2I4T

Crystal structure of Purine Nucleoside Phosphorylase from Trichomonas vaginalis with Imm-A

Summary for 2I4T

Entry DOI	10.2210/pdb2i4t/pdb
Descriptor	Trichomonas vaginalis purine nucleoside phosphorylase, PHOSPHATE ION, 3,4-PYRROLIDINEDIOL,2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)-2S,3S,4R,5R, ... (4 entities in total)
Functional Keywords	purine nucleoside phosphorylase, transferase
Biological source	Trichomonas vaginalis
Total number of polymer chains	3
Total formula weight	79126.08
Authors	Rinaldo-Matthis, A.,Schramm, V.L.,Almo, S.C. (deposition date: 2006-08-22, release date: 2007-06-05, Last modification date: 2024-02-21)
Primary citation	Rinaldo-Matthis, A.,Wing, C.,Ghanem, M.,Deng, H.,Wu, P.,Gupta, A.,Tyler, P.C.,Evans, G.B.,Furneaux, R.H.,Almo, S.C.,Wang, C.C.,Schramm, V.L. Inhibition and structure of Trichomonas vaginalis purine nucleoside phosphorylase with picomolar transition state analogues. Biochemistry, 46:659-668, 2007 Cited by PubMed: 17223688 DOI: 10.1021/bi061515r PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.74 Å)

Structure validation