PDB: 13252 件ウェブページステータス検索Chemie searchBIRD

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5N63	Crystal Structure of p38alpha in Complex with Lipid Pocket Ligand 9c 分子名称: Mitogen-activated protein kinase 14, ~{N}4-[(4-fluorophenyl)methyl]-2-phenyl-quinazoline-4,7-diamine 著者 Buehrmann, M, Mueller, M.P, Rauh, D. 登録日 2017-02-14 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38 alpha MAPK. PLoS ONE, 12, 2017
5N66	Crystal Structure of p38alpha in Complex with Lipid Pocket Ligand 9j 分子名称: 1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA, Mitogen-activated protein kinase 14, ~{N}4-[[4-(cyclopropylmethyl)furan-2-yl]methyl]-2-phenyl-quinazoline-4,7-diamine 著者 Buehrmann, M, Mueller, M.P, Wiedemann, B, Rauh, D. 登録日 2017-02-14 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38 alpha MAPK. PLoS ONE, 12, 2017
3JCR	3D structure determination of the human*U4/U6.U5* tri-snRNP complex 分子名称: LSm2, LSm3, LSm4, ... 著者 Agafonov, D.E, Kastner, B, Dybkov, O, Hofele, R.V, Liu, W.T, Urlaub, H, Luhrmann, R, Stark, H. 登録日 2016-01-21 公開日 2016-03-09 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (7 Å) 主引用文献 Molecular architecture of the human U4/U6.U5 tri-snRNP. Science, 351, 2016
4KRF	Structure of Human Argonaute-1 let-7 complex 分子名称: Protein argonaute-1, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*UP*U)-3') 著者 Faehnle, C.R, Elkayam, E, Joshua-Tor, L. 登録日 2013-05-16 公開日 2013-06-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.101 Å) 主引用文献 The making of a slicer: activation of human argonaute-1. Cell Rep, 3, 2013
4F3T	Human Argonaute-2 - miR-20a complex 分子名称: PHENOL, Protein argonaute-2, RNA (5'-R(P*UP*AP*AP*AP*GP*UP*GP*CP*UP*UP*AP*UP*AP*GP*UP*G*CP*AP*GP*G)-3') 著者 Elkayam, E, Kuhn, C.-D, Tocilj, A, Joshua-Tor, L. 登録日 2012-05-09 公開日 2012-05-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 The Structure of Human Argonaute-2 in Complex with miR-20a. Cell(Cambridge,Mass.), 150, 2012
1N52	Cap Binding Complex 分子名称: 20 kDa nuclear cap binding protein, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, 80 kDa nuclear cap binding protein, ... 著者 Calero, G, Wilson, K, Ly, T, Rios-Steiner, J, Clardy, J, Cerione, R. 登録日 2002-11-04 公開日 2003-02-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Structural basis of m7GpppG binding to the nuclear cap-binding protein complex. Nat.Struct.Biol., 9, 2002
8CLJ	TFIIIC TauB-DNA dimer 分子名称: General transcription factor 3C polypeptide 1, General transcription factor 3C polypeptide 2, General transcription factor 3C polypeptide 4, ... 著者 Seifert-Davila, W, Girbig, M, Hauptmann, L, Hoffmann, T, Eustermann, S, Mueller, C.W. 登録日 2023-02-16 公開日 2023-06-21 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural insights into human TFIIIC promoter recognition. Sci Adv, 9, 2023
8CLL	Structural insights into human TFIIIC promoter recognition 分子名称: General transcription factor 3C polypeptide 1, General transcription factor 3C polypeptide 2, General transcription factor 3C polypeptide 4, ... 著者 Seifert-Davila, W, Girbig, M, Hauptmann, L, Hoffmann, T, Eustermann, S, Mueller, C.W. 登録日 2023-02-16 公開日 2023-06-21 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural insights into human TFIIIC promoter recognition. Sci Adv, 9, 2023
5EG7	The cap binding site of influenza virus protein PB2 as a drug target 分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, GLYCEROL, Polymerase basic protein 2 著者 Severin, C, Rocha de Moura, T, Liu, Y, Li, K, Zheng, X, Luo, M. 登録日 2015-10-26 公開日 2016-02-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 The cap-binding site of influenza virus protein PB2 as a drug target. Acta Crystallogr D Struct Biol, 72, 2016
7EGF	TFIID lobe A subcomplex 分子名称: TATA-box-binding protein, Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID subunit 11, ... 著者 Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. 登録日 2021-03-24 公開日 2021-05-05 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.16 Å) 主引用文献 Structural insights into preinitiation complex assembly on core promoters. Science, 2021
8CLI	TFIIIC TauB-DNA monomer 分子名称: DNA (35-MER), General transcription factor 3C polypeptide 1, General transcription factor 3C polypeptide 2, ... 著者 Seifert-Davila, W, Girbig, M, Hauptmann, L, Hoffmann, T, Eustermann, S, Mueller, C.W. 登録日 2023-02-16 公開日 2023-06-21 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural insights into human TFIIIC promoter recognition. Sci Adv, 9, 2023
7N9F	Structure of the in situ yeast NPC 分子名称: Dynein light chain 1, cytoplasmic, Nucleoporin 145c, ... 著者 Villa, E, Singh, D, Ludtke, S.J, Akey, C.W, Rout, M.P, Echeverria, I, Suslov, S. 登録日 2021-06-17 公開日 2022-01-26 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (37 Å) 主引用文献 Comprehensive structure and functional adaptations of the yeast nuclear pore complex. Cell, 185, 2022
7KJX	Structure of HIV-1 reverse transcriptase initiation complex core with nevirapine 分子名称: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 viral RNA fragment, MAGNESIUM ION, ... 著者 Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V. 登録日 2020-10-26 公開日 2021-03-17 最終更新日 2021-05-12 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs. Nat Commun, 12, 2021
7KJV	Structure of HIV-1 reverse transcriptase initiation complex core 分子名称: HIV-1 viral RNA fragment, MAGNESIUM ION, Reverse transcriptase/ribonuclease H, ... 著者 Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V. 登録日 2020-10-26 公開日 2021-03-17 最終更新日 2021-05-12 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs. Nat Commun, 12, 2021
7KJW	Structure of HIV-1 reverse transcriptase initiation complex core with efavirenz 分子名称: (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE, HIV-1 viral RNA fragment, MAGNESIUM ION, ... 著者 Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V. 登録日 2020-10-26 公開日 2021-03-17 最終更新日 2021-05-12 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs. Nat Commun, 12, 2021
6CBD	Crystal Structure of Human Argonaute2 Bound to Three Tryptophans 分子名称: Guide RNA, ISOPROPYL ALCOHOL, MAGNESIUM ION, ... 著者 Sheu-Gruttadauria, J, MacRae, I.J. 登録日 2018-02-02 公開日 2018-04-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.203 Å) 主引用文献 Phase Transitions in the Assembly and Function of Human miRISC. Cell, 173, 2018
2DR8	Complex structure of CCA-adding enzyme with tRNAminiDC and CTP 分子名称: CCA-adding enzyme, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Tomita, K, Ishitani, R, Fukai, S, Nureki, O. 登録日 2006-06-08 公開日 2006-11-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Complete crystallographic analysis of the dynamics of CCA sequence addition Nature, 443, 2006
2DR9	Complex structure of CCA-adding enzyme with tRNAminiDCC 分子名称: CCA-adding enzyme, SULFATE ION, tRNA (34-MER) 著者 Tomita, K, Ishitani, R, Fukai, S, Nureki, O. 登録日 2006-06-08 公開日 2006-11-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Complete crystallographic analysis of the dynamics of CCA sequence addition Nature, 443, 2006
7EGH	TFIID lobe C subcomplex 分子名称: DNA (45-MER), Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 2, ... 著者 Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. 登録日 2021-03-24 公開日 2021-05-12 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
3K5M	Crystal structure of E.coli Pol II-abasic DNA-ddGTP Lt(-2, 2) ternary complex 分子名称: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*TP*CP*CP*TP*GP*(3DR)P*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... 著者 Yang, W, Wang, F. 登録日 2009-10-07 公開日 2010-02-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structural insight into translesion synthesis by DNA Pol II. Cell(Cambridge,Mass.), 139, 2009
5TFR	Crystal structure of Zika Virus NS5 protein 分子名称: Genome polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION 著者 Longenecker, K.L, Upadhyay, A.K. 登録日 2016-09-26 公開日 2016-10-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Crystal structure of full-length Zika virus NS5 protein reveals a conformation similar to Japanese encephalitis virus NS5. Acta Crystallogr F Struct Biol Commun, 73, 2017
6AQR	SAGA DUB module Ubp8(C146A)/Sgf11/Sus1/Sgf73 bound to monoubiquitin 分子名称: Polyubiquitin-C, SAGA-associated factor 11, SAGA-associated factor 73, ... 著者 Morrow, M.E, Morgan, M.T, Wolberger, C. 登録日 2017-08-21 公開日 2018-07-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Active site alanine mutations convert deubiquitinases into high-affinity ubiquitin-binding proteins. EMBO Rep., 19, 2018
7K9Y	GsI-IIC RT Template-Switching Complex (twinned) 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*TP*CP*CP*AP*GP*GP*CP*AP*AP*C)-3'), MAGNESIUM ION, ... 著者 Stamos, J.L, Lentzsch, A.M. 登録日 2020-09-29 公開日 2021-08-18 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for template switching by a group II intron-encoded non-LTR-retroelement reverse transcriptase. J.Biol.Chem., 297, 2021
2DRA	Complex structure of CCA-adding enzyme with tRNAminiDCC and ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CCA-adding enzyme, MAGNESIUM ION, ... 著者 Tomita, K, Ishitani, R, Fukai, S, Nureki, O. 登録日 2006-06-08 公開日 2006-11-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Complete crystallographic analysis of the dynamics of CCA sequence addition Nature, 443, 2006
2DRB	Complex structure of CCA-adding enzyme with tRNAminiCCA 分子名称: CCA-adding enzyme, SULFATE ION, tRNA (35-MER) 著者 Tomita, K, Ishitani, R, Fukai, S, Nureki, O. 登録日 2006-06-08 公開日 2006-11-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Complete crystallographic analysis of the dynamics of CCA sequence addition Nature, 443, 2006

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