2I61
Depressant anti-insect neurotoxin, LqhIT2 from Leiurus quinquestriatus hebraeus
Summary for 2I61
Entry DOI | 10.2210/pdb2i61/pdb |
Descriptor | Insect toxin 2, LITHIUM ION, SULFATE ION, ... (7 entities in total) |
Functional Keywords | scorpion toxin, depressant, anti-insect, sodium channel modifer, toxin |
Biological source | Leiurus quinquestriatus hebraeus |
Cellular location | Secreted: Q26292 |
Total number of polymer chains | 1 |
Total formula weight | 7312.96 |
Authors | Frolow, F.,Gurevitz, M.,Karbat, I.,Turkov, M.,Gordon, D. (deposition date: 2006-08-27, release date: 2006-12-26, Last modification date: 2023-08-30) |
Primary citation | Karbat, I.,Turkov, M.,Cohen, L.,Kahn, R.,Gordon, D.,Gurevitz, M.,Frolow, F. X-ray Structure and Mutagenesis of the Scorpion Depressant Toxin LqhIT2 Reveals Key Determinants Crucial for Activity and Anti-Insect Selectivity. J.Mol.Biol., 366:586-601, 2007 Cited by PubMed: 17166514DOI: 10.1016/j.jmb.2006.10.085 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
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