2I5S

Crystal structure of onconase with bound nucleic acid

Summary for 2I5S

• Entry DOI: 10.2210/pdb2i5s/pdb
• Related: 2GMK
• Descriptor: P-30 protein, 5'-D(*A*(DU)P*GP*A)-3' (3 entities in total)
• Functional Keywords: onconase, p-30 protein, ribonuclease, anti-tumor, structural genomics, psi-2, protein structure initiative, center for eukaryotic structural genomics, cesg, hydrolase-dna complex, hydrolase/dna
• Biological source: Rana pipiens (northern leopard frog)
• Total number of polymer chains: 2
• Total formula weight: 13046.48

Authors

Bae, E.,Lee, J.E.,Raines, R.T.,Wesenberg, G.E.,Phillips Jr., G.N.,Bitto, E.,Bingman, C.A.,Center for Eukaryotic Structural Genomics (CESG) (deposition date: 2006-08-25, release date: 2006-09-05, Last modification date: 2023-08-30)

• Primary citation: Lee, J.E.,Bae, E.,Bingman, C.A.,Phillips Jr., G.N.,Raines, R.T.; Structural basis for catalysis by onconase.; J.Mol.Biol., 375:165-177, 2008; PubMed: 18001769; DOI: 10.1016/j.jmb.2007.09.089

Experimental method

X-RAY DIFFRACTION (1.9 Å)