PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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1W7D	NMR Structure of Fasciclin-Like Protein From Rhodobacter sphaeroides 分子名称: BETA-IG-H3/FASCICLIN 著者 Moody, R, Phillips-Jones, M.K, Williamson, M.P. 登録日 2004-09-01 公開日 2006-03-08 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Structure and Function of a Bacterial Fasciclin I Domain Protein Elucidates Function of Related Cell Adhesion Proteins Such as Tgfbip and Periostin. FEBS Open Bio, 3, 2013
1VDR	DIHYDROFOLATE REDUCTASE 分子名称: DIHYDROFOLATE REDUCTASE, PHOSPHATE ION 著者 Pieper, U, Herzberg, O. 登録日 1997-11-30 公開日 1998-02-25 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural features of halophilicity derived from the crystal structure of dihydrofolate reductase from the Dead Sea halophilic archaeon, Haloferax volcanii. Structure, 6, 1998
8SM2	Crystal Structure of the macaque FcalphaRI bound to macaque IgA Fc. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ig-like domain-containing protein, Immunoglobulin subtype domain-containing protein, ... 著者 Tolbert, W.D, Pazgier, M. 登録日 2023-04-25 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Crystal Structure of the macaque FcalphaRI bound to macaque IgA Fc. To Be Published
1W27	Phenylalanine ammonia-lyase (PAL) from Petroselinum crispum 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, PHENYLALANINE AMMONIA-LYASE 1 著者 Ritter, H, Schulz, G.E. 登録日 2004-06-29 公開日 2004-11-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Basis for the Entrance Into the Phenylpropanoid Metabolism Catalyzed by Phenylalanine Ammonia-Lyase Plant Cell, 16, 2004
8E5M	Structure of ARG1 complex with pyrrolidine-based non-boronic acid inhibitor 6 分子名称: 1-{[(3S,4S)-3-({4-[2-(4-fluorobenzene-1-sulfonyl)ethyl]piperidin-1-yl}methyl)-4-(3-fluorophenyl)pyrrolidin-1-yl]methyl}cyclopentane-1-carboxylic acid, Arginase-1, MANGANESE (II) ION 著者 Palte, R.L, Gathiaka, S. 登録日 2022-08-22 公開日 2023-03-08 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Discovery of non-boronic acid Arginase 1 inhibitors through virtual screening and biophysical methods. Bioorg.Med.Chem.Lett., 84, 2023
7QFV	Crystal structure of KLK6 in complex with compound 17a 分子名称: KLK6 Activity-Based Probe (Ahx-DPhe-Ser(Z)-Dht-Arg-DPP), Kallikrein-6 著者 Jagtap, P.K.A, Zhang, L, De Vita, E, Tate, E.W, Hennig, J. 登録日 2021-12-06 公開日 2022-10-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 A KLK6 Activity-Based Probe Reveals a Role for KLK6 Activity in Pancreatic Cancer Cell Invasion. J.Am.Chem.Soc., 144, 2022
7QFT	Crystal structure of KLK6 in complex with compound 16a 分子名称: KLK6 Activity-Based Probe (Ahx-DPhe-Cha-Dht-Arg-DPP), Kallikrein-6 著者 Jagtap, P.K.A, Zhang, L, De Vita, E, Tate, E.W, Hennig, J. 登録日 2021-12-06 公開日 2022-11-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 A KLK6 Activity-Based Probe Reveals a Role for KLK6 Activity in Pancreatic Cancer Cell Invasion. J.Am.Chem.Soc., 144, 2022
1W9N	Isolation and characterization of epilancin 15X, a novel antibiotic from a clinical strain of Staphylococcus epidermidis 分子名称: EPILANCIN 15X 著者 Ekkelenkamp, M, Hanssen, M.G.M, Hsu, S.-T.D, de Jong, A, Milatovic, D, Verhoef, J, van Nuland, N.A.J. 登録日 2004-10-14 公開日 2005-04-01 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Isolation and structural characterization of epilancin 15X, a novel lantibiotic from a clinical strain of Staphylococcus epidermidis. FEBS Lett., 579, 2005
7R1R	RIBONUCLEOTIDE REDUCTASE E441Q MUTANT R1 PROTEIN FROM ESCHERICHIA COLI 分子名称: RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN 著者 Eriksson, M, Eklund, H. 登録日 1997-09-17 公開日 1998-03-18 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 A new mechanism-based radical intermediate in a mutant R1 protein affecting the catalytically essential Glu441 in Escherichia coli ribonucleotide reductase. J.Biol.Chem., 272, 1997
6QS9	Bovine Serum Albumin in complex with Ketoprofen 分子名称: (R)-Ketoprofen, CALCIUM ION, Serum albumin 著者 Donini, S, Parisini, E. 登録日 2019-02-20 公開日 2019-09-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.802 Å) 主引用文献 Biohybrid Electrospun Membrane for the Filtration of Ketoprofen Drug from Water. Acs Omega, 4, 2019
7RJ3	Crystal Structure of the Forkhead Associated (FHA) Domain of the Glycogen Accumulation Regulator (GarA) from Mycobacterium tuberculosis 分子名称: DI(HYDROXYETHYL)ETHER, Glycogen accumulation regulator GarA 著者 Minasov, G, Shuvalova, L, Pshenychnyi, S, Dubrovska, I, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2021-07-20 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Crystal Structure of the Forkhead Associated (FHA) Domain of the Glycogen Accumulation Regulator (GarA) from Mycobacterium tuberculosis. To Be Published
5CWR	Crystal Structure of human DNA polymerase lambda L431A mutant in complex with a one nucleotide DNA gap and dCTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), ... 著者 Liu, M.S, Tsai, M.D. 登録日 2015-07-28 公開日 2016-02-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda J.Am.Chem.Soc., 138, 2016
7RCR	Crystal Structure of the refolded Hemagglutinin head domain of Influenza A virus A/Ohio/09/2015 分子名称: 1,2-ETHANEDIOL, Hemagglutinin 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-07-08 公開日 2021-08-04 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structure of the refolded Hemagglutinin head domain of Influenzavirus A Influenza A virus A/Ohio/09/2015 to be published
7RAL	SARS-CoV-2 S bound to S2X259 Fab (local refinement of the RBD/S2X259 variable domains) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, S2X259 Fab heavy chain, S2X259 Fab light chain, ... 著者 Veesler, D, Tortorici, M.A, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-07-01 公開日 2021-08-04 最終更新日 2021-09-15 実験手法 ELECTRON MICROSCOPY 主引用文献 Broad sarbecovirus neutralization by a human monoclonal antibody. Nature, 597, 2021
6QZV	DPP9 bound to a dipeptide (MP) from the N-terminus of BRCA2 分子名称: Dipeptidyl peptidase 9, MET-PRO 著者 Ross, B, Geiss-Friedlander, R, Huber, R. 登録日 2019-03-12 公開日 2020-09-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Dipeptidyl peptidase 9 triggers BRCA2 degradation by the N-degron pathway to promote DNA-damage repair Biorxiv, 2020
2G9V	The crystal structure of glycogen phosphorylase in complex with (3R,4R,5R)-5-hydroxymethylpiperidine-3,4-diol and phosphate 分子名称: 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, Glycogen phosphorylase, muscle form, ... 著者 Oikonomakos, N.G, Tiraidis, C, Leonidas, D.D, Zographos, S.E. 登録日 2006-03-07 公開日 2007-01-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition. J.Med.Chem., 49, 2006
8SD4	Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule fusion inhibitor compound 7 分子名称: (S~1~S)-N-{3,5-dichloro-4-[(2S)-2-phenylmorpholine-4-carbonyl]phenyl}-3-[(dimethylamino)methyl]azetidine-1-sulfonimidoyl fluoride, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... 著者 Kadam, R.U, Zhu, X, Wilson, I.A. 登録日 2023-04-06 公開日 2024-06-05 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proc.Natl.Acad.Sci.USA, 121, 2024
8SD2	Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule fusion inhibitor compound 4 分子名称: (S~6~S)-N-{3-chloro-4-[(2S)-2-phenylmorpholine-4-carbonyl]phenyl}-5,7-dihydro-6H-pyrrolo[3,4-b]pyridine-6-sulfonimidoyl fluoride, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Kadam, R.U, Zhu, X.Y, Wilson, I.A. 登録日 2023-04-06 公開日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proc.Natl.Acad.Sci.USA, 121, 2024
7RNJ	S2P6 Fab fragment bound to the SARS-CoV/SARS-CoV-2 spike stem helix peptide 分子名称: Monoclonal antibody S2P6 Fab heavy chain, Monoclonal antibody S2P6 Fab light chain, SULFATE ION, ... 著者 Snell, G, Czudnochowski, N, Croll, T.I, Nix, J.C, Corti, D, Cameroni, E, Pinto, D, Beltramello, M, Sauer, M.M, Veesler, D. 登録日 2021-07-29 公開日 2021-08-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Broad betacoronavirus neutralization by a stem helix-specific human antibody. Science, 373, 2021
7RNN	Human ASIC1a-Nb.C1 complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, Nanobodies Nb.C1 著者 Wu, Y, Chen, Z, Sigworth, F.J, Canessa, C.M. 登録日 2021-07-29 公開日 2021-08-11 最終更新日 2021-08-25 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Structure and analysis of nanobody binding to the human ASIC1a ion channel. Elife, 10, 2021
7RTK	Structure of the (NIAU)2 complex with N-terminal mutation of ISCU2 Y35D at 2.5 A resolution 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ... 著者 Boniecki, M.T, Cygler, M. 登録日 2021-08-13 公開日 2021-08-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The essential function of ISCU2 and its conserved N-terminus in Fe/S cluster biogenesis To Be Published
2G9Q	The crystal structure of the glycogen phosphorylase b- 1AB complex 分子名称: 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL, Glycogen phosphorylase, muscle form, ... 著者 Oikonomakos, N.G, Tiraidis, C, Leonidas, D.D, Zographos, S.E, Kristiansen, M, Agius, L. 登録日 2006-03-07 公開日 2007-01-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition. J.Med.Chem., 49, 2006
7REI	The crystal structure of nickel bound human ADO C18S C239S variant 分子名称: 2-aminoethanethiol dioxygenase, GLYCEROL, NICKEL (II) ION 著者 Wang, Y, Shin, I, Li, J, Liu, A. 登録日 2021-07-12 公開日 2021-09-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Crystal structure of human cysteamine dioxygenase provides a structural rationale for its function as an oxygen sensor. J.Biol.Chem., 297, 2021
2YLA	INHIBITION OF THE PNEUMOCOCCAL VIRULENCE FACTOR STRH AND MOLECULAR INSIGHTS INTO N-GLYCAN RECOGNITION AND HYDROLYSIS 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Pluvinage, B, Higgins, M.A, Abbott, D.W, Robb, C, Dalia, A.B, Deng, L, Weiser, J.N, Parsons, T.B, Fairbanks, A.J, Vocadlo, D.J, Boraston, A.B. 登録日 2011-06-01 公開日 2011-09-07 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Inhibition of the Pneumococcal Virulence Factor Strh and Molecular Insights Into N-Glycan Recognition and Hydrolysis. Structure, 19, 2011
7RIJ	[I11G]hyen D 分子名称: ACETATE ION, Cyclotide hyen-D, D-[I11L]hyen D 著者 Du, Q, Huang, Y.H, Wang, C.K, Craik, D.J. 登録日 2021-07-20 公開日 2021-09-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Enabling efficient folding and high-resolution crystallographic analysis of bracelet cyclotides Molecules, 26(18), 2021

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