Med.Chem., 59, 2016
5JAU
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BU of 5jau by Molmil
Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered Through X-Ray Fragment Screening
分子名称: (2S)-3-(3-{[4-(2-aminoethoxy)-2',6-dimethyl[1,1'-biphenyl]-3-yl]amino}-1H-pyrazol-1-yl)-2-methoxypropan-1-ol, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Day, P.J.
登録日2016-04-12
公開日2016-05-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment Screening.
J.Med.Chem., 59, 2016
5JB4
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BU of 5jb4 by Molmil
A simplified BPTI variant containing 21 alanines out 58 of residues
分子名称: Pancreatic trypsin inhibitor, SULFATE ION
著者Islam, M.M.
登録日2016-04-13
公開日2017-04-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Crystal structures of highly simplified BPTIs provide insights into hydration-driven increase of unfolding enthalpy
Sci Rep, 7, 2017
5BPY
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BU of 5bpy by Molmil
Crystal structure of bruton agammaglobulinemia tyrosine kinase complexed with BMS-824171 AKA 6-[(3R)-3-(4-tert-bu tylbenzamido)piperidin-1-yl]-2-{[4-(morpholine-4-carbonyl) phenyl]amino}pyridine-3-carboxamide
分子名称: 6-{(3R)-3-[(4-tert-butylbenzoyl)amino]piperidin-1-yl}-2-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}pyridine-3-carboxamide, Tyrosine-protein kinase BTK
著者Muckelbauer, J.K.
登録日2015-05-28
公開日2015-09-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Design and synthesis of carbazole carboxamides as promising inhibitors of Bruton's tyrosine kinase (BTK) and Janus kinase 2 (JAK2).
Bioorg.Med.Chem.Lett., 25, 2015
1QIK
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BU of 1qik by Molmil
SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT H) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE
分子名称: ACETYLCHOLINESTERASE
著者Kryger, G, Weik, M, Ravelli, R.B.G.
登録日1999-06-14
公開日2000-01-28
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Specific chemical and structural damage to proteins produced by synchrotron radiation.
Proc.Natl.Acad.Sci.USA, 97, 2000
8H9H
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BU of 8h9h by Molmil
Crystal structure of ZBTB7A in complex with GACCC-containing sequence
分子名称: DNA (5'-D(*TP*AP*AP*GP*GP*AP*CP*CP*CP*AP*GP*AP*T)-3'), DNA (5'-D(P*AP*AP*TP*CP*TP*GP*GP*GP*TP*CP*CP*TP*T)-3'), ZINC ION, ...
著者Yang, Y.
登録日2022-10-25
公開日2023-04-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献ZBTB7A regulates primed-to-naive transition of pluripotent stem cells via recognition of the PNT-associated sequence by zinc fingers 1-2 and recognition of gamma-globin -200 gene element by zinc fingers 1-4.
Febs J., 290, 2023
1QA6
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BU of 1qa6 by Molmil
CRYSTAL STRUCTURE OF A CONSERVED RIBOSOMAL PROTEIN-RNA COMPLEX
分子名称: 58 NUCLEOTIDE RIBOSOMAL RNA DOMAIN, MAGNESIUM ION, OSMIUM ION, ...
著者Conn, G.L, Draper, D.E, Lattman, E.E, Gittis, A.G.
登録日1999-04-15
公開日1999-05-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of a conserved ribosomal protein-RNA complex.
Science, 284, 1999
5JDE
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BU of 5jde by Molmil
Crystal structure of I9-I11 tandem from titin (P1)
分子名称: Titin
著者Williams, R, Bogomolovas, J, Labiet, S, Mayans, O.
登録日2016-04-16
公開日2016-09-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Exploration of pathomechanisms triggered by a single-nucleotide polymorphism in titin's I-band: the cardiomyopathy-linked mutation T2580I.
Open Biology, 6, 2016
5JEG
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BU of 5jeg by Molmil
Human carbonic anhydrase II (V121I) complexed with benzo[d]thiazole-2-sulfonamide
分子名称: 1,3-benzothiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION
著者Fox, J.M, Kang, K, Sastry, M, Sherman, W, Sankaran, B, Zwart, P.H, Whitesides, G.M.
登録日2016-04-18
公開日2017-01-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase.
Angew. Chem. Int. Ed. Engl., 56, 2017
3BK3
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BU of 3bk3 by Molmil
Crystal structure of the complex of BMP-2 and the first Von Willebrand domain type C of Crossveinless-2
分子名称: Bone morphogenetic protein 2, Crossveinless 2
著者Mueller, T.D, Sebald, W, Zhang, J.-L.
登録日2007-12-05
公開日2008-05-27
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure analysis reveals how the Chordin family member crossveinless 2 blocks BMP-2 receptor binding
Dev.Cell, 14, 2008
5J2T
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BU of 5j2t by Molmil
Tubulin-vinblastine complex
分子名称: (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
著者Waight, A.B, Bargsten, K, Doronina, S, Steinmetz, M.O, Sussman, D, Prota, A.E.
登録日2016-03-30
公開日2016-08-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis of Microtubule Destabilization by Potent Auristatin Anti-Mitotics.
Plos One, 11, 2016
5JEP
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BU of 5jep by Molmil
Human carbonic anhydrase II (T199S) complexed with benzo[d]thiazole-2-sulfonamide
分子名称: 1,3-benzothiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION
著者Fox, J.M, Kang, K, Sastry, M, Sherman, W, Sankaran, B, Zwart, P.H, Whitesides, G.M.
登録日2016-04-18
公開日2017-01-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase.
Angew. Chem. Int. Ed. Engl., 56, 2017
1QKK
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BU of 1qkk by Molmil
Crystal structure of the receiver domain and linker region of DctD from Sinorhizobium meliloti
分子名称: C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN
著者Meyer, M.G, Park, S, Zeringue, L, Staley, M, Mckinstry, M, Kaufman, R.I, Zhang, H, Yan, D, Yennawar, N, Farber, G.K, Nixon, B.T.
登録日1999-07-23
公開日2000-07-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A dimeric two-component receiver domain inhibits the sigma54-dependent ATPase in DctD.
Faseb J., 15, 2001
5AWH
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BU of 5awh by Molmil
Rhodobacter sphaeroides Argonaute in complex with guide RNA/target DNA heteroduplex
分子名称: DNA (5'-D(*CP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*A)-3'), MAGNESIUM ION, RNA (5'-D(P*UP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3'), ...
著者Miyoshi, T, Ito, K, Murakami, R, Uchiumi, T.
登録日2015-07-03
公開日2016-07-06
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the recognition of guide RNA and target DNA heteroduplex by Argonaute.
Nat Commun, 7, 2016

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