PDB: 97814 件ウェブページステータス検索Chemie searchBIRD

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6ARN	F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with o-methoxyphenyl beta-galactoside (OMPG) 分子名称: 2-methoxyphenyl beta-D-galactopyranoside, Putative Fml fimbrial adhesin FmlD, SULFATE ION 著者 Kalas, V, Hultgren, S.J. 登録日 2017-08-22 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection. Proc.Natl.Acad.Sci.USA, 115, 2018
3RE7	Copper (II) loaded Bullfrog Ferritin M chain 分子名称: COPPER (II) ION, Ferritin, middle subunit 著者 Bertini, I, Lalli, D, Mangani, S, Pozzi, C, Rosa, C, Turano, P. 登録日 2011-04-02 公開日 2012-04-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 Structural insights into the ferroxidase site of ferritins from higher eukaryotes. J.Am.Chem.Soc., 134, 2012
5A09	Crystal Structure of human neutrophil elastase in complex with a dihydropyrimidone inhibitor 分子名称: 2-[(4R)-4-(4-cyanophenyl)-5-ethanoyl-6-methyl-2-oxidanylidene-1-[3-(trifluoromethyl)phenyl]-4H-pyrimidin-3-yl]ethanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, NEUTROPHIL ELASTASE, ... 著者 vonNussbaum, F, Li, V.M.-J, Allerheiligen, S, Anlauf, S, Baerfacker, L, Bechem, M, Delbeck, M, Fitzgerald, M.F, Gerisch, M, Gielen-Haertwig, H, Haning, H, Karthaus, D, Lang, D, Lustig, K, Meibom, D, Mittendorf, J, Rosentreter, U, Schaefer, M, Schaefer, S, Schamberger, J, Telan, L.A, Tersteegen, A. 登録日 2015-04-17 公開日 2015-08-19 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases. ChemMedChem, 10, 2015
5UEH	Structure of GSTO1 covalently conjugated to quinolinic acid fluorosulfate 分子名称: 2-(4-chlorophenyl)-6-[(fluorosulfonyl)oxy]quinoline-4-carboxylic acid, GLYCEROL, Glutathione S-transferase omega-1, ... 著者 Mortenson, D.E, Wilson, I.A, Kelly, J.W. 登録日 2017-01-02 公開日 2018-01-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 "Inverse Drug Discovery" Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates. J. Am. Chem. Soc., 140, 2018
1JT5	Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L73V/V109L) 分子名称: SULFATE ION, acidic fibroblast growth factor 著者 Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. 登録日 2001-08-20 公開日 2001-12-19 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil. Protein Sci., 10, 2001
2NBT	NEURONAL BUNGAROTOXIN, NMR, 10 STRUCTURES 分子名称: NEURONAL BUNGAROTOXIN 著者 Oswald, R.E, Sutcliffe, M.J, Bamberger, M, Loring, R.H, Braswell, E, Dobson, C.M. 登録日 1997-10-29 公開日 1998-03-11 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Solution structure of neuronal bungarotoxin determined by two-dimensional NMR spectroscopy: calculation of tertiary structure using systematic homologous model building, dynamical simulated annealing, and restrained molecular dynamics. Biochemistry, 31, 1992
3TWM	Crystal structure of Arabidopsis thaliana FPG 分子名称: 5'-D(*AP*GP*CP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*TP*GP*GP*TP*AP*GP*AP*CP*GP*TP*GP*GP*AP*CP*GP*C)-3', Formamidopyrimidine-DNA glycosylase 1 著者 Duclos, S, Aller, P, Wallace, S.S, Doublie, S. 登録日 2011-09-22 公開日 2012-07-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural and biochemical studies of a plant formamidopyrimidine-DNA glycosylase reveal why eukaryotic Fpg glycosylases do not excise 8-oxoguanine. Dna Repair, 11, 2012
3W13	Insulin receptor ectodomain construct comprising domains L1-CR in complex with high-affinity insulin analogue [D-PRO-B26]-DTI-NH2, alphact peptide(693-719) and FAB 83-7 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ... 著者 Lawrence, M.C, Smith, B.J, Brzozowski, A.M. 登録日 2012-11-06 公開日 2013-01-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (4.303 Å) 主引用文献 How insulin engages its primary binding site on the insulin receptor Nature, 493, 2013
1JT4	Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND VAL 109 REPLACED BY LEU (V109L) 分子名称: FORMIC ACID, acidic fibroblast growth factor 著者 Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. 登録日 2001-08-20 公開日 2001-12-19 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil. Protein Sci., 10, 2001
1JT7	Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L44F/L73V/V109L) 分子名称: FORMIC ACID, SULFATE ION, acidic fibroblast growth factor 著者 Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. 登録日 2001-08-20 公開日 2001-12-19 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil. Protein Sci., 10, 2001
3RBC	Bullfrog M ferritin with iron(III) bound to the ferroxidase site 分子名称: FE (III) ION, Ferritin, middle subunit 著者 Bertini, I, Lalli, D, Mangani, S, Pozzi, C, Rosa, C, Turano, P. 登録日 2011-03-29 公開日 2012-04-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural insights into the ferroxidase site of ferritins from higher eukaryotes. J.Am.Chem.Soc., 134, 2012
1HZW	CRYSTAL STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE 分子名称: PHOSPHATE ION, THYMIDYLATE SYNTHASE 著者 Almog, R, Waddling, C.A, Maley, F, Maley, G.F, Van Roey, P. 登録日 2001-01-26 公開日 2001-05-09 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of a deletion mutant of human thymidylate synthase Delta (7-29) and its ternary complex with Tomudex and dUMP. Protein Sci., 10, 2001
2YGE	E88G-N92L Mutant of N-Term HSP90 complexed with Geldanamycin 分子名称: ATP-DEPENDENT MOLECULAR CHAPERONE HSP82, GELDANAMYCIN, GLYCEROL 著者 Roe, M, Prodromou, C, Pearl, L.H. 登録日 2011-04-14 公開日 2011-11-16 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.956 Å) 主引用文献 Features of the Streptomyces Hygroscopicus Htpg Reveal How Partial Geldanamycin Resistance Can Arise by Mutation to the ATP Binding Pocket of a Eukaryotic Hsp90. Faseb J., 25, 2011
4E2R	Interactions of Ba2+ with a non-self-complementary Z-type DNA duplex 分子名称: BARIUM ION, DNA (5'-D(*CP*AP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*TP*G)-3') 著者 Mandal, P.K, Venkadesh, S, Gautham, N. 登録日 2012-03-09 公開日 2013-03-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Interactions of Ba2+ with a non-self-complementary Z-type DNA duplex To be Published
4HQV	tRNA-guanine transglycosylase Y106F, C158V, V233G mutant in complex with queuine 分子名称: 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ... 著者 Biela, I, Tidten-Luksch, N, Heine, A, Reuter, K, Klebe, G. 登録日 2012-10-26 公開日 2012-11-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor. Plos One, 8, 2013
3W12	Insulin receptor ectodomain construct comprising domains L1-CR in complex with high-affinity insulin analogue [D-PRO-B26]-DTI-NH2, alpha-CT peptide(704-719) and FAB 83-7 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ... 著者 Lawrence, M.C, Smith, B.J, Brzozowsk, A.M. 登録日 2012-11-06 公開日 2013-01-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (4.301 Å) 主引用文献 How insulin engages its primary binding site on the insulin receptor Nature, 493, 2013
4GY0	Round 18 Arylesterase Variant of Phosphotriesterase 分子名称: ZINC ION, arylesterase variant of phosphotriesterase 著者 Jackson, C.J, Tokuriki, N, Tawfik, D.S. 登録日 2012-09-05 公開日 2013-08-21 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme Nat Commun, 3, 2012
1JTC	Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE (L44F) 分子名称: FORMIC ACID, acidic fibroblast growth factor 著者 Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. 登録日 2001-08-20 公開日 2001-12-19 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil. Protein Sci., 10, 2001
3ROC	Crystal structure of human p38 alpha complexed with a pyrimidinone compound 分子名称: 3-{5-chloro-4-[(2,4-difluorobenzyl)oxy]-6-oxopyrimidin-1(6H)-yl}-N-(2-hydroxyethyl)-4-methylbenzamide, 4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine, Mitogen-activated protein kinase 14 著者 Shieh, H.-S, Xing, L. 登録日 2011-04-25 公開日 2011-06-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Substituted N-aryl-6-pyrimidinones: A new class of potent, selective, and orally active p38 MAP kinase inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
1JT3	Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Histidine Tag AND LEU 73 REPLACED BY VAL (L73V) 分子名称: SULFATE ION, acidic fibroblast growth factor 著者 Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. 登録日 2001-08-20 公開日 2001-12-19 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil. Protein Sci., 10, 2001
1JQZ	Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag. 分子名称: FORMIC ACID, acidic fibroblast growth factor 著者 Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. 登録日 2001-08-09 公開日 2001-12-19 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil. Protein Sci., 10, 2001
2HIG	Crystal Structure of Phosphofructokinase apoenzyme from Trypanosoma brucei. 分子名称: 6-phospho-1-fructokinase, SODIUM ION 著者 Martinez-Oyanedel, J, McNae, I.W, Fothergill-Gilmore, L.A, Walkinshaw, M.D. 登録日 2006-06-29 公開日 2007-02-13 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The First Crystal Structure of Phosphofructokinase from a Eukaryote: Trypanosoma brucei. J.Mol.Biol., 366, 2007
2DC1	Crystal Structure Of L-Aspartate Dehydrogenase From Hyperthermophilic Archaeon Archaeoglobus fulgidus 分子名称: CITRIC ACID, L-aspartate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Yoneda, K, Sakuraba, H, Tsuge, H, Ohshima, T. 登録日 2005-12-19 公開日 2006-12-26 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of archaeal highly thermostable L-aspartate dehydrogenase/NAD/citrate ternary complex. Febs J., 274, 2007
6DPZ	X-ray crystal structure of AmpC beta-lactamase with inhibitor 分子名称: (1R,2S)-2-{[(pyrrolidin-1-yl)sulfonyl]amino}cyclooctane-1-carboxylic acid, Beta-lactamase 著者 Singh, I. 登録日 2018-06-09 公開日 2018-07-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Ultra-large library docking for discovering new chemotypes. Nature, 566, 2019
6X46	NMR solution structure of Asterix/Gtsf1 from mouse (CHHC zinc finger domains) 分子名称: Gametocyte-specific factor 1, ZINC ION 著者 Ipsaro, J.J, O'Brien, P.A, Bhattacharya, S, Palmer III, A.G, Joshua-Tor, L. 登録日 2020-05-22 公開日 2021-03-03 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons. Cell Rep, 34, 2021

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