2I4T
Crystal structure of Purine Nucleoside Phosphorylase from Trichomonas vaginalis with Imm-A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| A | 0004850 | molecular_function | uridine phosphorylase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| A | 0006218 | biological_process | uridine catabolic process |
| A | 0009116 | biological_process | nucleoside metabolic process |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| B | 0004850 | molecular_function | uridine phosphorylase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| B | 0006218 | biological_process | uridine catabolic process |
| B | 0009116 | biological_process | nucleoside metabolic process |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| C | 0004850 | molecular_function | uridine phosphorylase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| C | 0006218 | biological_process | uridine catabolic process |
| C | 0009116 | biological_process | nucleoside metabolic process |
| C | 0016757 | molecular_function | glycosyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 C 238 |
| Chain | Residue |
| C | CYS19 |
| C | GLY20 |
| C | ASP21 |
| C | ARG43 |
| C | ARG87 |
| C | GLY89 |
| C | THR90 |
| C | UA2242 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 A 239 |
| Chain | Residue |
| A | ARG24 |
| A | ARG87 |
| A | GLY89 |
| A | THR90 |
| A | UA2243 |
| B | ARG43 |
| A | GLY20 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 B 240 |
| Chain | Residue |
| A | ARG43 |
| B | CYS19 |
| B | GLY20 |
| B | ARG24 |
| B | ARG87 |
| B | THR90 |
| B | UA2241 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 C 241 |
| Chain | Residue |
| A | THR107 |
| A | GLY151 |
| C | THR128 |
| C | SER130 |
| C | PHE131 |
| C | ASP190 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 242 |
| Chain | Residue |
| A | PRO22 |
| A | ARG43 |
| A | ILE45 |
| A | GLY63 |
| B | ARG43 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE UA2 B 241 |
| Chain | Residue |
| A | HIS4 |
| A | ARG43 |
| B | MET64 |
| B | ARG87 |
| B | THR90 |
| B | CYS91 |
| B | GLY92 |
| B | PHE159 |
| B | VAL178 |
| B | GLU179 |
| B | MET180 |
| B | GLU181 |
| B | SER203 |
| B | ASP204 |
| B | PO4240 |
| B | HOH263 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE UA2 C 242 |
| Chain | Residue |
| C | HIS4 |
| C | ARG43 |
| C | ARG87 |
| C | THR90 |
| C | CYS91 |
| C | PHE159 |
| C | VAL178 |
| C | GLU179 |
| C | MET180 |
| C | GLU181 |
| C | ASP204 |
| C | ILE206 |
| C | PO4238 |
| C | HOH256 |
| site_id | AC8 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE UA2 A 243 |
| Chain | Residue |
| A | MET64 |
| A | ARG87 |
| A | THR90 |
| A | CYS91 |
| A | GLY92 |
| A | PHE159 |
| A | VAL178 |
| A | GLU179 |
| A | MET180 |
| A | GLU181 |
| A | ASP204 |
| A | PO4239 |
| B | HIS4 |
| B | ARG43 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a69 |
| Chain | Residue | Details |
| A | ASP204 | |
| A | ARG217 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a69 |
| Chain | Residue | Details |
| B | ASP204 | |
| B | ARG217 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a69 |
| Chain | Residue | Details |
| C | ASP204 |
