6WQD

The 1.95 A Crystal Structure of the Co-factor Complex of NSP7 and the C-terminal Domain of NSP8 from SARS-CoV-2

Summary for 6WQD

• Entry DOI: 10.2210/pdb6wqd/pdb
• Related: 6WIQ
• Descriptor: Non-structural protein 7, Non-structural protein 8, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: sars cov-2, co-factor for rna polymerase nsp12, structural genomics, center for structural genomics of infectious diseases, csgid, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 4
• Total formula weight: 46259.39

Authors

Kim, Y.,Wilamowski, M.,Jedrzejczak, R.,Maltseva, N.,Endres, M.,Godzik, A.,Michalska, K.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2020-04-28, release date: 2020-05-06, Last modification date: 2023-10-18)

• Primary citation: Wilamowski, M.,Hammel, M.,Leite, W.,Zhang, Q.,Kim, Y.,Weiss, K.L.,Jedrzejczak, R.,Rosenberg, D.J.,Fan, Y.,Wower, J.,Bierma, J.C.,Sarker, A.H.,Tsutakawa, S.E.,Pingali, S.V.,O'Neill, H.M.,Joachimiak, A.,Hura, G.L.; Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication.; Biophys.J., 120:3152-3165, 2021; PubMed: 34197805; DOI: 10.1016/j.bpj.2021.06.006

Experimental method

X-RAY DIFFRACTION (1.95 Å)