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4E5L
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BU of 4e5l by Molmil
Crystal structure of avian influenza virus PAn bound to compound 6
分子名称: 2,3-DIHYDROXY-BENZOIC ACID, MANGANESE (II) ION, Polymerase protein PA, ...
著者DuBois, R.M, Slavish, P.J, Webb, T.R, White, S.W.
登録日2012-03-14
公開日2012-08-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.469 Å)
主引用文献Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease.
Plos Pathog., 8, 2012
4E5H
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BU of 4e5h by Molmil
Crystal structure of avian influenza virus PAn bound to compound 3
分子名称: (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, MANGANESE (II) ION, Polymerase protein PA, ...
著者DuBois, R.M, Slavish, P.J, Webb, T.R, White, S.W.
登録日2012-03-14
公開日2012-08-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.158 Å)
主引用文献Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease.
Plos Pathog., 8, 2012
4E5G
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BU of 4e5g by Molmil
Crystal structure of avian influenza virus PAn bound to compound 2
分子名称: 2-4-DIOXO-4-PHENYLBUTANOIC ACID, MANGANESE (II) ION, Polymerase protein PA, ...
著者DuBois, R.M, Slavish, P.J, Webb, T.R, White, S.W.
登録日2012-03-14
公開日2012-08-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.647 Å)
主引用文献Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease.
Plos Pathog., 8, 2012
4E5E
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BU of 4e5e by Molmil
Crystal structure of avian influenza virus PAn Apo
分子名称: MANGANESE (II) ION, Polymerase protein PA, SULFATE ION
著者DuBois, R.M, White, S.W.
登録日2012-03-14
公開日2012-08-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.048 Å)
主引用文献Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease.
Plos Pathog., 8, 2012
4E5F
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BU of 4e5f by Molmil
Crystal structure of avian influenza virus PAn bound to compound 1
分子名称: 2-hydroxyisoquinoline-1,3(2H,4H)-dione, MANGANESE (II) ION, Polymerase protein PA, ...
著者DuBois, R.M, Slavish, P.J, Webb, T.R, White, S.W.
登録日2012-03-14
公開日2012-08-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.392 Å)
主引用文献Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease.
Plos Pathog., 8, 2012
4E5I
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BU of 4e5i by Molmil
Crystal structure of avian influenza virus PAn bound to compound 4
分子名称: 5-hydroxy-2-(1-methyl-1H-imidazol-4-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid, MANGANESE (II) ION, Polymerase protein PA, ...
著者DuBois, R.M, Slavish, P.J, Webb, T.R, White, S.W.
登録日2012-03-14
公開日2012-08-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.944 Å)
主引用文献Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease.
Plos Pathog., 8, 2012
7KTR
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BU of 7ktr by Molmil
Cryo-EM structure of the human SAGA coactivator complex (TRRAP, core)
分子名称: Ataxin-7, INOSITOL HEXAKISPHOSPHATE, Isoform 3 of Transcription factor SPT20 homolog, ...
著者Herbst, D.A, Esbin, M.N, Nogales, E.
登録日2020-11-24
公開日2021-11-10
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Structure of the human SAGA coactivator complex.
Nat.Struct.Mol.Biol., 28, 2021
7K5I
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BU of 7k5i by Molmil
SARS-COV-2 nsp1 in complex with human 40S ribosome
分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
著者Wang, L, Shi, M, Wu, H.
登録日2020-09-16
公開日2020-10-14
最終更新日2021-03-17
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism.
Biorxiv, 2020
3VU3
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BU of 3vu3 by Molmil
Crystal structure of the Hfq and catalase HPII complex
分子名称: Catalase HPII, PROTOPORPHYRIN IX CONTAINING FE, Protein hfq
著者Watanabe, M, Yonekura, K.
登録日2012-06-15
公開日2013-11-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Post-Transcriptional Regulator Hfq Binds Catalase HPII: Crystal Structure of the Complex
Plos One, 8, 2013
6FS7
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BU of 6fs7 by Molmil
Influenza A/California/04/2009 (pH1N1) endonuclease with I38T mutation with bound inhibitor, baloxavir acid (BXA)
分子名称: Baloxavir acid, MANGANESE (II) ION, Polymerase acidic protein,Polymerase acidic protein
著者Cusack, S, Speranzini, V.
登録日2018-02-19
公開日2018-07-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil.
Sci Rep, 8, 2018
6WIQ
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BU of 6wiq by Molmil
Crystal structure of the co-factor complex of NSP7 and the C-terminal domain of NSP8 from SARS CoV-2
分子名称: Non-structural protein 7, Non-structural protein 8
著者Wilamowski, M, Kim, Y, Jedrzejczak, R, Maltseva, N, Endres, M, Godzik, A, Michalska, K, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-04-10
公開日2020-04-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication.
Biophys.J., 120, 2021
6WQD
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BU of 6wqd by Molmil
The 1.95 A Crystal Structure of the Co-factor Complex of NSP7 and the C-terminal Domain of NSP8 from SARS-CoV-2
分子名称: 1,2-ETHANEDIOL, Non-structural protein 7, Non-structural protein 8
著者Kim, Y, Wilamowski, M, Jedrzejczak, R, Maltseva, N, Endres, M, Godzik, A, Michalska, K, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-04-28
公開日2020-05-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication.
Biophys.J., 120, 2021
6XIP
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BU of 6xip by Molmil
The 1.5 A Crystal Structure of the Co-factor Complex of NSP7 and the C-terminal Domain of NSP8 from SARS CoV-2
分子名称: 1,2-ETHANEDIOL, Non-structural protein 7, Non-structural protein 8
著者Wilamowski, M, Kim, Y, Jedrzejczak, R, Maltseva, N, Endres, M, Godzik, A, Michalska, K, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-06-20
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication.
Biophys.J., 120, 2021
5MG2
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BU of 5mg2 by Molmil
Crystal structure of the second bromodomain of human TAF1 in complex with BAY-299 chemical probe
分子名称: 1,2-ETHANEDIOL, 6-(3-oxidanylpropyl)-2-(1,3,6-trimethyl-2-oxidanylidene-benzimidazol-5-yl)benzo[de]isoquinoline-1,3-dione, Transcription initiation factor TFIID subunit 1
著者Tallant, C, Bouche, L, Holton, S.J, Fedorov, O, Siejka, P, Picaud, S, Krojer, T, Srikannathasan, V, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hartung, I.V, Haendler, B, Muller, S, Huber, K.V.M, Structural Genomics Consortium (SGC)
登録日2016-11-20
公開日2017-05-03
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains.
J. Med. Chem., 60, 2017
2FQM
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BU of 2fqm by Molmil
Crystal structure of the oligomerization domain of the phosphoprotein of vesicular stomatitis virus
分子名称: Phosphoprotein
著者Ding, H, Green, T.J, Lu, S, Luo, M.
登録日2006-01-18
公開日2006-02-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the oligomerization domain of the phosphoprotein of vesicular stomatitis virus
J.Virol., 80, 2006
6FS6
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BU of 6fs6 by Molmil
Influenza A/California/04/2009 (pH1N1) endonuclease with bound inhibitor, baloxavir acid (BXA)
分子名称: Baloxavir acid, MANGANESE (II) ION, Polymerase acidic protein,Polymerase acidic protein
著者Cusack, S, Speranzini, V.
登録日2018-02-19
公開日2018-07-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.291 Å)
主引用文献Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil.
Sci Rep, 8, 2018
2ETN
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BU of 2etn by Molmil
Crystal structure of Thermus aquaticus Gfh1
分子名称: anti-cleavage anti-GreA transcription factor Gfh1
著者Lamour, V, Hogan, B.P, Erie, D.A, Darst, S.A.
登録日2005-10-27
公開日2006-02-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of Thermus aquaticus Gfh1, a Gre-factor paralog that inhibits rather than stimulates transcript cleavage.
J.Mol.Biol., 356, 2006
6TB4
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BU of 6tb4 by Molmil
Structure of SAGA bound to TBP
分子名称: SAGA-associated factor 73 (Sgf73), Spt20, Subunit (17 kDa) of TFIID and SAGA complexes, ...
著者Papai, G, Frechard, A, Kolesnikova, O, Crucifix, C, Schultz, P, Ben-Shem, A.
登録日2019-10-31
公開日2020-01-29
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of SAGA and mechanism of TBP deposition on gene promoters.
Nature, 577, 2020
1VPT
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BU of 1vpt by Molmil
AS11 VARIANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYL-L-METHIONINE
分子名称: S-ADENOSYLMETHIONINE, VP39
著者Hodel, A.E, Gershon, P.D, Shi, X, Quiocho, F.A.
登録日1996-03-20
公開日1996-08-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The 1.85 A structure of vaccinia protein VP39: a bifunctional enzyme that participates in the modification of both mRNA ends.
Cell(Cambridge,Mass.), 85, 1996
5G5P
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BU of 5g5p by Molmil
Structure of the Saccharomyces cerevisiae TREX-2 complex
分子名称: 26S PROTEASOME COMPLEX SUBUNIT SEM1, NUCLEAR MRNA EXPORT PROTEIN SAC3, NUCLEAR MRNA EXPORT PROTEIN THP1
著者Aibara, S, Bai, X.C, Stewart, M.
登録日2016-05-26
公開日2016-11-23
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献The Sac3 Tpr-Like Region in the Saccharomyces Cerevisiae Trex-2 Complex is More Extensive But Independent of the Cid Region
J.Struct.Biol., 195, 2016
2HMI
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BU of 2hmi by Molmil
HIV-1 REVERSE TRANSCRIPTASE/FRAGMENT OF FAB 28/DNA COMPLEX
分子名称: DNA (5'-D(*AP*TP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*A)-3'), FAB FRAGMENT OF MONOCLONAL ANTIBODY 28, ...
著者Ding, J, Arnold, E.
登録日1998-04-10
公開日1998-10-14
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution.
J.Mol.Biol., 284, 1998
8BGU
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BU of 8bgu by Molmil
human MDM2-5S RNP
分子名称: 5S rRNA, 60S ribosomal protein L11, 60S ribosomal protein L5, ...
著者Castillo, N, Thoms, M, Flemming, D, Hammaren, H.M, Buschauer, R, Ameismeier, M, Bassler, J, Beck, M, Beckmann, R, Hurt, E.
登録日2022-10-28
公開日2023-06-14
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structure of nascent 5S RNPs at the crossroad between ribosome assembly and MDM2-p53 pathways.
Nat.Struct.Mol.Biol., 30, 2023
6P1B
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BU of 6p1b by Molmil
Transcription antitermination factor Q21
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Q protein
著者Yin, Z, Ebright, R.H.
登録日2019-05-19
公開日2019-06-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.942 Å)
主引用文献Structural basis of Q-dependent antitermination.
Proc.Natl.Acad.Sci.USA, 116, 2019
6GIS
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BU of 6gis by Molmil
Structural basis of human clamp sliding on DNA
分子名称: DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), Proliferating cell nuclear antigen
著者De March, M, Merino, N, Barrera-Vilarmau, S, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A.
登録日2018-05-15
公開日2018-05-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Structural basis of human PCNA sliding on DNA.
Nat Commun, 8, 2017
6P1A
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BU of 6p1a by Molmil
Transcription antitermination factor Q21 in complex with Q21-binding-element DNA
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(*CP*TP*TP*GP*CP*TP*CP*AP*TP*TP*TP*GP*CP*TP*CP*AP*AP*TP*GP*AP*G)-3'), ...
著者Yin, Z, Ebright, R.H.
登録日2019-05-19
公開日2019-06-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.837 Å)
主引用文献Structural basis of Q-dependent antitermination.
Proc.Natl.Acad.Sci.USA, 116, 2019

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