9AUA
 
 | | PLP-dependent BesB holoenzyme | | 分子名称: | (3E)-4-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}-2-oxobut-3-enoic acid, 1,2-ETHANEDIOL, ACETATE ION, ... | | 著者 | Hedges, J.B, Ryan, K.S. | | 登録日 | 2024-02-28 | | 公開日 | 2025-07-02 | | 最終更新日 | 2025-07-09 | | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | | 主引用文献 | Terminal alkyne formation by a pyridoxal phosphate-dependent enzyme.
Nat.Chem.Biol., 2025
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7RY8
 | | S. CEREVISIAE CYP51 Y140H mutant COMPLEXED WITH Voriconazole | | 分子名称: | Lanosterol 14-alpha demethylase, PENTAETHYLENE GLYCOL, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Graham, D.O, Wilson, R.K, Ruma, Y.N, Keniya, M.V, Tyndall, J.D, Monk, B.C. | | 登録日 | 2021-08-24 | | 公開日 | 2021-09-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Structural Insights into the Azole Resistance of the Candida albicans Darlington Strain Using Saccharomyces cerevisiae Lanosterol 14 alpha-Demethylase as a Surrogate.
J Fungi (Basel), 7, 2021
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8ZSW
 | | Crystal Structure of Human DDB1, a Component of the E3 Ubiquitin Ligase Complex | | 分子名称: | ACETATE ION, DNA damage-binding protein 1 | | 著者 | Lee, J, Gil, Y, Jeong, Y.R, Jo, I. | | 登録日 | 2024-06-05 | | 公開日 | 2025-06-11 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Improved-Resolution Crystal Structure of Human DDB1, a Component of the E3 Ubiquitin Ligase Complex
To Be Published
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8ZUB
 | | The Crystal structure of mol075 bound to the main protease (3CLpro/Mpro) of SARS-CoV-2 | | 分子名称: | 3C-like proteinase, 6-[(6-chloranyl-2-pentyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]pyrimidine-2,4-dione | | 著者 | Yan, M, Zhang, H. | | 登録日 | 2024-06-08 | | 公開日 | 2025-06-11 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Development of pyrimidone derivatives as nonpeptidic and noncovalent 3-chymotrypsin-like protease (3CL pro ) inhibitors with anti-coronavirus activities.
Bioorg.Chem., 154, 2025
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1KTD
 | | CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IEK BOUND TO PIGEON CYTOCHROME C PEPTIDE | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion protein consisting of cytochrome C peptide, glycine rich linker, ... | | 著者 | Fremont, D.H, Dai, S, Chiang, H, Crawford, F, Marrack, P, Kappler, J. | | 登録日 | 2002-01-15 | | 公開日 | 2002-05-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis of cytochrome c presentation by IE(k).
J.Exp.Med., 195, 2002
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2V3D
 | | acid-beta-glucosidase with N-butyl-deoxynojirimycin | | 分子名称: | (2R,3R,4R,5S)-1-BUTYL-2-(HYDROXYMETHYL)PIPERIDINE-3,4,5-TRIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUCOSYLCERAMIDASE, ... | | 著者 | Brumshtein, B, Greenblatt, H.M, Butters, T.D, Shaaltiel, Y, Aviezer, D, Silman, I, Futerman, A.H, Sussman, J.L. | | 登録日 | 2007-06-17 | | 公開日 | 2007-08-14 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Crystal Structures of Complexes of N-Butyl- and N-Nonyl-Deoxynojirimycin Bound to Acid Beta-Glucosidase: Insights Into the Mechanism of Chemical Chaperone Action in Gaucher Disease.
J.Biol.Chem., 282, 2007
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8ZDP
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2I4T
 | | Crystal structure of Purine Nucleoside Phosphorylase from Trichomonas vaginalis with Imm-A | | 分子名称: | 3,4-PYRROLIDINEDIOL,2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)-2S,3S,4R,5R, PHOSPHATE ION, Trichomonas vaginalis purine nucleoside phosphorylase | | 著者 | Rinaldo-Matthis, A, Schramm, V.L, Almo, S.C. | | 登録日 | 2006-08-22 | | 公開日 | 2007-06-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | Inhibition and structure of Trichomonas vaginalis purine nucleoside phosphorylase with picomolar transition state analogues.
Biochemistry, 46, 2007
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8ZDH
 | | Cryo-EM structure of Mycobacteriophage Douge genome-packed capsid (gp8 and gp113) | | 分子名称: | Capsid Cement Protein (gp113), Major Capsid Protein (gp8) | | 著者 | Maharana, J, Wang, C.H, Tsai, L.A, Lowary, T.L, Ho, M.C. | | 登録日 | 2024-05-02 | | 公開日 | 2025-06-25 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mycobacteriophage cryo-EM studies reveal the siphophage architecture at the amino acid level and its host interaction for viral genome ejection
To Be Published
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2V8E
 | | Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand. | | 分子名称: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, CHLORIDE ION, COMPLEMENT FACTOR H, ... | | 著者 | Prosser, B.E, Johnson, S, Roversi, P, Herbert, A.P, Blaum, B.S, Tyrrell, J, Jowitt, T.A, Clark, S.J, Tarelli, E, Uhrin, D, Barlow, P.N, Sim, R.B, Day, A.J, Lea, S.M. | | 登録日 | 2007-08-07 | | 公開日 | 2007-10-02 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Basis for Complement Factor H Linked Age-Related Macular Degeneration.
J.Exp.Med., 204, 2007
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8ZDN
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8ZDQ
 | | Cryo-EM structure of Mycobacteriophage Douge complete baseplate (gp13, gp17, gp23, gp16, gp18 and gp20) | | 分子名称: | Baseplate Hub Protein (gp18), Baseplate Upper Protein (gp23), Central Fiber Protein (gp20), ... | | 著者 | Maharana, J, Wang, C.H, Tsai, L.A, Lowary, T.L, Ho, M.C. | | 登録日 | 2024-05-02 | | 公開日 | 2025-06-25 | | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | | 主引用文献 | Mycobacteriophage cryo-EM studies reveal the siphophage architecture at the amino acid level and its host interaction for viral genome ejection
To Be Published
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2I5S
 | | Crystal structure of onconase with bound nucleic acid | | 分子名称: | 5'-D(*A*(DU)P*GP*A)-3', P-30 protein | | 著者 | Bae, E, Lee, J.E, Raines, R.T, Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2006-08-25 | | 公開日 | 2006-09-05 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis for catalysis by onconase.
J.Mol.Biol., 375, 2008
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8ZPQ
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5JVG
 | | The large ribosomal subunit from Deinococcus radiodurans in complex with avilamycin | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 23S ribosomal RNA, 50S ribosomal protein L11, ... | | 著者 | Krupkin, M, Wekselman, I, Matzov, D, Eyal, Z, Diskin Posner, Y, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A. | | 登録日 | 2016-05-11 | | 公開日 | 2016-11-09 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3.428 Å) | | 主引用文献 | Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding.
Proc.Natl.Acad.Sci.USA, 113, 2016
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2V8K
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8ZRS
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8ZWS
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2I5W
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8ZDJ
 | | Cryo-EM structure of Mycobacteriophage Douge genome-packed connector (gp5, gp9, gp10, gp12 and gp13) | | 分子名称: | Adaptor Protein (gp9), Portal Protein (gp5), Stopper Protein (gp10), ... | | 著者 | Maharana, J, Wang, C.H, Tsai, L.A, Lowary, T.L, Ho, M.C. | | 登録日 | 2024-05-02 | | 公開日 | 2025-06-25 | | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | | 主引用文献 | Mycobacteriophage cryo-EM studies reveal the siphophage architecture at the amino acid level and its host interaction for viral genome ejection
To Be Published
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2VBM
 | | Tailspike protein of bacteriophage Sf6 complexed with tetrasaccharide | | 分子名称: | MAGNESIUM ION, MANGANESE (II) ION, PHOSPHATE ION, ... | | 著者 | Mueller, J.J, Barbirz, S, Freiberg, A, Seckler, R, Heinemann, U. | | 登録日 | 2007-09-14 | | 公開日 | 2008-04-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | An Intersubunit Active Site between Supercoiled Parallel Beta Helices in the Trimeric Tailspike Endorhamnosidase of Shigella Flexneri Phage Sf6.
Structure, 16, 2008
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8ZEA
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2VDR
 | | Integrin AlphaIIbBeta3 Headpiece Bound to a chimeric Fibrinogen Gamma chain peptide, LGGAKQRGDV | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN, ... | | 著者 | Springer, T.A, Zhu, J, Xiao, T. | | 登録日 | 2007-10-10 | | 公開日 | 2008-09-02 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
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1KW8
 | | Crystal structure of BphC-2,3-dihydroxybiphenyl-NO complex | | 分子名称: | 2,3-Dihydroxybiphenyl dioxygenase, BIPHENYL-2,3-DIOL, FE (II) ION, ... | | 著者 | Sato, N, Uragami, Y, Nishizaki, T, Takahashi, Y, Sazaki, G, Sugimoto, K, Nonaka, T, Masai, E, Fukuda, M, Senda, T. | | 登録日 | 2002-01-29 | | 公開日 | 2003-01-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structures of the Reaction Intermediate and its Homologue of an Extradiol-cleaving Catecholic Dioxygenase
J.Mol.Biol., 321, 2002
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1KWV
 | | Rat mannose binding protein A complexed with a-Me-GlcNAc | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I. | | 登録日 | 2002-01-30 | | 公開日 | 2002-07-05 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.
J.Biol.Chem., 277, 2002
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