6WIQ
Crystal structure of the co-factor complex of NSP7 and the C-terminal domain of NSP8 from SARS CoV-2
Summary for 6WIQ
Entry DOI | 10.2210/pdb6wiq/pdb |
Descriptor | Non-structural protein 7, Non-structural protein 8 (2 entities in total) |
Functional Keywords | sars cov-2, co-factor for rna polymerase nsp12, structural genomics, center for structural genomics of infectious diseases, csgid, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 2 |
Total formula weight | 23036.59 |
Authors | Wilamowski, M.,Kim, Y.,Jedrzejczak, R.,Maltseva, N.,Endres, M.,Godzik, A.,Michalska, K.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2020-04-10, release date: 2020-04-22, Last modification date: 2023-10-18) |
Primary citation | Wilamowski, M.,Hammel, M.,Leite, W.,Zhang, Q.,Kim, Y.,Weiss, K.L.,Jedrzejczak, R.,Rosenberg, D.J.,Fan, Y.,Wower, J.,Bierma, J.C.,Sarker, A.H.,Tsutakawa, S.E.,Pingali, S.V.,O'Neill, H.M.,Joachimiak, A.,Hura, G.L. Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication. Biophys.J., 120:3152-3165, 2021 Cited by PubMed: 34197805DOI: 10.1016/j.bpj.2021.06.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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