3QO4
 
 | | The Crystal Structure of Death Receptor 6 | | 分子名称: | ACETATE ION, SULFATE ION, Tumor necrosis factor receptor superfamily member 21 | | 著者 | Kuester, M, Kemmerzehl, S, Dahms, S.O, Roeser, D, Than, M.E. | | 登録日 | 2011-02-09 | | 公開日 | 2011-05-18 | | 最終更新日 | 2012-02-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The crystal structure of death receptor 6 (DR6): a potential receptor of the amyloid precursor protein (APP).
J.Mol.Biol., 409, 2011
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6JJJ
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4IXW
 | | Halohydrin dehalogenase (HheC) bound to ethyl (2S)-oxiran-2-ylacetate | | 分子名称: | CHLORIDE ION, Halohydrin dehalogenase, ethyl (2S)-oxiran-2-ylacetate | | 著者 | Floor, R.J, Schallmey, M, Hauer, B, Breuer, M, Jekel, P.A, Wijma, H.J, Dijkstra, B.W, Janssen, D.B. | | 登録日 | 2013-01-28 | | 公開日 | 2013-02-20 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Biocatalytic and structural properties of a highly engineered halohydrin dehalogenase.
Chembiochem, 14, 2013
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7OJ1
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4IY1
 | | Structure of a 37-fold mutant of halohydrin dehalogenase (HheC) with chloride bound | | 分子名称: | CHLORIDE ION, Halohydrin dehalogenase | | 著者 | Floor, R.J, Schallmey, M, Hauer, B, Breuer, M, Jekel, P.A, Wijma, H.J, Dijkstra, B.W, Janssen, D.B. | | 登録日 | 2013-01-28 | | 公開日 | 2013-02-20 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Biocatalytic and structural properties of a highly engineered halohydrin dehalogenase.
Chembiochem, 14, 2013
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2HYE
 | | Crystal Structure of the DDB1-Cul4A-Rbx1-SV5V Complex | | 分子名称: | Cullin-4A, DNA damage-binding protein 1, Nonstructural protein V, ... | | 著者 | Angers, S, Li, T, Yi, X, MacCoss, M.J, Moon, R.T, Zheng, N. | | 登録日 | 2006-08-05 | | 公開日 | 2006-10-03 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery.
Nature, 443, 2006
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2ERJ
 | | Crystal structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Debler, E.W, Stauber, D.J, Wilson, I.A. | | 登録日 | 2005-10-25 | | 公開日 | 2006-02-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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4DG9
 | | Structure of holo-PA1221, an NRPS protein containing adenylation and PCP domains bound to vinylsulfonamide inhibitor | | 分子名称: | 5'-({[(2R,3R)-3-amino-2-{[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-{[oxido(oxo)phosphonio]oxy}butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}-4-methylpentyl]sulfonyl}amino)-5'-deoxyadenosine, PA1221 | | 著者 | Mitchell, C.A, Shi, C, Aldrich, C.C, Gulick, A.M. | | 登録日 | 2012-01-25 | | 公開日 | 2012-05-02 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structure of PA1221, a Nonribosomal Peptide Synthetase Containing Adenylation and Peptidyl Carrier Protein Domains.
Biochemistry, 51, 2012
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4IXT
 | | Structure of a 37-fold mutant of halohydrin dehalogenase (HheC) bound to ethyl (R)-4-cyano-3-hydroxybutyrate | | 分子名称: | CHLORIDE ION, Halohydrin dehalogenase, ethyl (3R)-4-cyano-3-hydroxybutanoate | | 著者 | Floor, R.J, Schallmey, M, Hauer, B, Breuer, M, Jekel, P.A, Wijma, H.J, Dijkstra, B.W, Janssen, D.B. | | 登録日 | 2013-01-28 | | 公開日 | 2013-02-20 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Biocatalytic and structural properties of a highly engineered halohydrin dehalogenase.
Chembiochem, 14, 2013
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4H0P
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3LPW
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4ZFO
 | | J22.9-xi: chimeric mouse/human antibody against human BCMA (CD269) | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COPPER (II) ION, J22.9-xi Fab, ... | | 著者 | Marino, S.F, Daumke, O, Olal, D. | | 登録日 | 2015-04-21 | | 公開日 | 2015-05-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.895 Å) | | 主引用文献 | Potent anti-tumor response by targeting B cell maturation antigen (BCMA) in a mouse model of multiple myeloma.
Mol Oncol, 9, 2015
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3V7Q
 | | Crystal structure of B. subtilis YlxQ at 1.55 A resolution | | 分子名称: | CITRIC ACID, POTASSIUM ION, Probable ribosomal protein ylxQ | | 著者 | Baird, N.J, Zhang, J, Hamma, T, Ferre-D'Amare, A.R. | | 登録日 | 2011-12-21 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | YbxF and YlxQ are bacterial homologs of L7Ae and bind K-turns but not K-loops.
Rna, 18, 2012
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7P2B
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3NX1
 | | Crystal structure of Enterobacter sp. Px6-4 Ferulic Acid Decarboxylase | | 分子名称: | Ferulic acid decarboxylase | | 著者 | Gu, W, Yang, J.K, Lou, Z.Y, Meng, Z.H, Zhang, K.-Q. | | 登録日 | 2010-07-12 | | 公開日 | 2011-02-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Basis of Enzymatic Activity for the Ferulic Acid Decarboxylase (FADase) from Enterobacter sp. Px6-4
Plos One, 6, 2011
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5OFO
 | | Cryo EM structure of the E. coli disaggregase ClpB (BAP form, DWB mutant), in the ATPgammaS state, bound to the model substrate casein | | 分子名称: | Chaperone protein ClpB,ATP-dependent Clp protease ATP-binding subunit ClpA,Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | 著者 | Deville, C, Carroni, M, Franke, K.B, Topf, M, Bukau, B, Mogk, A, Saibil, H.R. | | 登録日 | 2017-07-11 | | 公開日 | 2017-08-16 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase.
Sci Adv, 3, 2017
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5OG1
 | | Cryo EM structure of the E. coli disaggregase ClpB (BAP form, DWB mutant), in the ATPgammaS state | | 分子名称: | Chaperone protein ClpB,ATP-dependent Clp protease ATP-binding subunit ClpA,Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | 著者 | Deville, C, Carroni, M, Franke, K.B, Topf, M, Bukau, B, Mogk, A, Saibil, H.R. | | 登録日 | 2017-07-11 | | 公開日 | 2017-08-16 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase.
Sci Adv, 3, 2017
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2CGL
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6EMI
 | | Crystal structure of a variant of human butyrylcholinesterase expressed in bacteria. | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Cholinesterase, ... | | 著者 | Brazzolotto, X, Igert, A, Guillon, V, Santoni, G, Nachon, F. | | 登録日 | 2017-10-02 | | 公開日 | 2017-11-08 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.476 Å) | | 主引用文献 | Bacterial Expression of Human Butyrylcholinesterase as a Tool for Nerve Agent Bioscavengers Development.
Molecules, 22, 2017
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3VW7
 | | Crystal structure of human protease-activated receptor 1 (PAR1) bound with antagonist vorapaxar at 2.2 angstrom | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, Proteinase-activated receptor 1, ... | | 著者 | Zhang, C, Srinivasan, Y, Arlow, D.H, Fung, J.J, Palmer, D, Zheng, Y, Green, H.F, Pandey, A, Dror, R.O, Shaw, D.E, Weis, W.I, Coughlin, S.R, Kobilka, B.K. | | 登録日 | 2012-08-07 | | 公開日 | 2012-12-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | High-resolution crystal structure of human protease-activated receptor 1
Nature, 492, 2012
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8CR8
 | | human Interleukin-23 | | 分子名称: | Interleukin-12 subunit beta, Interleukin-23 subunit alpha, TERBIUM(III) ION, ... | | 著者 | Bloch, Y, Savvides, S.N. | | 登録日 | 2023-03-08 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
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8D3F
 | | Crystal structure of human STAT1 in complex with the repeat region from Toxoplasma protein TgIST | | 分子名称: | Signal transducer and activator of transcription 1-alpha/beta,Inhibitor of STAT1-dependent transcription TgIST | | 著者 | Huang, Z, Liu, H, Nix, J.C, Amarasinghe, G.K, Sibley, L.D. | | 登録日 | 2022-06-01 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | | 主引用文献 | The intrinsically disordered protein TgIST from Toxoplasma gondii inhibits STAT1 signaling by blocking cofactor recruitment.
Nat Commun, 13, 2022
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8CVZ
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8CVY
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8CVX
 | | Human glycogenin-1 and glycogen synthase-1 complex in the presence of glucose-6-phosphate | | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose, Glycogen [starch] synthase, muscle, ... | | 著者 | Liu, Y, Fastman, N.M, Tzitzilonis, C. | | 登録日 | 2022-05-18 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | The structural mechanism of human glycogen synthesis by the GYS1-GYG1 complex.
Cell Rep, 40, 2022
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